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ONTOLOGY REPORT - ANNOTATIONS


Term:decreased NK T cell number
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Accession:MP:0008040 term browser browse the term
Definition:reduced number of the distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments
Synonyms:exact_synonym: decreased NK T lymphocyte number;   decreased NKT cell number;   decreased natural T cell number;   decreased natural killer T cell number;   decreased natural killer T lymphocyte number;   reduced NK T cell number;   reduced NK T lymphocyte number;   reduced NKT cell number;   reduced natural T cell number;   reduced natural killer T cell number;   reduced natural killer T lymphocyte number


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decreased NK T cell number term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G 1700016L21Rik RIKEN cDNA 1700016L21 gene JBrowse link 1 80,445,932 80,475,660 RGD:5509061
G Apc APC, WNT signaling pathway regulator JBrowse link 18 34,220,297 34,322,190 RGD:5509061
G Atf2 activating transcription factor 2 JBrowse link 2 73,816,509 73,892,677 RGD:5509061
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) JBrowse link 2 128,126,038 128,162,547 RGD:5509061
G Card11 caspase recruitment domain family, member 11 JBrowse link 5 140,872,999 141,000,596 RGD:5509061
G Cd1d1 CD1d1 antigen JBrowse link 3 86,995,834 87,012,358 RGD:5509061
G Cd247 CD247 antigen JBrowse link 1 165,779,952 165,871,153 RGD:5509061
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit JBrowse link 17 56,990,264 56,996,371 RGD:5509061
G Cog6 component of oligomeric golgi complex 6 JBrowse link 3 52,982,123 53,017,223 RGD:5509061
G Cxcl16 chemokine (C-X-C motif) ligand 16 JBrowse link 11 70,454,389 70,459,984 RGD:5509061
G Dclre1c DNA cross-link repair 1C JBrowse link 2 3,424,061 3,474,211 RGD:5509061
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 11 70,017,203 70,045,535 RGD:5509061
G Dph6 diphthamine biosynthesis 6 JBrowse link 2 114,516,416 114,655,046 RGD:5509061
G Duoxa2 dual oxidase maturation factor 2 JBrowse link 2 122,298,900 122,302,885 RGD:5509061
G Elf4 E74-like factor 4 (ets domain transcription factor) JBrowse link X 48,411,049 48,463,132 RGD:5509061
G Eomes eomesodermin JBrowse link 9 118,478,186 118,486,132 RGD:5509061
G Ezr ezrin JBrowse link 17 6,738,131 6,782,780 RGD:5509061
G Fbxo7 F-box protein 7 JBrowse link 10 86,020,449 86,051,873 RGD:5509061
G Gimap5 GTPase, IMAP family member 5 JBrowse link 6 48,746,197 48,754,200 RGD:5509061
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano JBrowse link 6 113,067,428 113,077,244 RGD:5509061
G Ikbkg inhibitor of kappaB kinase gamma JBrowse link X 74,393,233 74,456,792 RGD:5509061
G Il15 interleukin 15 JBrowse link 8 82,331,624 82,403,252 RGD:5509061
G Il15ra interleukin 15 receptor, alpha chain JBrowse link 2 11,705,172 11,733,985 RGD:5509061
G Il17rb interleukin 17 receptor B JBrowse link 14 29,996,168 30,008,896 RGD:5509061
G Il2rb interleukin 2 receptor, beta chain JBrowse link 15 78,479,256 78,511,621 RGD:5509061
G Il2rg interleukin 2 receptor, gamma chain JBrowse link X 101,264,385 101,268,255 RGD:5509061
G Il7 interleukin 7 JBrowse link 3 7,572,028 7,613,760 RGD:5509061
G Il7r interleukin 7 receptor JBrowse link 15 9,506,159 9,529,941 RGD:5509061
G Isg20 interferon-stimulated protein JBrowse link 7 78,913,396 78,920,396 RGD:5509061
G Itk IL2 inducible T cell kinase JBrowse link 11 46,325,148 46,389,515 RGD:5509061
G Jak3 Janus kinase 3 JBrowse link 8 71,676,383 71,690,577 RGD:5509061
