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ONTOLOGY REPORT - ANNOTATIONS


Term:abnormal blood homeostasis
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Accession:MP:0009642 term browser browse the term
Definition:anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood
Synonyms:exact_synonym: abnormal blood chemistry;   blood chemistry abnormalities
 alt_id: MP:0000179;   MP:0001546


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abnormal circulating aspartate transaminase level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:13462048
abnormal circulating free fatty acids level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:68930
RGD:1600636
abnormal circulating protein level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11566051
abnormal hemostasis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:4889487
decreased blood uric acid level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fh fumarate hydratase JBrowse link 13 93,651,486 93,677,371 RGD:13792708
G Fhem1 fumarate hydratase; TALEN induced mutant 1 RGD:13792708
decreased circulating alanine transaminase level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462048
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:13462048
decreased circulating alkaline phosphatase level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:14696717
G Htr7em1Msu 5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu RGD:14696717
decreased circulating aspartate transaminase level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462048
decreased circulating bicarbonate level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 JBrowse link 8 33,490,280 33,519,127 RGD:13782272
G Kcnj1em1Kasu potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu RGD:13782272
decreased circulating bilirubin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462048
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:13462048
decreased circulating cholesterol level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:14696717
G Htr7em1Msu 5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu RGD:14696717
decreased circulating copper level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7bhts ATPase copper transporting beta; hepatitis RGD:2292672
decreased circulating creatinine level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:14398462
G Cd40em1Uthal CD40 molecule; ZFN induced mutant 1, Uthal RGD:14398462
decreased circulating estradiol level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:704424
decreased circulating glucose level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:2301945
G Glp1r glucagon-like peptide 1 receptor JBrowse link 20 9,586,075 9,626,228 RGD:625448
decreased circulating HDL cholesterol level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7bhts ATPase copper transporting beta; hepatitis RGD:2292672
decreased circulating leptin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 1 225,035,956 225,046,137 RGD:11085488
G Bscl2m1Kyo BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo RGD:11085488
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:12910109
decreased circulating luteinizing hormone level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kiss1 KiSS-1 metastasis-suppressor JBrowse link 13 50,529,506 50,537,603 RGD:10059342
decreased circulating potassium level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462048
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:13462048
decreased circulating progesterone level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:704424
decreased circulating prolactin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462048
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:13462048
decreased circulating serum albumin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:734959
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11566051
G F8em1Sage coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage RGD:11530071
decreased circulating total protein level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F8em1Sage coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage RGD:11530071
decreased circulating triglyceride level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:14696717
G Htr7em1Msu 5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu RGD:14696717
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462048
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:13462048
hyperglycemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:9835029
increased bleeding time term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lyst lysosomal trafficking regulator JBrowse link 17 90,323,055 90,522,091 RGD:1302441
G Rab38 RAB38, member RAS oncogene family JBrowse link 1 152,072,716 152,153,449 RGD:2324690
G Rab38ru Rab38, member of RAS oncogene family, ruby allele RGD:2324690
increased blood urea nitrogen level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11566051
G Fh fumarate hydratase JBrowse link 13 93,651,486 93,677,371 RGD:13792708
G Fhem1 fumarate hydratase; TALEN induced mutant 1 RGD:13792708
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 JBrowse link 8 33,490,280 33,519,127 RGD:13782272
G Kcnj1em1Kasu potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu RGD:13782272
increased circulating alanine transaminase level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7bhts ATPase copper transporting beta; hepatitis RGD:2292672
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:12910507
RGD:13432147
G Leprem3 leptin receptor; TALEN induced mutant 3 RGD:12910507
G Leprfa leptin receptor; fa mutant RGD:13432147
G P2ry2 purinergic receptor P2Y2 JBrowse link 1 166,031,228 166,045,423 RGD:2316657
increased circulating aldosterone level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:727991
increased circulating alkaline phosphatase level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamp2 lysosomal-associated membrane protein 2 JBrowse link X 124,722,628 124,766,079 RGD:13703118
G Lamp2em1 lysosomal-associated membrane protein 2; TALEN induced mutant1 RGD:13703118
G P2ry2 purinergic receptor P2Y2 JBrowse link 1 166,031,228 166,045,423 RGD:2316657
increased circulating aspartate transaminase level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamp2 lysosomal-associated membrane protein 2 JBrowse link X 124,722,628 124,766,079 RGD:13703118
G Lamp2em1 lysosomal-associated membrane protein 2; TALEN induced mutant1 RGD:13703118
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:12910507
G Leprem3 leptin receptor; TALEN induced mutant 3 RGD:12910507
increased circulating bilirubin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:14985241
G Abcc2TR- ATP binding cassette subfamily C member 2;transport deficient mutant , RGD:14985241
G Atp7bhts ATPase copper transporting beta; hepatitis RGD:2292672
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:13432067
G Ugt1a1j UDP glucuronosyltransferase family 1 member A1, jaundice mutant RGD:13432067
increased circulating cholesterol level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 1 225,035,956 225,046,137 RGD:11085488
G Bscl2m1Kyo BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo RGD:11085488
G Lamp2 lysosomal-associated membrane protein 2 JBrowse link X 124,722,628 124,766,079 RGD:13703118
G Lamp2em1 lysosomal-associated membrane protein 2; TALEN induced mutant1 RGD:13703118
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:8549777
G Lepm1Kyo leptin; ENU induced mutant1, Kyo RGD:8549777
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:12910507
RGD:12911216
RGD:13432147
