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ONTOLOGY REPORT - ANNOTATIONS


Term:insulin-like growth factor signaling pathway
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Accession:PW:0000238 term browser browse the term
Definition:Insulin-like growth factor signaling plays important roles in cell growth and proliferation. Produced primarily by the liver in response to stimulation by growth hormone (GH) , the proteins activate cognate receptors to prompt intracellular signaling pathways and cell growth in a variety of tissues. Deregulation of the pathway has been associated with various conditions, including cancer.
Synonyms:related_synonym: PID:200100


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insulin-like growth factor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G M Akt1 AKT serine/threonine kinase 1 RGD:9068941
G V AKT1 AKT serine/threonine kinase 1 JBrowse link 24 82,704,087 82,730,711 RGD:9068941
G P AKT1 AKT serine/threonine kinase 1 RGD:9068941
G S Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004936621 620,163 639,115 RGD:9068941
G D AKT1 AKT serine/threonine kinase 1 JBrowse link 8 72,317,399 72,335,686 RGD:9068941
G B AKT1 AKT serine/threonine kinase 1 JBrowse link 14 85,417,229 85,444,722 RGD:9068941
G C Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004955538 3,208,711 3,224,386 RGD:9068941
G R Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6484113
G M Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6484113
G H AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6484113
G M Bad BCL2 associated agonist of cell death RGD:9068941
G V BAD BCL2 associated agonist of cell death JBrowse link 1 9,949,717 9,964,433 RGD:9068941
G P BAD BCL2 associated agonist of cell death JBrowse link 2 7,831,192 7,842,864 RGD:9068941
G S Bad BCL2 associated agonist of cell death JBrowse link NW_004936599 4,924,349 4,933,683 RGD:9068941
G D BAD BCL2 associated agonist of cell death JBrowse link 18 52,781,335 52,791,789 RGD:9068941
G B BAD BCL2 associated agonist of cell death JBrowse link 11 59,626,981 59,641,824 RGD:9068941
G C Bad BCL2 associated agonist of cell death JBrowse link NW_004955422 20,795,585 20,809,039 RGD:9068941
G R Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:6484113
G M Bad BCL2-associated agonist of cell death JBrowse link 19 6,941,861 6,951,905 RGD:6484113
G H BAD BCL2 associated agonist of cell death JBrowse link 11 64,269,828 64,284,704 RGD:6484113
G M Bcar1 BCAR1 scaffold protein, Cas family member RGD:9068941
G V BCAR1 BCAR1 scaffold protein, Cas family member JBrowse link 5 60,709,409 60,749,071 RGD:9068941
G P BCAR1 BCAR1 scaffold protein, Cas family member JBrowse link 6 12,369,332 12,404,822 RGD:9068941
G S Bcar1 BCAR1 scaffold protein, Cas family member JBrowse link NW_004936475 23,994,130 24,032,829 RGD:9068941
G D BCAR1 BCAR1 scaffold protein, Cas family member JBrowse link 5 75,463,906 75,499,557 RGD:9068941
G B BCAR1 BCAR1 scaffold protein, Cas family member JBrowse link 16 55,798,578 55,838,448 RGD:9068941
G C Bcar1 BCAR1 scaffold protein, Cas family member JBrowse link NW_004955484 2,223,306 2,258,444 RGD:9068941
G R Bcar1 BCAR1 scaffold protein, Cas family member JBrowse link 19 43,932,543 43,967,452 RGD:6484113
G M Bcar1 breast cancer anti-estrogen resistance 1 JBrowse link 8 111,710,474 111,743,849 RGD:6484113
G H BCAR1 BCAR1 scaffold protein, Cas family member JBrowse link 16 75,228,181 75,268,007 RGD:6484113
G M Crk CRK proto-oncogene, adaptor protein RGD:9068941
G V CRK CRK proto-oncogene, adaptor protein JBrowse link 16 1,102,485 1,135,225 RGD:9068941
G P CRK CRK proto-oncogene, adaptor protein JBrowse link 12 47,656,805 47,685,641 RGD:9068941
G S Crk CRK proto-oncogene, adaptor protein JBrowse link NW_004936538 7,581,453 7,609,543 RGD:9068941
G D CRK CRK proto-oncogene, adaptor protein JBrowse link 9 45,594,657 45,627,499 RGD:9068941
G B CRK CRK proto-oncogene, adaptor protein JBrowse link 17 1,406,335 1,438,587 RGD:9068941
