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ONTOLOGY REPORT - ANNOTATIONS


Term:toxoplasmosis pathway
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Accession:PW:0001052 term browser browse the term
Definition:Toxoplasma gondii, whose hosts include various warm-blooded species including humans, is the causative agent of toxoplasmosis. The infection interferes with a number of host pathways; in its most severe manifestations it can be fatal.
Synonyms:exact_synonym: Toxoplasma gondii infection pathway
 related_synonym: KEGG:05145


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toxoplasmosis pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6907045
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:6907045
G Akt3 AKT serine/threonine kinase 3 JBrowse link 13 95,076,308 95,348,913 RGD:6907045
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:6907045
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:6907045
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6907045
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6907045
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:6907045
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:6907045
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6907045
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6907045
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6907045
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:6907045
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:6907045
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:6907045
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6907045
G Ciita class II, major histocompatibility complex, transactivator JBrowse link 10 5,212,621 5,260,641 RGD:6907045
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:6907045
G Cyct cytochrome c, testis JBrowse link 3 63,204,779 63,211,847 RGD:6907045
G Gnai1 G protein subunit alpha i1 JBrowse link 4 13,405,136 13,486,866 RGD:6907045
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:6907045
G Gnai3 G protein subunit alpha i3 JBrowse link 2 210,896,779 210,934,733 RGD:6907045
G Gnao1 G protein subunit alpha o1 JBrowse link 19 11,513,201 11,669,578 RGD:6907045
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6907045
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:6907045
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:6907045
G Hspa2 heat shock protein family A (Hsp70) member 2 JBrowse link 6 99,433,575 99,436,288 RGD:6907045
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6907045
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6907045
G Ifngr1 interferon gamma receptor 1 JBrowse link 1 15,062,380 15,080,815 RGD:6907045
G Ifngr2 interferon gamma receptor 2 JBrowse link 11 31,694,339 31,712,611 RGD:6907045
G Igtp interferon gamma induced GTPase JBrowse link 10 43,631,089 43,639,044 RGD:6907045
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:6907045
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:6907045
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6907045
G Il10ra interleukin 10 receptor subunit alpha JBrowse link 8 49,558,062 49,573,891 RGD:6907045
G Il10rb interleukin 10 receptor subunit beta JBrowse link 11 31,560,301 31,582,457 RGD:6907045
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:6907045
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:6907045
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 156,716,469 156,726,367 RGD:6907045
G Irak4 interleukin-1 receptor-associated kinase 4 JBrowse link 7 135,803,723 135,831,006 RGD:6907045
G Itga6 integrin subunit alpha 6 JBrowse link 3 58,442,904 58,515,124 RGD:6907045
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:6907045
G Jak1 Janus kinase 1 JBrowse link 5 119,982,503 120,091,452 RGD:6907045
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:6907045
G Lama1 laminin subunit alpha 1 JBrowse link 9 115,916,907 116,042,123 RGD:6907045
G Lama2 laminin subunit alpha 2 JBrowse link 1 18,491,264 19,143,486 RGD:6907045
G Lama5 laminin subunit alpha 5 JBrowse link 3 175,553,042 175,601,112 RGD:6907045
G Lamb2 laminin subunit beta 2 JBrowse link 8 117,268,335 117,280,517 RGD:6907045
G Lamb3 laminin subunit beta 3 JBrowse link 13 112,031,614 112,073,187 RGD:6907045
G Lamc1 laminin subunit gamma 1 JBrowse link 13 70,656,727 70,783,515 RGD:6907045
G Lamc2 laminin subunit gamma 2 JBrowse link 13 70,566,643 70,632,126 RGD:6907045
G Lamc3 laminin subunit gamma 3 JBrowse link 3 9,265,407 9,327,107 RGD:6907045
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:6907045
G Ly96 lymphocyte antigen 96 JBrowse link 5 1,972,212 1,989,448 RGD:6907045
G Map2k3 mitogen activated protein kinase kinase 3 JBrowse link 10 45,089,455 45,110,802 RGD:6907045
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:6907045
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:6907045
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6907045
G Mapk10 mitogen activated protein kinase 10 JBrowse link 14 8,079,955 8,371,508 RGD:6907045
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:6907045
G Mapk12 mitogen-activated protein kinase 12 JBrowse link 7 130,109,214 130,120,918 RGD:6907045
G Mapk13 mitogen activated protein kinase 13 JBrowse link 20 6,018,374 6,027,467 RGD:6907045
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6907045
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6907045
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6907045
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:6907045
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:6907045
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6907045
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6907045
G Nfkbib NFKB inhibitor beta JBrowse link 1 86,941,073 86,948,845 RGD:6907045
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6907045
G Pdk1 pyruvate dehydrogenase kinase 1 JBrowse link 3 58,530,870 58,561,494 RGD:6907045
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:6907045
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta JBrowse link 8 107,275,849 107,381,088 RGD:6907045
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta JBrowse link 5 166,602,053 166,628,028 RGD:6907045
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:6907045
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 16 20,415,109 20,424,982 RGD:6907045
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 JBrowse link 5 135,069,972 135,145,633 RGD:6907045
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 JBrowse link 10 55,013,686 55,078,986 RGD:6907045
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:6907045
G Pla2g12a phospholipase A2, group XIIA JBrowse link 2 235,311,664 235,327,972 RGD:6907045
G Pla2g12b phospholipase A2, group XIIB JBrowse link 20 28,989,440 29,007,967 RGD:6907045
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:6907045
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:6907045
G Pla2g2c phospholipase A2, group IIC JBrowse link 5 157,163,672 157,187,654 RGD:6907045
G Pla2g2d phospholipase A2, group IID JBrowse link 5 157,222,636 157,228,795 RGD:6907045
G Pla2g2f phospholipase A2, group IIF JBrowse link 5 157,192,047 157,217,265 RGD:6907045
G Pla2g3 phospholipase A2, group III JBrowse link 14 83,724,828 83,730,614 RGD:6907045
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:6907045
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:6907045
G Pla2g4e phospholipase A2, group IVE JBrowse link 3 111,952,396 112,018,470 RGD:6907045
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:6907045
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:6907045
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:6907045
G Ppif peptidylprolyl isomerase F JBrowse link 16 1,979,191 1,985,912 RGD:6907045
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6907045
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:6907045
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:6907045
G RT1-Da RT1 class II, locus Da JBrowse link 20 4,127,644 4,132,616 RGD:6907045
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:6907045
G RT1-DMa RT1 class II, locus DMa JBrowse link 20 3,935,512 3,938,915 RGD:6907045
G RT1-DMb RT1 class II, locus DMb JBrowse link 20 3,945,383 3,952,838 RGD:6907045
G RT1-DOa RT1 class II, locus DOa JBrowse link 20 3,889,106 3,892,360 RGD:6907045
G RT1-DOb RT1 class II, locus DOb JBrowse link 20 4,020,273 4,026,398 RGD:6907045
G RT1-Ha RT1 class II, locus Ha JBrowse link 20 3,875,478 3,885,140 RGD:6907045
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:6907045
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:6907045
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6907045
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6907045
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:6907045
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:6907045
G Tlr11 toll-like receptor 11 JBrowse link 15 27,177,900 27,182,339 RGD:6907045
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:6907045
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:6907045
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6907045
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:6907045
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:6907045
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:6907045

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  pathway 6016
    disease pathway 1947
      infectious disease pathway 551
        toxoplasmosis pathway 119
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.