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(+)-(11R,2'S)-erythro-mefloquine +   
(+)-artemisinin +   
(-)-(11S,2'R)-erythro-mefloquine +   
(-)-anisomycin  
(R)-7-butyl-6,8-dihydroxy-3-[(3E)-pent-3-en-1-yl]-3,4-dihydroisochromen-1-one 
(R)-iclaprim +  
(R)-temafloxacin +  
(S)-iclaprim +  
(S)-temafloxacin +  
1,1-dihydroxy-3-ethoxy-2-butanone 
1,2,3-triazines 
1,2,4-triazines +   
1,3,5-triazines +   
1-(2-CHLOROPHENYLSULFONYL)-3-(4-METHOXY-6-METHYL-L,3,5-TRIAZIN-2-YL)UREA 
2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone 
2,4-diamino-6,7-diisopropylpteridine 
2-phenoxyethanol +  
21beta-hydroxyolean-12-en-3-one 
3,15-di-O-acetylbruceolide 
3-(Z)-caffeoyllupeol 
3-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]triazin-4-one 
4-((4,6-bis(octylthio)-1,3,5-triazin-2-yl)amino)-2,6-di-tert-butylphenol 
4-amino-1-[4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-1,3,5-triazin-2-one 
4-aminofolic acid 
4-terpineol +   
5,7,3'-trihydroxy-4',5'-(2'''',2''''-dimethylpyran)-8,2'-di(3-methyl-2-butenyl)-(2S)-flavanone 
5-chloro-7-iodoquinolin-8-ol  
5-O-methylcelebixanthone 
5-oxo-3-sulfanylidene-2H-1,2,4-triazine-6-carboxylic acid ethyl ester 
7-deacetylgedunin 
8-azahypoxanthine 
9-aminoacridine  
9-aminoacridine hydrochloride 
[4-methoxy-6-(1-piperidinyl)-1H-1,3,5-triazin-2-ylidene]-nitrosomethanamine 
acaricide drug +   
acedapsone 
amburoside A 
aminocandin 
amodiaquine +   
amphotericin B +   
amphotericin B methyl ester  
anilazine 
annomontine  
anthelminthic drug +   
antifungal drug +   
antileishmanial agent +   
antimicrobial drug +   
antiparasitic agent +   
antiplasmodial drug +   
antiprotozoal drug +   
antiseptic drug +   
antitrichomonal drug +   
artemether  
artesunate  
atovaquone  
aureothin 
bauhinoxepin F 
bauhinoxepin I 
bauhinoxepin J 
benznidazole 
benzoylmesaconine  
betulinic acid +   
bicozamycin 
bidebiline C 
bidebiline D 
bielschowskysin 
bipinnatone A 
bipinnatone B 
borrelidin  
bortezomib  
brodimoprim 
bromophycolide A 
bruceolide +  
caesalpinin C 
caesalpinin D 
caesalpinin F 
callophycoic acid A 
callophycoic acid B 
callophycoic acid C 
callophycoic acid D 
callophycoic acid E 
callophycoic acid F 
callophycoic acid G 
callophycoic acid H 
callophycol A 
callophycol B 
caribenol A 
caribenol B 
caseargrewiin A 
caseargrewiin B 
caseargrewiin C 
caseargrewiin D 
caspofungin +   
caspofungin acetate 
cassiarin A 
cassiarin B 
celebixanthone +  
cerulenin  
chaetoxanthone A 
chaetoxanthone B 
chaetoxanthone C 
chlorhexidine +   
chloroquine +   
chlorquinaldol 
chlortetracycline  
cilofungin 
cinoxacin  
ciprofloxacin +   
ciprofloxacin dihydrochloride 
ciprofloxacin hydrochloride (anhydrous) +  
ciprofloxacin hydrochloride hydrate 
clomocycline 
clotrimazole  
coccidiostat +   
cochinchinone C 
conessine 
cordyheptapeptide A 
cordyol C 
costunolide +   
crambescidin 800 
cryptolepine  
cycloguanil +  
A triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil.
