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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
(-)-beta-caryophyllene 
(2R,3S,2'R)-nadolol +   
(2S)-2-(4-\{[(1R,2S)-2-hydroxycyclopentyl]methyl\}phenyl)propanoic acid 
(E)-3-tosylacrylonitrile 
(R)-adrenaline +   
(S)-ketorolac +   
(S)-timolol (anhydrous) +   
(S)-timolol hemihydrate 
(S)-timolol maleate 
1',3'-dimethylspiro[1H-indole-3,8'-7,9-dihydropurine]-2,2',6'-trione 
1,3,7-trimethyl-5-hydroxyisouric acid 
1,3,7-trimethyl-8-(phenylmethyl)purine-2,6-dione 
1,3,7-trimethylisoguanine 
1,3,7-trimethyluric acid  
1,3-dibutyl-7-(2-oxopropyl)purine-2,6-dione 
1,3-dimethyl-7-(5-oxohexyl)purine-2,6-dione 
1,3-dimethyl-7-(phenylmethyl)-8-[2-(thiophen-2-ylmethylidene)hydrazinyl]purine-2,6-dione 
1,3-dimethyl-8-(3-methyl-1-piperidinyl)-7-[2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]ethyl]purine-2,6-dione 
1,3-dimethyl-8-[2-(1-pyrrolidinyl)ethylthio]-6-sulfanylidene-7H-purin-2-one 
1,3-dimethyl-8-[[methyl-(phenylmethyl)amino]methyl]-7-(2-methylpropyl)purine-2,6-dione 
1,3-dimethyl-8-[methyl-(phenylmethyl)amino]-7-[2-(2-pyrimidinylthio)ethyl]purine-2,6-dione 
1,3-dimethyluric acid 
1,7-dimethyluric acid  
1-methyl-3-propyl-7H-xanthine 
1-methyluric acid  
2',3'-secoguanosine 
2-(1,3-dimethyl-2,6-dioxo-7-purinyl)-N'-[2-(2-ethoxyphenoxy)-1-oxoethyl]acetohydrazide 
2-(1,3-dimethyl-2,6-dioxo-7-purinyl)-N-(phenylmethyl)-N-(2-pyridinyl)acetamide 
2-(1,3-dimethyl-2,6-dioxo-7-purinyl)-N-[3-[(4-methoxyphenyl)sulfamoyl]-4-methylphenyl]acetamide 
2-(1,3-dimethyl-2,6-dioxo-7-purinyl)acetic acid 
2-(4-hydroxyphenyl)ethanol +   
2-(\{8-[(3R)-3-aminopiperidin-1-yl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl\}methyl)benzonitrile 
2-[(1,3-dimethyl-2,6-dioxo-7-propyl-8-purinyl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide 
2-[(7-ethyl-1,3-dimethyl-2,6-dioxo-8-purinyl)thio]-N-(6-methyl-2-pyridinyl)acetamide 
2-[[3-methyl-7-(3-methylbutyl)-2,6-dioxo-8-purinyl]thio]propanoic acid methyl ester 
2-[[7-(3-chlorobut-2-enyl)-3-methyl-2,6-dioxo-8-purinyl]thio]butanoic acid ethyl ester 
2-furancarboxylic acid [4-[[[1,3-dimethyl-2,6-dioxo-7-(phenylmethyl)-8-purinyl]hydrazinylidene]methyl]phenyl] ester 
3'''-O-acetyldigitoxin 
3,5-dimethyl-4-isoxazolecarboxylic acid (3-butyl-2,6-dioxo-7-propyl-8-purinyl)methyl ester 
3,7-dimethyl-1-(phenylmethyl)-8-[(phenylmethyl)amino]purine-2,6-dione 
3,7-dimethylisoguanine 
3,7-dimethyluric acid 
3-butyl-8-(2-fluorophenyl)-7-(phenylmethyl)purine-2,6-dione 
3-isobutyl-1-methylxanthine +   
3-methyl-7-(2-phenylethyl)-8-(propylamino)purine-2,6-dione 
3-methyl-7-(phenylmethyl)-8-(propan-2-ylthio)purine-2,6-dione 
3-methyl-7-[(4-methylphenyl)methyl]-8-[2-(1-piperidinyl)ethylthio]purine-2,6-dione 
3-methyl-7-pentyl-8-(2-phenylethylthio)purine-2,6-dione 
4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)benzenesulfonic acid 
4-(methylamino)antipyrine 
4-[(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)methylamino]benzoic acid 
4-[2-[2-[3-methyl-2,6-dioxo-8-(1-piperidinyl)-7-purinyl]ethylidene]hydrazinyl]benzoic acid 
