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Term:
specialised pro-resolving mediator (CHEBI:140399)
Annotations: Rat: (34) Mouse: (35) Human: (35) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
biological role +     
(+)-alpha-viniferin  
(+)-conocarpan  
(+)-schisandrin B  
(+)-subersic acid 
(-)-antofine  
(-)-cubebin 
(-)-larreatricin 
(-)-syringaresinol O,O'-bis(beta-D-glucoside) 
(10E,12Z,15Z)-9-hydroxy-10,12,15-octadecatrienoic acid methyl ester 
(13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid 
(18R)-resolvin E3 
(18S)-resolvin E1 
(18S)-resolvin E2 
(1R,5R,6S,7R,8S,10R)-8-hydroxy-4-oxopseudoguai-2(3),11(13)-dien-12,6-olide 
(1R,5R,6S,7S,8S,10R,11S)-6-hydroxy-4-oxopseudoguai-2(3)-en-12,8-olide 
(1S,2R,5R,6S,7R,8S,10R)-6-acetoxy-2-methoxy-4-oxopseudoguai-11(13)-en-12,8-olide 
(1S,2R,5R,6S,7S,8S,10R)-6-hydroxy-2-ethoxy-4-oxopseudoguai-11(13)-en-12,8-olide 
(1S,2R,5R,6S,7S,8S,10R)-6-hydroxy-2-methoxy-4-oxopseudoguai-11(13)-en-12,8-olide 
(1S,2S,5R,6S,7R,8S,10R)-6-acetoxy-2-methoxy-4-oxopseudoguai-11(13)-en-12,8-olide 
(1S,5R,6S,7S,8S,10R,11R)-6-hydroxy-4-oxopseudoguai-12,8-olide 
(1S,5S,7R,8S,10R)-14-acetoxy-4-oxopseudoguai-11(13)-en-12,8-olide 
(2S,3S)-2,3-dihydro-3-hydroxymethyl-2-(4-hydroxyphenyl)-5-(E)-propenylbenzofuran 
(4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid 
(4Z,7Z,10Z,12E,14R,16Z,19Z)-14,22-dihydroxydocosahexaenoic acid 
(4Z,7Z,10Z,12E,14S,16Z,19Z)-14,22-dihydroxydocosahexaenoic acid 
(4Z,7Z,10Z,13Z,15E,19Z)-17-oxodocosahexaenoic acid 
(5Z)-5-(quinoxalin-6-ylmethylidene)-1,3-thiazolidine-2,4-dione 
(5Z,11Z,14Z)-icosatrienoic acid 
(7R,14S)-dihydroxy-(4Z,8E,10E,12Z,16Z,19Z)-docosahexaenoic acid 
(7R,14S)-dihydroxy-(8E,10E,12Z,16Z,19Z)-docosapentaenoic acid 
(E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside 
(R)-lisofylline +  
(RS)-mallotophilippen E 
1,3,7,9-tetramethyluric acid 
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one 
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one 
1-O-3,4-dimethoxy-5-hydroxyphenyl-(6-O-3,5-dimethoxygalloyl)-beta-D-glucopyranoside 
1-O-3,4-dimethoxy-5-hydroxyphenyl-(6-O-vanilloyl)-beta-D-glucopyranoside 
10-PAHSA 
10-PAHSA(1-) 
11(R)-HEPE 
11(R)-HEPE(1-) 
11-PAHSA 
11-PAHSA(1-) 
12-PAHSA 
12-PAHSA(1-) 
13,14(S)-dihydroxy-(7Z,9E,11E,16Z,19Z)-docosapentaenoic acid 
13-PAHSA 
13-PAHSA(1-) 
14(S),21-dihydroxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoic acid 
15(R)-HEPE 
15(R)-HEPE(1-) 
16(S)-HETE 
16,23,29-trihydroxy-3-oxo-olean-12-en-28-oic acid 
17-defurano-17-oxosalannin 
18(R)-HEPE 
18(R)-HEPE(1-) 
18(S)-HEPE 
19alpha-hydroxyasiatic acid +  
2',4,4',6'-tetrahydroxychalcone +   
2',4,4',6'-tetrahydroxychalcone(1-) 
2'-hydroxychalcone  
2'-hydroxydaidzein 
2'-hydroxydaidzein(1-) 
2'-hydroxyformononetin 
2'-phospho-cyclic ADP-ribose 
2,4-dihydroxy-6-methylbenzaldehyde 
2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran 
2-(2-hydroxy-4-methoxyphenyl)-5-(3-hydroxypropyl)benzofuran 
2-(4-hydroxyphenyl)-5-(E)-propenylbenzofuran 
2-(beta-D-glucopyranosyloxy)benzoic acid 
2-acetamidophenol  
2-heptyl-3-hydroxy-4-quinolone 
2-heptyl-4-hydroxyquinoline 
2-heptyl-4-quinolone 
22-hydroxyprotectin D1 
2alpha,3alpha,23-trihydroxyolean-12-en-28-oic acid 
2alpha,3beta-dihydroxyolean-13(18)-en-28-oic acid 
2alpha-acetoxy-4alpha,6alpha-dihydroxy-1beta,5alphaH-guai-9(10),11(13)-dien-12,8alpha-olide 
3',5'-cyclic UMP 
3,4'-dimethylkaempferol 
3-deacetylsalannin 
3-O-[2,3-di-O-acetyl-alpha-L-arabinopyranosyl]-hederagenin 28-O-alpha-L-rhamnopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranoside 
