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ONTOLOGY REPORT - ANNOTATIONS


Term:phenindione pharmacodynamics pathway
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Accession:PW:0002494 term browser browse the term
Definition:The pathway of phenindione-target interaction and of the biochemical or physiological responses to drug. Phenindione is used as anticoagulant that antagonizes the vitamin K dependent clotting pathway. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00655


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phenindione pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G COL1A1 collagen type I alpha 1 chain JBrowse link 17 50,184,096 50,201,649 RGD:10402751
G F10 coagulation factor X JBrowse link 13 113,122,799 113,149,529 RGD:10402751
G F11 coagulation factor XI JBrowse link 4 186,265,964 186,290,727 RGD:10402751
G F12 coagulation factor XII JBrowse link 5 177,402,138 177,409,564 RGD:10402751
G F13A1 coagulation factor XIII A chain JBrowse link 6 6,144,084 6,320,662 RGD:10402751
G F13B coagulation factor XIII B chain JBrowse link 1 197,038,741 197,067,264 RGD:10402751
G F2 coagulation factor II, thrombin JBrowse link 11 46,719,201 46,739,506 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 1 94,529,173 94,541,857 RGD:10402751
G F5 coagulation factor V JBrowse link 1 169,511,951 169,586,630 RGD:10402751
G F7 coagulation factor VII JBrowse link 13 113,105,773 113,120,685 RGD:10402751
G F8 coagulation factor VIII JBrowse link X 154,835,788 155,022,723 RGD:10402751
G F9 coagulation factor IX JBrowse link X 139,530,720 139,563,459 RGD:10402751
G FGA fibrinogen alpha chain JBrowse link 4 154,583,126 154,590,742 RGD:10402751
G FGB fibrinogen beta chain JBrowse link 4 154,562,980 154,572,807 RGD:10402751
G FGG fibrinogen gamma chain JBrowse link 4 154,604,134 154,612,808 RGD:10402751
G GGCX gamma-glutamyl carboxylase JBrowse link 2 85,544,720 85,561,527 RGD:10402751
G KLKB1 kallikrein B1 JBrowse link 4 186,215,714 186,258,477 RGD:10402751
G PLAT plasminogen activator, tissue type JBrowse link 8 42,174,718 42,207,565 RGD:10402751
G PLG plasminogen JBrowse link 6 160,702,193 160,754,097 RGD:10402751
G VKORC1 vitamin K epoxide reductase complex subunit 1 JBrowse link 16 31,090,842 31,094,999 RGD:10402751

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5944
    drug pathway 412
      blood and blood forming organs drug pathway 67
        antithrombotic drug pathway 67
          anticoagulant drug pathway 32
            vitamin K antagonist drug pathway 31
              phenindione drug pathway 20
                phenindione pharmacodynamics pathway 20
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.