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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingolipid metabolic pathway
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Accession:PW:0000197 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of sphingolipids - important components of animal and plant membranes. They contain a long chain amino alcohol and a ceramide core. Ceramides are also the precursors of glycolipids, also referred to as glycosphingolipids, which have attached sugar(s).
Synonyms:related_synonym: KEGG:00600;   SMP:00034


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sphingolipid metabolic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acer1 alkaline ceramidase 1 JBrowse link 9 10,061,978 10,093,588 RGD:6907045
RGD:10402751
G Acer2 alkaline ceramidase 2 JBrowse link 5 105,230,540 105,279,732 RGD:6907045
G Acer3 alkaline ceramidase 3 JBrowse link 1 163,160,987 163,263,621 RGD:6907045
RGD:10402751
G Arsa arylsulfatase A JBrowse link 7 130,446,644 130,452,632 RGD:6907045
RGD:10402751
G Asah1 N-acylsphingosine amidohydrolase 1 JBrowse link 16 53,998,604 54,030,006 RGD:6907045
G Asah2 N-acylsphingosine amidohydrolase 2 JBrowse link 1 250,557,042 250,665,083 RGD:6907045
G B4galt6 beta-1,4-galactosyltransferase 6 JBrowse link 18 15,462,913 15,525,584 RGD:6907045
RGD:10402751
G Cerk ceramide kinase JBrowse link 7 127,015,162 127,058,056 RGD:6907045
RGD:10402751
G Degs1 delta(4)-desaturase, sphingolipid 1 JBrowse link 13 100,665,265 100,672,731 RGD:6907045
G Degs2 delta(4)-desaturase, sphingolipid 2 JBrowse link 6 132,591,968 132,608,600 RGD:6907045
RGD:10402751
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 10 108,095,131 108,099,483 RGD:6907045
RGD:10402751
G Gal3st1 galactose-3-O-sulfotransferase 1 JBrowse link 14 84,231,473 84,247,371 RGD:10402751
G Galc galactosylceramidase JBrowse link 6 122,177,195 122,239,411 RGD:6907045
RGD:10402751
G Gba glucosylceramidase beta JBrowse link 2 188,511,781 188,522,602 RGD:6907045
RGD:10402751
G Gla galactosidase, alpha JBrowse link X 105,405,915 105,417,331 RGD:6907045
RGD:10402751
G Glb1 galactosidase, beta 1 JBrowse link 8 122,439,328 122,511,939 RGD:6907045
RGD:10402751
G Kdsr 3-ketodihydrosphingosine reductase JBrowse link 13 26,779,386 26,812,271 RGD:6907045
RGD:10402751
G Neu1 neuraminidase 1 JBrowse link 20 4,610,995 4,615,258 RGD:6907045
G Neu2 neuraminidase 2 JBrowse link 9 94,702,095 94,724,903 RGD:6907045
G Neu3 neuraminidase 3 JBrowse link 1 164,803,574 164,814,777 RGD:6907045
RGD:10402751
G Neu4 neuraminidase 4 JBrowse link 9 101,284,902 101,290,558 RGD:6907045
G Plpp1 phospholipid phosphatase 1 JBrowse link 2 44,664,076 44,726,820 RGD:6907045
RGD:10402751
G Plpp2 phospholipid phosphatase 2 JBrowse link 7 13,062,168 13,070,281 RGD:6907045
G Plpp3 phospholipid phosphatase 3 JBrowse link 5 124,690,214 124,765,499 RGD:6907045
G RGD1564463 similar to Mdes protein JBrowse link 13 99,374,006 99,395,804 RGD:6907045
G Sgms1 sphingomyelin synthase 1 JBrowse link 1 250,692,448 250,951,685 RGD:6907045
RGD:10402751
G Sgms2 sphingomyelin synthase 2 JBrowse link 2 236,458,276 236,530,667 RGD:6907045
G Sgpl1 sphingosine-1-phosphate lyase 1 JBrowse link 20 30,699,936 30,769,178 RGD:6907045
RGD:10402751
G Sgpp1 sphingosine-1-phosphate phosphatase 1 JBrowse link 6 98,675,324 98,696,492 RGD:6907045
G Sgpp2 sphingosine-1-phosphate phosphatase 2 JBrowse link 9 84,203,094 84,321,269 RGD:6907045
RGD:10402751
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link 1 170,383,682 170,387,525 RGD:6907045
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link 20 46,212,070 46,215,183 RGD:6907045
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:6907045
G Smpd4 sphingomyelin phosphodiesterase 4 JBrowse link 11 87,522,971 87,546,687 RGD:6907045
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:6907045
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:6907045
RGD:10402751
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 JBrowse link 17 11,856,525 11,895,566 RGD:6907045
RGD:10402751
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 JBrowse link 6 111,334,408 111,417,960 RGD:6907045
RGD:10402751
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 JBrowse link 3 132,560,437 132,689,313 RGD:6907045
G Ugcg UDP-glucose ceramide glucosyltransferase JBrowse link 5 76,376,722 76,419,564 RGD:6907045
RGD:10402751
G Ugt8 UDP glycosyltransferase 8 JBrowse link 2 229,644,373 229,718,678 RGD:6907045
RGD:10402751
ganglioside metabolic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B3galt4 Beta-1,3-galactosyltransferase 4 JBrowse link 20 5,446,104 5,447,679 RGD:6907045
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 JBrowse link 7 70,439,273 70,459,556 RGD:6907045
G Glb1 galactosidase, beta 1 JBrowse link 8 122,439,328 122,511,939 RGD:6907045
G Hexa hexosaminidase subunit alpha JBrowse link 8 64,325,435 64,350,775 RGD:6907045
G Hexb hexosaminidase subunit beta JBrowse link 2 27,983,925 28,003,260 RGD:6907045
G Slc33a1 solute carrier family 33 member 1 JBrowse link 2 154,520,170 154,542,981 RGD:6907045
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 JBrowse link 7 107,895,045 107,963,158 RGD:6907045
