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ONTOLOGY REPORT - ANNOTATIONS


Term:toxoplasmosis pathway
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Accession:PW:0001052 term browser browse the term
Definition:Toxoplasma gondii, whose hosts include various warm-blooded species including humans, is the causative agent of toxoplasmosis. The infection interferes with a number of host pathways; in its most severe manifestations it can be fatal.
Synonyms:exact_synonym: Toxoplasma gondii infection pathway
 related_synonym: KEGG:05145


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toxoplasmosis pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6907045
G AKT2 AKT serine/threonine kinase 2 JBrowse link 19 40,230,317 40,285,531 RGD:6907045
G AKT3 AKT serine/threonine kinase 3 JBrowse link 1 243,488,233 243,851,079 RGD:6907045
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 10 45,374,166 45,446,121 RGD:6907045
G BAD BCL2 associated agonist of cell death JBrowse link 11 64,269,828 64,284,704 RGD:6907045
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6907045
G BCL2L1 BCL2 like 1 JBrowse link 20 31,664,452 31,723,963 RGD:6907045
G BIRC2 baculoviral IAP repeat containing 2 JBrowse link 11 102,347,182 102,378,670 RGD:6907045
G BIRC3 baculoviral IAP repeat containing 3 JBrowse link 11 102,317,373 102,339,403 RGD:6907045
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6907045
G CASP8 caspase 8 JBrowse link 2 201,233,443 201,287,711 RGD:6907045
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6907045
G CCR5 C-C motif chemokine receptor 5 (gene/pseudogene) JBrowse link 3 46,370,142 46,376,206 RGD:6907045
G CD40 CD40 molecule JBrowse link 20 46,118,242 46,129,858 RGD:6907045
G CD40LG CD40 ligand JBrowse link X 136,648,158 136,660,390 RGD:6907045
G CHUK component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 10 100,188,298 100,229,610 RGD:6907045
G CIITA class II major histocompatibility complex transactivator JBrowse link 16 10,866,208 10,941,562 RGD:6907045
G CYCS cytochrome c, somatic JBrowse link 7 25,118,656 25,125,260 RGD:6907045
G GNAI1 G protein subunit alpha i1 JBrowse link 7 80,134,831 80,226,181 RGD:6907045
G GNAI2 G protein subunit alpha i2 JBrowse link 3 50,227,068 50,259,362 RGD:6907045
G GNAI3 G protein subunit alpha i3 JBrowse link 1 109,548,615 109,600,195 RGD:6907045
G GNAO1 G protein subunit alpha o1 JBrowse link 16 56,191,489 56,357,444 RGD:6907045
G HLA-DMA major histocompatibility complex, class II, DM alpha JBrowse link 6 32,948,618 32,953,097 RGD:6907045
G HLA-DMB major histocompatibility complex, class II, DM beta JBrowse link 6 32,934,636 32,941,028 RGD:6907045
G HLA-DOA major histocompatibility complex, class II, DO alpha JBrowse link 6 33,004,182 33,009,591 RGD:6907045
G HLA-DOB major histocompatibility complex, class II, DO beta JBrowse link 6 32,812,763 32,817,002 RGD:6907045
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 JBrowse link 6 33,064,569 33,080,748 RGD:6907045
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 JBrowse link 6 33,075,990 33,089,696 RGD:6907045
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 JBrowse link 6 32,637,406 32,654,846 RGD:6907045
G HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 JBrowse link 6 32,741,391 32,747,198 RGD:6907045
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 JBrowse link 6 32,659,467 32,666,657 RGD:6907045
G HLA-DRA major histocompatibility complex, class II, DR alpha JBrowse link 6 32,439,887 32,445,046 RGD:6907045
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 JBrowse link 6 32,578,769 32,589,836 RGD:6907045
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 RGD:6907045
G HLA-DRB4 major histocompatibility complex, class II, DR beta 4 RGD:6907045
G HLA-DRB5 major histocompatibility complex, class II, DR beta 5 JBrowse link 6 32,517,343 32,530,316 RGD:6907045
G HSPA1A heat shock protein family A (Hsp70) member 1A JBrowse link 6 31,815,543 31,817,942 RGD:6907045
G HSPA1B heat shock protein family A (Hsp70) member 1B JBrowse link 6 31,827,738 31,830,254 RGD:6907045
G HSPA1L heat shock protein family A (Hsp70) member 1 like JBrowse link 6 31,809,619 31,815,283 RGD:6907045