G C Crk CRK proto-oncogene, adaptor protein JBrowse link NW_004955481 1,705,595 1,748,363 RGD:9068941
G R Crk CRK proto-oncogene, adaptor protein JBrowse link 10 63,829,731 63,855,999 RGD:6484113
G M Crk v-crk avian sarcoma virus CT10 oncogene homolog JBrowse link 11 75,679,194 75,708,428 RGD:6484113
G H CRK CRK proto-oncogene, adaptor protein JBrowse link 17 1,420,693 1,456,232 RGD:6484113
G M Crkl CRK like proto-oncogene, adaptor protein RGD:9068941
G V CRKL CRK like proto-oncogene, adaptor protein JBrowse link 19 4,855,633 4,889,674 RGD:9068941
G P CRKL CRK like proto-oncogene, adaptor protein JBrowse link 14 50,528,950 50,558,664 RGD:9068941
G S Crkl CRK like proto-oncogene, adaptor protein JBrowse link NW_004936619 2,447,686 2,479,589 RGD:9068941
G D CRKL CRK like proto-oncogene, adaptor protein JBrowse link 26 30,542,276 30,582,479 RGD:9068941
G B CRKL CRK like proto-oncogene, adaptor protein JBrowse link 22 3,141,147 3,177,448 RGD:9068941
G C Crkl CRK like proto-oncogene, adaptor protein JBrowse link NW_004955442 19,358,202 19,388,552 RGD:9068941
G R Crkl CRK like proto-oncogene, adaptor protein JBrowse link 11 87,338,606 87,356,644 RGD:6484113
G M Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like JBrowse link 16 17,451,985 17,487,440 RGD:6484113
G H CRKL CRK like proto-oncogene, adaptor protein JBrowse link 22 20,917,407 20,953,747 RGD:6484113
G M Esr1 estrogen receptor 1 RGD:9068941
G V ESR1 estrogen receptor 1 JBrowse link 13 79,153,418 79,554,552 RGD:9068941
G P ESR1 estrogen receptor 1 JBrowse link 1 14,217,032 14,604,906 RGD:9068941
G S Esr1 estrogen receptor 1 JBrowse link NW_004936489 4,616,839 4,887,179 RGD:9068941
G D ESR1 estrogen receptor 1 JBrowse link 1 42,081,952 42,368,544 RGD:9068941
G B ESR1 estrogen receptor 1 JBrowse link 6 149,507,599 149,918,523 RGD:9068941
G C Esr1 estrogen receptor 1 JBrowse link NW_004955439 9,588,631 9,953,606 RGD:9068941
G R Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:7242068
G M Esr1 estrogen receptor 1 (alpha) JBrowse link 10 4,611,989 5,005,633 RGD:7242068
G H ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:7242068
G M Grb10 growth factor receptor bound protein 10 RGD:9068941
G V GRB10 growth factor receptor bound protein 10 JBrowse link 21 8,022,483 8,225,339 RGD:9068941
G P GRB10 growth factor receptor bound protein 10 JBrowse link 9 136,580,363 136,742,552 RGD:9068941
G S Grb10 growth factor receptor bound protein 10 JBrowse link NW_004936686 1,102,706 1,279,594 RGD:9068941
G D GRB10 growth factor receptor bound protein 10 JBrowse link 18 1,890,689 2,014,836 RGD:9068941
G B GRB10 growth factor receptor bound protein 10 JBrowse link 7 51,230,945 51,434,560 RGD:9068941
G C Grb10 growth factor receptor bound protein 10 JBrowse link NW_004955456 3,405,730 3,508,967 RGD:9068941
G R Grb10 growth factor receptor bound protein 10 JBrowse link 14 92,021,851 92,122,249 RGD:6484113
G M Grb10 growth factor receptor bound protein 10 JBrowse link 11 11,930,499 12,037,428 RGD:6484113
G H GRB10 growth factor receptor bound protein 10 JBrowse link 7 50,590,068 50,793,453 RGD:6484113
G M Grb2 growth factor receptor bound protein 2 RGD:9068941
G V GRB2 growth factor receptor bound protein 2 JBrowse link 16 46,264,818 46,346,426 RGD:9068941
G P GRB2 growth factor receptor bound protein 2 JBrowse link 12 5,940,723 6,009,095 RGD:9068941
G S Grb2 growth factor receptor bound protein 2 JBrowse link NW_004936594 592,760 661,369 RGD:9068941
G D GRB2 growth factor receptor bound protein 2 JBrowse link 9 5,108,128 5,182,091 RGD:9068941
G B GRB2 growth factor receptor bound protein 2 JBrowse link 17 69,265,307 69,352,835 RGD:9068941
G C Grb2 growth factor receptor bound protein 2 JBrowse link NW_004955553 2,186,590 2,258,964 RGD:9068941
G R Grb2 growth factor receptor bound protein 2 JBrowse link 10 104,193,953 104,263,071 RGD:1581313
RGD:6484113
G M Grb2 growth factor receptor bound protein 2 JBrowse link 11 115,644,045 115,708,597 RGD:1581313
