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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:pulmonary fibrosis
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Accession:MP:0006050 term browser browse the term
Definition:formation of fibrous tissue within the lung often resulting from inflammation or injury
Synonyms:exact_synonym: lung fibrosis


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pulmonary fibrosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 IAGP MGI PMID:18442043 NCBI chr 1:90,203,980...90,215,724
Ensembl chr 1:90,203,980...90,216,751
JBrowse link
G Cd59a CD59a antigen IAGP MGI PMID:17429844 NCBI chr 2:104,095,753...104,115,410
Ensembl chr 2:104,095,801...104,115,354
JBrowse link
G Cish cytokine inducible SH2-containing protein IAGP MGI PMID:23727894 NCBI chr 9:107,296,659...107,302,784
Ensembl chr 9:107,296,026...107,302,784
JBrowse link
G Cox4i2 cytochrome c oxidase subunit 4I2 IAGP MGI PMID:22730437 NCBI chr 2:152,753,916...152,765,039
Ensembl chr 2:152,754,173...152,765,037
JBrowse link
G Cpb2 carboxypeptidase B2 (plasma) IAGP MGI PMID:16565485 NCBI chr14:75,242,287...75,283,555
Ensembl chr14:75,242,287...75,283,555
JBrowse link
G Ctsk cathepsin K IAGP MGI PMID:15161653 NCBI chr 3:95,499,210...95,509,387
Ensembl chr 3:95,499,256...95,509,362
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 IAGP MGI PMID:15328359 NCBI chr14:73,025,672...73,049,114
Ensembl chr14:73,025,603...73,049,114
JBrowse link
G Egr1 early growth response 1 IAGP MGI PMID:15289506, PMID:19679873 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IAGP MGI PMID:10470077 NCBI chr19:40,612,366...40,741,602
Ensembl chr19:40,612,366...40,741,602
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) IAGP MGI PMID:15148335 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Foxd1 forkhead box D1 IAGP MGI PMID:30830875 NCBI chr13:98,354,245...98,356,705
Ensembl chr13:98,354,242...98,359,305
JBrowse link
G Golga2 golgi autoantigen, golgin subfamily a, 2 IAGP MGI PMID:29128360 NCBI chr 2:32,288,287...32,307,913
Ensembl chr 2:32,287,384...32,307,921
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19217431 NCBI chr 6:113,067,428...113,077,244
Ensembl chr 6:113,067,428...113,077,333
JBrowse link
G Hck hemopoietic cell kinase IAGP MGI PMID:12208875 NCBI chr 2:153,108,468...153,151,441
Ensembl chr 2:153,108,468...153,151,441
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein IAGP MGI PMID:17717145 NCBI chr 2:152,736,251...152,737,410
Ensembl chr 2:152,736,251...152,737,410
JBrowse link
G Il13 interleukin 13 IAGP MGI PMID:11070175 NCBI chr11:53,631,323...53,634,702
Ensembl chr11:53,631,324...53,634,702
JBrowse link
G Itga3 integrin alpha 3 IAGP MGI PMID:19104148 NCBI chr11:95,044,475...95,076,844
Ensembl chr11:95,044,474...95,076,801
JBrowse link
G Lyst lysosomal trafficking regulator IAGP MGI PMID:15743322 NCBI chr13:13,590,311...13,778,803
Ensembl chr13:13,590,397...13,778,803
JBrowse link
G Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like IAGP MGI PMID:21300902 NCBI chr18:64,884,480...65,217,826
Ensembl chr18:64,887,705...65,217,828
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 IAGP MGI PMID:15208274 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nudt21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 IAGP MGI PMID:30830875 NCBI chr 8:94,019,403...94,037,039
Ensembl chr 8:94,015,496...94,037,031
JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide IAGP MGI PMID:19217431 NCBI chr 5:75,151,322...75,198,206
Ensembl chr 5:75,152,292...75,198,215
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta IAGP MGI PMID:23706742 NCBI chr 9:99,038,402...99,140,235
Ensembl chr 9:99,036,654...99,140,621
JBrowse link
G Pkn2 protein kinase N2 IAGP MGI PMID:26774483 NCBI chr 3:142,790,902...142,882,004
Ensembl chr 3:142,790,902...142,882,004
