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Term:
cyclosporin A metabolite M21 (CHEBI:140171)
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Parent Terms Term With Siblings Child Terms
(13R)-13-dihydrocarminomycin 
(1R,2S)-nortilidine +  
(1S,2R)-nortilidine +  
(2S)-2-(4-\{[(1R,2S)-2-hydroxycyclopentyl]methyl\}phenyl)propanoic acid 
(5-hydroxyindol-3-yl)acetic acid  
(6-methoxy-2-naphthyl)acetic acid 
1',4-dihydroxymidazolam 
1,1,1,3,3,3-hexafluoropropan-2-ol  
1-(3-chlorophenyl)piperazine  
1-hydroxymidazolam +   
1-hydroxymidazolam beta-D-glucuronide  
10,11-trans-dihydroxy-10,11-dihydrocarbamazepine +  
12-hydroxynevirapine 
2,6-dimethylaniline +   
2-formylbenzoic acid 
2-hydroxyibuprofen 
2-methoxyacetaminophen glucuronide 
2-methoxyacetaminophen glucuronide(1-) 
2-methoxyacetaminophen sulfate 
2-methoxyacetaminophen sulfate(1-) 
3'-hydroxy-4'-methoxydiclofenac 
3'-hydroxydiclofenac 
3,4-dihydroxymandelic acid  
3,5-dihydroxyphenylacetic acid 
3-chlorobenzoic acid 
3-hydroxy-2,2-dimethylbutyric acid 
3-hydroxymethylantipyrine 
4',5-dihydroxydiclofenac 
4'-hydroxydiclofenac  
4-(acetylamino)-3-hydroxyphenyl hydrogen sulfate 
4-(acetylamino)-3-hydroxyphenyl sulfate 
4-(methylamino)antipyrine 
4-(trifluoromethyl)phenol 
4-acetamidoantipyrine 
4-aminoantipyrine 
4-ethoxyaniline +   
4-formylaminoantipyrine 
4-hydroxy-2,6-dimethylaniline 
4-hydroxy-6-methylaniline 
4-hydroxymidazolam +   
4-hydroxymidazolam beta-D-glucuronide 
4-hydroxypropofol 
5'-hydroxyomeprazole  
5-carboxy-2'-deoxyuridine 
5-fluorouridine 5'-monophosphate 
5-hydroxydiclofenac  
5-hydroxydiclofenac quinone imine 
5-O-desmethyldonepezil 
6-azauridine +   
7-hydroxyticlopidine 
acetaminophen O-beta-D-glucosiduronic acid  
acetohydrazide +   
ACT-132577 +   
ACT-333679 +  
adefovir +   
alloxanthine +   
aripiprazole  
atenolol acid 
atenolol-desisopropyl 
azure B  
carbamazepine-10,11-epoxide  
carboxyibuprofen 
carboxyibuprofen(2-) 
ceftaroline +  
clopidogrel carboxylic acid 
CNDAC +  
cotinine N-oxide 
cyclosporin A metabolite M1 +  
cyclosporin A metabolite M10 
cyclosporin A metabolite M13 
cyclosporin A metabolite M16 +  
cyclosporin A metabolite M17 +  
cyclosporin A metabolite M18 +  
cyclosporin A metabolite M1A 
cyclosporin A metabolite M1cAL 
cyclosporin A metabolite M21 +  
A cyclosporin A derivative that is cyclosporin A in which residue 4 (N-methylleucine) has undergone N-demethylation.
cyclosporin A metabolite M25 
cyclosporin A metabolite M26 
cyclosporin A metabolite M8 +  
cyclosporin A metabolite M9 
D617 
desmethyl loperamide 
desmethyldoxepin +  
desmethylnaproxen  
desmethylnaproxen sulfate 
desmethylnaproxen(1-) 
desmethylranitidine 
diclofenac beta-D-glucosiduronic acid 
didesethylflurazepam 
dioxoaminopyrine 
doxorubicinol 
ethisterone 
fenofibric acid 
glycinexylidide +  
hydroxyalbendazole 
hydroxyfenbendazole 
imidaprilat  
indometacin +   
ixazomib +   
mevinolinic acid 
monoethylglycinexylidide +   
N,N-didesmethylvenlafaxine 
N,O-didesmethylvenlafaxine 
N-acetylsulfamethoxazole 
N-desmethylvenlafaxine 
nitrazepam +   
nitrososulfadiazine 
nitrososulfapyridine 
norfentanyl 
nortriptyline  
norverapamil  
O-desethyl candesartan 
O-desmethylvenlafaxine 
oxidopamine  
oxyphenbutazone +   
paliperidone 
paracetamol sulfate +   
perindoprilat 
prednisolone +   
procainamide 4-hydroxylamine 
proglumide +  
promazine sulfoxide 
psilocin +  
pyrazine-2-carboxylic acid  
pyridine N-oxide +   
rac-nortilidine 
ramiprilat  
ranitidine N-oxide 
ranitidine-S-oxide 
ritalinic acid  
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteinate 
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteine 
SN-38 +   
spiraprilat +   
sulfadiazine hydroxylamine 
sulfapyridine hydroxylamine 
tedizolid 
tenofovir (anhydrous) +   
teriflunomide  
theophylline  
trandolaprilat 
uridine +   
WR-1065  
zofenoprilat 

Synonyms
Exact Synonyms: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Related Synonyms: 9-L-leucinecyclosporin A ;   Csa M21 ;   Formula=C61H109N11O12 ;   InChI=1S/C61H109N11O12/c1-24-26-27-39(15)51(74)50-55(78)65-42(25-2)57(80)67(18)32-47(73)64-43(28-33(3)4)53(76)66-48(37(11)12)60(83)68(19)44(29-34(5)6)54(77)62-40(16)52(75)63-41(17)56(79)69(20)45(30-35(7)8)58(81)70(21)46(31-36(9)10)59(82)71(22)49(38(13)14)61(84)72(50)23/h24,26,33-46,48-51,74H,25,27-32H2,1-23H3,(H,62,77)(H,63,75)(H,64,73)(H,65,78)(H,66,76)/b26-24+/t39-,40+,41-,42+,43+,44+,45+,46+,48+,49+,50+,51-/m1/s1 ;   InChIKey=MIIRLHRXLLVIMF-WKHWYDSQSA-N ;   SMILES=[C@H]1(N(C([C@@H](N(C([C@@H](N(C)C([C@@H](N(C([C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@@H](NC(CN(C([C@@H](NC1=O)CC)=O)C)=O)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)C)=O)C)=O)C)CC(C)C)=O)CC(C)C)=O)C)C(C)C)=O)C)[C@@H]([C@@H](C/C=C/C)C)O ;   cyclosporin A metabolite AM4N ;   cyclosporin metabolite AM4N ;   cyclosporin metabolite M21 ;   cyclosporine A metabolite AM4N ;   cyclosporine A metabolite M21 ;   cyclosporine metabolite AM4N ;   cyclosporine metabolite M21
Xrefs: CAS:89270-23-5 "ChemIDplus" ;   PMID:2642763 "Europe PMC" ;   PMID:2784905 "Europe PMC" ;   PMID:2948307 "Europe PMC" ;   PMID:7914868 "Europe PMC" ;   PMID:8349948 "Europe PMC" ;   PMID:8894806 "Europe PMC" ;   PMID:9106068 "Europe PMC" ;   PMID:9180163 "Europe PMC" ;   PMID:9263386 "Europe PMC"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.