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ONTOLOGY REPORT - ANNOTATIONS


Term:endometrial cancer pathway
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Accession:PW:0000611 term browser browse the term
Definition:Endometrial cancer affects the lining of the uterus, or endometrium. Hormonal and genetic alterations play a role in the development of this carcinoma type. Mutations in genes acting in several pathways have been associated with the condition and its types.
Synonyms:related_synonym: KEGG:05213;   endometrial neoplasm pathway

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endometrial cancer pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 8 72,317,399 72,335,686 RGD:9068941
G AKT2 AKT serine/threonine kinase 2 JBrowse link 1 113,359,038 113,407,119 RGD:9068941
G AKT3 AKT serine/threonine kinase 3 JBrowse link 7 34,633,064 34,931,112 RGD:9068941
G APC APC regulator of WNT signaling pathway JBrowse link 3 252,052 380,506 RGD:9068941
G APC2 APC regulator of WNT signaling pathway 2 JBrowse link 20 57,380,472 57,395,249 RGD:9068941
G ARAF A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 41,180,082 41,191,579 RGD:9068941
G AXIN1 axin 1 JBrowse link 6 40,155,797 40,218,330 RGD:9068941
G AXIN2 axin 2 JBrowse link 9 14,559,476 14,588,950 RGD:9068941
G BAD BCL2 associated agonist of cell death JBrowse link 18 52,781,335 52,791,789 RGD:9068941
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 16 8,222,909 8,318,179 RGD:9068941
G CASP9 caspase 9 JBrowse link 2 82,033,759 82,076,710 RGD:9068941
G CCND1 cyclin D1 JBrowse link 18 48,501,905 48,509,684 RGD:9068941
G CDH1 cadherin 1 JBrowse link 5 80,757,508 80,834,878 RGD:9068941
G CTNNA1 catenin alpha 1 JBrowse link 11 26,273,322 26,459,497 RGD:9068941
G CTNNA2 catenin alpha 2 JBrowse link 17 43,472,346 44,504,881 RGD:9068941
G CTNNA3 catenin alpha 3 JBrowse link 4 17,364,121 19,035,836 RGD:9068941
G CTNNB1 catenin beta 1 JBrowse link 23 10,559,722 10,572,933 RGD:9068941
G EGF epidermal growth factor JBrowse link 32 30,073,541 30,166,904 RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 18 5,983,669 6,044,092 RGD:9068941
G ELK1 ETS transcription factor ELK1 JBrowse link X 41,256,205 41,270,656 RGD:9068941
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 9 22,760,373 22,785,367 RGD:9068941
G FOXO3 forkhead box O3 JBrowse link 12 65,552,455 65,673,467 RGD:9068941
G GRB2 growth factor receptor bound protein 2 JBrowse link 9 5,108,128 5,182,091 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 33 23,458,369 23,659,878 RGD:9068941
G HRAS HRas proto-oncogene, GTPase JBrowse link 18 25,642,844 25,644,717 RGD:9068941
G ILK integrin linked kinase JBrowse link 21 29,911,326 29,917,972 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 27 22,261,753 22,296,704 RGD:9068941
G LEF1 lymphoid enhancer binding factor 1 JBrowse link 32 28,516,002 28,633,759 RGD:9068941
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 30 30,683,192 30,760,479 RGD:9068941
G MAP2K2 mitogen-activated protein kinase kinase 2 JBrowse link 20 55,465,460 55,487,629 RGD:9068941
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 26 31,013,607 31,132,998 RGD:9068941
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 6 18,109,184 18,115,728 RGD:9068941
G MLH1 mutL homolog 1 JBrowse link 23 6,889,108 6,938,117 RGD:9068941
G MSH6 mutS homolog 6 JBrowse link 10 49,825,330 49,838,036 RGD:9068941
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 13 25,200,772 25,205,309 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 17 52,411,733 52,418,788 RGD:9068941
G PDPK1 3-phosphoinositide dependent protein kinase 1 JBrowse link 6 38,426,464 38,506,520 RGD:9068941
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 34 12,600,140 12,681,905 RGD:9068941
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta JBrowse link 23 34,832,661 34,955,410 RGD:9068941
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta JBrowse link 5 62,884,596 62,936,882 RGD:9068941
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 18 13,576,966 13,611,748 RGD:9068941
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 53,447,802 53,527,563 RGD:9068941
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 20 44,826,037 44,838,449 RGD:9068941
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 JBrowse link 15 14,222,059 14,357,200 RGD:9068941
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 JBrowse link 5 33,538,354 33,604,984 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 26 37,853,148 37,913,176 RGD:9068941
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 20 5,892,839 5,972,672 RGD:9068941
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 17 31,007,940 31,181,569 RGD:9068941
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 8 26,636,849 26,698,837 RGD:9068941
G TCF7 transcription factor 7 JBrowse link 11 22,313,113 22,346,221 RGD:9068941
G TCF7L1 transcription factor 7 like 1 JBrowse link 17 39,699,958 39,859,167 RGD:9068941
G TCF7L2 transcription factor 7 like 2 JBrowse link 28 23,966,079 24,162,775 RGD:9068941
G TP53 tumor protein p53 JBrowse link 5 32,561,406 32,565,149 RGD:9068941

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  pathway 5642
    disease pathway 1936
      cancer pathway 384
        urogenital cancer pathway 165
          endometrial cancer pathway 53
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.