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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased liver tumor incidence
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Accession:MP:0008019 term browser browse the term
Definition:greater than the expected number of neoplasms in the liver, usually in the form of a distinct mass, in a specific population in a given time period
Synonyms:exact_synonym: increased hepatic tumor incidence;   increased hepatic tumour incidence;   increased liver tumour incidence


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increased liver tumor incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amfr autocrine motility factor receptor IAGP MGI PMID:25789613 NCBI chr 8:93,971,588...94,012,640
Ensembl chr 8:93,971,588...94,012,842
JBrowse link
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:19578404 NCBI chr18:34,220,297...34,322,190
Ensembl chr18:34,220,924...34,322,552
JBrowse link
G Bhmt betaine-homocysteine methyltransferase IAGP MGI PMID:21878621 NCBI chr13:93,616,891...93,637,758
Ensembl chr13:93,616,675...93,637,961
JBrowse link
G Brca1 breast cancer 1, early onset IAGP MGI PMID:19996295, PMID:24120138 NCBI chr11:101,488,761...101,551,955
Ensembl chr11:101,488,764...101,551,955
JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase IAGP MGI PMID:19117986 NCBI chr 2:127,800,197...127,831,859
Ensembl chr 2:127,801,122...127,831,865
JBrowse link
G Cbx7 chromobox 7 IAGP MGI PMID:22214847 NCBI chr15:79,915,804...79,971,143
Ensembl chr15:79,915,807...79,971,119
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A IAGP MGI PMID:17924978 NCBI chr 4:89,274,473...89,294,619
Ensembl chr 4:89,274,471...89,294,653
JBrowse link
G Cers2 ceramide synthase 2 IAGP MGI PMID:19801672 NCBI chr 3:95,314,771...95,323,599
Ensembl chr 3:95,314,791...95,323,599
JBrowse link
G Cul9 cullin 9 IAGP MGI PMID:21487039 NCBI chr17:46,500,609...46,546,388
Ensembl chr17:46,500,572...46,546,388
JBrowse link
G Fah fumarylacetoacetate hydrolase IAGP MGI PMID:7545495 NCBI chr 7:84,585,159...84,605,942
Ensembl chr 7:84,585,159...84,606,722
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) IAGP MGI PMID:19794494 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fen1 flap structure specific endonuclease 1 IAGP MGI PMID:17589521, PMID:24608430 NCBI chr19:10,199,132...10,204,393
Ensembl chr19:10,199,132...10,204,169
JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 IAGP MGI PMID:18552834 NCBI chr10:81,366,879...81,378,370
Ensembl chr10:81,366,222...81,378,516
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19808965 NCBI chr 6:113,067,428...113,077,244
Ensembl chr 6:113,067,428...113,077,333
JBrowse link
G Gtf2ird1 general transcription factor II I repeat domain-containing 1 IAGP MGI PMID:15885355 NCBI chr 5:134,357,661...134,456,867
Ensembl chr 5:134,357,656...134,456,716
JBrowse link
G H19 H19, imprinted maternally expressed transcript IAGP MGI PMID:14681296 NCBI chr 7:142,575,530...142,578,146
Ensembl chr 7:142,575,529...142,578,143
JBrowse link
G Hip1 huntingtin interacting protein 1 IAGP MGI PMID:19647224 NCBI chr 5:135,406,496...135,545,323
Ensembl chr 5:135,406,531...135,545,120
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:27032374 NCBI chr 6:145,216,699...145,250,420
Ensembl chr 6:145,216,699...145,250,239
JBrowse link
G Mfsd1 major facilitator superfamily domain containing 1 IAGP MGI PMID:31661432 NCBI chr 3:67,582,768...67,604,231
Ensembl chr 3:67,582,741...67,604,237
JBrowse link
G Mir122 microRNA 122 IAGP MGI PMID:22820288 NCBI chr18:65,248,861...65,248,926
Ensembl chr18:65,248,861...65,248,926
JBrowse link
G Mob1a MOB kinase activator 1A IAGP MGI PMID:23143302 NCBI chr 6:83,326,034...83,342,812
Ensembl chr 6:83,326,016...83,343,776
JBrowse link
G Mob1b MOB kinase activator 1B IAGP MGI PMID:23143302 NCBI chr 5:88,720,871...88,758,455
Ensembl chr 5:88,720,855...88,764,220
JBrowse link
G Msh2 mutS homolog 2 IAGP MGI PMID:9443401 NCBI chr17:87,672,532...87,723,713
Ensembl chr17:87,672,330...87,723,713
JBrowse link
G Nf2 neurofibromin 2 IAGP MGI PMID:17924978 NCBI chr11:4,757,639...4,849,544
Ensembl chr11:4,765,845...4,849,536
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IAGP MGI PMID:17183066, PMID:17283114 NCBI chr10:89,454,234...89,533,645