RGD:6484113
G H GRB2 growth factor receptor bound protein 2 JBrowse link 17 75,318,076 75,405,709 RGD:1581313
RGD:6484113
G M Hras HRas proto-oncogene, GTPase RGD:9068941
G V HRAS HRas proto-oncogene, GTPase JBrowse link 1 343,613 345,782 RGD:9068941
G P HRAS HRas proto-oncogene, GTPase JBrowse link 2 299,662 302,539 RGD:9068941
G S Hras HRas proto-oncogene, GTPase JBrowse link NW_004936888 375,372 378,125 RGD:9068941
G D HRAS HRas proto-oncogene, GTPase JBrowse link 18 25,642,844 25,644,717 RGD:9068941
G B HRAS HRas proto-oncogene, GTPase JBrowse link 11 537,488 540,810 RGD:9068941
G C Hras HRas proto-oncogene, GTPase JBrowse link NW_004955476 11,508,446 11,510,333 RGD:9068941
G R Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:6484113
G M Hras Harvey rat sarcoma virus oncogene JBrowse link 7 141,189,934 141,194,019 RGD:6484113
G H HRAS HRas proto-oncogene, GTPase JBrowse link 11 532,242 535,576 RGD:6484113
G M Igf1 insulin like growth factor 1 RGD:9068941
G V IGF1 insulin like growth factor 1 JBrowse link 11 97,624,498 97,708,730 RGD:9068941
G P IGF1 insulin like growth factor 1 JBrowse link 5 81,762,027 81,909,253 RGD:9068941
G S Igf1 insulin like growth factor 1 JBrowse link NW_004936492 11,709,623 11,784,028 RGD:9068941
G D IGF1 insulin like growth factor 1 JBrowse link 15 41,203,320 41,275,964 RGD:9068941
G B IGF1 insulin like growth factor 1 JBrowse link 12 99,986,887 100,066,773 RGD:9068941
G C Igf1 insulin like growth factor 1 JBrowse link NW_004955405 37,505,830 37,582,152 RGD:9068941
G R Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1580473
RGD:12904768
RGD:6484113
RGD:1626333
G M Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:1580473
RGD:12904768
RGD:6484113
RGD:1626333
G H IGF1 insulin like growth factor 1 JBrowse link 12 102,395,860 102,481,839 RGD:1580473
RGD:12904768
RGD:6484113
RGD:1626333
G M Igf1r insulin like growth factor 1 receptor RGD:9068941
G V IGF1R insulin like growth factor 1 receptor JBrowse link 29 17,212,206 17,534,036 RGD:9068941
G P IGF1R insulin like growth factor 1 receptor JBrowse link 1 137,383,623 137,691,038 RGD:9068941
G S Igf1r insulin like growth factor 1 receptor JBrowse link NW_004936483 4,563,995 4,860,231 RGD:9068941
G D IGF1R insulin like growth factor 1 receptor JBrowse link 3 41,795,337 42,096,255 RGD:9068941
G B IGF1R insulin like growth factor 1 receptor JBrowse link 15 77,332,926 77,648,474 RGD:9068941
G C Igf1r insulin like growth factor 1 receptor JBrowse link NW_004955416 26,101,090 26,382,660 RGD:9068941
G R Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:1581313
RGD:7242068
RGD:6484113
RGD:1626333
G M Igf1r insulin-like growth factor I receptor JBrowse link 7 67,952,257 68,233,668 RGD:1581313
RGD:7242068
RGD:6484113
RGD:1626333
G H IGF1R insulin like growth factor 1 receptor JBrowse link 15 98,648,539 98,964,530 RGD:1581313
RGD:7242068
RGD:6484113
RGD:1626333
G R Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:1626333
G M Igf2 insulin-like growth factor 2 JBrowse link 7 142,650,768 142,666,816 RGD:1626333
G H IGF2 insulin like growth factor 2 JBrowse link 11 2,129,112 2,149,603 RGD:1626333
G R Igfals insulin-like growth factor binding protein, acid labile subunit JBrowse link 10 14,240,308 14,243,554 RGD:1626333
G M Igfals insulin-like growth factor binding protein, acid labile subunit JBrowse link 17 24,877,844 24,882,011 RGD:1626333
G H IGFALS insulin like growth factor binding protein acid labile subunit JBrowse link 16 1,790,413 1,794,908 RGD:1626333
G R Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 14 87,448,716 87,453,783 RGD:1626333
G M Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 11 7,197,787 7,202,546 RGD:1626333
G H IGFBP1 insulin like growth factor binding protein 1 JBrowse link 7 45,888,488 45,893,660 RGD:1626333
G R Igfbp2 insulin-like growth factor binding protein 2 JBrowse link 9 80,118,029 80,144,804 RGD:1626333