4-[7-(2-methoxyethyl)-2,6-dioxo-3-(phenylmethyl)-8-purinyl]benzonitrile 
4-[[7-[(4-fluorophenyl)methyl]-1,3-dimethyl-2,6-dioxo-8-purinyl]methyl]-1-piperazinecarboxylic acid ethyl ester 
4-aminoantipyrine 
5-hydroxyisouric acid +  
5-hydroxyisouric acid anion 
6-(9'-Purine-6',8'-diolyl)-2beta-suberosanone 
6-Thiourate  
7,8-dihydro-8-oxoguanine  
7-(2-chloroethyl)-1,3-dimethylpurine-2,6-dione 
7-(2-ethoxyethyl)-3-methyl-8-(1-pyrrolidinyl)purine-2,6-dione 
7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione 
7-(2-methoxyethyl)-3-methyl-8-(phenylthio)purine-2,6-dione 
7-(3-chlorobut-2-enyl)-1,3-dimethyl-8-(2-phenylethylamino)purine-2,6-dione 
7-(3-methoxypropyl)-3-(phenylmethyl)-8-(3-thiophenyl)purine-2,6-dione 
7-[(2-chloro-6-fluorophenyl)methyl]-1,3-dimethyl-8-(1-piperidinylmethyl)purine-2,6-dione 
7-[(2-chloro-6-fluorophenyl)methyl]-1,3-dimethyl-8-[(3-methyl-1-piperidinyl)methyl]purine-2,6-dione 
7-[(3-bromophenyl)methyl]-1,3-dimethyl-8-(2-methylpropylamino)purine-2,6-dione 
7-[(3-bromophenyl)methyl]-1,3-dimethyl-8-(3-pyridinylmethylamino)purine-2,6-dione 
7-[(4-fluorophenyl)methyl]-1,3-dimethyl-8-[(2-oxo-2-thiophen-2-ylethyl)thio]purine-2,6-dione 
7-[2-(1,3-benzothiazol-2-ylthio)ethyl]-1,3-dimethyl-8-(3-methyl-1-piperidinyl)purine-2,6-dione 
7-[2-hydroxy-3-(2-methylphenoxy)propyl]-3-methyl-8-(propan-2-ylthio)purine-2,6-dione 
7-[2-hydroxy-3-(4-methoxyphenoxy)propyl]-1,3-dimethyl-8-(1-piperidinyl)purine-2,6-dione 
7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethylpurine-2,6-dione 
7-\{2-hydroxy-3-[(naphthalen-1-yl)oxy]propyl\}-3-methyl-8-(morpholin-4-yl)-3,7-dihydropurine-2,6-dione 
7-benzyl-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydropurine-2,6-dione 
7-but-2-enyl-3-methyl-8-(3-phenylpropylthio)purine-2,6-dione 
7-but-2-enyl-3-methyl-8-(phenylmethylthio)purine-2,6-dione 
7-Methyluric acid 
7-methylxanthine 
8-(1,3-benzothiazol-2-ylthio)-3-methyl-7-pentylpurine-2,6-dione 
8-(2,5-dimethylphenoxy)-1,3-dimethyl-7-prop-2-enylpurine-2,6-dione 
8-(3-ethoxypropylamino)-1,3-dimethyl-7H-purine-2,6-dione 
8-(4-methoxyphenyl)-7-methyl-3-(phenylmethyl)purine-2,6-dione 
8-(butan-2-ylthio)-7-[(4-chlorophenyl)methyl]-3-methylpurine-2,6-dione 
8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione 
8-[(1-ethyl-3-piperidinyl)thio]-1,3-dimethyl-6-sulfanylidene-7H-purin-2-one 
8-[(2-fluoroanilino)hydrazinylidene]-1,3-dimethylpurine-2,6-dione 
8-[2-(2-bromo-3-phenylprop-2-enylidene)hydrazinyl]-7-(2-hydroxyethyl)-3-methylpurine-2,6-dione 
8-[[4-[2-furanyl(oxo)methyl]-1-piperazinyl]methyl]-1,3-dimethyl-7-[(2-methylphenyl)methyl]purine-2,6-dione 
8-[[4-[2-furanyl(oxo)methyl]-1-piperazinyl]methyl]-1,3-dimethyl-7-propylpurine-2,6-dione 
8-anilino-1,3-dimethyl-7H-purine-2,6-dione 
8-cyclopentyl-1,3-dimethyl-7H-purine-2,6-dione 
8-hydroxy-7-methylguanine 
8-oxoadenine 
8-oxoguanine 
8-phenyl-1,3-dipropyl-7H-purine-2,6-dione 
9-Methylxanthine 
[5-fluoro-1-(4-isopropylbenzylidene)-2-methylinden-3-yl]acetic acid 
acebutolol  
acebutolol hydrochloride 
aceclofenac  
acemetacin  
acetosyringone +  
