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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:antihemorrhagic drug pathway
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Accession:PW:0001652 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent bleeding. It is to be noted here that genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: hemostatic drug pathway


show annotations for term's descendants           Sort by:
 
aminocaproic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00286 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00286 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00286 NCBI chr 4:186,265,964...186,290,727
Ensembl chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00286 NCBI chr 5:177,402,138...177,409,564
Ensembl chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,141...177,409,564
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00286 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00286 NCBI chr 1:197,038,741...197,067,264
Ensembl chr 1:197,038,741...197,067,267
Ensembl chr 1:197,038,741...197,067,267
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00286 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00286 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00286 NCBI chr 1:169,511,951...169,586,630
Ensembl chr 1:169,511,951...169,586,588
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00286 NCBI chr13:113,105,773...113,120,685
Ensembl chr13:113,105,788...113,120,681
Ensembl chr13:113,105,788...113,120,681
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00286 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00286 NCBI chr  X:139,530,720...139,563,459
Ensembl chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00286 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00286 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00286 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00286 NCBI chr 2:85,544,720...85,561,527
Ensembl chr 2:85,544,720...85,561,547
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00286 NCBI chr 4:186,215,714...186,258,477
Ensembl chr 4:186,208,979...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00286 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,676
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00286 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,238...160,754,097
Ensembl chr 6:160,702,238...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00286 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
aprotinin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00288 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00288 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00288 NCBI chr 4:186,265,964...186,290,727
Ensembl chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00288 NCBI chr 5:177,402,138...177,409,564
Ensembl chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,141...177,409,564
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00288 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00288 NCBI chr 1:197,038,741...197,067,264
Ensembl chr 1:197,038,741...197,067,267
Ensembl chr 1:197,038,741...197,067,267
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00288 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00288 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00288 NCBI chr 1:169,511,951...169,586,630
Ensembl chr 1:169,511,951...169,586,588
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00288 NCBI chr13:113,105,773...113,120,685
Ensembl chr13:113,105,788...113,120,681
Ensembl chr13:113,105,788...113,120,681
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00288 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00288 NCBI chr  X:139,530,720...139,563,459
Ensembl chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00288 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00288 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00288 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00288 NCBI chr 2:85,544,720...85,561,527
Ensembl chr 2:85,544,720...85,561,547
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00288 NCBI chr 4:186,215,714...186,258,477
Ensembl chr 4:186,208,979...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00288 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,676
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00288 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,238...160,754,097
Ensembl chr 6:160,702,238...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00288 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
tranexamic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00287 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00287 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00287 NCBI chr 4:186,265,964...186,290,727
Ensembl chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00287 NCBI chr 5:177,402,138...177,409,564
Ensembl chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,141...177,409,564
JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00287 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00287 NCBI chr 1:197,038,741...197,067,264
Ensembl chr 1:197,038,741...197,067,267
Ensembl chr 1:197,038,741...197,067,267
JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00287 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00287 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00287 NCBI chr 1:169,511,951...169,586,630
Ensembl chr 1:169,511,951...169,586,588
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00287 NCBI chr13:113,105,773...113,120,685
Ensembl chr13:113,105,788...113,120,681
Ensembl chr13:113,105,788...113,120,681
JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00287 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00287 NCBI chr  X:139,530,720...139,563,459
Ensembl chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459
JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00287 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00287 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00287 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00287 NCBI chr 2:85,544,720...85,561,527
Ensembl chr 2:85,544,720...85,561,547
JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00287 NCBI chr 4:186,215,714...186,258,477
Ensembl chr 4:186,208,979...186,258,471
JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00287 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,676
JBrowse link
G PLG plasminogen EXP SMPDB SMP:00287 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,238...160,754,097
Ensembl chr 6:160,702,238...160,754,097
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00287 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    drug pathway 412
      blood and blood forming organs drug pathway 67
        antihemorrhagic drug pathway 20
          aminocaproic acid drug pathway + 20
          aprotinin drug pathway + 20
          tranexamic acid drug pathway + 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.