G M Igfbp2 insulin-like growth factor binding protein 2 JBrowse link 1 72,824,480 72,852,474 RGD:1626333
G H IGFBP2 insulin like growth factor binding protein 2 JBrowse link 2 216,632,828 216,664,436 RGD:1626333
G R Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:1626333
G M Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 11 7,206,086 7,215,498 RGD:1626333
G H IGFBP3 insulin like growth factor binding protein 3 JBrowse link 7 45,912,245 45,921,272 RGD:1626333
G R Igfbp4 insulin-like growth factor binding protein 4 JBrowse link 10 86,950,555 86,962,563 RGD:1626333
G M Igfbp4 insulin-like growth factor binding protein 4 JBrowse link 11 99,040,005 99,052,655 RGD:1626333
G H IGFBP4 insulin like growth factor binding protein 4 JBrowse link 17 40,443,450 40,457,725 RGD:1626333
G R Igfbp5 insulin-like growth factor binding protein 5 JBrowse link 9 80,154,230 80,166,813 RGD:1626333
G M Igfbp5 insulin-like growth factor binding protein 5 JBrowse link 1 72,858,065 72,874,865 RGD:1626333
G H IGFBP5 insulin like growth factor binding protein 5 JBrowse link 2 216,672,105 216,695,549 RGD:1626333
G R Igfbp6 insulin-like growth factor binding protein 6 JBrowse link 7 143,749,385 143,754,018 RGD:1626333
G M Igfbp6 insulin-like growth factor binding protein 6 JBrowse link 15 102,144,186 102,149,512 RGD:1626333
G H IGFBP6 insulin like growth factor binding protein 6 JBrowse link 12 53,097,667 53,102,340 RGD:1626333
G M Irs1 insulin receptor substrate 1 RGD:9068941
G V IRS1 insulin receptor substrate 1 JBrowse link 10 112,748,283 112,812,368 RGD:9068941
G P IRS1 insulin receptor substrate 1 JBrowse link 15 128,245,846 128,307,321 RGD:9068941
G S Irs1 insulin receptor substrate 1 JBrowse link NW_004936525 9,064,442 9,125,972 RGD:9068941
G D IRS1 insulin receptor substrate 1 JBrowse link 25 39,624,554 39,687,991 RGD:9068941
G B IRS1 insulin receptor substrate 1 JBrowse link 2B 113,973,191 114,041,127 RGD:9068941
G C Irs1 insulin receptor substrate 1 JBrowse link NW_004955453 7,685,715 7,742,262 RGD:9068941
G R Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:1581313
RGD:6484113
G M Irs1 insulin receptor substrate 1 JBrowse link 1 82,233,105 82,291,439 RGD:1581313
RGD:6484113
G H IRS1 insulin receptor substrate 1 JBrowse link 2 226,731,317 226,798,790 RGD:1581313
RGD:6484113
G M Irs2 insulin receptor substrate 2 RGD:9068941
G V IRS2 insulin receptor substrate 2 JBrowse link 3 88,045,439 88,076,468 RGD:9068941
G P IRS2 insulin receptor substrate 2 JBrowse link 11 76,626,158 76,654,639 RGD:9068941
G S Irs2 insulin receptor substrate 2 JBrowse link NW_004936472 2,772,187 2,796,398 RGD:9068941
G D IRS2 insulin receptor substrate 2 JBrowse link 22 58,197,016 58,229,026 RGD:9068941
G B IRS2 insulin receptor substrate 2 JBrowse link 13 90,886,095 90,917,724 RGD:9068941
G C Irs2 insulin receptor substrate 2 JBrowse link NW_004955404 2,531,484 2,555,383 RGD:9068941
G R Irs2 insulin receptor substrate 2 JBrowse link 16 83,824,515 83,848,569 RGD:6484113
G M Irs2 insulin receptor substrate 2 JBrowse link 8 10,984,681 11,008,929 RGD:6484113
G H IRS2 insulin receptor substrate 2 JBrowse link 13 109,752,695 109,786,583 RGD:6484113
G R Irs4 insulin receptor substrate 4 JBrowse link X 113,003,824 113,018,088 RGD:2301084
G M Nck2 NCK adaptor protein 2 RGD:9068941
G V NCK2 NCK adaptor protein 2 JBrowse link 14 9,412,677 9,515,565 RGD:9068941
G P NCK2 NCK adaptor protein 2 JBrowse link 3 49,063,813 49,222,274 RGD:9068941
G S Nck2 NCK adaptor protein 2 JBrowse link NW_004936764 141,159 185,482 RGD:9068941
G D NCK2 NCK adaptor protein 2 JBrowse link 10 37,584,351 37,734,388 RGD:9068941
G B NCK2 NCK adaptor protein 2 JBrowse link 2A 95,939,197 96,089,163 RGD:9068941
G C Nck2 NCK adaptor protein 2 JBrowse link NW_004955470 10,487,962 10,593,046 RGD:9068941
G R Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:6484113
G M Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 JBrowse link 1 43,445,483 43,570,518 RGD:6484113
