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ONTOLOGY REPORT - ANNOTATIONS


Term:endometrial cancer pathway
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Accession:PW:0000611 term browser browse the term
Definition:Endometrial cancer affects the lining of the uterus, or endometrium. Hormonal and genetic alterations play a role in the development of this carcinoma type. Mutations in genes acting in several pathways have been associated with the condition and its types.
Synonyms:related_synonym: KEGG:05213;   endometrial neoplasm pathway

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endometrial cancer pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6907045
G Akt2 thymoma viral proto-oncogene 2 JBrowse link 7 27,591,552 27,640,826 RGD:6907045
RGD:13432140
G Akt3 thymoma viral proto-oncogene 3 JBrowse link 1 177,020,076 177,261,781 RGD:6907045
G Apc APC, WNT signaling pathway regulator JBrowse link 18 34,220,297 34,322,190 RGD:6907045
RGD:13432145
G Apc2 APC regulator of WNT signaling pathway 2 JBrowse link 10 80,295,949 80,318,257 RGD:6907045
G Araf Araf proto-oncogene, serine/threonine kinase JBrowse link X 20,797,707 20,860,521 RGD:6907045
G Axin1 axin 1 JBrowse link 17 26,131,217 26,195,811 RGD:6907045
G Axin2 axin 2 JBrowse link 11 108,917,828 108,950,783 RGD:6907045
RGD:13432159
G Bad BCL2-associated agonist of cell death JBrowse link 19 6,941,861 6,951,905 RGD:6907045
RGD:13432162
G Braf Braf transforming gene JBrowse link 6 39,603,231 39,725,658 RGD:6907045
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6907045
RGD:13432196
G Ccnd1 cyclin D1 JBrowse link 7 144,929,931 144,939,937 RGD:6907045
G Cdh1 cadherin 1 JBrowse link 8 106,603,350 106,670,247 RGD:6907045
G Ctnna1 catenin (cadherin associated protein), alpha 1 JBrowse link 18 35,118,902 35,254,776 RGD:6907045
G Ctnna2 catenin (cadherin associated protein), alpha 2 JBrowse link 6 76,881,637 77,979,815 RGD:6907045
G Ctnna3 catenin (cadherin associated protein), alpha 3 JBrowse link 10 63,430,098 65,003,667 RGD:6907045
G Ctnnb1 catenin (cadherin associated protein), beta 1 JBrowse link 9 120,933,400 120,960,507 RGD:4143515
RGD:6907045
G Egf epidermal growth factor JBrowse link 3 129,677,574 129,755,322 RGD:6907045
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:6907045
G Elk1 ELK1, member of ETS oncogene family JBrowse link X 20,933,395 20,950,608 RGD:6907045
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 11 98,412,484 98,437,716 RGD:4143515
RGD:6907045
G Foxo3 forkhead box O3 JBrowse link 10 42,181,845 42,276,839 RGD:6907045
G Grb2 growth factor receptor bound protein 2 JBrowse link 11 115,644,045 115,708,597 RGD:6907045
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 16 38,089,001 38,246,084 RGD:6907045
G Hras Harvey rat sarcoma virus oncogene JBrowse link 7 141,189,934 141,194,019 RGD:6907045
G Ilk integrin linked kinase JBrowse link 7 105,736,590 105,742,925 RGD:6907045
G Kras Kirsten rat sarcoma viral oncogene homolog JBrowse link 6 145,216,699 145,250,420 RGD:4143515
RGD:6907045
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 3 131,110,277 131,224,357 RGD:6907045
G Map2k1 mitogen-activated protein kinase kinase 1 JBrowse link 9 64,185,769 64,253,605 RGD:6907045
G Map2k2 mitogen-activated protein kinase kinase 2 JBrowse link 10 81,105,913 81,124,697 RGD:6907045
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6907045
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6907045
G Mlh1 mutL homolog 1 JBrowse link 9 111,228,228 111,271,786 RGD:4143515
RGD:6907045
G Msh6 mutS homolog 6 JBrowse link 17 87,975,050 87,990,892 RGD:4143515
G Myc myelocytomatosis oncogene JBrowse link 15 61,985,341 61,990,361 RGD:6907045
G Nras neuroblastoma ras oncogene JBrowse link 3 103,058,285 103,067,914 RGD:6907045
G Pdpk1 3-phosphoinositide dependent protein kinase 1 JBrowse link 17 24,073,680 24,155,619 RGD:6907045
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,059 32,468,486 RGD:4143515
RGD:6907045
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta JBrowse link 9 99,038,402 99,140,235 RGD:6907045
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta JBrowse link 4 149,649,168 149,702,566 RGD:6907045
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 12 32,173,397 32,208,677 RGD:6907045
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 13 101,680,761 101,768,217 RGD:6907045
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 8 70,768,176 70,776,712 RGD:6907045
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 JBrowse link 4 116,221,400 116,303,056 RGD:6907045
G Pik3r5 phosphoinositide-3-kinase regulatory subunit 5 JBrowse link 11 68,432,125 68,497,849 RGD:6907045
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:4143515
RGD:6907045
G Raf1 v-raf-leukemia viral oncogene 1 JBrowse link 6 115,618,569 115,676,635 RGD:6907045
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 17 80,393,752 80,480,453 RGD:6907045
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 12 69,583,761 69,681,852 RGD:6907045
G Tcf7 transcription factor 7, T cell specific JBrowse link 11 52,246,527 52,283,383 RGD:6907045
G Tcf7l1 transcription factor 7 like 1 (T cell specific, HMG box) JBrowse link 6 72,626,371 72,789,045 RGD:6907045
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box JBrowse link 19 55,741,797 55,933,659 RGD:6907045
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:4143515
RGD:6907045

Term paths to the root
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Term Annotations click to browse term
  pathway 6011
    disease pathway 2078
      cancer pathway 390
        urogenital cancer pathway 167
          endometrial cancer pathway 53
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.