Ensembl chr10:89,454,234...89,533,585
JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase IAGP MGI PMID:26443207 NCBI chr15:59,374,198...59,601,689
Ensembl chr15:59,374,247...59,601,684
JBrowse link
G Nudt1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 IAGP MGI PMID:11572992 NCBI chr 5:140,321,622...140,338,137
Ensembl chr 5:140,321,656...140,338,137
JBrowse link
G Pex5 peroxisomal biogenesis factor 5 IAGP MGI PMID:15732085 NCBI chr 6:124,396,816...124,415,944
Ensembl chr 6:124,396,816...124,415,067
JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 IAGP MGI PMID:21436583 NCBI chr14:63,860,277...63,919,862
Ensembl chr14:63,860,364...63,919,859
JBrowse link
G Pkm pyruvate kinase, muscle IAGP MGI PMID:24120138 NCBI chr 9:59,656,576...59,679,372
Ensembl chr 9:59,656,368...59,679,375
JBrowse link
G Plk3 polo like kinase 3 IAGP MGI PMID:18519666 NCBI chr 4:117,128,655...117,133,963
Ensembl chr 4:117,128,655...117,133,963
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:20837017, PMID:27032374 NCBI chr19:32,757,577...32,826,160
Ensembl chr19:32,757,497...32,826,160
JBrowse link
G Rad50 RAD50 double strand break repair protein IAGP MGI PMID:24532689 NCBI chr11:53,649,519...53,707,319
Ensembl chr11:53,649,519...53,707,319
JBrowse link
G Rasal2 RAS protein activator like 2 IAGP MGI PMID:24029233 NCBI chr 1:157,135,183...157,412,595
Ensembl chr 1:157,135,182...157,412,595
JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 IAGP MGI PMID:26980762 NCBI chr 9:107,551,434...107,562,267
Ensembl chr 9:107,551,555...107,562,267
JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:21573126 NCBI chr14:73,192,858...73,325,951
Ensembl chr14:73,183,673...73,325,822
JBrowse link
G Rcbtb2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 IAGP MGI PMID:26291700 NCBI chr14:73,138,745...73,184,055
Ensembl chr14:73,123,037...73,207,843
JBrowse link
G Sav1 salvador family WW domain containing 1 IAGP MGI PMID:20080689, PMID:20404163, PMID:26980762 NCBI chr12:69,965,009...69,988,141
Ensembl chr12:69,965,012...69,987,002
JBrowse link
G Sod1 superoxide dismutase 1, soluble IAGP MGI PMID:25468678 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 IAGP MGI PMID:15732085, PMID:20080689, PMID:20837017, PMID:22820288, PMID:27032374 NCBI chr13:3,149,475...3,189,678
Ensembl chr13:3,149,475...3,189,678
JBrowse link
G Sptbn1 spectrin beta, non-erythrocytic 1 IAGP MGI PMID:20739274 NCBI chr11:30,099,395...30,268,384
Ensembl chr11:30,099,395...30,268,175
JBrowse link
G Stk11 serine/threonine kinase 11 IAGP MGI PMID:16278673 NCBI chr10:80,115,767...80,130,679
Ensembl chr10:80,115,803...80,130,682
JBrowse link
G Stk3 serine/threonine kinase 3 IAGP MGI PMID:20080598, PMID:20080689 NCBI chr15:34,875,499...35,155,882
Ensembl chr15:34,875,496...35,178,921
JBrowse link
G Stk4 serine/threonine kinase 4 IAGP MGI PMID:20080598, PMID:20080689 NCBI chr 2:164,074,113...164,155,524
Ensembl chr 2:164,070,322...164,155,524
JBrowse link
G Trim24 tripartite motif-containing 24 IAGP MGI PMID:18026104 NCBI chr 6:37,870,811...37,968,445
Ensembl chr 6:37,870,811...37,966,296
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:16278673, PMID:20962274, PMID:21436583, PMID:24029233, PMID:24120138 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Tsc1 TSC complex subunit 1 IAGP MGI PMID:26777415 NCBI chr 2:28,640,993...28,691,172
Ensembl chr 2:28,641,228...28,691,167
JBrowse link
G Tspan33 tetraspanin 33 IAGP MGI PMID:17158226 NCBI chr 6:29,694,214...29,718,558
Ensembl chr 6:29,694,222...29,718,559
JBrowse link
G Xpa xeroderma pigmentosum, complementation group A IAGP MGI PMID:11960916 NCBI chr 4:46,175,220...46,196,344
Ensembl chr 4:46,155,347...46,196,311
JBrowse link
increased hepatic hemangioma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo4 F-box protein 4 IAGP MGI PMID:21911473 NCBI chr15:3,963,564...3,979,573
Ensembl chr15:3,965,445...3,979,573
JBrowse link
G Foxo1 forkhead box O1 IAGP MGI PMID:17254969 NCBI chr 3:52,268,337...52,350,109
Ensembl chr 3:52,268,336...52,353,221
JBrowse link
G Foxo3 forkhead box O3 IAGP MGI PMID:17254969 NCBI chr10:42,181,845...42,276,695
Ensembl chr10:42,181,841...42,276,755
JBrowse link
G Foxo4 forkhead box O4 IAGP MGI PMID:17254969 NCBI chr  X:101,254,261...101,260,873