G Leprem3 leptin receptor; TALEN induced mutant 3 RGD:12910507
G Leprem4Lizh leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh RGD:12911216
G Leprfa leptin receptor; fa mutant RGD:13432147
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:12880447
RGD:13462048
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:12880447
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:13825242
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr RGD:13825242
increased circulating corticosterone level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:727991
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:10449008
increased circulating creatine kinase level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:12880034
G Dmdem1Ang dystrophin; TALEN-induced mutant1, Ang RGD:12880034
increased circulating creatinine level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fh fumarate hydratase JBrowse link 13 93,651,486 93,677,371 RGD:13792708
G Fhem1 fumarate hydratase; TALEN induced mutant 1 RGD:13792708
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:12880447
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:12880447
increased circulating follicle stimulating hormone level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:8552987
G Esr1em1Soar estrogen receptor 1; ZFN induced mutant 1, Soar RGD:8552987
increased circulating free fatty acid level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:2301945
G Ldlrem1Sage low density lipoprotein receptor; ZFN induced mutant 1, Sage RGD:12910100
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:13825242
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr RGD:13825242
increased circulating glucose level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:2314405
G Lamp2 lysosomal-associated membrane protein 2 JBrowse link X 124,722,628 124,766,079 RGD:13703118
G Lamp2em1 lysosomal-associated membrane protein 2; TALEN induced mutant1 RGD:13703118
G Lepem1Sage leptin; zinc finger nuclease induced mutant1, Sage RGD:12904911
increased circulating HDL cholesterol level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lepem1Sage leptin; zinc finger nuclease induced mutant1, Sage RGD:12904911
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:12911216
G Leprem4Lizh leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh RGD:12911216
increased circulating insulin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 1 225,035,956 225,046,137 RGD:11085488
G Bscl2m1Kyo BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo RGD:11085488
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:2314405
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:13825242
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr RGD:13825242
increased circulating interleukin-6 level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:11533328
G Adora2bem2Mcwi adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin RGD:11533328
increased circulating LDL cholesterol level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lepem1Sage leptin; zinc finger nuclease induced mutant1, Sage RGD:12904911
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:12911216
G Leprem4Lizh leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh RGD:12911216
increased circulating leptin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fabp4 fatty acid binding protein 4 JBrowse link 2 93,792,666 93,797,267 RGD:737686
G Ldlrem1Sage low density lipoprotein receptor; ZFN induced mutant 1, Sage RGD:12910100
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:6478803
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr RGD:6478803
increased circulating luteinizing hormone level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:8552987
G Esr1em1Soar estrogen receptor 1; ZFN induced mutant 1, Soar RGD:8552987
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462048
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:13462048
increased circulating phosphate level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc6 ATP binding cassette subfamily C member 6 JBrowse link 1 101,954,786 102,013,252 RGD:13792593
G Abcc6em2Qlju ATP-binding cassette, subfamily C (CFTR/MRP), member 6; zinc finger nuclease induced mutant 2, Qiaoli Li RGD:13792593
increased circulating potassium level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 JBrowse link 8 33,490,280 33,519,127 RGD:13782272
G Kcnj1em1Kasu potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu RGD:13782272
increased circulating serum albumin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462048
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs RGD:13462048
increased circulating sodium level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 JBrowse link 8 33,490,280 33,519,127 RGD:13782272
G Kcnj1em1Kasu potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu RGD:13782272
increased circulating testosterone level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462048
increased circulating triglyceride level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 1 225,035,956 225,046,137 RGD:11085488
G Bscl2m1Kyo BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo RGD:11085488
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:2301945
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:8549777
G Lepm1Kyo leptin; ENU induced mutant1, Kyo RGD:8549777
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:12910507
RGD:12911216
G Leprem3 leptin receptor; TALEN induced mutant 3 RGD:12910507
G Leprem4Lizh leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh RGD:12911216
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:13825242
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr RGD:13825242
increased circulating tyrosine level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fah fumarylacetoacetate hydrolase JBrowse link 1 146,713,663 146,736,339 RGD:14398823
G Fahem15Dlli-/- fumarylacetoacetate hydrolase; CRISPR/Cas9 induced mutant 15, Dlli RGD:14398823
increased glycosylated hemoglobin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:13825242
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr RGD:13825242
increased partial thromboplastin time term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F8em1Sage coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage RGD:11530071

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  mammalian phenotype 4930
    homeostasis/metabolism phenotype 1064
      abnormal homeostasis 1003
        abnormal blood homeostasis 585
          abnormal blood gas level + 0
          abnormal blood osmolality + 1
          abnormal blood oxygen capacity + 0
          abnormal blood pH regulation + 0
          abnormal blood urea nitrogen level + 23
          abnormal blood uric acid level + 3
          abnormal circulating amino acid level + 37
          abnormal circulating ammonia level + 0
          abnormal circulating bicarbonate level + 4
          abnormal circulating bilirubin level + 12
          abnormal circulating fructosamine level + 1
          abnormal circulating glucose level + 171
          abnormal circulating hormone level + 208
          abnormal circulating hyaluronic acid level 0
          abnormal circulating ketone body level + 1
          abnormal circulating lactate level + 0
          abnormal circulating lipid level + 255
          abnormal circulating lipoprotein level + 42
          abnormal circulating mineral level + 13
          abnormal circulating protein level + 56
          abnormal hemostasis + 14
          cyanosis 0
          uremia + 32
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.