G Kmt2e lysine (K)-specific methyltransferase 2E JBrowse link 5 23,433,036 23,504,235 RGD:5509061
G Lcp2 lymphocyte cytosolic protein 2 JBrowse link 11 34,046,928 34,092,281 RGD:5509061
G Lyplal1 lysophospholipase-like 1 JBrowse link 1 186,087,732 186,117,310 RGD:5509061
G Map3k14 mitogen-activated protein kinase kinase kinase 14 JBrowse link 11 103,219,764 103,267,401 RGD:5509061
G Map3k7 mitogen-activated protein kinase kinase kinase 7 JBrowse link 4 31,963,492 32,023,470 RGD:5509061
G Ncf2 neutrophil cytosolic factor 2 JBrowse link 1 152,800,153 152,836,990 RGD:5509061
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:5509061
G Nhej1 non-homologous end joining factor 1 JBrowse link 1 74,967,346 75,125,226 RGD:5509061
G Ninj2 ninjurin 2 JBrowse link 6 120,093,380 120,200,531 RGD:5509061
G Pcsk1 proprotein convertase subtilisin/kexin type 1 JBrowse link 13 75,089,420 75,134,861 RGD:5509061
G Pdpk1 3-phosphoinositide dependent protein kinase 1 JBrowse link 17 24,073,680 24,155,619 RGD:5509061
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 13 101,680,761 101,768,217 RGD:5509061
G Prkcq protein kinase C, theta JBrowse link 2 11,171,905 11,301,226 RGD:5509061
G Prkdc protein kinase, DNA activated, catalytic polypeptide JBrowse link 16 15,637,444 15,842,239 RGD:5509061
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:5509061
G Rag2 recombination activating gene 2 JBrowse link 2 101,624,712 101,632,528 RGD:5509061
G Rasal3 RAS protein activator like 3 JBrowse link 17 32,390,659 32,403,599 RGD:5509061
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B JBrowse link 7 19,606,217 19,629,438 RGD:5509061
G Sgms1 sphingomyelin synthase 1 JBrowse link 19 32,122,727 32,389,885 RGD:5509061
G Sh2d1a SH2 domain containing 1A JBrowse link X 42,502,565 42,522,097 RGD:5509061
G Sik3 SIK family kinase 3 JBrowse link 9 46,012,820 46,224,194 RGD:5509061
G Slc25a21 solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 JBrowse link 12 56,712,634 57,197,472 RGD:5509061
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 JBrowse link 13 3,149,475 3,189,678 RGD:5509061
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) JBrowse link 17 34,204,479 34,216,321 RGD:5509061
G Tbk1 TANK-binding kinase 1 JBrowse link 10 121,546,455 121,586,794 RGD:5509061
G Tbx21 T-box 21 JBrowse link 11 97,098,007 97,115,331 RGD:5509061
G Tcf3 transcription factor 3 JBrowse link 10 80,409,165 80,433,976 RGD:5509061
G Tcra T cell receptor alpha chain JBrowse link 14 52,427,967 54,224,198 RGD:5509061
G Tox thymocyte selection-associated high mobility group box JBrowse link 4 6,686,353 6,991,552 RGD:5509061
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:5509061
G Txnip thioredoxin interacting protein JBrowse link 3 96,557,957 96,561,857 RGD:5509061
G Vav1 vav 1 oncogene JBrowse link 17 57,279,100 57,329,236 RGD:5509061
G Zfp335 zinc finger protein 335 JBrowse link 2 164,891,882 164,912,585 RGD:5509061
G Zfp683 zinc finger protein 683 JBrowse link 4 134,051,195 134,058,941 RGD:5509061
absent NK T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il2rg interleukin 2 receptor, gamma chain JBrowse link X 101,264,385 101,268,255 RGD:5509061
G Kdelr1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 JBrowse link 7 45,872,840 45,883,726 RGD:5509061
G Lyst lysosomal trafficking regulator JBrowse link 13 13,590,311 13,778,803 RGD:5509061
G Pdpk1 3-phosphoinositide dependent protein kinase 1 JBrowse link 17 24,073,680 24,155,619 RGD:5509061