acetylsalicylic acid +   
acetylstrophanthidin 
aclidinium +  
aclidinium bromide 
acyclovir  
adapalene  
adenosine +   
albuterol +   
alclofenac  
alminoprofen 
almotriptan +   
almotriptan malate 
alprenolol +   
amfenac +   
amfenac sodium hydrate 
aminophenazone  
amlexanox  
amodiaquine +   
amphetamine +   
ampiroxicam 
Anoro Ellipta 
antipyrine +   
apazone  
apigenin 7-O-beta-D-glucoside  
apigenin 7-O-beta-D-glucoside(1-) 
apocynin  
apremilast 
arasertaconazole +   
arformoterol +  
arformoterol fumarate +   
atenolol +   
atropine +   
azelastine +   
azelastine hydrochloride 
baicalin  
balsalazide +   
balsalazide disodium 
bambuterol +   
bambuterol hydrochloride +  
bamifylline 
beclomethasone +   
beclomethasone dipropionate 
bendazac 
benoxaprofen  
benzydamine  
bepridil +   
bevantolol +   
bevantolol hydrochloride +  
Bevespi Aerosphere 
biphenyl-4-ylacetic acid +  
bisoprolol +   
bitolterol +  
bitolterol mesylate +  
Breo Ellipta 
bretylium +   
bretylium tosylate  
bromfenac  
bromfenac sodium salt +  
bromfenac sodium salt sesquihydrate 
budesonide  
bufexamac 
bumadizone 
bumadizone calcium +  
bumadizone calcium hemihydrate 
cafaminol 
cafedrine 
carprofen +   
carteolol  
carteolol hydrochloride 
cilostazol  
cimicoxib 
cinalukast 
clenbuterol +   
clenbuterol hydrochloride +  
clidinium +   
clidinium bromide 
clofazimine  
clonixin 
clonixin lysine salt 
colterol 
corilagin  
cortisol +   
crisaborole 
cromoglycic acid 
cyclosporin A +   
deracoxib 
deslanoside 
devapamil 
dexibuprofen 
dexketoprofen 
diazoxide  
diclofenac +   
difenpiramide 
diflunisal  
digoxin +   
dimethazan 
diphemanil methylsulfate 
disodium cromoglycate  
disopyramide +   
dithiosalicylic acid 
dofetilide  
doxofylline 
DPCPX  
dronedarone  
droxicam 
dyphylline +  
eletriptan  
eletriptan hydrobromide 
encainide +  
encainide hydrochloride 
enprofylline +  
Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
entecavir (anhydrous) +  
esmolol +   
esmolol hydrochloride 
etamiphylline 
ethylisopropylamiloride  
etodolac +   
etofylline clofibrate 
etofylline nicotinate 
etoricoxib  
felodipine  
fenbufen  
fendosal 
fenetylline 
fenoprofen  
fenoprofen calcium 
fenoterol +   
fenoterol hydrobromide 
firocoxib 
flecainide  
flecainide acetate 
flufenamate 
flufenamic acid  
flunisolide  
flunixin  
flunixin meglumine  
flunoxaprofen 
flurbiprofen +   
fluticasone +   
fluticasone furoate +  
fluticasone propionate 
formoterol 
formoterol fumarate +   
ganciclovir +   
garenoxacin 
glafenine  
glyburide  
guanine +   
hypoxanthine +   
hypoxanthine 3-N-oxide +  
ibufenac  
ibuprofen +   
ibuproxam 
indacaterol 
indacaterol maleate +  
indometacin +   
indoprofen  
ipratropium bromide +  
ipratropium bromide hydrate 
isoguanine 
isoprenaline  
isoxicam 
istradefylline  
kebuzone 
ketoprofen  
ketorolac  
ketotifen  
ketotifen fumarate 
khellin 
leflunomide  
levosimendan 
lidocaine +   
lidocaine hydrochloride +  
lidocaine hydrochloride monohydrate 
lonazolac 
lonazolac calcium 
lornoxicam  