D-cycloserine +   
dapsone +   
diallyl trisulfide  
diaveridine 
dihydroartemisinin  
dimetridazole 
diminazene  
diminazene diaceturate  
diminazene(2+) +   
dioncopeltine A 
dioncophylline A 
dioncophylline C 
diuvaretin 
docetaxel anhydrous +  
doxycycline +   
dragomabin 
dragonamide A 
dzununcanone 
E64 
EC 1.5.1.3 (dihydrofolate reductase) inhibitor +   
Echinacea extract 
echinocandin B 
ectoparasiticide +   
ELQ-271 
emetine +   
eprinomectin  
Eunicea sesquiterpenoid 2 
Eunicea sesquiterpenoid 3 
eurycomanone  
exiguaflavanone A 
exiguaflavanone B 
fenticlor 
fumagillin +   
furagin 
furazolidone  
ganciclovir +   
gatifloxacin +   
gedunin +   
geneticin  
GNF5343 
gutolactone 
hirsutellide A 
hydroxychloroquine  
iclaprim 
ikarugamycin 
imidocarb 
isariotin F 
Isomethiozin 
isonordoperoxide 
ivermectin  
lactucin +  
lactucopicrin 
leachianone A 
leflunomide  
lonchocarpenin 
longirostrerone A 
longirostrerone B 
longirostrerone C 
Lonsurf 
lumefantrine 
lycorine  
lymecycline 
manzamine A +  
mecillinam +  
mefloquine  
Melarsoprol  
Menazon 
methotrexate  
methotrexate disodium 
methylene blue  
metronidazole +   
metronidazole benzoate 
metronidazole hydrochloride 
micafungin 
miltefosine  
minquartynoic acid 
mollicellin B 
mollicellin C 
mollicellin E 
mollicellin J 
mollicellin K 
mollicellin L 
mollicellin M 
N-(2-furanylmethyl)-2-(4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]triazin-3-yl)acetamide 
N-acetyl-L-cysteinate 
N-acetyl-L-cysteine +   
nardoperoxide 
neurolenin A 
neurolenin B 
neurolenin C 
neurolenin D 
nifurtoinol 
nitarsone 
nitrofurantoin  
nitroxoline  
norcaesalpinin D 
norcaesalpinin E 
norlichexanthone 
nostocarboline 
O-(chloroacetylcarbamoyl)fumagillol  
ofloxacin +   
ornidazole  
oxiconazole  
oxiconazole nitrate 
oxolinic acid 
paromomycin +   
paromomycin sulfate 
pefloxacin +  
pemetrexed  
pemetrexed disodium +  
pemetrexed disodium heptahydrate 
phomoxanthone A 
phomoxanthone B 
physalin B 
physalin D 
physalin F 
physalin G 
piperaquine 
pivmecillinam +  
pracinostat 
pralatrexate 
primaquine  
proguanil  
Prosulfuron 
pseudobaptigenin +  
pseudobaptigenin(1-) 
puromycin +   
pyrimethamine  
quercetin-7-O-[alpha-L-rhamnopyranosyl(1->6)-beta-D-galactopyranoside] 
quinacrine +   
quinidine +   
quinine +   
quinine sulfate +  
quinine(1+) +   
ribavirin  
robustaside D 
robustaside E 
robustaside F 
robustaside G 
rolitetracycline 
ronidazole 
rosoxacin 
salicylic acid +   
samaderine B 
samaderine E 
samaderine X 
samaderine Z 
scutianthraquinone A 
scutianthraquinone B 
scutianthraquinone C 
simalikalactone D 
solasodine  
solasodine(1+) +  
sophoraflavanone G 
sulfacetamide 
sulfacetamide sodium 
sulfacetamide sodium anhydrous +  
sulfadiazine  
sulfadimethoxine  
sulfadoxine 
sulfaguanidine 
sulfamerazine  
sulfamethazine +   
sulfamethizole 
sulfamethoxazole +   
sulfamethoxydiazine 
sulfamethoxypyridazine 
sulfapyridine  
sulfasalazine  
sulfathiazole +  
sulfisomidine  
tafenoquine 
tazobactam  
tazobactam sodium +  
temafloxacin 
tetracycline +   
tetracycline zwitterion 
tinidazole  
tioconazole 
tosufloxacin 
tosufloxacin tosylate +  
tosufloxacin tosylate hydrate 
triacsin C  
triazine +  
triclosan  
trimethoprim +   
trypanocidal drug +   
venturamide A 
venturamide B 
WLL-vs 
Zerbaxa 

Synonyms
Exact Synonyms: 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine
Related Synonyms: 1-(p-chlorophenyl)-4,6-diamino-2,2-dimethyl-1,2-dihydro-s-triazine ;   Chlorcycloguanil ;   Formula=C11H14ClN5 ;   InChI=1S/C11H14ClN5/c1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8/h3-6H,1-2H3,(H4,13,14,15,16) ;   InChIKey=QMNFFXRFOJIOKZ-UHFFFAOYSA-N ;   SMILES=C1(N(C(N)=NC(=N1)N)C2=CC=C(C=C2)Cl)(C)C
Xrefs: Beilstein:229760 "ChemIDplus" ;   CAS:516-21-2 "ChemIDplus" ;   CAS:516-21-2 "DrugCentral" ;   Drug_Central:754 "DrugCentral" ;   HMDB:HMDB0060974 ;   PDBeChem:1CY ;   PMID:15228254 "Europe PMC" ;   PMID:29061131 "Europe PMC" ;   PMID:29882324 "Europe PMC" ;   PMID:6385887 "Europe PMC" ;   PMID:8494394 "Europe PMC" ;   PMID:9713549 "Europe PMC" ;   Reaxys:229760 "Reaxys"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.