G H NCK2 NCK adaptor protein 2 JBrowse link 2 105,744,649 105,894,274 RGD:6484113
G M Pdpk1 3-phosphoinositide dependent protein kinase 1 RGD:9068941
G V PDPK1 3-phosphoinositide dependent protein kinase 1 RGD:9068941
G P PDPK1 3-phosphoinositide dependent protein kinase 1 JBrowse link 3 39,429,928 39,512,623 RGD:9068941
G S Pdpk1 3-phosphoinositide dependent protein kinase 1 JBrowse link NW_004936694 1,444,819 1,487,628 RGD:9068941
G D PDPK1 3-phosphoinositide dependent protein kinase 1 JBrowse link 6 38,426,464 38,506,520 RGD:9068941
G B PDPK1 3-phosphoinositide dependent protein kinase 1 JBrowse link 16 1,394,447 1,463,735 RGD:9068941
G C Pdpk1 3-phosphoinositide dependent protein kinase 1 JBrowse link NW_004955442 14,685,089 14,772,870 RGD:9068941
G R Pdpk1 3-phosphoinositide dependent protein kinase-1 JBrowse link 10 13,446,373 13,525,248 RGD:6484113
G M Pdpk1 3-phosphoinositide dependent protein kinase 1 JBrowse link 17 24,073,680 24,155,619 RGD:6484113
G H PDPK1 3-phosphoinositide dependent protein kinase 1 JBrowse link 16 2,538,014 2,603,190 RGD:6484113
G M Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha RGD:9068941
G V PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 15 10,218,034 10,304,874 RGD:9068941
G P PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 13 117,193,935 117,282,151 RGD:9068941
G S Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004936566 3,924,013 3,951,052 RGD:9068941
G D PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 34 12,600,140 12,681,905 RGD:9068941
G B PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 176,182,765 176,272,024 RGD:9068941
G C Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004955420 8,355,415 8,427,024 RGD:9068941
G R Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:6484113
G M Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,065 32,466,112 RGD:6484113
G H PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 179,148,114 179,240,093 RGD:6484113
G M Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 RGD:9068941
G V PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 4 64,321,296 64,406,188 RGD:9068941
G P PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 16 46,434,757 46,523,626 RGD:9068941
G S Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link NW_004936480 1,188,408 1,273,210 RGD:9068941
G D PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 53,447,802 53,527,563 RGD:9068941
G B PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 5 45,701,219 45,786,652 RGD:9068941
G C Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link NW_004955446 1,020,707 1,098,327 RGD:9068941
G R Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:6484113
G M Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 13 101,680,761 101,768,217 RGD:6484113
G H PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 5 68,215,737 68,301,821 RGD:6484113
G M Prkcd protein kinase C delta RGD:9068941
G V PRKCD protein kinase C delta JBrowse link 22 14,561,401 14,592,877 RGD:9068941
G P PRKCD protein kinase C delta JBrowse link 13 35,290,835 35,323,245 RGD:9068941
G S Prkcd protein kinase C delta JBrowse link NW_004936473 3,892,625 3,923,467 RGD:9068941
G D PRKCD protein kinase C delta JBrowse link 20 36,723,491 36,751,982 RGD:9068941
G B PRKCD protein kinase C delta JBrowse link 3 53,104,137 53,135,588 RGD:9068941
G C Prkcd protein kinase C delta JBrowse link NW_004955430 3,125,066 3,151,857 RGD:9068941
G R Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:6484113
G M Prkcd protein kinase C, delta JBrowse link 14 30,595,353 30,626,414 RGD:6484113
G H PRKCD protein kinase C delta JBrowse link 3 53,161,209 53,192,717 RGD:6484113
G M Prkcz protein kinase C zeta RGD:9068941
G V PRKCZ protein kinase C zeta JBrowse link 20 129,367,309 129,502,681 RGD:9068941
G P PRKCZ protein kinase C zeta JBrowse link 6 64,073,343 64,159,187 RGD:9068941
G S Prkcz protein kinase C zeta JBrowse link NW_004936737 1,303,502 1,383,135 RGD:9068941