3-O-[3,4-di-O-acetyl-alpha-L-arabinopyranosyl]hederagenin 28-O-alpha-L-rhamnopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranoside 
3beta,6beta,23-trihydroxyolean-12-en-28-oic acid 
3beta,6beta,23-trihydroxyolean-12-en-28-oic acid 28-O-beta-D-glucopyranoside 
4',6,7-trihydroxyisoflavone 
4'-hydroxychalcone  
4-epiisoinuviscolide 
4-hydroxycordoin 
4-terpineol +   
4beta,10alpha-dihydroxy-5alphaH-guai-1(2),11(13)-dien-12,8alpha-olide 
5-(3-hydroxypropyl)-2-(2-methoxy-4-hydroxyphenyl)benzofuran 
5-PAHSA 
5-PAHSA(1-) 
6'-O-acetylpaeoniflorin 
6,7-dihydroxy-4-methylcoumarin 
7-deacetylgedunin 
7-epiclusianone 
7-oxo-10alpha-cucurbitadienol 
7-PAHSA 
7-PAHSA(1-) 
7alpha-hydroxydehydroepiandrosterone 
8-epihelenalin 
8-epiinuviscolide 
8-nitroguanosine 3',5'-cyclic monophosphate 
8-oxoresolvin D1 
8-PAHSA 
8-PAHSA(1-) 
9-PAHSA 
9-PAHSA(1-) 
9E,11E-octadecadienoic acid +   
absinthin 
acteoside  
aetiopathogenetic role +   
afzelin  
agnuside 
all-trans-retinoic acid +   
Aloe C-glucosylchromone 
alpha-D-GalN-(1->4)-[alpha-DD-Hep-(1->2)]-alpha-D-GalA-yl group 
anti-inflammatory drug +   
antigen +   
antimicrobial agent +   
antimutagen +   
antrocapmphin A 
aromaticin 
ascidiathiazone A 
ascidiathiazone B 
aspirin-triggered protectin D1 
aspirin-triggered resolvin D1 
aspirin-triggered resolvin D2 
aspirin-triggered resolvin D3 
aspirin-triggered resolvin D4 
aspirin-triggered resolvin D5 
aspirin-triggered resolvin D6 
astilbin  
astragaloside IV  
autoinducer +   
azadiradione +   
baicalein +   
bauhinoxepin F 
bauhinoxepin I 
BAY 60-6583  
beraprost  
beraprost sodium 
beta-lapachone  
beta-myrcene  
betamethasone phosphate 
betulin +   
betulinic acid +   
biochemical role +   
biophysical role +   
bixin +   
bowdichione 
brazilein  
brazilin  
bufalin  
burrodin 
butrin 
c-di-GMP  
cafestol  
cannabigerol  
capsiate  
carbon monoxide  
carlinoside 
carnosic acid  
carpesiolin 
castanospermine 
cauloside D 
cenicriviroc 
CGP-42112A  
CGS-21680  
chrysin +   
chrysophanol +   
clarinoside 
cleomiscosin A 
columbianadin 
conferol A 
conferol B 
confertin 
CORM 3 
coumestrol +   
crassumolide A 
cryogenine 
cryptolepine  
cudraflavone B  
cudratricusxanthone A 
curcumin +   
cyclo(L-His-L-Pro) 
cyclomontanin A 
cyclomontanin C 
cyclomontanin D 
decane-1,2-diol 
decanoic acid +   
dehydrodiconiferyl alcohol +  
Delta(9)-tetrahydrocannabinolic acid  
demethoxycurcumin  
demethylzeylasteral 
diallyl trisulfide  
diinsinin 
diinsininol 
dioscin  
diosmin  
dipsacussaponin A 
EI-1511-3 
EI-1511-5 
EI-1625-2 
epi-maslinic acid 
epicatechin 3-O-(3'-O-methylgallate) 
epitope +   
epoxyazadiradione +  
ergolide 
ethyl linoleate 
ethyl trans-caffeate  
eupatilin  
eupatorin  
fangchinoline  
farnesoic acid +   
ferulic acid +   
fisetin +   
fixative +   
flavalin A 
flavokawain B  
floribundasaponin A 
fluorogen +  
fraxetin +   
fraxin 
gamma-aminobutyric acid +   
Genipin  
ginsenoside C-K  
ginsenoside Re  
glutathione depleting agent +   
gordonoside I 
gordonoside J 
gordonoside K 
gordonoside L 
gordonoside M 
gordonoside N 
gordonoside O 
gordonoside P 
grandiflorenic acid 
graveolide 
growth regulator +   
hapten +   
hederagenin 28-O-beta-D-glucopyranoside 
helenalin  
herbacetin  
hispidulin  
HU-308  
Human Antigen R Protein Expression Modulator and AkT Inhibitor 
hydrogen sulfide +   
hydroxysafflor yellow A  
hyperforin  
icariside II  
ilomastat  
immunomodulator +   
incretin mimetic +  
indicanone 
inhibitor +   
insect attractant +   
inuchinenolide B 