Ensembl chr  X:101,254,528...101,260,873
JBrowse link
G Gnmt glycine N-methyltransferase IAGP MGI PMID:19035462 NCBI chr17:46,725,664...46,729,211
Ensembl chr17:46,725,664...46,729,168
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit IAGP MGI PMID:15798202 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hprt hypoxanthine guanine phosphoribosyl transferase IAGP MGI PMID:15798202 NCBI chr  X:52,988,078...53,021,660
Ensembl chr  X:52,988,137...53,021,659
JBrowse link
G Tsc1 TSC complex subunit 1 IAGP MGI PMID:11438694, PMID:11875047, PMID:15888477 NCBI chr 2:28,640,993...28,691,172
Ensembl chr 2:28,641,228...28,691,167
JBrowse link
G Tsc2 TSC complex subunit 2 IAGP MGI PMID:10096549, PMID:10491404 NCBI chr17:24,595,816...24,632,676
Ensembl chr17:24,595,816...24,632,630
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor IAGP MGI PMID:11171994, PMID:14500363, PMID:15798202 NCBI chr 6:113,623,994...113,631,634
Ensembl chr 6:113,623,959...113,631,633
JBrowse link
increased hepatoblastoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin (cadherin associated protein), beta 1 IAGP MGI PMID:16951686 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Rad50 RAD50 double strand break repair protein IAGP MGI PMID:24532689 NCBI chr11:53,649,519...53,707,319
Ensembl chr11:53,649,519...53,707,319
JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 IAGP MGI PMID:26980762 NCBI chr 9:107,551,434...107,562,267
Ensembl chr 9:107,551,555...107,562,267
JBrowse link
G Sav1 salvador family WW domain containing 1 IAGP MGI PMID:26980762 NCBI chr12:69,965,009...69,988,141
Ensembl chr12:69,965,012...69,987,002
JBrowse link
increased hepatocellular carcinoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 IAGP MGI PMID:7977654, PMID:25478810 NCBI chr 5:8,893,614...8,959,226
Ensembl chr 5:8,893,717...8,959,231
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl IAGP MGI PMID:8798738, PMID:21760938 NCBI chr11:116,171,883...116,199,045
Ensembl chr11:116,171,888...116,199,045
JBrowse link
G Alb albumin IAGP MGI PMID:27032374 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Anxa7 annexin A7 IAGP MGI PMID:14608035 NCBI chr14:20,455,261...20,480,133
Ensembl chr14:20,455,260...20,480,133
JBrowse link
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:8090754, PMID:15563600, PMID:20084116 NCBI chr18:34,220,297...34,322,190
Ensembl chr18:34,220,924...34,322,552
JBrowse link
G Atm ataxia telangiectasia mutated IAGP MGI PMID:24709420 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740
JBrowse link
G Atp11c ATPase, class VI, type 11C IAGP MGI PMID:21423173 NCBI chr  X:60,223,283...60,404,853
Ensembl chr  X:60,223,290...60,592,698
JBrowse link
G Becn1 beclin 1, autophagy related IAGP MGI PMID:14638851, PMID:14657337 NCBI chr11:101,288,258...101,302,286
Ensembl chr11:101,285,952...101,302,286
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 IAGP MGI PMID:16397237 NCBI chr 5:144,190,286...144,194,441
Ensembl chr 5:144,190,286...144,194,441
JBrowse link
G Bhmt betaine-homocysteine methyltransferase IAGP MGI PMID:21878621 NCBI chr13:93,616,891...93,637,758
Ensembl chr13:93,616,675...93,637,961
JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase IAGP MGI PMID:17938250 NCBI chr 2:127,800,197...127,831,859
Ensembl chr 2:127,801,122...127,831,865
JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase IAGP MGI PMID:23878276 NCBI chr 2:118,598,202...118,641,592
Ensembl chr 2:118,598,211...118,641,591
JBrowse link
G Cbx7 chromobox 7 IAGP MGI PMID:22214847 NCBI chr15:79,915,804...79,971,143
Ensembl chr15:79,915,807...79,971,119
JBrowse link
G Ccdc80 coiled-coil domain containing 80 IAGP MGI PMID:25053805 NCBI chr16:45,093,407...45,127,924
Ensembl chr16:45,093,402...45,128,077
JBrowse link
G Ccndbp1 cyclin D-type binding-protein 1 IAGP MGI PMID:17256742 NCBI chr 2:121,008,395...121,016,912
Ensembl chr 2:121,008,403...121,016,904
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) IAGP MGI PMID:14767984, PMID:18598944 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cers2 ceramide synthase 2 IAGP MGI PMID:19801672 NCBI chr 3:95,314,771...95,323,599
Ensembl chr 3:95,314,791...95,323,599
