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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal lung lobe morphology
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Accession:MP:0010975 term browser browse the term
Definition:any structural anomaly of any of the anatomically and functionally distinct subunits (lobes) comprising the left or right lung, where each lobe receives air from its own secondary bronchus and is separated from it neighbors by one or more fissures (walls of connective tissue)
Comment:The human right lung is divided into three lobes as opposed to two lobes on the left, while the mouse right lung consists of four lobes as opposed to a single lobe on the left.


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fused right lung lobes term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Frem2 FRAS1 related extracellular matrix 2 IAGP RGD PMID:21756877 RGD:13464328 NCBI chr 2:142,747,501...142,885,604
Ensembl chr 2:142,747,501...142,885,604
JBrowse link
G Frem2fpl Fras1 related extracellular matrix protein 2;fpl mutant IAGP RGD PMID:21756877 RGD:13464328

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  mammalian phenotype 4967
    respiratory system phenotype 16
      abnormal respiratory system morphology 15
        abnormal lung morphology 12
          abnormal lung lobe morphology 3
            abnormal right lung accessory lobe morphology + 0
            abnormal right lung caudal lobe morphology 0
            abnormal right lung cranial lobe morphology 0
            abnormal right lung middle lobe morphology 0
            fused right lung lobes 3
            impaired lung lobe morphogenesis 0
            small lung lobe 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.