JBrowse link
G Plg plasminogen IAGP MGI PMID:7586361 NCBI chr17:12,378,609...12,419,384
Ensembl chr17:12,378,608...12,419,385
JBrowse link
G Psen2 presenilin 2 IAGP MGI PMID:10518543 NCBI chr 1:180,227,004...180,263,467
Ensembl chr 1:180,227,004...180,263,438
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B IAGP MGI PMID:7834753 NCBI chr 7:19,606,217...19,629,438
Ensembl chr 7:19,606,217...19,629,438
JBrowse link
G Rgs16 regulator of G-protein signaling 16 IAGP MGI PMID:22593615 NCBI chr 1:153,740,353...153,745,468
Ensembl chr 1:153,740,349...153,745,468
JBrowse link
G Rxfp1 relaxin/insulin-like family peptide receptor 1 IAGP MGI PMID:15256493 NCBI chr 3:79,641,600...79,737,951
Ensembl chr 3:79,641,611...79,737,880
JBrowse link
G Sftpd surfactant associated protein D IAGP MGI PMID:10801980 NCBI chr14:41,172,212...41,185,198
Ensembl chr14:41,172,214...41,185,149
JBrowse link
G Spta1 spectrin alpha, erythrocytic 1 IAGP MGI PMID:8355480 NCBI chr 1:174,172,739...174,248,449
Ensembl chr 1:174,172,776...174,248,450
JBrowse link
G Tert telomerase reverse transcriptase IAGP MGI PMID:26555817 NCBI chr13:73,626,911...73,649,843
Ensembl chr13:73,626,911...73,649,843
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II IAGP MGI PMID:27864286 NCBI chr 9:116,087,695...116,175,363
Ensembl chr 9:116,084,293...116,175,360
JBrowse link
G Thy1 thymus cell antigen 1, theta IAGP MGI PMID:16049324 NCBI chr 9:44,043,384...44,048,579
Ensembl chr 9:44,043,384...44,048,579
JBrowse link
G Tmem219 transmembrane protein 219 IAGP MGI PMID:27629921 NCBI chr 7:126,886,219...126,928,821
Ensembl chr 7:126,886,171...126,922,917
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IAGP MGI PMID:9846974 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b IAGP MGI PMID:9846974 NCBI chr 4:145,212,368...145,246,870
Ensembl chr 4:145,213,463...145,246,870
JBrowse link
G Tomm5 translocase of outer mitochondrial membrane 5 IAGP MGI PMID:22688586 NCBI chr 4:45,105,209...45,108,113
Ensembl chr 4:45,105,208...45,108,114
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:23770245 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 IAGP MGI PMID:12665593 NCBI chr17:65,923,065...65,951,187
Ensembl chr17:65,921,972...65,951,226
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 IAGP MGI PMID:19498055 NCBI chr 3:57,455,644...57,575,910
Ensembl chr 3:57,455,649...57,575,910
JBrowse link
pulmonary interstitial fibrosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1, caveolae protein IAGP MGI PMID:11498544 NCBI chr 6:17,306,335...17,341,328
Ensembl chr 6:17,306,335...17,341,452
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator IAGP MGI PMID:9399953 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768
JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 IAGP MGI PMID:15254596 NCBI chr  X:101,731,535...101,734,147
Ensembl chr  X:101,731,535...101,734,269
JBrowse link
G Dkc1 dyskeratosis congenita 1, dyskerin IAGP MGI PMID:12522253 NCBI chr  X:75,095,854...75,109,776
Ensembl chr  X:75,095,854...75,109,777
JBrowse link
G Egr1 early growth response 1 IAGP MGI PMID:19679873 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Plat plasminogen activator, tissue IAGP MGI PMID:10880388 NCBI chr 8:22,757,722...22,782,848
Ensembl chr 8:22,757,727...22,782,844
JBrowse link
G Plau plasminogen activator, urokinase IAGP MGI PMID:10880388 NCBI chr14:20,836,662...20,843,388
Ensembl chr14:20,836,660...20,843,385
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IAGP MGI PMID:11290559 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 14700
    respiratory system phenotype 1610
      abnormal respiratory system morphology 1084
        abnormal lung morphology 729
          pulmonary fibrosis 62
            pulmonary interstitial fibrosis 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.