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Term:
Parent Terms Term With Siblings Child Terms
(2-chlorophenyl)(4-fluorophenyl)pyrimidin-5-ylmethanol +   
(2R)-[(4-carbamimidoylphenyl)amino]\{5-ethoxy-2-fluoro-3-[(3R)-tetrahydrofuran-3-yloxy]phenyl\}acetic acid 
1',4-dihydroxymidazolam 
1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol +  
1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea 
1-(4-fluorophenyl)-7-(4-methylphenyl)-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione 
1-\{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl\}-1H-1,2,4-triazole +   
1-bromo-4-fluorobenzene 
1-hydroxymidazolam +   
1-hydroxymidazolam beta-D-glucuronide  
2,2,4-trimethyl-3-(4-fluorophenyl)-2H-1-benzopyran-7-ol acetate 
2-(1,3-benzothiazol-2-yl)-4-fluorophenol +  
2-(2,4-dichlorobenzoylamino)-5-(pyrimidin-2-yloxy)benzoic acid 
2-(2-amino-3-methoxyphenyl)chromen-4-one 
2-(4-fluorophenyl)-1-(1,2,4-triazol-1-yl)-3-(trimethylsilyl)propan-2-ol +  
2-(ethoxymethyl)-4-(4-fluorophenyl)-3-[2-(2-hydroxyphenoxy)pyrimidin-4-yl]isoxazol-5(2H)-one 
2-[5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione +  
2-\{4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy\}-N-(2-fluorophenyl)-N-methylpropanamide +  
2-chloro-3-\{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl\}propanoic acid +  
2-fluoro-6-(4-methoxyphenoxy)benzonitrile 
2-fluorophenylalanine +  
3',4'-difluoro-N-\{4'-fluoro-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-yl\}-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-carboxamide 
3-(\{[(2S)-5-oxopyrrolidin-2-yl]methyl\}sulfonyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-L-alanin[N-(1-cyanocyclopropyl)]amide 
3-chloro-4-[(2-fluorobenzyl)oxy]benzaldehyde oxime 
3-fluoro-5-morpholin-4-yl-N-[1-(2-pyridin-4-ylethyl)-1H-indol-6-yl]benzamide 
3-fluoro-D-tyrosine 
3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-\{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl\}-L-phenylalaninamide 
3-fluorobenzaldehyde 
3-fluorobenzyl alcohol 
3-fluorocatechol 
4,4'-pentane-2,3-diylbis(2-fluorophenol) +  
4-(1,3-benzodioxol-5-yloxy)-2-[4-(1H-imidazol-1-yl)phenoxy]-6-methylpyrimidine 
4-(1,3-benzodioxol-5-yloxy)-2-[4-(1H-imidazol-1-yl)phenoxy]pyrimidine 
4-(4-fluorophenoxy)-3-nitrobenzaldehyde oxime 
4-[4-(4-fluorophenyl)-1-piperidin-4-yl-1H-imidazol-5-yl]pyrimidin-2-amine 
4-\{1-methyl-2-piperidin-4-yl-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl\}-N-[(1S)-1-phenylethyl]pyrimidin-2-amine 
4-fluorophenol 
4-fluorophenylalanine +  
4-hydroxymidazolam +   
4-hydroxymidazolam beta-D-glucuronide 
4-methyl-N-[3-(morpholin-4-yl)phenyl]-3-[3-(piperidin-4-yl)-1,2-benzoxazol-6-yl]benzamide 
4-phenoxy-N-(pyridin-2-ylmethyl)benzamide 
5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate +  
6-[[1-[(4-fluorophenyl)methyl]-2-pyrrolyl]methylidene]-5-imino-7-thiazolo[3,2-a]pyrimidinone 
9-(4-hydroxyphenyl)-2,7-phenanthroline 
9-cyclopentyl-N(8)-(2-fluorophenyl)-N(2)-(4-methoxyphenyl)-9H-purine-2,8-diamine 
abamine 
aspirin-based probe AP 
atorvastatin 
auraptene  
azaperone  
azoxystrobin  
azoxystrobin acid 
BAY 41-2272 
bencarbazone 
binimetinib 
bis(3-fluorobenzylidene)hydrazine 
broflanilide 
