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Term:
3-hydroxy-2,2-dimethylbutyric acid (CHEBI:131392)
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Parent Terms Term With Siblings Child Terms
(1-hydroxycyclohexyl)acetic acid +  
(11R,12S)-EET 
(13R)-13-dihydrocarminomycin 
(1R,2S)-nortilidine +  
(1S,2R)-nortilidine +  
(20S,23)-dihydroxyvitamin D3 
(20S,23,24)-trihydroxyvitamin D3 
(20S,23,25)-trihydroxyvitamin D3 
(2E,5E)-tetradecadienoyl-CoA 
(2E,6E)-farnesyl monophosphate 
(2S)-2-(4-\{[(1R,2S)-2-hydroxycyclopentyl]methyl\}phenyl)propanoic acid 
(2S,3R)-3-hydroxy-2-methylpentanoic acid 
(3R)-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylic acid 
(3S,4S)-3-hydroxy-4-methyldecanoic acid +  
(4E,7E,10E,13E,16E)-docosapentaenoylcarnitine 
(4E,7E,10E,13E,16E,19E)-docosahexaenoylcarnitine 
(5-hydroxyindol-3-yl)acetic acid  
(5E)-tetradecenoyl-CoA 
(5E)-tetradecenoyl-L-carnitine 
(5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoic acid 
(6-methoxy-2-naphthyl)acetic acid 
(8R,9S)-EET 
(8S,9R)-EET 
(R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid 
(S)-3-hydroxy-2-oxo-3-phenylpropanoic acid 
(S)-3-hydroxydecanoic acid +  
(S)-3-hydroxytetradecanoic acid +  
(S)-glaucine +   
(Z)-icos-13-enoic acid 
1',4-dihydroxymidazolam 
1,1,1,3,3,3-hexafluoropropan-2-ol  
1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid 
1,2-bis(octadec-9-enoyl)phosphatidic acid +   
1,2-ditetradecanoyl-3-(6-sulfoquinovopyranosyl)glycerol 
1-(2,3-dihydro-1H-pyrrolizin-5-yl)-2-propen-1-one 
1-(3-chlorophenyl)piperazine  
1-docosanoyl-2-pentadecanoyl-sn-glycero-3-phosphoethanolamine 
1-docosanoyl-2-tetradecanoyl-sn-glycero-3-phosphoethanolamine 
1-hexadecanoyl-2-icosanoyl-sn-glycero-3-phosphoethanolamine 
1-hydroxymidazolam +   
1-hydroxymidazolam beta-D-glucuronide  
1-icosanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine 
1-icosanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine 
1-methylhypoxanthine 
1-O-(5,6-epoxyretinoyl)-beta-D-glucuronic acid 
1-octadecanoyl-2-pentadecanoyl-sn-glycero-3-phosphocholine 
1-pentadecanoyl-2-docosanoyl-sn-glycero-3-phosphoethanolamine 
1-pentadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine 
1-pentadecanoyl-sn-glycero-3-phosphocholine 
1-tetradecanoyl-2-docosanoyl-sn-glycero-3-phosphoethanolamine 
10,11-trans-dihydroxy-10,11-dihydrocarbamazepine +  
10-HETE 
11 hydroxy-(14R,15S)-epoxy-(5Z,8Z,12E)-icosatrienoic acid 
11-HEPE +  
12(S)-HEPE 
12-hydroxynevirapine 
13,14-dihydroprostaglandin F2alpha 
13-HETE +  
16-hydroxytriptolide 
19-hydroxyleukotriene B4 
2,3-epoxymenatetrenone 
2,4-dihydroxyacetophenone-5-O-sulfate 
2,6-dimethylaniline +   
2-(acetoxyamino)-3-methylimidazo[4,5-f]quinoline 
2-(hydroxymethyl)-4-oxobutanoic acid 
2-ethyl-3-hydroxybutyric acid 
2-exo-hydroxy-1,4-cineole 
2-formylbenzoic acid 
2-hydroxyibuprofen 
2-methoxyacetaminophen glucuronide 
2-methoxyacetaminophen glucuronide(1-) 
2-methoxyacetaminophen sulfate 
2-methoxyacetaminophen sulfate(1-) 
2-methylpropane-1,2-diol 
23-acetoxysoladulcidine 
2beta-hydroxytestosterone 
3'-hydroxy-4'-methoxydiclofenac 
3'-hydroxydiclofenac 
3,4-dihydro-4-[(5-methyl-2-furanyl)methylene]-2H-pyrrole 
3,4-dihydroxymandelic acid  
3,5-dihydroxyphenylacetic acid 
3-(5-methylfurfuryl)pyrrole 
3-chlorobenzoic acid 
3-hydroxy fatty acid +  
3-hydroxy-2,2-dimethylbutyric acid 
A 3-hydroxy monocarboxylic acid that is 2,2-dimethylbutyric acid carrying a single hydroxy substituent at position 3.
