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ONTOLOGY REPORT - ANNOTATIONS


Term:histone modification pathway
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Accession:PW:0001338 term browser browse the term
Definition:The tails of histone proteins are subject to a wide array of modifications of which methylation and acetylation have been more thoroughly documented. The modified residues are recognized by particular proteins or readers, in turn acting upon their targets. The modifications are rendered reversible by the enzymes that carry out the reaction in the opposite direction, also referred to as erasers.

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Path 1
Term Annotations click to browse term
  pathway 2314
    regulatory pathway 976
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 404
        chromatin modification/remodeling pathway 1
          chromatin modification pathway 1
            histone modification pathway 0
              altered histone modification pathway 0
Path 2
Term Annotations click to browse term
  pathway 2314
    regulatory pathway 976
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 404
        DNA damage response pathway 12
          DNA repair pathway 12
            chromatin modification/remodeling pathway 1
              chromatin modification pathway 1
                histone modification pathway 0
                  altered histone modification pathway 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.