c-Jun N-terminal kinase inhibitor +   
cercosporamide 
CH5126766 
cobimetinib  
cobimetinib fumarate 
cyproflanilide 
dacomitinib  
dafadine B 
didesethylflurazepam 
difloxacin 
doramapimod  
enzalutamide 
eribaxaban 
florpyrauxifen +  
florpyrauxifen-benzyl 
florylpicoxamid 
flufenacet  
flufenacet ESA 
flufenacet OXA 
flufenoxuron 
flufenpyr +  
flufenpyr-ethyl 
flunitrazepam  
fluoroimide 
flurazepam +   
flusilazole  
fluthiacet +  
fluthiacet-methyl 
flutianil 
flutrimazole 
G-573 
gefitinib +   
gevotroline 
GNF6702 
halauxifen +  
halauxifen-methyl 
hydroxyethylflurazepam 
hypothemycin 
JQ1 
lorlatinib 
LY-310762 
m-fluoro-L-phenylalanine 
marbofloxacin  
MC1568  
methyl \{[2-chloro-4-fluoro-5-(1-oxo-3-sulfanylidenetetrahydro-1H-[1,2,4]triazolo[1,2-a]pyridazin-2(3H)-yl)phenyl]sulfanyl\}acetate 
MI-63 
midazolam +   
monofluorobenzene +   
N-(3-\{[2-(2-fluorophenyl)quinazolin-4-yl]amino\}phenyl)acetamide 
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide 
N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide 
N-(3-fluorophenyl)-2-(pyridin-4-yl)quinazolin-4-amine 
N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide +   
N-benzyl-2-[4-fluoro-3-(trifluoromethyl)phenoxy]butanamide +  
N-cyclohexyl-4-[4-(3,4-dichlorophenyl)-2-piperidin-4-yl-1-propyl-1H-imidazol-5-yl]pyrimidin-2-amine 
N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide 
N-cyclopropyl-3-\{4-[(cyclopropylmethyl)carbamoyl]phenyl\}-4-methylbenzamide 
N-cyclopropyl-3-\{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydropyrazolo[3,4-b]pyridin-4-yl]amino\}-4-methylbenzamide 
N-cyclopropyl-4-[4-(3,4-dichlorophenyl)-2-(1-methylpiperidin-4-yl)-1-propylimidazol-5-yl]pyrimidin-2-amine 
N-desmethylenzalutamide 
N-methylparoxetine 
nelociguat 
olaparib  
p-fluoro nygerone B 
pamapimod 
PD 0325901  
pentoxazone 
PF-670462 free base 
PH 797804 
picolinafen 
pimavanserin 
pitavastatin  
praliciguat 
pyraflufen +  
pyraflufen-ethyl 
pyridin-3-ylmethyl \{4-[(2-amino-4-fluorophenyl)carbamoyl]benzyl\}carbamate 
quinoxyfen  
regorafenib +   
Ro 48-8071 
RO4927350 
rosuvastatin  
saflufenacil 
sapitinib 
SB 203580  
SB-202190 
SB-239063  
SB-245391 
SB-284851-BT 
A piperidinylimidazole that is 1H-imidazole carrying a piperidin-4-yl group, 4-fluorophenyl group and a 2-(3,5-dimethylphenoxy)pyrimidin-4-yl group at positions 1, 4 and 5 respectively. It is a potent inhibitor of p38alpha mitogen-activated protein kinase and BRD4.
SB220025 
selumetinib  
SKLB-677 
talmapimod 
trametinib +   
trametinib dimethyl sulfoxide 
trans-Ned 19 
U0126 +   
U0126.EtOH 
VX-745  
ZM 323881 

Synonyms
Exact Synonyms: 2-(3,5-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidine
Related Synonyms: 2-(3,5-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl]pyrimidine ;   Formula=C26H26FN5O ;   InChI=1S/C26H26FN5O/c1-17-13-18(2)15-22(14-17)33-26-29-12-9-23(31-26)25-24(19-3-5-20(27)6-4-19)30-16-32(25)21-7-10-28-11-8-21/h3-6,9,12-16,21,28H,7-8,10-11H2,1-2H3 ;   InChIKey=UVLWMBRFRAMDOW-UHFFFAOYSA-N ;   SB-284851 ;   SB284851BT ;   SMILES=CC1=CC(C)=CC(OC2=NC=CC(C3=C(C4=CC=C(F)C=C4)N=CN3C5CCNCC5)=N2)=C1
Xrefs: PMID:11354358 ;   PMID:26158404

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.