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ONTOLOGY REPORT - ANNOTATIONS


Term:decreased susceptibility to type I hypersensitivity reaction
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Accession:MP:0005597 term browser browse the term
Definition:less likelihood or resistance to developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks
Comment:Examples of this type of hypersensitivity include hay fever, asthma, and anaphylaxis.
Synonyms:exact_synonym: decreased susceptibility to anaphylactic shock;   decreased susceptibility to anaphylaxis;   decreased susceptibility to immediate type hypersensitivity;   increased resistance to anaphylactic shock;   increased resistance to anaphylaxis;   increased resistance to immediate type hypersensitivity;   increased resistance to type I hypersensitivity reaction;   reduced susceptibility to type I hypersensitivity reaction


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  mammalian phenotype 4926
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal adaptive immunity 35
          abnormal type I hypersensitivity reaction 0
            decreased susceptibility to type I hypersensitivity reaction 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 4926
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal inflammatory response 227
          abnormal acute inflammation 5
            abnormal type I hypersensitivity reaction 0
              decreased susceptibility to type I hypersensitivity reaction 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.