G HSPA2 heat shock protein family A (Hsp70) member 2 JBrowse link 14 64,540,468 64,543,237 RGD:6907045
G HSPA6 heat shock protein family A (Hsp70) member 6 JBrowse link 1 161,524,540 161,526,894 RGD:6907045
G HSPA8 heat shock protein family A (Hsp70) member 8 JBrowse link 11 123,057,489 123,062,366 RGD:6907045
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:6907045
G IFNGR1 interferon gamma receptor 1 JBrowse link 6 137,197,484 137,220,351 RGD:6907045
G IFNGR2 interferon gamma receptor 2 JBrowse link 21 33,402,896 33,437,521 RGD:6907045
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 8 42,270,727 42,332,653 RGD:6907045
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 154,542,212 154,565,046 RGD:6907045
G IL10 interleukin 10 JBrowse link 1 206,767,602 206,772,494 RGD:6907045
G IL10RA interleukin 10 receptor subunit alpha JBrowse link 11 117,986,394 118,003,037 RGD:6907045
G IL10RB interleukin 10 receptor subunit beta JBrowse link 21 33,266,367 33,297,221 RGD:6907045
G IL12A interleukin 12A JBrowse link 3 159,988,835 159,996,019 RGD:6907045
G IL12B interleukin 12B JBrowse link 5 159,314,780 159,330,487 RGD:6907045
G IRAK1 interleukin 1 receptor associated kinase 1 JBrowse link X 154,010,507 154,019,984 RGD:6907045
G IRAK4 interleukin 1 receptor associated kinase 4 JBrowse link 12 43,758,909 43,789,543 RGD:6907045
G IRGM immunity related GTPase M JBrowse link 5 150,846,521 150,902,402 RGD:6907045
G ITGA6 integrin subunit alpha 6 JBrowse link 2 172,427,336 172,506,459 RGD:6907045
G ITGB1 integrin subunit beta 1 JBrowse link 10 32,900,318 32,958,230 RGD:6907045
G JAK1 Janus kinase 1 JBrowse link 1 64,833,223 65,067,746 RGD:6907045
G JAK2 Janus kinase 2 JBrowse link 9 4,985,086 5,129,948 RGD:6907045
G JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough JBrowse link 15 41,828,085 41,848,148 RGD:6907045
G LAMA1 laminin subunit alpha 1 JBrowse link 18 6,941,742 7,117,797 RGD:6907045
G LAMA2 laminin subunit alpha 2 JBrowse link 6 128,883,138 129,516,566 RGD:6907045
G LAMA3 laminin subunit alpha 3 JBrowse link 18 23,689,443 23,956,222 RGD:6907045
G LAMA4 laminin subunit alpha 4 JBrowse link 6 112,107,931 112,254,722 RGD:6907045
G LAMA5 laminin subunit alpha 5 JBrowse link 20 62,309,060 62,367,318 RGD:6907045
G LAMB1 laminin subunit beta 1 JBrowse link 7 107,923,799 108,003,176 RGD:6907045
G LAMB2 laminin subunit beta 2 JBrowse link 3 49,121,114 49,133,066 RGD:6907045
G LAMB3 laminin subunit beta 3 JBrowse link 1 209,614,870 209,652,467 RGD:6907045
G LAMB4 laminin subunit beta 4 JBrowse link 7 108,011,662 108,130,361 RGD:6907045
G LAMC1 laminin subunit gamma 1 JBrowse link 1 183,023,420 183,145,592 RGD:6907045
G LAMC2 laminin subunit gamma 2 JBrowse link 1 183,186,264 183,245,127 RGD:6907045
G LAMC3 laminin subunit gamma 3 JBrowse link 9 131,009,174 131,094,473 RGD:6907045
G LDLR low density lipoprotein receptor JBrowse link 19 11,089,432 11,133,820 RGD:6907045
G LY96 lymphocyte antigen 96 JBrowse link 8 73,991,275 74,099,807 RGD:6907045
G MAP2K3 mitogen-activated protein kinase kinase 3 JBrowse link 17 21,284,679 21,315,240 RGD:6907045
G MAP2K6 mitogen-activated protein kinase kinase 6 JBrowse link 17 69,414,697 69,553,865 RGD:6907045
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 JBrowse link 6 90,513,579 90,587,072 RGD:6907045
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6907045
G MAPK10 mitogen-activated protein kinase 10 JBrowse link 4 86,010,405 86,594,625 RGD:6907045
G MAPK11 mitogen-activated protein kinase 11 JBrowse link 22 50,263,713 50,270,380 RGD:6907045
G MAPK12 mitogen-activated protein kinase 12 JBrowse link 22 50,252,901 50,261,810 RGD:6907045
G MAPK13 mitogen-activated protein kinase 13 JBrowse link 6 36,130,513 36,144,521 RGD:6907045
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 6 36,027,677 36,122,964 RGD:6907045
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6907045
G MAPK8 mitogen-activated protein kinase 8 JBrowse link 10 48,306,639 48,439,360 RGD:6907045
G MAPK9 mitogen-activated protein kinase 9 JBrowse link 5 180,233,143 180,292,083 RGD:6907045
G MYD88 MYD88 innate immune signal transduction adaptor JBrowse link 3 38,138,661 38,143,022 RGD:6907045
