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ONTOLOGY REPORT - ANNOTATIONS


Term:presequence pathway of mitochondrial protein import
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Accession:PW:0002137 term browser browse the term
Definition:A classical pathway of mitochondrial protein import that delivers matrix resident and some of the inner membrane proteins. The precursor proteins are synthesized with an amino terminal peptide extension - the presequence. Translocase complexes, chaperones and processing enzymes cooperate in the process.


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presequence pathway of mitochondrial protein import term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 JBrowse link 2 120,503,093 120,531,782 RGD:10412659
G Grpel1 GrpE-like 1, mitochondrial JBrowse link 14 79,458,951 79,464,782 RGD:10412659
G Grpel2 GrpE-like 2, mitochondrial JBrowse link 18 57,037,995 57,050,234 RGD:10412659
G Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link 18 27,731,072 27,749,235 RGD:10412659
G Immp1l inner mitochondrial membrane peptidase subunit 1 JBrowse link 3 95,955,126 96,024,316 RGD:10412669
G Immp2l inner mitochondrial membrane peptidase subunit 2 JBrowse link 6 60,958,351 61,859,457 RGD:10412669
G Mipep mitochondrial intermediate peptidase JBrowse link 15 41,084,180 41,192,621 RGD:10412669
G Pam16 presequence translocase associated motor 16 JBrowse link 10 11,146,359 11,153,936 RGD:10412659
G Pmpca peptidase, mitochondrial processing subunit alpha JBrowse link 3 3,834,262 3,842,061 RGD:10412669
G Pmpcb peptidase, mitochondrial processing subunit beta JBrowse link 4 9,908,838 9,921,615 RGD:10412669
G Romo1 reactive oxygen species modulator 1 JBrowse link 3 151,688,213 151,689,813 RGD:10412658
RGD:10412659
G Timm17a translocase of inner mitochondrial membrane 17A JBrowse link 13 52,124,641 52,136,127 RGD:10412658
RGD:10412659
G Timm21 translocase of inner mitochondrial membrane 21 JBrowse link 18 81,803,165 81,807,627 RGD:10412658
RGD:10412659
G Timm23 translocase of inner mitochondrial membrane 23 JBrowse link 16 8,324,038 8,350,067 RGD:10412658
RGD:10412659
G Timm44 translocase of inner mitochondrial membrane 44 JBrowse link 12 2,517,006 2,533,707 RGD:10412659
G Timm50 translocase of inner mitochondrial membrane 50 JBrowse link 1 85,470,810 85,480,813 RGD:10412658
RGD:10412659
G Tomm20 translocase of outer mitochondrial membrane 20 JBrowse link 19 59,863,421 59,873,411 RGD:10412658
RGD:10412659
G Tomm22 translocase of outer mitochondrial membrane 22 JBrowse link 7 120,901,934 120,903,684 RGD:10412658
RGD:10412659
G Tomm40 translocase of outer mitochondrial membrane 40 JBrowse link 1 80,617,749 80,630,253 RGD:10412658
RGD:10412659
G Tomm5 translocase of outer mitochondrial membrane 5 JBrowse link 5 60,655,708 60,658,568 RGD:10412658
RGD:10412659
G Tomm6 translocase of outer mitochondrial membrane 6 JBrowse link 9 15,313,346 15,314,872 RGD:10412658
RGD:10412659
G Tomm7 translocase of outer mitochondrial membrane 7 JBrowse link 4 7,835,949 7,842,790 RGD:10412658
RGD:10412659
G Tomm70 translocase of outer mitochondrial membrane 70 JBrowse link 11 45,477,053 45,511,409 RGD:10412658
RGD:10412659
G Xpnpep3 X-prolyl aminopeptidase 3 JBrowse link 7 122,636,252 122,686,983 RGD:10412669

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  pathway 6064
    regulatory pathway 3843
      homeostasis pathway 1762
        mitochondria homeostasis pathway 112
          mitochondrial protein import pathway 43
            presequence pathway of mitochondrial protein import 24
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.