Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


Term:phenindione pharmacodynamics pathway
go back to main search page
Accession:PW:0002494 term browser browse the term
Definition:The pathway of phenindione-target interaction and of the biochemical or physiological responses to drug. Phenindione is used as anticoagulant that antagonizes the vitamin K dependent clotting pathway. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00655

show annotations for term's descendants       view all columns           Sort by:
phenindione pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G COL1A1 collagen type I alpha 1 chain JBrowse link 17 50,184,096 50,201,649 RGD:10402751
G F10 coagulation factor X JBrowse link 13 113,122,799 113,149,529 RGD:10402751
G F11 coagulation factor XI JBrowse link 4 186,265,964 186,290,727 RGD:10402751
G F12 coagulation factor XII JBrowse link 5 177,402,138 177,409,564 RGD:10402751
G F13A1 coagulation factor XIII A chain JBrowse link 6 6,144,084 6,320,662 RGD:10402751
G F13B coagulation factor XIII B chain JBrowse link 1 197,038,741 197,067,264 RGD:10402751
G F2 coagulation factor II, thrombin JBrowse link 11 46,719,201 46,739,506 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 1 94,529,173 94,541,857 RGD:10402751
G F5 coagulation factor V JBrowse link 1 169,511,951 169,586,630 RGD:10402751
G F7 coagulation factor VII JBrowse link 13 113,105,773 113,120,685 RGD:10402751
G F8 coagulation factor VIII JBrowse link X 154,835,788 155,022,723 RGD:10402751
G F9 coagulation factor IX JBrowse link X 139,530,720 139,563,459 RGD:10402751
G FGA fibrinogen alpha chain JBrowse link 4 154,583,126 154,590,742 RGD:10402751
G FGB fibrinogen beta chain JBrowse link 4 154,562,980 154,572,807 RGD:10402751
G FGG fibrinogen gamma chain JBrowse link 4 154,604,134 154,612,808 RGD:10402751
G GGCX gamma-glutamyl carboxylase JBrowse link 2 85,544,720 85,561,527 RGD:10402751
G KLKB1 kallikrein B1 JBrowse link 4 186,215,714 186,258,477 RGD:10402751
G PLAT plasminogen activator, tissue type JBrowse link 8 42,174,718 42,207,565 RGD:10402751
G PLG plasminogen JBrowse link 6 160,702,193 160,754,097 RGD:10402751
G VKORC1 vitamin K epoxide reductase complex subunit 1 JBrowse link 16 31,090,842 31,094,999 RGD:10402751

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5944
    drug pathway 412
      blood and blood forming organs drug pathway 67
        antithrombotic drug pathway 67
          anticoagulant drug pathway 32
            vitamin K antagonist drug pathway 31
              phenindione drug pathway 20
                phenindione pharmacodynamics pathway 20
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.