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Term:phenindione pharmacodynamics pathway
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Accession:PW:0002494 term browser browse the term
Definition:The pathway of phenindione-target interaction and of the biochemical or physiological responses to drug. Phenindione is used as anticoagulant that antagonizes the vitamin K dependent clotting pathway. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00655

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phenindione pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen, type I, alpha 1 JBrowse link 11 94,936,224 94,953,042 RGD:10402751
G F10 coagulation factor X JBrowse link 8 13,037,308 13,056,676 RGD:10402751
G F11 coagulation factor XI JBrowse link 8 45,240,659 45,262,055 RGD:10402751
G F12 coagulation factor XII (Hageman factor) JBrowse link 13 55,417,958 55,426,804 RGD:10402751
G F13a1 coagulation factor XIII, A1 subunit JBrowse link 13 36,867,178 37,050,244 RGD:10402751
G F13b coagulation factor XIII, beta subunit JBrowse link 1 139,501,547 139,523,758 RGD:10402751
G F2 coagulation factor II JBrowse link 2 91,612,397 91,636,457 RGD:10402751
G F3 coagulation factor III JBrowse link 3 121,723,537 121,735,052 RGD:10402751
G F5 coagulation factor V JBrowse link 1 164,151,835 164,220,277 RGD:10402751
G F7 coagulation factor VII JBrowse link 8 13,025,506 13,035,809 RGD:10402751
G F8 coagulation factor VIII JBrowse link X 75,170,344 75,382,738 RGD:10402751
G F9 coagulation factor IX JBrowse link X 59,999,329 60,030,760 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 3 83,026,153 83,033,627 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 3 83,042,246 83,049,863 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 3 83,007,724 83,015,056 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 6 72,414,279 72,433,359 RGD:10402751
G Klkb1 kallikrein B, plasma 1 JBrowse link 8 45,266,688 45,294,835 RGD:10402751
G Plat plasminogen activator, tissue JBrowse link 8 22,757,722 22,782,848 RGD:10402751
G Plg plasminogen JBrowse link 17 12,378,609 12,419,384 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 7 127,893,063 127,895,658 RGD:10402751

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6011
    drug pathway 396
      blood and blood forming organs drug pathway 60
        antithrombotic drug pathway 60
          anticoagulant drug pathway 21
            vitamin K antagonist drug pathway 20
              phenindione drug pathway 20
                phenindione pharmacodynamics pathway 20
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.