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Ontology Browser

Term:
12-hydroxynevirapine (CHEBI:145206)
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Parent Terms Term With Siblings Child Terms
cyclopropanes +     
dipyridodiazepine +     
nevirapine +   
(+)-(1S,2S)-norcoronamic acid 
(1,2,3-trimethyl-2-cyclopropen-1-yl)benzene 
(13R)-13-dihydrocarminomycin 
(1R,2S)-nortilidine +  
(1S,2R)-nortilidine +  
(2,3-diphenylcyclopropyl)methyl phenyl sulfoxide 
(22E)-24,26-cyclo-19-norcholesta-1,3,5(10),22-tetraen-3-ol 
(2S)-2-(4-\{[(1R,2S)-2-hydroxycyclopentyl]methyl\}phenyl)propanoic acid 
(2S,4R)-hypoglycin B +  
(2S,4S)-hypoglycin B +  
(5-hydroxyindol-3-yl)acetic acid  
(6-methoxy-2-naphthyl)acetic acid 
(7R,8R)-AGI-B4 
(R,R)-chrysanthemal +   
1',4-dihydroxymidazolam 
1,1,1,3,3,3-hexafluoropropan-2-ol  
1-(2-methylenecyclopropyl)ethanone 
1-(3-chlorophenyl)piperazine  
1-bromo-4-cyclopropylbenzene 
1-hydroxymidazolam +   
1-hydroxymidazolam beta-D-glucuronide  
1-methylidene-2-(pent-4-en-1-yl)cyclopropane 
10,11-trans-dihydroxy-10,11-dihydrocarbamazepine +  
12-hydroxynevirapine 
A dipyridodiazepine that is nevirapine in which one of the hydrogens of the methyl group has been substituted by a hydroxy group. It is a metabolite of the anti-HIV drug, nevirapine.
2,6-dimethylaniline +   
2-(3,5-dichlorophenylcarbamoyl)-1,2-dimethylcyclopropane-1-carboxylic acid 
2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol +   
2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione +   
2-amino-3-(2-methylenecyclopropyl)propanoic acid +  
2-cyano-3-cyclopropyl-1-(2-mesyl-4-trifluoromethylphenyl)propan-1,3-dione 
2-formylbenzoic acid 
2-hydroxy-3-(2-methylidenecyclopropyl)butanedioic acid 
2-hydroxy-4-hydroxymethylbenzylidenepyruvic acid 
2-hydroxyibuprofen 
2-methoxyacetaminophen glucuronide 
2-methoxyacetaminophen glucuronide(1-) 
2-methoxyacetaminophen sulfate 
2-methoxyacetaminophen sulfate(1-) 
2-phenylcyclopropan-1-amine +   
26,27-dehydrozymosterol 
3'-hydroxy-4'-methoxydiclofenac 
3'-hydroxydiclofenac 
3,4-dihydroxymandelic acid  
3,5-dihydroxyphenylacetic acid 
3-chlorobenzoic acid 
3-hydroxy-2,2-dimethylbutyric acid 
3-hydroxymethylantipyrine 
3-pyridinemethanol  
3beta-hydroxy-9beta-9,19-cyclolanost-24-en-28-oic acid 
4',5-dihydroxydiclofenac 
4'-hydroxydiclofenac  
4-(acetylamino)-3-hydroxyphenyl hydrogen sulfate 
4-(acetylamino)-3-hydroxyphenyl sulfate 
4-(methylamino)antipyrine 
4-(trifluoromethyl)phenol 
4-acetamidoantipyrine 
4-amino-5-hydroxymethyl-2-methylpyrimidine 
4-aminoantipyrine 
4-ethoxyaniline +   
4-formylaminoantipyrine 
4-hydroxy-2,6-dimethylaniline 
4-hydroxy-6-methylaniline 
4-hydroxymethylsalicylaldehyde 
4-hydroxymidazolam +   
4-hydroxymidazolam beta-D-glucuronide 
4-hydroxypropofol 
5'-hydroxyomeprazole  
5-(hydroxymethyl)cytosine +   
5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine +  
5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate +  
5-carboxy-2'-deoxyuridine 
5-fluorouridine 5'-monophosphate 
5-hydroxydiclofenac  
5-hydroxydiclofenac quinone imine 
5-hydroxymethyl-2-furoic acid 
5-O-desmethyldonepezil 
5alpha,8alpha-epidioxysterol 
6-azauridine +   
7-hydroxyticlopidine 
\{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl\}methanol +  
acetaminophen O-beta-D-glucosiduronic acid  
acetohydrazide +   
ACT-132577 +   
ACT-333679 +  
adefovir +   
alloxanthine +   
Aloe emodin  
aminocyclopyrachlor +  
aripiprazole  
aspergillusone B 
atenolol acid 
atenolol-desisopropyl 
azure B  
BAY 41-2272 
BAY 60-6583  
beta-(methylenecyclopropyl)pyruvic acid 
brevipolide A 
brevipolide B 
calcipotriol +   
carbamazepine-10,11-epoxide  
carboxyibuprofen 
carboxyibuprofen(2-) 
ceftaroline +  
chrysanthemic acid +   
chrysanthemol +   
ciprofibrate  
clopidogrel carboxylic acid 
CNDAC +  
coprine 
cotinine N-oxide 
cyclopropane +  
cyclopropanecarboxylate ester +   
cyclopropanecarboxylic acid +   
cyclopyrimorate 
cyclosporin A metabolite M1 +  
cyclosporin A metabolite M10 
cyclosporin A metabolite M13 
cyclosporin A metabolite M16 +  
cyclosporin A metabolite M17 +  
cyclosporin A metabolite M18 +  
cyclosporin A metabolite M1A 