3-hydroxy-2-methylbutanoic acid +  
3-hydroxy-3-methyl-2-oxopentanoic acid +  
3-hydroxy-3-methylhexanoic acid +  
3-hydroxy-5-oxohexanoic acid +  
3-hydroxybut-2-enoic acid +   
3-hydroxybutyric acid +   
3-hydroxydocosanoic acid +  
3-hydroxyhexacosanoic acid +  
3-hydroxyhexanoic acid +  
3-hydroxyisobutyric acid +  
3-hydroxyisovaleric acid +   
3-hydroxymethylantipyrine 
3-hydroxyoctadecanoic acid +  
3-hydroxyoctanoic acid +  
3-hydroxypropionic acid +   
3-hydroxypyruvic acid  
3-hydroxytetradecanoic acid +  
4',5-dihydroxydiclofenac 
4'-hydroxydiclofenac  
4-(acetylamino)-3-hydroxyphenyl hydrogen sulfate 
4-(acetylamino)-3-hydroxyphenyl sulfate 
4-(methylamino)antipyrine 
4-(trifluoromethyl)phenol 
4-acetamidoantipyrine 
4-aminoantipyrine 
4-bromophenol 
4-ethoxyaniline +   
4-formylaminoantipyrine 
4-heptanone 
4-hydroxy-2,6-dimethylaniline 
4-hydroxy-6-methylaniline 
4-hydroxymidazolam +   
4-hydroxymidazolam beta-D-glucuronide 
4-hydroxypropofol 
4-methoxy-17beta-estradiol +   
5'-hydroxyomeprazole  
5(S),15(S)-DiHETE 
5(S),15(S)-DiHETE(1-) 
5,6-epoxyretinoic acid +  
5,7-icosanedione 
5-carboxy-2'-deoxyuridine 
5-fluorouridine 5'-monophosphate 
5-hydroxybenzimidazole 
5-hydroxydiclofenac  
5-hydroxydiclofenac quinone imine 
5-methoxyindole-3-acetic acid  
5-methyldihydrofolic acid 
5-O-desmethyldonepezil 
6,8-icosanedione 
6-azauridine +   
7-HETE 
7-hydroxyticlopidine 
7alpha-hydroxydehydroepiandrosterone 
7alpha-hydroxypregnenolone 
8-epi-prostaglandin E2  
acetaminophen O-beta-D-glucosiduronic acid  
acetohydrazide +   
ACT-132577 +   
ACT-333679 +  
adefovir +   
agrochelin 
all-trans-retinyl dodecanoate 
allocholic acid +  
allodeoxycholic acid +  
alloxanthine +   
alpha-D-galactosyl-(1->4)-beta-D-galactosyl-N-(pentacosanoyl)sphingosine 
alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer 
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)-[alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->3)]-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer +  
aripiprazole  
artemoin A 
artemoin B 
artemoin C 
artemoin D 
Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2 
asparagoside F 
atenolol acid 
atenolol-desisopropyl 
azure B  
benzoylhypaconine  
beta-(methylenecyclopropyl)pyruvic acid 
beta-D-galactosyl-(1->4)-beta-D-galactosyl-N-(pentacosanoyl)sphingosine 
beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer 
carbamazepine-10,11-epoxide  
carboxyibuprofen 
carboxyibuprofen(2-) 
ceftaroline +  
clopidogrel carboxylic acid 
CNDAC +  
cohibin C 
cohibin D 
columbianadin 
cotinine N-oxide 
crosatoside B 
cyclodopa 5-beta-D-glucoside 
cyclosporin A metabolite M1 +  
cyclosporin A metabolite M10 
cyclosporin A metabolite M13 
cyclosporin A metabolite M16 +  
cyclosporin A metabolite M17 +  
cyclosporin A metabolite M18 +  
cyclosporin A metabolite M1A 
cyclosporin A metabolite M1cAL 
cyclosporin A metabolite M21 +  
cyclosporin A metabolite M25 
cyclosporin A metabolite M26 
cyclosporin A metabolite M8 +  
cyclosporin A metabolite M9 
D617 
desmethyl loperamide 
desmethyldoxepin +  
desmethylnaproxen  
desmethylnaproxen sulfate 