losartan +   
loxoprofen +   
loxoprofen sodium +  
loxoprofen sodium hydrate 
LSM-1748 
lumiracoxib  
magnesium sulfate +   
mavacoxib 
meclofenamic acid  
mefenamic acid  
meloxicam  
mesalamine  
metamizole 
metamizole sodium  
methoxyphenamine +  
methylguanine +   
methylhypoxanthine +  
metiazinic acid 
metipranolol  
metipranolol hydrochloride 
mexiletine +   
mexiletine hydrochloride 
Migrenin (TN) 
miroprofen 
mofebutazone 
montelukast +   
moricizine +   
moricizine hydrochloride 
N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide 
N-acetylprocainamide 
nabumetone  
nadolol  
naproxcinod 
naproxen +   
naproxen sodium 
naproxol 
nedocromil  
nepafenac 
nimesulide  
nitric oxide  
nitroflurbiprofen  
nitroproston 
nitrosulindac 
norverapamil  
O-methylsalicylic acid +   
O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE 
oleocanthal 
olodaterol  
olodaterol hydrochloride +  
olsalazine 
olsalazine sodium 
orciprenaline  
ouabain  
oxametacin 
oxaprozin  
oxyphenbutazone +   
oxyphenbutazone hydrate 
paracetamol +   
parecoxib  
parthenolide +   
pentifylline 
Pentoxifylline  
phentetramine 
phenylbutazone +   
piclamilast  
pilsicainide 
pimefylline 
pirfenidone  
piroxicam +   
practolol  
procainamide +   
procainamide hydrochloride 
proglumetacin +  
proglumetacin dimaleate 
propafenone  
propafenone hydrochloride 
Propentofylline 
propranolol +   
propyphenazone 
protheobromine 
Proxyphylline 
pseudoephedrine 
quinidine +   
ranolazine  
reproterol 
ritropirronium bromide +  
robenacoxib 
rofecoxib  
roflumilast  
rosmarinic acid +   
S-nitrosoglutathione  
salicin +   
salmeterol 
salsalate  
SC560 
scullcapflavone II 
sertaconazole  
sertaconazole nitrate 
sodium meclofenamate monohydrate 
sotalol  
sotalol hydrochloride 
Stiolto Respimat 
sulfasalazine  
sulindac +   
sulindac sulfide  
suprofen  
suxibuzone  
tenidap  
tenoxicam  
tepoxalin  
terbutaline +   
teriflunomide  
Theacrine 
theobromine  
theodrenaline 
theophylline  
Theophylline sodium acetate 
tiaprofenic acid  
tiotropium 
tiotropium bromide  
tiotropium bromide hydrate +  
tocainide 
tolfenamic acid  
tolmetin  
tolmetin sodium +  
tolmetin sodium dihydrate 
tomelukast  
tranilast  
trans-piceid  
urate(2-) +  
uric acid +   
Utibron Neohaler 
valdecoxib +   
vedaprofen 
verapamil  
vilanterol +  
vilanterol trifenate +  
willow bark extract 
xanthine +   
ximoprofen 
zardaverine  
zileuton  
zomepirac  

Synonyms
Related Synonyms: 3,7-dihydro-3-propyl-1H-purine-2,6-dione ;   3-Propyl-3,7-dihydro-purine-2,6-dione ;   3-n-propylxanthine ;   3-propylxanthine ;   Formula=C8H10N4O2 ;   InChI=1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14) ;   InChIKey=SIQPXVQCUCHWDI-UHFFFAOYSA-N ;   SMILES=CCCn1c2nc[nH]c2c(=O)[nH]c1=O ;   enprofilina ;   enprofyllinum
Alternate IDs: CHEBI:665397
Xrefs: Beilstein:4189165 "Beilstein" ;   CAS:41078-02-8 "ChemIDplus" ;   CAS:41078-02-8 "KEGG DRUG" ;   DrugBank:DB00824 ;   Drug_Central:1015 "DrugCentral" ;   KEGG:D04006

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.