G Rag1 recombination activating 1 JBrowse link 2 101,638,252 101,649,532 RGD:5509061
G Sh2d1a SH2 domain containing 1A JBrowse link X 42,502,565 42,522,097 RGD:5509061
G Tbx21 T-box 21 JBrowse link 11 97,098,007 97,115,331 RGD:5509061
G Traj18 T cell receptor alpha joining 18 JBrowse link 14 54,200,777 54,200,842 RGD:5509061
decreased CD4-positive NK T cell number term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit JBrowse link 17 56,990,264 56,996,371 RGD:5509061
G Cog6 component of oligomeric golgi complex 6 JBrowse link 3 52,982,123 53,017,223 RGD:5509061
G Gmds GDP-mannose 4, 6-dehydratase JBrowse link 13 31,819,583 32,338,762 RGD:5509061
G Sik3 SIK family kinase 3 JBrowse link 9 46,012,820 46,224,194 RGD:5509061
decreased Ly6C-positive NK T cell number term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pepd peptidase D JBrowse link 7 34,912,407 35,044,708 RGD:5509061
decreased memory-marker CD4-negative NK T cell number term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit JBrowse link 17 56,990,264 56,996,371 RGD:5509061
G Cog6 component of oligomeric golgi complex 6 JBrowse link 3 52,982,123 53,017,223 RGD:5509061
G Gmds GDP-mannose 4, 6-dehydratase JBrowse link 13 31,819,583 32,338,762 RGD:5509061
G Hbs1l Hbs1-like (S. cerevisiae) JBrowse link 10 21,295,979 21,368,889 RGD:5509061
G Sik3 SIK family kinase 3 JBrowse link 9 46,012,820 46,224,194 RGD:5509061
decreased memory-marker CD4-positive NK T cell number term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 JBrowse link 7 24,902,986 24,926,594 RGD:5509061
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit JBrowse link 17 56,990,264 56,996,371 RGD:5509061
G Cog6 component of oligomeric golgi complex 6 JBrowse link 3 52,982,123 53,017,223 RGD:5509061
G Gmds GDP-mannose 4, 6-dehydratase JBrowse link 13 31,819,583 32,338,762 RGD:5509061
G Sik3 SIK family kinase 3 JBrowse link 9 46,012,820 46,224,194 RGD:5509061

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 13565
    hematopoietic system phenotype 3730
      abnormal hematopoietic system morphology/development 3284
        abnormal hematopoietic cell morphology 2854
          abnormal leukocyte morphology 2116
            abnormal leukocyte cell number 1871
              abnormal lymphocyte cell number 1355
                abnormal T cell number 929
                  decreased T cell number 695
                    decreased NK T cell number 74
                      absent NK T cells 8
                      decreased CD4-negative NK T cell number + 5
                      decreased CD4-positive NK T cell number + 5
                      decreased Ly6C-positive NK T cell number 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 13565
    immune system phenotype 4164
      abnormal immune system morphology 2735
        abnormal immune system cell morphology 2136
          abnormal leukocyte morphology 2116
            abnormal mononuclear cell morphology 1805
              abnormal lymphocyte morphology 1478
                abnormal T cell morphology 1019
                  abnormal alpha-beta T cell morphology 789
                    abnormal NK T cell morphology 104
                      abnormal NK T cell number 104
                        decreased NK T cell number 74
                          absent NK T cells 8
                          decreased CD4-negative NK T cell number + 5
                          decreased CD4-positive NK T cell number + 5
                          decreased Ly6C-positive NK T cell number 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.