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 IAGP MGI PMID:20084116 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IAGP MGI PMID:25132496 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Eaf2 ELL associated factor 2 IAGP MGI PMID:17873910 NCBI chr16:36,792,884...36,875,068
Ensembl chr16:36,792,884...36,875,003
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 IAGP MGI PMID:19176496 NCBI chr12:84,373,875...84,409,029
Ensembl chr12:84,373,857...84,409,029
JBrowse link
G Fah fumarylacetoacetate hydrolase IAGP MGI PMID:7545495, PMID:18598944 NCBI chr 7:84,585,159...84,605,942
Ensembl chr 7:84,585,159...84,606,722
JBrowse link
G Fbxo4 F-box protein 4 IAGP MGI PMID:21911473 NCBI chr15:3,963,564...3,979,573
Ensembl chr15:3,965,445...3,979,573
JBrowse link
G Fhit fragile histidine triad gene IAGP MGI PMID:15467769 NCBI chr14:9,550,092...11,162,061
Ensembl chr14:9,550,092...11,162,035
JBrowse link
G Foxa1 forkhead box A1 IAGP MGI PMID:22265403 NCBI chr12:57,540,628...57,548,029
Ensembl chr12:57,540,628...57,546,916
JBrowse link
G Foxa2 forkhead box A2 IAGP MGI PMID:22265403 NCBI chr 2:148,042,877...148,046,969
Ensembl chr 2:148,042,877...148,046,969
JBrowse link
G Foxm1 forkhead box M1 IAGP MGI PMID:15082532 NCBI chr 6:128,362,994...128,375,886
Ensembl chr 6:128,362,967...128,376,146
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IAGP MGI PMID:25448926 NCBI chr17:24,693,190...24,696,156
Ensembl chr17:24,693,187...24,696,156
JBrowse link
G Gnmt glycine N-methyltransferase IAGP MGI PMID:19035462 NCBI chr17:46,725,664...46,729,211
Ensembl chr17:46,725,664...46,729,168
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19234449, PMID:19808965, PMID:23408915 NCBI chr 6:113,067,428...113,077,244
Ensembl chr 6:113,067,428...113,077,333
JBrowse link
G Gtf2ird1 general transcription factor II I repeat domain-containing 1 IAGP MGI PMID:8467484, PMID:8701981, PMID:15885355 NCBI chr 5:134,357,661...134,456,867
Ensembl chr 5:134,357,656...134,456,716
JBrowse link
G Hic1 hypermethylated in cancer 1 IAGP MGI PMID:12539045 NCBI chr11:75,161,377...75,170,255
Ensembl chr11:75,164,565...75,169,519
JBrowse link
G Hip1 huntingtin interacting protein 1 IAGP MGI PMID:19647224 NCBI chr 5:135,406,496...135,545,323
Ensembl chr 5:135,406,531...135,545,120
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 IAGP MGI PMID:14695192 NCBI chr 7:49,759,045...49,774,000
Ensembl chr 7:49,759,115...49,773,975
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma IAGP MGI PMID:17292824, PMID:19635861, PMID:20478530 NCBI chr  X:74,393,233...74,456,792
Ensembl chr  X:74,393,290...74,453,854
JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:24332041 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 IAGP MGI PMID:18180285 NCBI chr 7:80,711,583...80,815,549
Ensembl chr 7:80,711,583...80,825,974
JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 IAGP MGI PMID:18180285, PMID:23951254 NCBI chr13:95,627,177...95,892,280
Ensembl chr13:95,627,174...95,892,483
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:20643348, PMID:27032374 NCBI chr 6:145,216,699...145,250,420
Ensembl chr 6:145,216,699...145,250,239
JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 IAGP MGI PMID:22251704 NCBI chr13:56,529,734...56,548,559
Ensembl chr13:56,542,464...56,548,502
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 IAGP MGI PMID:18637146 NCBI chr14:47,373,860...47,386,167
Ensembl chr14:47,367,751...47,386,160
JBrowse link
G Lzts1 leucine zipper, putative tumor suppressor 1 IAGP MGI PMID:17349584 NCBI chr 8:69,132,659...69,184,249
Ensembl chr 8:69,132,669...69,184,225
JBrowse link
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 IAGP MGI PMID:17210695 NCBI chr 5:140,008,689...140,321,608
Ensembl chr 5:140,008,689...140,321,552
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 IAGP MGI PMID:20478530 NCBI chr 4:31,963,492...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Mc4r melanocortin 4 receptor IAGP MGI PMID:21906580 NCBI chr18:66,857,705...66,860,487
Ensembl chr18:66,857,704...66,860,506
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 IAGP MGI PMID:17143284 NCBI chr16:15,623,897...15,637,400
Ensembl chr16:15,623,897...15,637,400
JBrowse link
G Mcm9 minichromosome maintenance 9 homologous recombination repair factor IAGP MGI PMID:21987787 NCBI chr10:53,536,315...53,630,006
