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ONTOLOGY REPORT - ANNOTATIONS


Term:endometrial cancer pathway
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Accession:PW:0000611 term browser browse the term
Definition:Endometrial cancer affects the lining of the uterus, or endometrium. Hormonal and genetic alterations play a role in the development of this carcinoma type. Mutations in genes acting in several pathways have been associated with the condition and its types.
Synonyms:related_synonym: KEGG:05213;   endometrial neoplasm pathway

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endometrial cancer pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 RGD:9068941
G AKT2 AKT serine/threonine kinase 2 JBrowse link 6 48,555,785 48,620,472 RGD:9068941
G AKT3 AKT serine/threonine kinase 3 JBrowse link 10 16,441,465 16,741,745 RGD:9068941
G APC APC regulator of WNT signaling pathway JBrowse link 2 116,913,354 116,985,303 RGD:9068941
G APC2 APC regulator of WNT signaling pathway 2 JBrowse link 2 77,005,706 77,034,583 RGD:9068941
G ARAF A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 42,078,202 42,090,250 RGD:9068941
G AXIN1 axin 1 JBrowse link 3 41,344,908 41,393,999 RGD:9068941
G AXIN2 axin 2 JBrowse link 12 12,311,293 12,343,207 RGD:9068941
G BAD BCL2 associated agonist of cell death JBrowse link 2 7,831,192 7,842,864 RGD:9068941
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 18 8,957,963 9,132,558 RGD:9068941
G CASP9 caspase 9 JBrowse link 6 74,707,597 74,730,033 RGD:9068941
G CCND1 cyclin D1 JBrowse link 2 3,621,242 3,633,380 RGD:9068941
G CDH1 cadherin 1 JBrowse link 6 18,075,487 18,155,986 RGD:9068941
G CTNNA1 catenin alpha 1 JBrowse link 2 140,682,776 140,869,828 RGD:9068941
G CTNNA2 catenin alpha 2 JBrowse link 3 63,205,073 64,417,990 RGD:9068941
G CTNNA3 catenin alpha 3 JBrowse link 14 69,195,231 70,974,543 RGD:9068941
G CTNNB1 catenin beta 1 JBrowse link 13 25,163,550 25,208,314 RGD:9068941
G EGF epidermal growth factor JBrowse link 8 112,235,607 112,330,062 RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 9 139,302,410 139,474,632 RGD:9068941
G ELK1 ETS transcription factor ELK1 JBrowse link X 42,157,980 42,174,964 RGD:9068941
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 12 22,591,621 22,621,384 RGD:9068941
G FOXO3 forkhead box O3 JBrowse link 1 74,626,673 74,760,323 RGD:9068941
G GRB2 growth factor receptor bound protein 2 JBrowse link 12 5,940,723 6,009,095 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 13 140,136,109 140,370,197 RGD:9068941
G HRAS HRas proto-oncogene, GTPase JBrowse link 2 299,662 302,539 RGD:9068941
G ILK integrin linked kinase JBrowse link 9 3,145,647 3,152,097 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 5 48,508,774 48,546,260 RGD:9068941
G LEF1 lymphoid enhancer binding factor 1 JBrowse link 8 113,824,511 113,944,078 RGD:9068941
G LOC100511937 phosphatidylinositol 3-kinase regulatory subunit gamma JBrowse link 6 165,268,260 165,402,668 RGD:9068941
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 1 164,381,892 164,469,313 RGD:9068941
G MAP2K2 mitogen-activated protein kinase kinase 2 JBrowse link 2 74,626,739 74,651,352 RGD:9068941
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 14 50,083,079 50,165,528 RGD:9068941
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 3 18,291,444 18,299,410 RGD:9068941
G MLH1 mutL homolog 1 JBrowse link 13 21,791,276 21,877,789 RGD:9068941
G MSH6 mutS homolog 6 JBrowse link 3 92,792,590 92,814,154 RGD:9068941
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 4 12,455,141 12,460,360 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 4 105,845,913 105,853,769 RGD:9068941
G PDPK1 3-phosphoinositide dependent protein kinase 1 JBrowse link 3 39,429,928 39,512,623 RGD:9068941
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 13 117,193,935 117,282,151 RGD:9068941
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta JBrowse link 13 79,427,033 79,610,840 RGD:9068941
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta JBrowse link 6 70,026,254 70,086,950 RGD:9068941
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 9 106,698,200 106,748,217 RGD:9068941
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 16 46,434,757 46,523,626 RGD:9068941
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 2 59,637,363 59,652,075 RGD:9068941
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 JBrowse link 12 53,979,206 54,046,927 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 14 99,929,590 100,021,619 RGD:9068941
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 13 68,581,128 68,657,911 RGD:9068941
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 3 101,209,568 101,366,057 RGD:9068941
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 1 179,907,578 180,014,941 RGD:9068941
G TCF7 transcription factor 7 JBrowse link 2 136,422,740 136,456,323 RGD:9068941
G TCF7L1 transcription factor 7 like 1 JBrowse link 3 59,438,152 59,458,988 RGD:9068941
G TCF7L2 transcription factor 7 like 2 JBrowse link 14 123,343,695 123,547,332 RGD:9068941
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:9068941

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  pathway 5635
    disease pathway 1907
      cancer pathway 383
        urogenital cancer pathway 165
          endometrial cancer pathway 53
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.