G D PRKCZ protein kinase C zeta JBrowse link 5 57,012,020 57,113,346 RGD:9068941
G B PRKCZ protein kinase C zeta JBrowse link 1 763,942 901,531 RGD:9068941
G C Prkcz protein kinase C zeta JBrowse link NW_004955486 8,947,579 9,021,702 RGD:9068941
G R Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:6484113
G M Prkcz protein kinase C, zeta JBrowse link 4 155,260,118 155,361,428 RGD:6484113
G H PRKCZ protein kinase C zeta JBrowse link 1 2,050,411 2,185,399 RGD:6484113
G M Prkd1 protein kinase D1 RGD:9068941
G V PRKD1 protein kinase D1 JBrowse link 24 6,446,723 6,799,282 RGD:9068941
G P PRKD1 protein kinase D1 JBrowse link 7 69,527,743 69,872,374 RGD:9068941
G S Prkd1 protein kinase D1 JBrowse link NW_004936494 4,469,092 4,601,183 RGD:9068941
G D PRKD1 protein kinase D1 JBrowse link 8 9,004,641 9,327,054 RGD:9068941
G B PRKD1 protein kinase D1 JBrowse link 14 10,353,284 10,707,841 RGD:9068941
G C Prkd1 protein kinase D1 JBrowse link NW_004955409 30,554,095 30,860,588 RGD:9068941
G R Prkd1 protein kinase D1 JBrowse link 6 71,035,017 71,349,531 RGD:6484113
G M Prkd1 protein kinase D1 JBrowse link 12 50,341,226 50,649,271 RGD:6484113
G H PRKD1 protein kinase D1 JBrowse link 14 29,576,479 29,927,847 RGD:6484113
G M Ptpn1 protein tyrosine phosphatase non-receptor type 1 RGD:9068941
G V PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 2 13,385,681 13,459,180 RGD:9068941
G P PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 17 52,017,100 52,086,747 RGD:9068941
G S Ptpn1 protein tyrosine phosphatase non-receptor type 1 JBrowse link NW_004936514 4,065,455 4,083,847 RGD:9068941
G D PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 24 36,936,469 37,010,929 RGD:9068941
G B PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 20 46,854,918 46,929,509 RGD:9068941
G C Ptpn1 protein tyrosine phosphatase non-receptor type 1 JBrowse link NW_004955445 7,754,313 7,819,229 RGD:9068941
G R Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:6484113
G M Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 2 167,930,750 167,979,385 RGD:6484113
G H PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 20 50,510,321 50,585,241 RGD:6484113
G M Ptpn11 protein tyrosine phosphatase non-receptor type 11 RGD:9068941
G V PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 11 107,658,495 107,754,457 RGD:9068941
G P PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 14 39,202,165 39,292,041 RGD:9068941
G S Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004936668 2,602,261 2,687,903 RGD:9068941
G D PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 26 9,989,218 10,072,245 RGD:9068941
G B PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 12 110,016,364 110,107,462 RGD:9068941
G C Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004955482 8,934,734 9,031,230 RGD:9068941
G R Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:6484113
G M Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 5 121,130,533 121,191,397 RGD:6484113
G H PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 12 112,418,915 112,509,918 RGD:6484113
G M Pxn paxillin RGD:9068941
G V PXN paxillin JBrowse link 11 115,560,859 115,619,093 RGD:9068941
G P PXN paxillin JBrowse link 14 40,227,894 40,278,785 RGD:9068941
G S Pxn paxillin JBrowse link NW_004936668 660,415 709,282 RGD:9068941
G D PXN paxillin JBrowse link 26 16,157,231 16,224,028 RGD:9068941
G B PXN paxillin JBrowse link 12 117,785,614 117,840,816 RGD:9068941
G C Pxn paxillin JBrowse link NW_004955455 11,387,140 11,401,178 RGD:9068941
G R Pxn paxillin JBrowse link 12 46,797,953 46,845,107 RGD:6484113
G M Pxn paxillin JBrowse link 5 115,491,970 115,555,987 RGD:6484113
G H PXN paxillin JBrowse link 12 120,210,439 120,265,771 RGD:6484113
G M Rack1 receptor for activated C kinase 1 RGD:9068941
G V RACK1 receptor for activated C kinase 1 JBrowse link 23 82,800,211 82,805,769 RGD:9068941
G P RACK1 receptor for activated C kinase 1 JBrowse link 2 57,280,192 57,284,846 RGD:9068941
