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Term:anistreplase pharmacodynamics pathway
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Accession:PW:0001664 term browser browse the term
Definition:The pathway of anistreplase-target interaction and of the biochemical or physiological responses to drug. An anithrombic drug, anistreplase cleaves a bond in plasminogen to form plasmin. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00281

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anistreplase pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link NW_004955451 11,468,156 11,484,410 RGD:9068941
G F10 coagulation factor X JBrowse link NW_004955404 666,142 682,598 RGD:9068941
G F11 coagulation factor XI JBrowse link NW_004955403 22,811,211 22,830,281 RGD:9068941
G F12 coagulation factor XII JBrowse link NW_004955408 29,644,279 29,665,161 RGD:9068941
G F13a1 coagulation factor XIII A chain JBrowse link NW_004955465 7,444,118 7,617,366 RGD:9068941
G F13b coagulation factor XIII B chain JBrowse link NW_004955406 33,633,911 33,660,506 RGD:9068941
G F2 coagulation factor II, thrombin JBrowse link NW_004955422 1,356,675 1,367,788 RGD:9068941
G F3 coagulation factor III, tissue factor JBrowse link NW_004955423 254,060 264,448 RGD:9068941
G F5 coagulation factor V JBrowse link NW_004955462 7,695,004 7,757,832 RGD:9068941
G F7 coagulation factor VII JBrowse link NW_004955404 685,170 692,797 RGD:9068941
G F8 coagulation factor VIII JBrowse link NW_004955594 658,686 800,101 RGD:9068941
G F9 coagulation factor IX JBrowse link NW_004955489 5,747,718 5,780,899 RGD:9068941
G Fga fibrinogen alpha chain JBrowse link NW_004955471 8,806,964 8,814,671 RGD:9068941
G Fgb fibrinogen beta chain JBrowse link NW_004955471 8,824,901 8,832,836 RGD:9068941
G Fgg fibrinogen gamma chain JBrowse link NW_004955471 8,786,910 8,794,947 RGD:9068941
G Ggcx gamma-glutamyl carboxylase JBrowse link NW_004955424 1,926,924 1,952,635 RGD:9068941
G Klkb1 kallikrein B1 JBrowse link NW_004955403 22,835,544 22,856,355 RGD:9068941
G Plat plasminogen activator, tissue type JBrowse link NW_004955536 730,962 754,333 RGD:9068941
G Plg plasminogen JBrowse link NW_004955439 20,317,814 20,366,724 RGD:9068941
G Vkorc1 vitamin K epoxide reductase complex subunit 1 JBrowse link NW_004955493 7,928,516 7,931,265 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 2236
    drug pathway 330
      blood and blood forming organs drug pathway 48
        antithrombotic drug pathway 48
          thrombolytic drug pathway 20
            anistreplase drug pathway 20
              anistreplase pharmacodynamics pathway 20
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.