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 JBrowse link 19 43,273,251 43,324,265 RGD:6907045
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 JBrowse link 4 99,937,499 99,999,905 RGD:6907045
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 JBrowse link 2 259,379,653 259,918,813 RGD:6907045
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 JBrowse link 3 11,607,103 11,619,595 RGD:6907045
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 JBrowse link 2 258,025,177 259,150,709 RGD:6907045
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 JBrowse link 3 11,620,050 11,641,460 RGD:6907045
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 JBrowse link 4 177,065,266 177,195,942 RGD:6907045
G St8sia5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 JBrowse link 18 73,564,010 73,630,256 RGD:6907045
globoside metabolic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A4galt alpha 1,4-galactosyltransferase (P blood group) JBrowse link 7 124,085,832 124,110,440 RGD:6907045
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) JBrowse link 2 166,226,736 166,255,978 RGD:6907045
G B3galt5 Beta-1,3-galactosyltransferase 5 JBrowse link 11 36,638,067 36,683,915 RGD:6907045
G Fut1 fucosyltransferase 1 JBrowse link 1 101,599,018 101,602,440 RGD:6907045
G Fut2 fucosyltransferase 2 JBrowse link 1 101,631,633 101,651,668 RGD:6907045
G Fut9 fucosyltransferase 9 JBrowse link 5 40,032,855 40,237,591 RGD:6907045
G Gla galactosidase, alpha JBrowse link X 105,405,915 105,417,331 RGD:6907045
G Hexa hexosaminidase subunit alpha JBrowse link 8 64,325,435 64,350,775 RGD:6907045
G Hexb hexosaminidase subunit beta JBrowse link 2 27,983,925 28,003,260 RGD:6907045
G Naga alpha-N-acetylgalactosaminidase JBrowse link 7 123,563,047 123,572,074 RGD:6907045
G Sec1 secretory blood group 1 JBrowse link 1 101,663,205 101,677,016 RGD:6907045
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 JBrowse link 7 107,895,045 107,963,158 RGD:6907045
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 JBrowse link 19 43,273,251 43,324,265 RGD:6907045
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 JBrowse link 4 177,065,266 177,195,942 RGD:6907045
lacto-series glycosphingolipid metabolic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase JBrowse link 3 4,374,679 4,394,374 RGD:6907045
G Abo2 histo-blood group ABO system transferase 2 JBrowse link 3 5,386,434 5,402,666 RGD:6907045
G B3galt1 Beta-1,3-galactosyltransferase 1 JBrowse link 3 53,699,409 54,269,612 RGD:6907045
G B3galt2 Beta-1,3-galactosyltransferase 2 JBrowse link 13 60,435,946 60,444,957 RGD:6907045
G B3galt5 Beta-1,3-galactosyltransferase 5 JBrowse link 11 36,638,067 36,683,915 RGD:6907045
G B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 JBrowse link 14 107,592,336 107,617,189 RGD:6907045
G B3gnt3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 JBrowse link 16 20,123,948 20,133,482 RGD:6907045
G B3gnt4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 JBrowse link 12 38,503,361 38,506,793 RGD:6907045
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 JBrowse link 11 84,919,055 84,931,160 RGD:6907045
G B4galt1 beta-1,4-galactosyltransferase 1 JBrowse link 5 57,121,768 57,168,610 RGD:6907045
G B4galt2 beta-1,4-galactosyltransferase 2 JBrowse link 5 136,707,510 136,717,345 RGD:6907045
G B4galt3 beta-1,4-galactosyltransferase 3 JBrowse link 13 89,643,847 89,649,880 RGD:6907045
G B4galt4 beta-1,4-galactosyltransferase 4 JBrowse link 11 64,558,006 64,584,054 RGD:6907045
G B4gat1 beta-1,4-glucuronyltransferase 1 JBrowse link 1 220,322,854 220,325,076 RGD:6907045
G Fut1 fucosyltransferase 1 JBrowse link 1 101,599,018 101,602,440 RGD:6907045
G Fut2 fucosyltransferase 2 JBrowse link 1 101,631,633 101,651,668 RGD:6907045
G Fut4 fucosyltransferase 4 JBrowse link 8 13,258,768 13,262,729 RGD:6907045
G Fut7 fucosyltransferase 7 JBrowse link 3 2,637,281 2,646,497 RGD:6907045
G Fut9 fucosyltransferase 9 JBrowse link 5 40,032,855 40,237,591 RGD:6907045
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) JBrowse link 17 21,634,546 21,677,477 RGD:6907045
G Ggta1 glycoprotein, alpha-galactosyltransferase 1 JBrowse link 3 14,614,099 14,701,185 RGD:6907045
G Sec1 secretory blood group 1 JBrowse link 1 101,663,205 101,677,016 RGD:6907045
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 JBrowse link 5 136,765,309 136,965,642 RGD:6907045
G St3gal4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 JBrowse link 8 36,264,741 36,314,811 RGD:6907045
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 JBrowse link 11 44,176,518 44,237,119 RGD:6907045
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 JBrowse link 4 177,065,266 177,195,942 RGD:6907045

Term paths to the root
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Term Annotations click to browse term
  pathway 6016
    classic metabolic pathway 1851
      lipid metabolic pathway 488
        sphingolipid metabolic pathway 83
          altered sphingolipid metabolic pathway + 0
          glycosphingolipid metabolic pathway + 44
          sphingolipid biosynthetic pathway 0
          sphingolipid degradation pathway 0
          sphingomyelin metabolic pathway + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.