Ensembl chr10:53,536,315...53,630,439
JBrowse link
G Mir122 microRNA 122 IAGP MGI PMID:22820288, PMID:22820290 NCBI chr18:65,248,861...65,248,926
Ensembl chr18:65,248,861...65,248,926
JBrowse link
G Mob1a MOB kinase activator 1A IAGP MGI PMID:26699479 NCBI chr 6:83,326,034...83,342,812
Ensembl chr 6:83,326,016...83,343,776
JBrowse link
G Mob1b MOB kinase activator 1B IAGP MGI PMID:26699479 NCBI chr 5:88,720,871...88,758,455
Ensembl chr 5:88,720,855...88,764,220
JBrowse link
G Mzf1 myeloid zinc finger 1 IAGP MGI PMID:11445537 NCBI chr 7:13,042,303...13,054,764
Ensembl chr 7:13,042,303...13,054,764
JBrowse link
G Nabp2 nucleic acid binding protein 2 IAGP MGI PMID:23408915 NCBI chr10:128,401,394...128,411,548
Ensembl chr10:128,401,395...128,411,492
JBrowse link
G Ncoa5 nuclear receptor coactivator 5 IAGP MGI PMID:24332041 NCBI chr 2:165,000,353...165,034,871
Ensembl chr 2:165,000,357...165,034,867
JBrowse link
G Ndrg2 N-myc downstream regulated gene 2 IAGP MGI PMID:24569712 NCBI chr14:51,905,271...51,914,004
Ensembl chr14:51,905,271...51,914,158
JBrowse link
G Nf1 neurofibromin 1 IAGP MGI PMID:25119042 NCBI chr11:79,339,590...79,581,609
Ensembl chr11:79,339,693...79,581,612
JBrowse link
G Nf2 neurofibromin 2 IAGP MGI PMID:20643348 NCBI chr11:4,757,639...4,849,544
Ensembl chr11:4,765,845...4,849,536
JBrowse link
G Nfe2l1 nuclear factor, erythroid derived 2,-like 1 IAGP MGI PMID:15738389 NCBI chr11:96,817,414...96,829,968
Ensembl chr11:96,817,414...96,829,968
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IAGP MGI PMID:17183066, PMID:17283114 NCBI chr10:89,454,234...89,533,645
Ensembl chr10:89,454,234...89,533,585
JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 IAGP MGI PMID:21436583 NCBI chr14:63,860,277...63,919,862
Ensembl chr14:63,860,364...63,919,859
JBrowse link
G Prdx1 peroxiredoxin 1 IAGP MGI PMID:12891360 NCBI chr 4:116,685,599...116,700,000
Ensembl chr 4:116,685,544...116,700,822
JBrowse link
G Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha IAGP MGI PMID:15371594 NCBI chr11:109,649,023...109,669,663
Ensembl chr11:109,649,405...109,669,656
JBrowse link
G Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) IAGP MGI PMID:11782352 NCBI chr17:34,182,030...34,187,330
Ensembl chr17:34,181,987...34,187,764
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:15199412, PMID:16767220, PMID:17567478, PMID:19011632, PMID:20837017, PMID:27032374 NCBI chr19:32,757,577...32,826,160
Ensembl chr19:32,757,497...32,826,160
JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:16751807 NCBI chr 2:101,638,252...101,649,532
Ensembl chr 2:101,638,282...101,649,501
JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:26753883 NCBI chr 2:101,624,712...101,632,528
Ensembl chr 2:101,624,718...101,632,529
JBrowse link
G Ranbp2 RAN binding protein 2 IAGP MGI PMID:18394993 NCBI chr10:58,446,852...58,494,155
Ensembl chr10:58,446,920...58,494,356
JBrowse link
G Rasal2 RAS protein activator like 2 IAGP MGI PMID:24029233 NCBI chr 1:157,135,183...157,412,595
Ensembl chr 1:157,135,182...157,412,595
JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 IAGP MGI PMID:26980762 NCBI chr 9:107,551,434...107,562,267
Ensembl chr 9:107,551,555...107,562,267
JBrowse link
G Rassf5 Ras association (RalGDS/AF-6) domain family member 5 IAGP MGI PMID:21194982 NCBI chr 1:131,176,410...131,245,178
Ensembl chr 1:131,176,410...131,245,258
JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:21573126, PMID:21875955 NCBI chr14:73,192,858...73,325,951
Ensembl chr14:73,183,673...73,325,822
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 IAGP MGI PMID:21875955 NCBI chr 2:157,145,893...157,204,534
Ensembl chr 2:157,145,893...157,204,534
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 IAGP MGI PMID:21875955 NCBI chr 8:91,070,057...91,123,844
Ensembl chr 8:91,070,057...91,123,844
JBrowse link
G Rint1 RAD50 interactor 1 IAGP MGI PMID:17470549 NCBI chr 5:23,787,698...23,823,584
Ensembl chr 5:23,787,711...23,820,369
JBrowse link
G S100a4 S100 calcium binding protein A4 IAGP MGI PMID:15116098 NCBI chr 3:90,603,770...90,606,045
Ensembl chr 3:90,603,771...90,606,045
JBrowse link
G Sav1 salvador family WW domain containing 1 IAGP MGI PMID:20080689, PMID:26131558, PMID:26980762 NCBI chr12:69,965,009...69,988,141
