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The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (

Term:meloxicam pharmacodynamics pathway
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Accession:PW:0001950 term browser browse the term
Definition:The pathway of meloxicam-target interaction and of the biochemical or physiological responses to drug. The drug is a non-selective cyclooxygenase (COX) inhibitor. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00106

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meloxicam pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00106 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,286,019...52,414,907
JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00106 NCBI chr12:53,292,530...53,302,850
Ensembl chr12:53,292,524...53,302,993
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00106 NCBI chr12:52,287,174...52,295,873
Ensembl chr12:52,286,019...52,414,907
JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00106 NCBI chr12:53,259,867...53,281,127
Ensembl chr12:53,259,940...53,281,520
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00106 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,858,975...90,907,094
JBrowse link
G CBR1 carbonyl reductase 1 ISO SMPDB SMP:00106 NCBI chr13:199,617,406...199,622,407
Ensembl chr13:199,617,318...199,622,405
JBrowse link
G CYP2B22 cytochrome P450 2B22 ISO SMPDB SMP:00106 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,413
JBrowse link
G CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 ISO SMPDB SMP:00106 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,818
JBrowse link
G CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 ISO SMPDB SMP:00106 NCBI chr 2:61,745,069...61,759,971 JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00106 NCBI chr14:11,217,125...11,293,018
Ensembl chr14:11,216,977...11,293,412
JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00106 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,914,932...31,917,335
JBrowse link
G LOC100518620 cytochrome P450 2U1 ISO SMPDB SMP:00106 NCBI chr 8:114,016,915...114,035,905
Ensembl chr 8:114,011,304...114,035,357
JBrowse link
G LOC110255237 cytochrome P450 4F6-like ISO SMPDB SMP:00106 NCBI chr 2:61,893,963...61,917,944
Ensembl chr 2:61,889,495...61,917,929
JBrowse link
G LOC110259329 docosahexaenoic acid omega-hydroxylase CYP4F3-like ISO SMPDB SMP:00106 NCBI chr 2:61,863,378...61,884,717
Ensembl chr 2:61,864,575...61,984,903
JBrowse link
G LOC110261221 cytochrome P450 2J2-like ISO SMPDB SMP:00106 NCBI chr 6:152,321,816...152,358,179
Ensembl chr 6:152,321,848...152,648,979
JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00106 NCBI chr 5:87,486,552...87,518,520
Ensembl chr 5:87,486,512...87,518,515
JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00106 NCBI chr 2:78,799,446...78,802,281
Ensembl chr 2:78,799,448...78,802,256
JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00106 NCBI chr 1:129,514,801...129,524,365
Ensembl chr 1:129,514,341...129,533,398
JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00106 NCBI chr 6:64,432,187...64,435,328
Ensembl chr 6:64,432,148...64,435,320
JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00106
G PTGES prostaglandin E synthase ISO SMPDB SMP:00106 NCBI chr 1:269,911,785...269,924,481
Ensembl chr 1:269,911,789...269,924,462
JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00106 NCBI chr17:51,153,151...51,200,515
Ensembl chr17:51,153,154...51,200,300
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00106 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00106 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00106 NCBI chr18:9,717,291...9,886,699
Ensembl chr18:9,717,292...9,886,682
JBrowse link

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  pathway 4028
    drug pathway 385
      musculo-skeletal system drug pathway 64
        meloxicam drug pathway 25
          meloxicam pharmacodynamics pathway 25
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