G S Rack1 receptor for activated C kinase 1 JBrowse link NW_004936826 748,256 753,460 RGD:9068941
G D RACK1 receptor for activated C kinase 1 JBrowse link 11 426,734 431,087 RGD:9068941
G B RACK1 receptor for activated C kinase 1 JBrowse link 5 176,462,991 176,470,153 RGD:9068941
G C Rack1 receptor for activated C kinase 1 JBrowse link NW_004955530 78,488 83,297 RGD:9068941
G R Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:6484113
G M Rack1 receptor for activated C kinase 1 JBrowse link 11 48,800,360 48,806,241 RGD:6484113
G H RACK1 receptor for activated C kinase 1 JBrowse link 5 181,236,897 181,243,906 RGD:6484113
G M Raf1 Raf-1 proto-oncogene, serine/threonine kinase RGD:9068941
G V RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 22 48,560,270 48,643,537 RGD:9068941
G P RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 13 68,581,128 68,657,911 RGD:9068941
G S Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link NW_004936602 1,089,979 1,114,376 RGD:9068941
G D RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 20 5,892,839 5,972,672 RGD:9068941
G B RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 3 12,510,084 12,590,598 RGD:9068941
G C Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link NW_004955429 17,980,956 18,049,723 RGD:9068941
G R Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:6484113
G M Raf1 v-raf-leukemia viral oncogene 1 JBrowse link 6 115,618,569 115,676,635 RGD:6484113
G H RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 3 12,583,601 12,664,117 RGD:6484113
G M Rps6kb1 ribosomal protein S6 kinase B1 RGD:9068941
G V RPS6KB1 ribosomal protein S6 kinase B1 JBrowse link 16 33,498,098 33,556,553 RGD:9068941
G P RPS6KB1 ribosomal protein S6 kinase B1 JBrowse link 12 36,111,584 36,159,287 RGD:9068941
G S Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link NW_004936490 3,441,046 3,492,917 RGD:9068941
G D RPS6KB1 ribosomal protein S6 kinase B1 JBrowse link 9 34,387,084 34,590,603 RGD:9068941
G B RPS6KB1 ribosomal protein S6 kinase B1 JBrowse link 17 53,958,807 54,014,752 RGD:9068941
G C Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link NW_004955451 3,181,085 3,225,610 RGD:9068941
G R Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:6484113
G M Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 JBrowse link 11 86,498,869 86,544,885 RGD:9068941
G H RPS6KB1 ribosomal protein S6 kinase B1 JBrowse link 17 59,893,046 59,950,574 RGD:6484113
G M Shc1 SHC adaptor protein 1 RGD:9068941
G V SHC1 SHC adaptor protein 1 JBrowse link 20 8,854,189 8,866,406 RGD:9068941
G P SHC1 SHC adaptor protein 1 JBrowse link 4 94,818,226 94,831,766 RGD:9068941
G S Shc1 SHC adaptor protein 1 JBrowse link NW_004936580 4,511,560 4,522,003 RGD:9068941
G D SHC1 SHC adaptor protein 1 JBrowse link 7 42,501,829 42,509,613 RGD:9068941
G B SHC1 SHC adaptor protein 1 JBrowse link 1 130,310,778 130,323,001 RGD:9068941
G C Shc1 SHC adaptor protein 1 JBrowse link NW_004955545 1,468,391 1,479,209 RGD:9068941
G R Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:6484113
G M Shc1 src homology 2 domain-containing transforming protein C1 JBrowse link 3 89,418,551 89,430,029 RGD:6484113
G H SHC1 SHC adaptor protein 1 JBrowse link 1 154,962,298 154,974,492 RGD:6484113
G M Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 RGD:9068941
G V SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 14 68,259,509 68,404,167 RGD:9068941
G P SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 3 101,209,568 101,366,057 RGD:9068941
G S Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link NW_004936508 12,162,553 12,281,812 RGD:9068941
G D SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 17 31,007,940 31,181,569 RGD:9068941
G B SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 2A 39,019,046 39,162,248 RGD:9068941
G C Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link NW_004955441 6,649,895 6,724,271 RGD:9068941
G R Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:6484113