Ensembl chr12:69,965,012...69,987,002
JBrowse link
G Sirt2 sirtuin 2 IAGP MGI PMID:22014574 NCBI chr 7:28,766,752...28,788,665
Ensembl chr 7:28,766,735...28,788,661
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 IAGP MGI PMID:22552287 NCBI chr11:106,820,061...106,920,747
Ensembl chr11:106,820,066...106,920,715
JBrowse link
G Sod1 superoxide dismutase 1, soluble IAGP MGI PMID:25468678 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 IAGP MGI PMID:15199412, PMID:15738389, PMID:17567478, PMID:19234449, PMID:19878874, PMID:20080689, PMID:20643348, PMID:20837017, PMID:22820288, PMID:25132496, PMID:25448926, PMID:26131558, PMID:26699479, PMID:27032374 NCBI chr13:3,149,475...3,189,678
Ensembl chr13:3,149,475...3,189,678
JBrowse link
G Sptbn1 spectrin beta, non-erythrocytic 1 IAGP MGI PMID:18263735, PMID:20739274 NCBI chr11:30,099,395...30,268,384
Ensembl chr11:30,099,395...30,268,175
JBrowse link
G Stag1 stromal antigen 1 IAGP MGI PMID:22415365 NCBI chr 9:100,597,709...100,958,544
Ensembl chr 9:100,597,798...100,959,375
JBrowse link
G Stk11 serine/threonine kinase 11 IAGP MGI PMID:11956081, PMID:12218179, PMID:16278673 NCBI chr10:80,115,767...80,130,679
Ensembl chr10:80,115,803...80,130,682
JBrowse link
G Stk3 serine/threonine kinase 3 IAGP MGI PMID:19878874, PMID:20080598, PMID:20080689, PMID:26131558 NCBI chr15:34,875,499...35,155,882
Ensembl chr15:34,875,496...35,178,921
JBrowse link
G Stk4 serine/threonine kinase 4 IAGP MGI PMID:19878874, PMID:20080598, PMID:20080689, PMID:26131558 NCBI chr 2:164,074,113...164,155,524
Ensembl chr 2:164,070,322...164,155,524
JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit IAGP MGI PMID:25119042 NCBI chr11:79,993,106...80,034,123
Ensembl chr11:79,993,106...80,034,123
JBrowse link
G Tnk1 tyrosine kinase, non-receptor, 1 IAGP MGI PMID:18974114 NCBI chr11:69,850,563...69,858,730
Ensembl chr11:69,851,005...69,858,730
JBrowse link
G Tpx2 TPX2, microtubule-associated IAGP MGI PMID:22266221 NCBI chr 2:152,847,964...152,895,321
Ensembl chr 2:152,847,964...152,895,321
JBrowse link
G Trim24 tripartite motif-containing 24 IAGP MGI PMID:18026104 NCBI chr 6:37,870,811...37,968,445
Ensembl chr 6:37,870,811...37,966,296
JBrowse link
G Trim62 tripartite motif-containing 62 IAGP MGI PMID:23838884 NCBI chr 4:128,884,044...128,911,326
Ensembl chr 4:128,883,580...128,911,328
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:15607980, PMID:15837625, PMID:16278673, PMID:16397237, PMID:16751807, PMID:19234449, PMID:21436583, PMID:24029233, PMID:25453901 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Trp73 transformation related protein 73 IAGP MGI PMID:15837625 NCBI chr 4:154,056,249...154,139,875
Ensembl chr 4:154,056,253...154,140,208
Ensembl chr 4:154,056,253...154,140,208
JBrowse link
G Txnip thioredoxin interacting protein IAGP MGI PMID:16607285 NCBI chr 3:96,557,957...96,561,857
Ensembl chr 3:96,557,957...96,561,883
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats IAGP MGI PMID:19637241 NCBI chr 9:60,793,206...60,880,431
Ensembl chr 9:60,794,542...60,880,370
JBrowse link
G Urah urate (5-hydroxyiso-) hydrolase IAGP MGI PMID:20823251 NCBI chr 7:140,834,958...140,837,971
Ensembl chr 7:140,835,018...140,837,966
JBrowse link
G Yap1 yes-associated protein 1 IAGP MGI PMID:20643348 NCBI chr 9:7,931,999...8,004,638
Ensembl chr 9:7,931,999...8,004,596
JBrowse link
increased hepatoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl IAGP MGI PMID:9624157 NCBI chr11:116,171,883...116,199,045
Ensembl chr11:116,171,888...116,199,045
JBrowse link
G Ahr aryl-hydrocarbon receptor IAGP MGI PMID:9396142 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038
JBrowse link
G Aurka aurora kinase A IAGP MGI PMID:18801727 NCBI chr 2:172,356,190...172,370,886
Ensembl chr 2:172,356,190...172,370,535
JBrowse link
G Brca1 breast cancer 1, early onset IAGP MGI PMID:15485917 NCBI chr11:101,488,761...101,551,955
Ensembl chr11:101,488,764...101,551,955
JBrowse link
G Cat catalase IEA MGI NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccng1 cyclin G1 IAGP MGI PMID:12668979 NCBI chr11:40,748,552...40,755,309
Ensembl chr11:40,748,552...40,755,311
JBrowse link
G Cdc20 cell division cycle 20 IAGP MGI PMID:19528295 NCBI chr 4:118,432,901...118,437,343
Ensembl chr 4:118,432,901...118,437,352
