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Term:
17alpha-hydroxy-C21-steroid (CHEBI:138141)
Annotations: Rat: (158) Mouse: (157) Human: (161) Chinchilla: (0) Bonobo: (0) Dog: (3) Squirrel: (0) Pig: (2)
Parent Terms Term With Siblings Child Terms
C21-steroid +     
(20R)-17alpha,20-dihydroxycholesterol 
11,21-dioxoprogesterone 
11beta,17alpha,21-trihydroxypregnenolone 
16alpha,17alpha-dihydroxypregnenolone 
17,20-dihydroxypregn-4-en-3-one +   
17-epiestriol +  
17-hydroxypregnenolone 3-sulfate 
17-hydroxyprogesterone 3-O-(carboxymethyl)oxime 
17alpha,21-dihydroxypregnenolone 
17alpha-estradiol +  
17alpha-hydroxy-C21-steroid +   
Any C21-steroid carrying a hydroxy substituent at the 17alpha-position. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure.
17alpha-hydroxypregn-5-ene-3,20-dione 
17alpha-hydroxypregnenolone +   
17alpha-hydroxyprogesterone  
17alpha-hydroxywithanolide D 
20-hydroxy-3-oxopregn-4-en-21-al 
20-hydroxypregn-4-en-3-one +   
21-acetoxy-11beta,17-dihydroxy-6alpha-methylpregn-4-ene-3,20-dione 
21-dehydrocortisol  
21-dehydrocortisone 
21-hydroxy-C21-steroid 
3-hydroxypregnan-20-one +   
3beta-hydroxy-16alpha,17alpha-epoxypregnenolone +  
4,5-dihydrocortisone +   
4-pregnen-3beta,20alpha-diol 
4-pregnen-3beta-ol-20-one 
5alpha-androstane-3beta,17alpha-diol +  
5alpha-pregnane +   
5beta-dihydroepitestosterone 
5beta-pregn-11-ene-3,20-dione 
5beta-pregnane +   
5beta-pregnane-3,20-dione 
6-methylprednisolone +   
6alpha-fluoro-17-hydroxycorticosterone 21-acetate 
6beta,16alpha,17alpha-trihydroxyprogesterone 
6beta-hydroxycortisol  
6beta-hydroxycortisone 
7alpha-hydroxypregnenolone 
9,11alpha-epoxypregn-4-ene-3,20-dione 
9-fluoro-11beta,17,21-trihydroxy-2alpha-methylpregn-4-ene-3,20-dione 21-acetate 
alclometasone 
algestone +  
beclomethasone +   
betamethasone +   
betamethasone acetate 
betamethasone phosphate 
C21-steroid hormone +   
clobetasol +   
convallasaponin A 
cortancyl 
corticosterone +   
cortisol 21-sulfate 
cortisol phosphate 
cortisone +   
cyproterone +   
dexamethasone +   
dexonorgestrel 
diflorasone +   
epitestosterone +   
floribundasaponin A 
fludrocortisone +   
fludrocortisone acetate 
flumethasone +   
flumethasone pivalate 
fluorometholone +   
fluticasone +   
hydrocortamate +  
hydrocortisone caproate 
hydroxypregnenolone +   
loteprednol +   
mannioside A 
medroxyprogesterone +   
megestrol +   
methyl prednisolone-16-carboxylate +  
methylprednisolone acetate 
mometasone +   
pennogenin +  
prednisolone +   
prednisolone phosphate 
prednisolone-16-carboxylic acid +  
prednisone +   
pregn-4-en-3-one 
pregn-5-ene-3,20-dione 
pregna-4,9(11)-diene-3,20-dione 
pregnan-21-al 
pregnan-21-ol 
pregnenolone +   
tetrahydrocortisol 
tixocortol +  
triamcinolone +   
tubocapsanolide F 

Synonyms
Related Synonyms: Formula=C21H36O ;   InChI=1S/C21H36O/c1-4-21(22)14-11-18-16-9-8-15-7-5-6-12-19(15,2)17(16)10-13-20(18,21)3/h15-18,22H,4-14H2,1-3H3/t15?,16?,17?,18?,19?,20?,21-/m1/s1 ;   InChIKey=JSIVWCLRCGAVHN-ILZKQPLKSA-N ;   SMILES=C1CCCC2C1(C3C(CC2)C4C(CC3)([C@](CC4)(CC)O)C)C ;   a 17alpha-hydroxy-C21-steroid
Xrefs: MetaCyc:17a-hydroxy-C21-steroids "SUBMITTER"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.