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ONTOLOGY REPORT - ANNOTATIONS


Term:decreased susceptibility to type III hypersensitivity reaction
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Accession:MP:0005614 term browser browse the term
Definition:less likelihood of or resistance to developing tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via Abs encountering circulating Ag; Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury
Comment:Examples of this include: Autoimmune diseases: systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren syndrome, scleroderma, and glomerulonephritis.
Synonyms:exact_synonym: decreased susceptibility to immune complex mediated hypersensitivity;   increased resistance to immune complex mediated hypersensitivity;   increased resistance to type III hypersensitivity reaction;   reduced susceptibility to type III hypersensitivity reaction


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Term Annotations click to browse term
  mammalian phenotype 4926
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal adaptive immunity 35
          abnormal type III hypersensitivity reaction 3
            decreased susceptibility to type III hypersensitivity reaction 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 4926
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal inflammatory response 227
          abnormal acute inflammation 5
            abnormal type III hypersensitivity reaction 3
              decreased susceptibility to type III hypersensitivity reaction 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.