JBrowse link
G Dna2 DNA replication helicase/nuclease 2 IAGP MGI PMID:23604072 NCBI chr10:62,946,983...62,974,188
Ensembl chr10:62,947,026...62,974,185
JBrowse link
G Fah fumarylacetoacetate hydrolase IAGP MGI PMID:7545495 NCBI chr 7:84,585,159...84,605,942
Ensembl chr 7:84,585,159...84,606,722
JBrowse link
G Fancm Fanconi anemia, complementation group M IAGP MGI PMID:19561169 NCBI chr12:65,074,110...65,131,842
Ensembl chr12:65,075,603...65,132,058
JBrowse link
G Nf1 neurofibromin 1 IAGP MGI PMID:7920653 NCBI chr11:79,339,590...79,581,609
Ensembl chr11:79,339,693...79,581,612
JBrowse link
G Rbm38 RNA binding motif protein 38 IAGP MGI PMID:25512531 NCBI chr 2:173,021,891...173,034,734
Ensembl chr 2:173,020,498...173,034,734
JBrowse link
G Sav1 salvador family WW domain containing 1 IAGP MGI PMID:20404163 NCBI chr12:69,965,009...69,988,141
Ensembl chr12:69,965,012...69,987,002
JBrowse link
G Socs1 suppressor of cytokine signaling 1 IAGP MGI PMID:15197228 NCBI chr16:10,783,808...10,785,536
Ensembl chr16:10,782,240...10,785,536
JBrowse link
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 IAGP MGI PMID:20404163 NCBI chr13:3,149,475...3,189,678
Ensembl chr13:3,149,475...3,189,678
JBrowse link
G Srpx sushi-repeat-containing protein IAGP MGI PMID:17088259 NCBI chr  X:10,037,977...10,117,640
Ensembl chr  X:10,037,977...10,117,709
JBrowse link
G Tnk1 tyrosine kinase, non-receptor, 1 IAGP MGI PMID:18974114 NCBI chr11:69,850,563...69,858,730
Ensembl chr11:69,851,005...69,858,730
JBrowse link
G Usp44 ubiquitin specific peptidase 44 IAGP MGI PMID:23187126 NCBI chr10:93,819,969...93,859,425
Ensembl chr10:93,831,555...93,858,088
JBrowse link
increased liver adenocarcinoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 IAGP MGI PMID:21901109 NCBI chr11:80,089,379...80,135,797
Ensembl chr11:80,089,400...80,135,794
JBrowse link
G Aurkb aurora kinase B IAGP MGI PMID:21613325 NCBI chr11:69,045,624...69,051,664
Ensembl chr11:69,045,647...69,051,664
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 IAGP MGI PMID:20832750 NCBI chr10:117,688,875...117,710,758
Ensembl chr10:117,688,875...117,710,758
JBrowse link
G Nbn nibrin IAGP MGI PMID:14612522 NCBI chr 4:15,957,587...15,992,589
Ensembl chr 4:15,957,925...15,992,589
JBrowse link
G Thbs1 thrombospondin 1 IAGP MGI PMID:11696456 NCBI chr 2:118,111,876...118,127,133
Ensembl chr 2:118,111,876...118,127,133
JBrowse link
G Trim62 tripartite motif-containing 62 IAGP MGI PMID:23838884 NCBI chr 4:128,884,044...128,911,326
Ensembl chr 4:128,883,580...128,911,328
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:11696456, PMID:20832750 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
increased liver adenoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl-hydrocarbon receptor IAGP MGI PMID:9396142 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038
JBrowse link
G Alb albumin IAGP MGI PMID:21109326 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 IAGP MGI PMID:16397237 NCBI chr 5:144,190,286...144,194,441
Ensembl chr 5:144,190,286...144,194,441
JBrowse link
G Bhmt betaine-homocysteine methyltransferase IAGP MGI PMID:21878621 NCBI chr13:93,616,891...93,637,758
Ensembl chr13:93,616,675...93,637,961
JBrowse link
G Cbx7 chromobox 7 IAGP MGI PMID:22214847 NCBI chr15:79,915,804...79,971,143
Ensembl chr15:79,915,807...79,971,119
JBrowse link
G Ccndbp1 cyclin D-type binding-protein 1 IAGP MGI PMID:17256742 NCBI chr 2:121,008,395...121,016,912
Ensembl chr 2:121,008,403...121,016,904
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 IAGP MGI PMID:19176496 NCBI chr12:84,373,875...84,409,029
Ensembl chr12:84,373,857...84,409,029
JBrowse link
G Fah fumarylacetoacetate hydrolase IAGP MGI PMID:7545495 NCBI chr 7:84,585,159...84,605,942
Ensembl chr 7:84,585,159...84,606,722
JBrowse link
G G6pc glucose-6-phosphatase, catalytic IAGP MGI PMID:21109326 NCBI chr11:101,367,716...101,377,903
Ensembl chr11:101,367,561...101,377,903
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19234449, PMID:19808965 NCBI chr 6:113,067,428...113,077,244
Ensembl chr 6:113,067,428...113,077,333
JBrowse link
G Gtf2ird1 general transcription factor II I repeat domain-containing 1 IAGP MGI PMID:8701981 NCBI chr 5:134,357,661...134,456,867
Ensembl chr 5:134,357,656...134,456,716
