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ONTOLOGY REPORT - ANNOTATIONS


Term:retinoic acid metabolic pathway
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Accession:PW:0001004 term browser browse the term
Definition:The reactions involved in deriving retinoic acid (RA) from retinal and its further processing to more polar derivatives. Retinoic acid engages several retinoic acid receptors; its actions are important for the neuro and immune system functions and energy balance. Deregulation of proper RA activity has been associated with obesity and cancer.
Synonyms:exact_synonym: RA metabolic pathway

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retinoic acid metabolic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:6484672
RGD:6771354
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:6484672
RGD:6771354
RGD:6771322
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 JBrowse link 1 127,302,920 127,337,828 RGD:6484672
RGD:6771354
RGD:6771322
G Crabp1 cellular retinoic acid binding protein 1 JBrowse link 8 59,344,097 59,352,135 RGD:6484672
G Crabp2 cellular retinoic acid binding protein 2 JBrowse link 2 187,322,416 187,326,794 RGD:6484672
RGD:6771322
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:6484672
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 JBrowse link 4 116,261,796 116,278,615 RGD:6484672
RGD:6771354
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 JBrowse link 1 256,369,410 256,380,649 RGD:6484672
G Dhrs9 dehydrogenase/reductase 9 JBrowse link 3 55,623,671 55,645,883 RGD:6484672
RGD:6771354
RGD:6771322
G Fabp5 fatty acid binding protein 5 JBrowse link 2 93,981,662 93,985,322 RGD:6484672
G Lrat lecithin retinol acyltransferase JBrowse link 2 181,896,304 181,905,366 RGD:6484672
G Rbp1 retinol binding protein 1 JBrowse link 8 106,449,321 106,470,842 RGD:6484672
RGD:6771322
G Rbp4 retinol binding protein 4 JBrowse link 1 256,806,476 256,813,678 RGD:6484671
RGD:6484672
G Rdh10 retinol dehydrogenase 10 JBrowse link 5 2,605,265 2,631,905 RGD:6484672
RGD:6771354
G Rdh16 retinol dehydrogenase 16 JBrowse link 7 71,058,150 71,072,685 RGD:6771354
G Rdh7 retinol dehydrogenase 7 JBrowse link 7 71,125,358 71,164,014 RGD:6484672
G Stra6 signaling receptor and transporter of retinol STRA6 JBrowse link 8 62,925,364 62,944,438 RGD:6484671
RGD:6484672
G Ttr transthyretin JBrowse link 18 15,532,963 15,542,180 RGD:6484671

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6016
    classic metabolic pathway 1851
      metabolic pathway of cofactors, vitamins, nutrients 367
        retinoid metabolic pathway 96
          retinoic acid metabolic pathway 18
Path 2
Term Annotations click to browse term
  pathway 6016
    regulatory pathway 3823
      homeostasis pathway 1751
        organic chemical homeostasis pathway 429
          vitamin homeostasis 146
            vitamin A homeostasis 146
              retinoid metabolic pathway 96
                retinoic acid metabolic pathway 18
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.