desmethylnaproxen(1-) 
desmethylranitidine 
diclofenac beta-D-glucosiduronic acid 
didesethylflurazepam 
dioxoaminopyrine 
doxorubicinol 
egonol beta-D-glucoside 
erucamide  
ethisterone 
fenofibric acid 
ferulic acid 4-sulfate 
gamma-amino-beta-hydroxybutyric acid +  
glycinexylidide +  
guanidinoacetic acid 
hepoxilin A3 +  
HMBOA beta-D-glucoside 
hydroxyalbendazole 
hydroxyfenbendazole 
hyocholate 
hyocholic acid +  
hypothiocyanous acid 
imidaprilat  
indometacin +   
isolithocholic acid 
ixazomib +   
L-homoarginine 
L-lyxonic acid 
leucomethylene blue 
leukotriene B5  
leukotriene C3 
leukotriene D3 
lithocholic acid 3-O-(beta-D-glucuronide) 
lugdunin 
mevaldic acid 
mevinolinic acid 
monoethylglycinexylidide +   
monoisodecyl phthalate 
monopentyl phthalate 
mutalomycin 
N,N-didesmethylvenlafaxine 
N,O-didesmethylvenlafaxine 
N-(2,6-diethylphenyl)-2-chloroacetamide  
N-[(11Z)-octadecenoyl]sphinganine-1-phosphocholine 
N-[(15Z)-tetracosenoyl]sphingosine 1-phosphate 
N-acetyl-L-aspartate(2-) +  
N-acetyl-L-aspartic acid +   
N-acetylsulfamethoxazole 
N-carbamoylglycine +  
N-desmethylvenlafaxine 
N-ethyldiethanolamine 
N-hydroxy-MeIQx 
N-hydroxy-PhIP  
N-oleoylsphinganine-1-phosphocholine 
N-pentacosanoylsphingosine 
nitrazepam +   
nitrososulfadiazine 
nitrososulfapyridine 
nociceptin  
nodakenetin +  
norfentanyl 
nortriptyline  
norverapamil  
O-desethyl candesartan 
O-desmethylvenlafaxine 
O-heptadecanoylcarnitine 
O-pentadecanoylcarnitine 
oleyl acetate 
oxidopamine  
oxyphenbutazone +   
p-tolyl beta-D-glucuronide 
p-tolyl beta-D-glucuronide(1-) 
paliperidone 
paracetamol sulfate +   
pelargonidin 3-O-sophoroside 
peramivir 
perindoprilat 
phosphatidylethanolamine 36:2 +  
phosphatidylethanolamine 37:2 
phosphatidylethanolamine 38:3 +  
phosphatidylethanolamine 38:4 +  
pivaloyl-CoA 
prednisolone +   
procainamide 4-hydroxylamine 
proglumide +  
promazine sulfoxide 
propyl propionate 
prostaglandin B3 
psilocin +  
pyrazine-2-carboxylic acid  
pyridine N-oxide +   
rac-nortilidine 
ramiprilat  
ranitidine N-oxide 
ranitidine-S-oxide 
resolvin D2  
resolvin E2 
riddelliine N-oxide 
ritalinic acid  
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteinate 
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteine 
S-propyl propanethiosulfinate 
SN-38 +   
somatostatin-28 
spiraprilat +   
sulfadiazine hydroxylamine 
sulfapyridine hydroxylamine 
tauro-beta-muricholate 
tauro-beta-muricholic acid  
tauroursocholate 
tauroursocholic acid 
tedizolid 
tenofovir (anhydrous) +   
teriflunomide  
theophylline +   
trandolaprilat 
tridodecylamine 
tropic acid +   
Tyr-Met 
uridine +   
WR-1065  
zofenoprilat 

Synonyms
Exact Synonyms: 3-hydroxy-2,2-dimethylbutanoic acid
Related Synonyms: 2,2-Dimethyl-3-hydroxybutanoic acid ;   2,2-Dimethyl-3-hydroxybutyric acid ;   DMHB ;   Formula=C6H12O3 ;   InChI=1S/C6H12O3/c1-4(7)6(2,3)5(8)9/h4,7H,1-3H3,(H,8,9) ;   InChIKey=RVWQQCKPTVZHJM-UHFFFAOYSA-N ;   SMILES=C(=O)(O)C(C(C)O)(C)C
Xrefs: CAS:29269-83-8 "ChemIDplus" ;   Chemspider:134834 ;   PMID:1814736 "Europe PMC" ;   Reaxys:1752724 "Reaxys"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.