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 IAGP MGI PMID:20832750 NCBI chr10:117,688,875...117,710,758
Ensembl chr10:117,688,875...117,710,758
JBrowse link
G Mob1a MOB kinase activator 1A IAGP MGI PMID:26699479 NCBI chr 6:83,326,034...83,342,812
Ensembl chr 6:83,326,016...83,343,776
JBrowse link
G Mob1b MOB kinase activator 1B IAGP MGI PMID:26699479 NCBI chr 5:88,720,871...88,758,455
Ensembl chr 5:88,720,855...88,764,220
JBrowse link
G Msh2 mutS homolog 2 IAGP MGI PMID:10992298 NCBI chr17:87,672,532...87,723,713
Ensembl chr17:87,672,330...87,723,713
JBrowse link
G Nbn nibrin IAGP MGI PMID:14612522 NCBI chr 4:15,957,587...15,992,589
Ensembl chr 4:15,957,925...15,992,589
JBrowse link
G Nfe2l1 nuclear factor, erythroid derived 2,-like 1 IAGP MGI PMID:15738389 NCBI chr11:96,817,414...96,829,968
Ensembl chr11:96,817,414...96,829,968
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IAGP MGI PMID:17183066, PMID:17283114 NCBI chr10:89,454,234...89,533,645
Ensembl chr10:89,454,234...89,533,585
JBrowse link
G Pex1 peroxisomal biogenesis factor 1 IAGP MGI PMID:31207289 NCBI chr 5:3,596,066...3,637,230
Ensembl chr 5:3,596,066...3,637,232
JBrowse link
G Pms2 PMS1 homolog2, mismatch repair system component IAGP MGI PMID:20624957 NCBI chr 5:143,909,901...143,972,745
Ensembl chr 5:143,909,964...143,933,968
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:9990064, PMID:15199412, PMID:17567478 NCBI chr19:32,757,577...32,826,160
Ensembl chr19:32,757,497...32,826,160
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 IAGP MGI PMID:21575863 NCBI chr 5:121,130,533...121,191,397
Ensembl chr 5:121,130,533...121,191,397
JBrowse link
G Rad50 RAD50 double strand break repair protein IAGP MGI PMID:24532689 NCBI chr11:53,649,519...53,707,319
Ensembl chr11:53,649,519...53,707,319
JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 IAGP MGI PMID:26980762 NCBI chr 9:107,551,434...107,562,267
Ensembl chr 9:107,551,555...107,562,267
JBrowse link
G Sav1 salvador family WW domain containing 1 IAGP MGI PMID:26980762 NCBI chr12:69,965,009...69,988,141
Ensembl chr12:69,965,012...69,987,002
JBrowse link
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 IAGP MGI PMID:15199412, PMID:15738389, PMID:17567478, PMID:19234449, PMID:21575863, PMID:26699479 NCBI chr13:3,149,475...3,189,678
Ensembl chr13:3,149,475...3,189,678
JBrowse link
G Stk11 serine/threonine kinase 11 IAGP MGI PMID:12218179 NCBI chr10:80,115,767...80,130,679
Ensembl chr10:80,115,803...80,130,682
JBrowse link
G Trim24 tripartite motif-containing 24 IAGP MGI PMID:18026104 NCBI chr 6:37,870,811...37,968,445
Ensembl chr 6:37,870,811...37,966,296
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:19234449, PMID:20832750 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Xpa xeroderma pigmentosum, complementation group A IAGP MGI PMID:11960916 NCBI chr 4:46,175,220...46,196,344
Ensembl chr 4:46,155,347...46,196,311
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 14897
    liver/biliary system phenotype 1623
      abnormal hepatobiliary system morphology 1461
        increased hepatobiliary system tumor incidence 156
          increased liver tumor incidence 153
            increased hepatic hemangioma incidence 10
            increased hepatoblastoma incidence 4
            increased hepatocellular carcinoma incidence 95
            increased hepatoma incidence 29
            increased liver adenocarcinoma incidence 7
            increased liver adenoma incidence 30
Path 2
Term Annotations click to browse term
  mammalian phenotype 14897
    neoplasm 1237
      altered tumor susceptibility 1108
        abnormal tumor incidence 1090
          increased tumor incidence 932
            increased organ/body region tumor incidence 795
              increased hepatobiliary system tumor incidence 156
                increased liver tumor incidence 153
                  increased hepatic hemangioma incidence 10
                  increased hepatoblastoma incidence 4
                  increased hepatocellular carcinoma incidence 95
                  increased hepatoma incidence 29
                  increased liver adenocarcinoma incidence 7
                  increased liver adenoma incidence 30
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.