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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased Leydig cell tumor incidence
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Accession:MP:0009592 term browser browse the term
Definition:greater than the expected number of rare testicular tumors of the male gonadal interstitium, occurring in a specific population in a given time period; Leydig cell tumors are frequently hormonally active, leading to feminizing or virilizing syndromes; Leydig cell tumors comprise 1-3% of all testicular neoplasms, can be pure or mixed with other sex cord-stromal or germ cell tumors, and are usually benign, although malignant variants also occur
Synonyms:exact_synonym: increased Leydig cell tumour incidence;   interstitial cell tumor of testis;   interstitial cell tumour of testis
 related_synonym: Leydig cell tumor;   Leydig cell tumour


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Path 1
Term Annotations click to browse term
  mammalian phenotype 4999
    endocrine/exocrine gland phenotype 324
      abnormal gland morphology 272
        increased gland tumor incidence 83
          increased testis tumor incidence 1
            increased Leydig cell tumor incidence 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 4999
    neoplasm 230
      altered tumor susceptibility 223
        abnormal tumor incidence 212
          abnormal organ/body region tumor incidence 182
            increased organ/body region tumor incidence 132
              increased reproductive system tumor incidence 10
                increased gonad tumor incidence 1
                  increased testis tumor incidence 1
                    increased Leydig cell tumor incidence 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.