G NFKB1 nuclear factor kappa B subunit 1 JBrowse link 4 102,501,266 102,617,302 RGD:6907045
G NFKBIA NFKB inhibitor alpha JBrowse link 14 35,401,513 35,404,749 RGD:6907045
G NFKBIB NFKB inhibitor beta JBrowse link 19 38,899,503 38,908,894 RGD:6907045
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6907045
G PDK1 pyruvate dehydrogenase kinase 1 JBrowse link 2 172,555,373 172,672,698 RGD:6907045
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 179,148,114 179,240,093 RGD:6907045
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta JBrowse link 3 138,652,698 138,834,928 RGD:6907045
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta JBrowse link 1 9,629,889 9,729,114 RGD:6907045
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 7 106,865,282 106,908,980 RGD:6907045
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 5 68,215,737 68,301,821 RGD:6907045
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 19 18,153,163 18,170,532 RGD:6907045
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 JBrowse link 1 46,040,140 46,174,901 RGD:6907045
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 JBrowse link 17 8,878,916 8,965,712 RGD:6907045
G PLA2G10 phospholipase A2 group X JBrowse link 16 14,672,548 14,694,662 RGD:6907045
G PLA2G12A phospholipase A2 group XIIA JBrowse link 4 109,709,989 109,730,070 RGD:6907045
G PLA2G12B phospholipase A2 group XIIB JBrowse link 10 72,934,762 72,955,044 RGD:6907045
G PLA2G1B phospholipase A2 group IB JBrowse link 12 120,322,115 120,327,779 RGD:6907045
G PLA2G2A phospholipase A2 group IIA JBrowse link 1 19,975,431 19,980,434 RGD:6907045
G PLA2G2C phospholipase A2 group IIC JBrowse link 1 20,163,055 20,177,439 RGD:6907045
G PLA2G2D phospholipase A2 group IID JBrowse link 1 20,111,939 20,119,566 RGD:6907045
G PLA2G2E phospholipase A2 group IIE JBrowse link 1 19,920,009 19,923,617 RGD:6907045
G PLA2G2F phospholipase A2 group IIF JBrowse link 1 20,139,323 20,150,386 RGD:6907045
G PLA2G3 phospholipase A2 group III JBrowse link 22 31,134,807 31,140,508 RGD:6907045
G PLA2G4A phospholipase A2 group IVA JBrowse link 1 186,828,900 186,988,981 RGD:6907045
G PLA2G4B phospholipase A2 group IVB JBrowse link 15 41,838,813 41,848,148 RGD:6907045
G PLA2G4E phospholipase A2 group IVE JBrowse link 15 41,981,582 42,050,703 RGD:6907045
G PLA2G5 phospholipase A2 group V JBrowse link 1 20,028,349 20,091,911 RGD:6907045
G PLA2G6 phospholipase A2 group VI JBrowse link 22 38,111,495 38,181,830 RGD:6907045
G PPIF peptidylprolyl isomerase F JBrowse link 10 79,347,469 79,355,334 RGD:6907045
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6907045
G SOCS1 suppressor of cytokine signaling 1 JBrowse link 16 11,254,417 11,256,182 RGD:6907045
G STAT1 signal transducer and activator of transcription 1 JBrowse link 2 190,968,989 191,014,250 RGD:6907045
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 42,313,324 42,388,502 RGD:6907045
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 JBrowse link 22 39,399,780 39,437,132 RGD:6907045
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 JBrowse link 6 149,217,924 149,411,613 RGD:6907045
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6907045
G TGFB2 transforming growth factor beta 2 JBrowse link 1 218,345,284 218,444,619 RGD:6907045
G TGFB3 transforming growth factor beta 3 JBrowse link 14 75,958,061 75,983,011 RGD:6907045
G TLR2 toll like receptor 2 JBrowse link 4 153,684,080 153,710,643 RGD:6907045
G TLR4 toll like receptor 4 JBrowse link 9 117,704,403 117,724,735 RGD:6907045
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6907045
G TNFRSF1A TNF receptor superfamily member 1A JBrowse link 12 6,328,771 6,342,076 RGD:6907045
G TRAF6 TNF receptor associated factor 6 JBrowse link 11 36,483,769 36,510,313 RGD:6907045
G TYK2 tyrosine kinase 2 JBrowse link 19 10,350,528 10,380,572 RGD:6907045
G XIAP X-linked inhibitor of apoptosis JBrowse link X 123,859,812 123,913,979 RGD:6907045

Term paths to the root
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  pathway 5944
    disease pathway 2071
      infectious disease pathway 642
        toxoplasmosis pathway 132
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.