inuchinenolide C 
inuviscolide  
isobutrin 
jaceosidin  
JQ1 
JWH-133 
kaempferol 3,7-di-O-alpha-L-rhamnoside 
kahweol  
kalopanaxsaponin A  
kalopanaxsaponin B 
kalopanaxsaponin C 
klymollin C 
klymollin D 
klymollin E 
klymollin F 
klymollin G 
klymollin H 
kurarinol  
kuwanone G  
leukotriene B5  
liquiritin  
loganin +   
lupulin A 
luteolin +   
macabarterin 
madecassoside  
magnoshinin 
mallotophilippen A 
mallotophilippen B 
mallotophilippen C 
mallotophilippen D 
mangicol A 
mangiferin  
mannioside A 
maslinic acid +   
meso-3,3'-didemethoxynectandrin B 
meso-zeaxanthin 
methyl 3,4,5-trihydroxybenzoate  
methyl 4,23,29-trihydroxy-3,4-seco-olean-12-en-3-oate-28-oic acid 
methylprednisolone suleptanate 
miltefosine  
mimotope +  
minabeolide 1 
minabeolide 2 
minabeolide 4 
minabeolide 5 
minabeolide 8 
mitogen +   
molecular messenger +   
monascorubrin 
monotropein  
morin  
multifidol glucoside 
myo-inositol hexakisphosphate  
myrsinoic acid A 
myrsinoic acid B 
myrsinoic acid C 
myrsinoic acid F 
N-(4-coumaroyl)-L-homoserine lactone 
N-arachidonoylserotonin 
N-isovaleryl-L-homoserine lactone 
naringin  
narirutin 
neophytadiene 
nicotinamide +   
nicotinic acid-adenine dinucleotide phosphate  
nitric oxide  
nodulation factor +  
oleocanthal 
oleuropein +   
oleuropein aglycone 
ombuin 
orobol +  
osmolyte +   
ospemifene  
palmitoleoyl ethanolamide 
pectolinarin 
pentamidine  
PH 797804 
pharmacological role +   
phenethyl caffeate  
physcion +   
physiological role +   
piclamilast  
pinellic acid 
piperlactam S 
PMX-205 
poison +   
praliciguat 
prednisolone phosphate 
prednisolone sodium phosphate 
procyanidin B1 +  
procyanidin B3 +   
procyanidin C1 
prohormone +   
protectin D1 +  
provitamin +   
prunetin +   
pterolinus A 
pterolinus B 
pterolinus D 
quillaic acid +  
rac-lisofylline 
rataniaphenol I 
rataniaphenol II 
rataniaphenol III 
rel-2alpha,3alpha,23-trihydroxy-19-oxo-18,19-seco-urs-11,13(18)-dien-28-oic acid 
rel-2alpha,3beta,23-trihydroxy-19-oxo-18,19-seco-12,17-dien-28-norursane 
resolvin D1  
resolvin D1(1-) 
resolvin D2  
resolvin D3 
resolvin D4 
resolvin D5 
resolvin D6 
resolvin E1 
resolvin E1(1-) 
resolvin E2 
resolvin E3 
resolvin T1 
resolvin T2 
resolvin T3 
resolvin T4 
rhamnetin 
rohitukine 
rosuvastatin  
rosuvastatin calcium  
rubimaillin  
S-nitrosoglutathione  
salvianolic acid B  
sappanchalcone  
SB220025 
sclerotherapy agent +  
sieboldianoside A 
sigmoidin A 
sigmoidin B 
sirtinol  
sodium aurothiomalate  
sodium ferulate 
specialised pro-resolving mediator +   
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
sphingosine 1-phosphate  
stevioside +   
swertisin 
talosin A 
taraxasterol 
tauroursodeoxycholic acid  
TDZD-8 
tectorigenin +   
theophylline +   
thionitrous acid 
thymoquinone  
tideglusib 
tilorone 
tilorone dihydrochloride 
tissue adhesive +  
tolerogen +  
toluquinol 
tolypodiol 
trabectedin  
trilobatin  
triptonide  
triptriolide 
tropisetron  
tropisetron hydrochloride 
tropodithietic acid 
tyrphostin B42  
U69593  
vestitol +  
viridiflorol 
visnagin 
xenobiotic +   
zerumbone +   
zhankuic acid A +  
zingerone  

Synonyms
Related Synonyms: SPM ;   SPMs ;   specialised pro-resolving mediators ;   specialised proresolving mediator ;   specialised proresolving mediators ;   specialized pro-resolving mediator ;   specialized pro-resolving mediators ;   specialized proresolving mediator ;   specialized proresolving mediators
Xrefs: Wikipedia:Specialized_pro-resolving_mediators

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.