G M Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 17 80,393,752 80,480,453 RGD:6484113
G H SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 2 38,981,549 39,124,868 RGD:6484113
G R Wdr6 WD repeat domain 6 JBrowse link 8 117,358,345 117,364,761 RGD:2301084
G M Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon RGD:9068941
G V YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon JBrowse link 16 1,031,840 1,086,950 RGD:9068941
G P YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon JBrowse link 12 47,601,133 47,645,327 RGD:9068941
G S Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon JBrowse link NW_004936538 7,518,283 7,558,458 RGD:9068941
G D YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon JBrowse link 9 45,506,830 45,562,081 RGD:9068941
G B YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon JBrowse link 17 1,332,004 1,387,120 RGD:9068941
G C Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon JBrowse link NW_004955481 1,752,778 1,805,700 RGD:9068941
G R Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon JBrowse link 10 63,884,338 63,921,709 RGD:6484113
G M Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide JBrowse link 11 75,732,887 75,765,841 RGD:6484113
G H YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon JBrowse link 17 1,344,275 1,400,262 RGD:6484113
G M Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta RGD:9068941
G V YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta JBrowse link 8 95,786,197 95,821,270 RGD:9068941
G P YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta JBrowse link 4 35,975,513 36,009,909 RGD:9068941
G S Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta JBrowse link NW_004936470 42,444,671 42,470,548 RGD:9068941
G D YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta JBrowse link 13 2,729,404 2,764,422 RGD:9068941
G B YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta JBrowse link 8 97,560,251 97,595,117 RGD:9068941
G C Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta JBrowse link NW_004955417 16,047,263 16,070,506 RGD:9068941
G R Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta JBrowse link 7 75,573,553 75,598,295 RGD:6484113
G M Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide JBrowse link 15 36,770,261 36,802,984 RGD:6484113
G H YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta JBrowse link 8 100,916,523 100,954,068 RGD:6484113
altered insulin-like growth factor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G M Igf1 insulin like growth factor 1 RGD:9068941
G V IGF1 insulin like growth factor 1 JBrowse link 11 97,624,498 97,708,730 RGD:9068941
G P IGF1 insulin like growth factor 1 JBrowse link 5 81,762,027 81,909,253 RGD:9068941
G S Igf1 insulin like growth factor 1 JBrowse link NW_004936492 11,709,623 11,784,028 RGD:9068941
G D IGF1 insulin like growth factor 1 JBrowse link 15 41,203,320 41,275,964 RGD:9068941
G B IGF1 insulin like growth factor 1 JBrowse link 12 99,986,887 100,066,773 RGD:9068941
G C Igf1 insulin like growth factor 1 JBrowse link NW_004955405 37,505,830 37,582,152 RGD:9068941
G R Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1580474
G M Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:1580474
G H IGF1 insulin like growth factor 1 JBrowse link 12 102,395,860 102,481,839 RGD:1580474

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 29473
    signaling pathway 14221
      growth factor signaling pathway 3210
        insulin-like growth factor signaling pathway 266
          altered insulin-like growth factor signaling pathway 8
Path 2
Term Annotations click to browse term
  pathway 29473
    signaling pathway 14221
      hormone signaling pathway 2958
        peptide and protein hormone signaling pathway 2318
          insulin-like growth factor signaling pathway 266
            altered insulin-like growth factor signaling pathway 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.