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ONTOLOGY REPORT - ANNOTATIONS


Term:increased CD8-positive, alpha-beta T cell number
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Accession:MP:0008078 term browser browse the term
Definition:greater number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions
Comment:Generally, when immunologists write CD8 positive T cell, what they mean is CD8-positive, alpha-beta T cell (CL:0000625). Similarly, when immunologists write CD4 positive T cell, what they mean is CD4-positive, alpha-beta T cell (CL:0000624). T cells bearing the alpha-beta T cell receptor are the most common in the body, and are the most commonly studied, so much so, that in many published papers, the authors do not even bother to specify (or assume) they are studying alpha-beta T cells and thus omit saying so.
Synonyms:exact_synonym: increased CD8+ T cell number;   increased CD8-positive T cell number


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increased CD8-positive, alpha-beta T cell number term browser
Symbol Object Name JBrowse Chr Start Stop Reference
S DA DA RGD:61088

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5003
    immune system phenotype 400
      abnormal immune system morphology 111
        abnormal immune system cell morphology 88
          abnormal leukocyte morphology 87
            abnormal leukocyte cell number 77
              abnormal lymphocyte cell number 60
                abnormal T cell number 44
                  abnormal alpha-beta T cell number 6
                    abnormal CD8-positive, alpha-beta T cell number 6
                      increased CD8-positive, alpha-beta T cell number 1
                        increased CD8-positive, CD25-positive alpha-beta T cell number 0
                        increased CD8-positive, alpha-beta memory T cell number + 0
                        increased KLRG1+ CD8 alpha beta T cell number 0
                        increased Tc17 cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5003
    immune system phenotype 400
      abnormal immune system morphology 111
        abnormal immune system cell morphology 88
          abnormal leukocyte morphology 87
            abnormal mononuclear cell morphology 70
              abnormal lymphocyte morphology 66
                abnormal T cell morphology 49
                  abnormal effector T cell morphology 10
                    abnormal CD8-positive, alpha beta T cell morphology 8
                      abnormal CD8-positive, alpha-beta T cell number 6
                        increased CD8-positive, alpha-beta T cell number 1
                          increased CD8-positive, CD25-positive alpha-beta T cell number 0
                          increased CD8-positive, alpha-beta memory T cell number + 0
                          increased KLRG1+ CD8 alpha beta T cell number 0
                          increased Tc17 cell number 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.