Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:Wnt signaling, canonical pathway
go back to main search page
Accession:PW:0000201 term browser browse the term
Definition:Wnt signaling pathway is involved in many developmental processes. In the conventional or canonical Wnt pathway, beta-catenin is a central component required for the transcriptional control of Wnt signaling target genes.
Synonyms:related_synonym: PID:200077;   beta-catenin dependent Wnt signaling pathway

View Interactive Diagram


show annotations for term's descendants       view all columns           Sort by:
 
Wnt signaling, canonical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APC APC regulator of WNT signaling pathway JBrowse link 5 112,707,498 112,846,239 RGD:2293188
RGD:6484113
G AXIN1 axin 1 JBrowse link 16 287,440 355,226 RGD:2293188
RGD:6484113
G AXIN2 axin 2 JBrowse link 17 65,528,563 65,561,648 RGD:2293188
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 10 101,353,808 101,557,321 RGD:2293188
G CAV1 caveolin 1 JBrowse link 7 116,525,009 116,561,185 RGD:6484113
G CREBBP CREB binding protein JBrowse link 16 3,725,054 3,880,727 RGD:2302032
G CSNK1A1 casein kinase 1 alpha 1 JBrowse link 5 149,492,982 149,551,439 RGD:2293188
G CSNK1G1 casein kinase 1 gamma 1 JBrowse link 15 64,165,525 64,356,173 RGD:2293188
RGD:6484113
G CTNNB1 catenin beta 1 JBrowse link 3 41,199,422 41,240,445 RGD:1581696
RGD:7242068
RGD:6484113
RGD:2293188
G CUL3 cullin 3 JBrowse link 2 224,470,150 224,585,397 RGD:6484113
G DKK1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 10 52,314,281 52,317,657 RGD:2293188
RGD:2301921
G DKK2 dickkopf WNT signaling pathway inhibitor 2 JBrowse link 4 106,921,802 107,036,313 RGD:2301921
G DKK4 dickkopf WNT signaling pathway inhibitor 4 JBrowse link 8 42,373,194 42,391,322 RGD:2301921
G DVL1 dishevelled segment polarity protein 1 JBrowse link 1 1,335,278 1,349,418 RGD:1581696
RGD:6484113
G DVL2 dishevelled segment polarity protein 2 JBrowse link 17 7,225,341 7,234,544 RGD:6484113
G DVL3 dishevelled segment polarity protein 3 JBrowse link 3 184,155,311 184,173,614 RGD:6484113
G FRZB frizzled related protein JBrowse link 2 182,833,275 182,866,637 RGD:7365107
G FZD1 frizzled class receptor 1 JBrowse link 7 91,264,433 91,271,326 RGD:2293491
G FZD10 frizzled class receptor 10 JBrowse link 12 130,162,459 130,165,740 RGD:2293491
G FZD5 frizzled class receptor 5 JBrowse link 2 207,753,889 207,769,906 RGD:6484113
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 19 42,230,186 42,243,330 RGD:6484113
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 119,821,321 120,095,823 RGD:1581696
RGD:7242068
RGD:6484113
RGD:2293188
G KLHL12 kelch like family member 12 JBrowse link 1 202,891,116 202,928,628 RGD:6484113
G KREMEN1 kringle containing transmembrane protein 1 JBrowse link 22 29,073,035 29,168,333 RGD:2301921
G KREMEN2 kringle containing transmembrane protein 2 JBrowse link 16 2,964,275 2,968,380 RGD:2301921
G LEF1 lymphoid enhancer binding factor 1 JBrowse link 4 108,047,545 108,168,956 RGD:2293188
RGD:2301908
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 JBrowse link 11 27,365,961 27,472,790 RGD:7365107
G LGR5 leucine rich repeat containing G protein-coupled receptor 5 JBrowse link 12 71,439,798 71,586,310 RGD:7365107
G LRP5 LDL receptor related protein 5 JBrowse link 11 68,298,866 68,449,275 RGD:2293188
RGD:2293491
G LRP6 LDL receptor related protein 6 JBrowse link 12 12,116,025 12,267,044 RGD:2293188
RGD:6484113
G NDP norrin cystine knot growth factor NDP JBrowse link X 43,948,776 43,973,390 RGD:7365107
G NKD2 NKD inhibitor of WNT signaling pathway 2 JBrowse link 5 1,008,802 1,038,943 RGD:6484113
G PI4K2A phosphatidylinositol 4-kinase type 2 alpha JBrowse link 10 97,640,686 97,676,434 RGD:6484113
G PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta JBrowse link 9 68,705,240 69,009,176 RGD:6484113
G PORCN porcupine O-acyltransferase JBrowse link X 48,508,992 48,520,814 RGD:7365109
G PPP2R5A protein phosphatase 2 regulatory subunit B'alpha JBrowse link 1 212,285,410 212,361,853 RGD:6484113
G RANBP3 RAN binding protein 3 JBrowse link 19 5,916,139 5,978,140 RGD:6484113
G RNF43 ring finger protein 43 JBrowse link 17 58,352,500 58,418,894 RGD:7365105
G RSPO1 R-spondin 1 JBrowse link 1 37,611,350 37,634,906 RGD:7365105
