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ONTOLOGY REPORT - ANNOTATIONS


Term:endometrial cancer pathway
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Accession:PW:0000611 term browser browse the term
Definition:Endometrial cancer affects the lining of the uterus, or endometrium. Hormonal and genetic alterations play a role in the development of this carcinoma type. Mutations in genes acting in several pathways have been associated with the condition and its types.
Synonyms:related_synonym: KEGG:05213;   endometrial neoplasm pathway

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endometrial cancer pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 105,211,645 105,236,756 RGD:9068941
G AKT2 AKT serine/threonine kinase 2 JBrowse link 19 45,791,043 45,846,359 RGD:9068941
G AKT3 AKT serine/threonine kinase 3 JBrowse link 1 224,480,762 224,824,950 RGD:9068941
G APC APC regulator of WNT signaling pathway JBrowse link 5 113,873,993 114,009,709 RGD:9068941
G APC2 APC regulator of WNT signaling pathway 2 JBrowse link 19 1,421,433 1,445,686 RGD:9068941
G ARAF A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 47,893,153 47,904,643 RGD:9068941
G AXIN1 axin 1 JBrowse link 16 278,239 337,891 RGD:9068941
G AXIN2 axin 2 JBrowse link 17 64,688,416 64,720,086 RGD:9068941
G BAD BCL2 associated agonist of cell death JBrowse link 11 62,971,808 62,986,304 RGD:9068941
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 7 145,124,291 145,327,115 RGD:9068941
G CASP9 caspase 9 JBrowse link 1 15,624,666 15,656,266 RGD:9068941
G CCND1 cyclin D1 JBrowse link 11 68,029,134 68,041,553 RGD:9068941
G CDH1 cadherin 1 JBrowse link 16 68,502,399 68,597,748 RGD:9068941
G CTNNA1 catenin alpha 1 JBrowse link 5 140,261,883 140,438,854 RGD:9068941
G CTNNA2 catenin alpha 2 JBrowse link 2A 81,158,206 82,308,244 RGD:9068941
G CTNNA3 catenin alpha 3 JBrowse link 10 64,712,491 66,460,336 RGD:9068941
G CTNNB1 catenin beta 1 JBrowse link 3 41,372,368 41,414,030 RGD:9068941
G EGF epidermal growth factor JBrowse link 4 112,977,565 113,075,761 RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 7 56,048,212 56,117,642 RGD:9068941
G ELK1 ETS transcription factor ELK1 JBrowse link X 47,967,492 47,982,590 RGD:9068941
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 17 17,777,434 17,817,735 RGD:9068941
G FOXO3 forkhead box O3 JBrowse link 6 110,406,265 110,536,967 RGD:9068941
G GRB2 growth factor receptor bound protein 2 JBrowse link 17 74,817,471 74,904,022 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 123,856,047 124,126,747 RGD:9068941
G HRAS HRas proto-oncogene, GTPase JBrowse link 11 568,305 571,078 RGD:9068941
G ILK integrin linked kinase JBrowse link 11 6,418,717 6,425,788 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 12 63,679,293 63,724,335 RGD:9068941
G LEF1 lymphoid enhancer binding factor 1 JBrowse link 4 111,125,312 111,245,980 RGD:9068941
G LOC100977025 dual specificity mitogen-activated protein kinase kinase 2 JBrowse link 19 4,064,626 4,097,933 RGD:9068941
G LOC100986080 phosphatidylinositol 3-kinase regulatory subunit gamma JBrowse link 1 46,700,153 46,835,812 RGD:9068941
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 15 63,613,988 63,714,928 RGD:9068941
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 20,365,480 20,412,561 RGD:9068941
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,489,362 30,498,026 RGD:9068941
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G MSH6 mutS homolog 6 JBrowse link 2A 48,824,469 48,849,779 RGD:9068941
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 8 127,130,877 127,136,861 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 1 122,890,505 122,903,585 RGD:9068941
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 184,355,789 184,441,997 RGD:9068941
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta JBrowse link 3 143,288,563 143,431,314 RGD:9068941
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta JBrowse link 1 9,683,626 9,724,641 RGD:9068941
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 7 111,569,947 111,611,614 RGD:9068941
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 5 47,268,477 47,350,960 RGD:9068941
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 19 18,608,470 18,624,185 RGD:9068941
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 JBrowse link 17 47,421,204 47,507,282 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 10 88,093,539 88,197,902 RGD:9068941
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 3 12,853,415 12,932,871 RGD:9068941
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 2A 39,773,758 39,911,964 RGD:9068941
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 14 49,013,565 49,125,554 RGD:9068941
G TCF7 transcription factor 7 JBrowse link 5 135,671,630 135,704,417 RGD:9068941
G TCF7L1 transcription factor 7 like 1 JBrowse link 2A 86,739,422 86,914,829 RGD:9068941
G TCF7L2 transcription factor 7 like 2 JBrowse link 10 112,991,588 113,193,992 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941

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  pathway 5624
    disease pathway 1902
      cancer pathway 383
        urogenital cancer pathway 165
          endometrial cancer pathway 52
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.