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ONTOLOGY REPORT - ANNOTATIONS


Term:antithrombotic drug pathway
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Accession:PW:0001651 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: anticoagulant drug pathway


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abciximab pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itga2b integrin subunit alpha 2b JBrowse link 10 90,397,960 90,416,550 RGD:10402751
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:10402751
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:10402751
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:10402751
G Alox12b arachidonate 12-lipoxygenase, 12R type JBrowse link 10 55,744,646 55,756,524 RGD:10402751
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:10402751
G Alox15b arachidonate 15-lipoxygenase, type B JBrowse link 10 55,773,748 55,783,489 RGD:10402751
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:10402751
G Cbr1 carbonyl reductase 1 JBrowse link 11 33,813,041 33,815,418 RGD:10402751
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:10402751
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:10402751
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:10402751
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 JBrowse link 5 119,546,458 119,564,843 RGD:10402751
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 JBrowse link 2 236,414,131 236,431,650 RGD:10402751
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 JBrowse link 16 19,501,680 19,528,935 RGD:10402751
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:10402751
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:10402751
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:10402751
G Lta4h leukotriene A4 hydrolase JBrowse link 7 34,288,333 34,320,243 RGD:10402751
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:10402751
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:10402751
G Prxl2b peroxiredoxin like 2B JBrowse link 5 172,304,799 172,307,402 RGD:10402751
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:10402751
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:10402751
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:10402751
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:10402751
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:10402751
G Tbxas1 thromboxane A synthase 1 JBrowse link 4 66,624,181 66,846,745 RGD:10402751
alteplase pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
anistreplase pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
argatroban pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
cilostazol pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:10402751
clopidogrel pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:10402751
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:10402751
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:10402751
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:10402751
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:10402751
G P2ry12 purinergic receptor P2Y12 JBrowse link 2 149,440,807 149,482,592 RGD:10402751
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:10402751
clopidogrel pharmacokinetics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:10402751
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:10402751
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:10402751
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:10402751
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:10402751
G P2ry12 purinergic receptor P2Y12 JBrowse link 2 149,440,807 149,482,592 RGD:10402751
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:10402751
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
dipyridamole pharmacodyamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:10402751
enoxaparin pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
eptifibatide pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itga2b integrin subunit alpha 2b JBrowse link 10 90,397,960 90,416,550 RGD:10402751
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:10402751
fondaparinux pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
heparin pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
phenindione pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
reteplase pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:10402751
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:10402751
G Alox12b arachidonate 12-lipoxygenase, 12R type JBrowse link 10 55,744,646 55,756,524 RGD:10402751
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:10402751
G Alox15b arachidonate 15-lipoxygenase, type B JBrowse link 10 55,773,748 55,783,489 RGD:10402751
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:10402751
G Cbr1 carbonyl reductase 1 JBrowse link 11 33,813,041 33,815,418 RGD:10402751
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:10402751
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:10402751
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:10402751
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 JBrowse link 5 119,546,458 119,564,843 RGD:10402751
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 JBrowse link 2 236,414,131 236,431,650 RGD:10402751
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 JBrowse link 16 19,501,680 19,528,935 RGD:10402751
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:10402751
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:10402751
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:10402751
G Lta4h leukotriene A4 hydrolase JBrowse link 7 34,288,333 34,320,243 RGD:10402751
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:10402751
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:10402751
G Prxl2b peroxiredoxin like 2B JBrowse link 5 172,304,799 172,307,402 RGD:10402751
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:10402751
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:10402751
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:10402751
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:10402751
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:10402751
G Tbxas1 thromboxane A synthase 1 JBrowse link 4 66,624,181 66,846,745 RGD:10402751
ticlopidine pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G P2ry12 purinergic receptor P2Y12 JBrowse link 2 149,440,807 149,482,592 RGD:10402751
ticlopidine pharmacokinetics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G P2ry12 purinergic receptor P2Y12 JBrowse link 2 149,440,807 149,482,592 RGD:10402751
tirofiban pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itga2b integrin subunit alpha 2b JBrowse link 10 90,397,960 90,416,550 RGD:10402751
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:10402751
warfarin pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:11354881
RGD:10402751

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6016
    drug pathway 393
      blood and blood forming organs drug pathway 56
        antithrombotic drug pathway 56
          anticoagulant drug pathway + 21
          antiplatelet drug pathway + 35
          other antithrombotic drug pathway + 21
          thrombolytic drug pathway + 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.