G RSPO2 R-spondin 2 JBrowse link 8 107,899,316 108,083,680 RGD:7365105
G RSPO3 R-spondin 3 JBrowse link 6 127,118,671 127,199,481 RGD:7365105
G RSPO4 R-spondin 4 JBrowse link 20 958,452 1,002,311 RGD:7365105
G SFRP1 secreted frizzled related protein 1 JBrowse link 8 41,261,962 41,309,473 RGD:7365107
G SFRP2 secreted frizzled related protein 2 JBrowse link 4 153,780,591 153,789,083 RGD:7365107
G SFRP4 secreted frizzled related protein 4 JBrowse link 7 37,905,932 37,916,817 RGD:7365107
G SFRP5 secreted frizzled related protein 5 JBrowse link 10 97,766,751 97,771,999 RGD:7365107
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 19 10,960,997 11,062,277 RGD:2302032
G SOST sclerostin JBrowse link 17 43,753,738 43,758,791 RGD:7365107
G SOSTDC1 sclerostin domain containing 1 JBrowse link 7 16,461,481 16,465,738 RGD:7365107
G TCF7 transcription factor 7 JBrowse link 5 134,114,681 134,148,229 RGD:2301908
G TCF7L1 transcription factor 7 like 1 JBrowse link 2 85,133,392 85,310,387 RGD:2301908
G TCF7L2 transcription factor 7 like 2 JBrowse link 10 112,950,247 113,167,678 RGD:2301908
G TSC2 TSC complex subunit 2 JBrowse link 16 2,047,804 2,089,491 RGD:1304267
G WIF1 WNT inhibitory factor 1 JBrowse link 12 65,050,626 65,121,305 RGD:2293188
G WLS Wnt ligand secretion mediator JBrowse link 1 68,098,459 68,233,018 RGD:7365109
G WNT1 Wnt family member 1 JBrowse link 12 48,978,322 48,982,620 RGD:13209023
RGD:2313743
G WNT10A Wnt family member 10A JBrowse link 2 218,874,116 218,893,931 RGD:2300202
RGD:2313743
G WNT10B Wnt family member 10B JBrowse link 12 48,965,340 48,979,587 RGD:2300029
RGD:2313743
G WNT11 Wnt family member 11 JBrowse link 11 76,186,325 76,210,842 RGD:2313743
G WNT16 Wnt family member 16 JBrowse link 7 121,325,367 121,341,104 RGD:2313743
G WNT2 Wnt family member 2 JBrowse link 7 117,275,451 117,323,058 RGD:2313743
G WNT2B Wnt family member 2B JBrowse link 1 112,466,541 112,530,165 RGD:2313743
G WNT3 Wnt family member 3 JBrowse link 17 46,762,506 46,818,692 RGD:2313743
G WNT3A Wnt family member 3A JBrowse link 1 228,006,998 228,067,113 RGD:2300202
RGD:6484113
RGD:2313743
G WNT4 Wnt family member 4 JBrowse link 1 22,117,308 22,143,981 RGD:2313743
G WNT5A Wnt family member 5A JBrowse link 3 55,465,715 55,505,261 RGD:2313743
G WNT5B Wnt family member 5B JBrowse link 12 1,529,856 1,647,213 RGD:2313743
G WNT6 Wnt family member 6 JBrowse link 2 218,859,805 218,874,233 RGD:2313743
G WNT7A Wnt family member 7A JBrowse link 3 13,816,258 13,880,071 RGD:1601222
RGD:2313743
G WNT7B Wnt family member 7B JBrowse link 22 45,920,362 45,977,162 RGD:1601222
RGD:2313743
RGD:2293491
G WNT8A Wnt family member 8A JBrowse link 5 138,077,367 138,092,900 RGD:2313743
G WNT8B Wnt family member 8B JBrowse link 10 100,463,009 100,483,744 RGD:2313743
G WNT9A Wnt family member 9A JBrowse link 1 227,918,656 227,947,932 RGD:2300156
RGD:2313743
G WNT9B Wnt family member 9B JBrowse link 17 46,833,201 46,886,738 RGD:2313743
G ZNRF3 zinc and ring finger 3 JBrowse link 22 28,800,657 29,057,488 RGD:7365105
altered Wnt signaling, canonical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APC APC regulator of WNT signaling pathway JBrowse link 5 112,707,498 112,846,239 RGD:2293188
G AXIN1 axin 1 JBrowse link 16 287,440 355,226 RGD:2293188
G AXIN2 axin 2 JBrowse link 17 65,528,563 65,561,648 RGD:2293188
G CTNNB1 catenin beta 1 JBrowse link 3 41,199,422 41,240,445 RGD:2293188
RGD:4143515
G LRP5 LDL receptor related protein 5 JBrowse link 11 68,298,866 68,449,275 RGD:2293188
G TCF7L2 transcription factor 7 like 2 JBrowse link 10 112,950,247 113,167,678 RGD:5490966
G WNT9A Wnt family member 9A JBrowse link 1 227,918,656 227,947,932 RGD:5490966

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5944
    signaling pathway 2491
      signaling pathway pertinent to development 531
        Wnt signaling pathway 190
          Wnt signaling, canonical pathway 75
            altered Wnt signaling, canonical pathway 7
Path 2
Term Annotations click to browse term
  pathway 5944
    signaling pathway 2491
      glycoconjugated protein signaling pathway 412
        glycoprotein signaling pathway 296
          Wnt signaling pathway 190
            Wnt signaling, canonical pathway 75
              altered Wnt signaling, canonical pathway 7
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.