cyclosporin A metabolite M1cAL 
cyclosporin A metabolite M21 +  
cyclosporin A metabolite M25 
cyclosporin A metabolite M26 
cyclosporin A metabolite M8 +  
cyclosporin A metabolite M9 
cyprodinil  
cyprosulfamide 
D617 
desmethyl loperamide 
desmethyldoxepin +  
desmethylnaproxen  
desmethylnaproxen sulfate 
desmethylnaproxen(1-) 
desmethylranitidine 
diclofenac beta-D-glucosiduronic acid 
didesethylflurazepam 
dihydropyriculariol 
dioxoaminopyrine 
doxorubicinol 
E-3810 free base 
efavirenz  
enrofloxacin  
epsilon-metofluthrin 
epsilon-momfluorothrin 
ethisterone 
ethyl 1-allylcyclopropanecarboxylate 
fenofibric acid 
finafloxacin 
firocoxib 
flucycloxuron +  
FR171456 
garenoxacin 
gentisyl alcohol 
glycinexylidide +  
grazoprevir +  
GSK1016790A 
heptafluthrin 
hydroxyalbendazole 
hydroxyfenbendazole 
imidaprilat  
imiprothrin 
indometacin +   
irgarol 1051 
isoxaflutole 
ixazomib +   
kappa-bifenthrin 
L-alpha-(methylidenecyclopropyl)glycine 
lenvatinib 
lesinurad 
lificiguat 
lumacaftor +   
methyl cyclopropanecarboxylate 
mevinolinic acid 
MLI-2 
monoethylglycinexylidide +   
moxifloxacin  
N,N-didesmethylvenlafaxine 
N,O-didesmethylvenlafaxine 
N-(2-[(2-aminoethyl)(methyl)amino]-5-\{[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino\}phenyl)acetamide 
N-\{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl\}-3-(difluoromethyl)-1-methyl-1pyrazole-4-carboxamide +  
N-acetylsulfamethoxazole 
N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide 
N-cyclopropyl-3-\{4-[(cyclopropylmethyl)carbamoyl]phenyl\}-4-methylbenzamide 
N-cyclopropyl-3-\{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydropyrazolo[3,4-b]pyridin-4-yl]amino\}-4-methylbenzamide 
N-cyclopropyl-4-[4-(3,4-dichlorophenyl)-2-(1-methylpiperidin-4-yl)-1-propylimidazol-5-yl]pyrimidin-2-amine 
N-desmethylvenlafaxine 
N-substituted pyrraline +  
naltrexone  
nevirapine +   
nitrazepam +   
nitrososulfadiazine 
nitrososulfapyridine 
norfentanyl 
nortriptyline  
norverapamil  
O-desethyl candesartan 
O-desmethylvenlafaxine 
olaparib  
oxidopamine  
oxyphenbutazone +   
paliperidone 
paracetamol sulfate +   
paritaprevir +  
perindoprilat 
permethrin +   
PHA-533533 
pitavastatin  
prallethrin  
prednisolone +   
procainamide 4-hydroxylamine 
proglumide +  
promazine sulfoxide 
psilocin +  
pyrazine-2-carboxylic acid  
pyridine N-oxide +   
pyrraline +  
rac-nortilidine 
ramiprilat  
ranitidine N-oxide 
ranitidine-S-oxide 
ritalinic acid  
roflumilast  
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteinate 
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteine 
salicin +   
salicyl alcohol +   
SN-38 +   
spiraprilat +   
sulfadiazine hydroxylamine 
sulfapyridine hydroxylamine 
tasimelteon 
tedizolid 
telaprevir  
tenofovir (anhydrous) +   
teriflunomide  
theophylline  
tralomethrin  
trametinib +   
trandolaprilat 
transfluthrin  
trinexapac +  
trinexapac-ethyl 
triptohypol A 
uridine +   
variecoxanthone C 
WR-1065  
zofenoprilat 

Synonyms
Exact Synonyms: 11-cyclopropyl-4-(hydroxymethyl)-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Related Synonyms: 11-cyclopropyl-4-(hydroxymethyl)-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one ;   12-OH-NVP ;   12-hydroxy-NVP ;   12-hydroxy-nevirapine ;   Formula=C15H14N4O2 ;   InChI=1S/C15H14N4O2/c20-8-9-5-7-17-14-12(9)18-15(21)11-2-1-6-16-13(11)19(14)10-3-4-10/h1-2,5-7,10,20H,3-4,8H2,(H,18,21) ;   InChIKey=SEBABOMFNCVZGF-UHFFFAOYSA-N ;   N(11)-cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido(3,2-b:2,3-e)(1,4)diazepin-6-one ;   SMILES=O=C1NC=2C(N(C3CC3)C=4N=CC=CC41)=NC=CC2CO
Xrefs: CAS:133627-24-4 "ChemIDplus" ;   HMDB:HMDB0013911 ;   PMID:10421616 "Europe PMC" ;   PMID:17618842 "Europe PMC" ;   PMID:18042504 "Europe PMC" ;   PMID:18597499 "Europe PMC" ;   PMID:20392079 "Europe PMC" ;   PMID:23459477 "Europe PMC" ;   PMID:23590230 "Europe PMC" ;   PMID:23947594 "Europe PMC" ;   PMID:24051761 "Europe PMC" ;   PMID:25275777 "Europe PMC" ;   PMID:25394082 "Europe PMC" ;   PMID:26620700 "Europe PMC" ;   PMID:29309900 "Europe PMC" ;   PMID:30028994 "Europe PMC"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.