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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
dithiolanes +     
thia fatty acid +     
(+)-pentacycloanammoxic acid +  
(2S,3R,4S)-4-[(2S,7S,8R,9S)-2-[(5S)-5-ethyl-5-[(3S,5R)-5-[(3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2-oxanyl]-3-methyl-2-oxolanyl]-2-oxolanyl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methylpentanoic acid 
(3S,4S)-3-hydroxy-4-methyloctanoic acid +  
(7R)-7-hydroxyoctanoic acid +  
(R)-lipoic acid +   
(R)-lipoyl-GMP 
(S)-lipoic acid +  
1,2-dioctanoyl-3-beta-D-galactosyl-sn-glycerol 
1,3-dioctanoylglycerol 
1,4-butanediammonium 
1-O-(alpha-D-galactopyranosyl)-N-octanoylphytosphingosine 
1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine 
2'-deoxyadenosine 5'-monophosphate +  
2'-deoxyadenosine 5'-monophosphate(2-) +  
2-(pentylsulfanyl)acetic acid +  
2-cyano-N-(2,4-dichlorophenyl)-3-[5-(2-methylcyclopropyl)-2-furanyl]-2-propenamide 
2-deoxy-D-ribofuranose 1-phosphate +   
2-hydroxy-4-(methylthio)butanoic acid 
2-hydroxyoctanoic acid +  
2-O-[6-O-octanoyl-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl]-D-glyceric acid 
2-octanoyl-sn-glycero-3-phosphocholine 
2-oxoglutarate(1-) 
2-oxoglutaric acid +  
3-(methylthio)propionic acid +  
3-aminooctanoic acid 
3-hydroxyoctanoic acid +  
3-methylbutyl octanoate 
3-oxooctanoic acid +  
3-phosphoglyceric acid +   
3-phosphonato-D-glycerate(3-) 
4,7-dioxooctanoic acid 
4-(4-chlorophenyl)-1-\{3-[2-(4-fluorophenyl)-1,3-dithiolan-2-yl]propyl\}piperidin-4-ol 
4-(4-ethyl-1-piperazinyl)-4-oxo-2-butenoic acid 
6-hydroxy-3,7-dimethyloctanoic acid +  
6-phospho-D-gluconic acid 
6-phosphonatooxy-D-gluconate 
8-(5-hexylfuran-2-yl)octanoic acid 
8-[(1R,2R)-3-oxo-2-\{(Z)-pent-2-en-1-yl\}cyclopentyl]octanoic acid 
8-hydroxyoctanoic acid +   
acetyl-CoA +   
adenosine +   
adenosine 5'-monophosphate +   
adenosine 5'-monophosphate(1+) 
adenosine 5'-monophosphate(2-) +  
ADP +   
ADP(3-) +  
alanine +   
aldehydo-D-ribose 5-phosphate(2-) 
all-trans-retinyl octanoate 
alpha-D-glucose 1-phosphate(2-) 
alpha-D-glucose 6-phosphate(2-) 
alpha-D-mannose 6-phosphate(2-) 
alpha-L-galactose 1-phosphate(2-) 
arabinose +  
arginine +   
asparagusate 
asparagusic acid 
aspartate(1-) +  
aspartate(2-) +  
aspartic acid +   
ATP +   
ATP(3-) 
ATP(4-) +  
beta-alaninate 
beta-alanine +   
beta-D-fructofuranose 6-phosphate(2-) 
beta-D-glucose 1-phosphate(2-) 
beta-D-glucose 6-phosphate(2-) +  
beta-L-galactose 1-phosphate(2-) 
Bisnorbiotin 
ciliatamide B 
cis-aconitic acid 
citrate(1-) +  
citrate(2-) +  
citrate(3-) +   
citric acid +   
cysteine +   
D-aspartate(1-) +  
D-cysteinate(1-) 
D-cysteinate(2-) 
D-cysteinium 
D-cysteinyl radical +  
D-erythro-isocitrate(3-) 
D-fructofuranose 1,6-bisphosphate(4-) +  
D-fructofuranose 1-phosphate(2-) +  
D-fructofuranose 6-phosphate(2-) 
D-fructose 1,6-bisphosphate +   
D-fructose 6-phosphate +  
D-galactopyranose 1-phosphate +   
D-glucopyranose 1-phosphate +   
D-glucopyranose 1-phosphate(2-) 
D-glucose 6-phosphate +   
D-mannopyranose 6-phosphate(2-) 
D-mannose 1-phosphate +  
D-mannose 6-phosphate +   
D-ribose +   
D-ribose 5-phosphate +   
D-ribulose 5-phosphate(2-) 
D-threo-isocitrate(3-) 
dGDP 
dihydrolipoic acid +   
dithiolane +   
dithiolanecarboxylic acid +  
dTMP +   
epoxy fatty acid +   
fructose +   
fructose 1-phosphate +  
fumarate(1-) +  
fumaric acid +   
galactose +   
glucose +   
glutamate(1-) +   
glutamate(2-) +  
glutamic acid +   
glutamine +   
glyceraldehyde +   
glycerate +  
glyceric acid +   
glycinate +   
glycine +   
glycine betaine +   
glycine betaine hydrate 
glycinium +  
glycolaldehyde +   
glycyl radical +  
guanosine +   
GW 0791 
homocysteinate +  
homocysteine +   
hypoxanthine +   
IDP 
isocitric acid +  
isoprothiolane +   
keto-phenylpyruvic acid +   
L-alaninate +  
L-alanine +   
L-alaninium +  
L-aspartate(1-) +  
L-aspartate(2-) +  
L-cysteinate(1-) +  
L-cysteinate(2-) 
L-cysteinium +  
L-cysteinyl radical +  
L-erythro-isocitrate(3-) 
L-galactose 1-phosphate +  
L-galactose 1-phosphate(2-) +  
L-homocysteine zwitterion 
L-ribulose 5-phosphate(2-) 
L-threo-isocitrate(3-) 
L-tyrosinate(1-) 
L-tyrosinate(2-) +  
L-tyrosine +   
L-tyrosinium +  
L-xylulose 5-phosphate(2-) 
Leinamycin 
lipoamide +   
lipoate +  
lipoic acid +   
A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position.
lipoyl group +  
lipoyl-AMP +  
malate(2-) +  
malic acid +   
mannose +   
methyl (+)-pentacycloanammoxate 
N(6)-(1,2-dicarboxyethyl)-AMP 
N,N,N-trimethylglycinium +  
N-(octanoyl)-L-homoserine 
N-(octanoyl)ethanolamine 
N-capryloyl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine 
N-octanoyl-(2S)-hydroxyglycine 
N-octanoylanthranilate 
N-octanoylanthranilic acid 
N-octanoyldihydrosphingosine 
N-octanoylglycine 
N-octanoylphytosphingosine 
N-octanoylsphingosine 
N-octanoylsphingosine 1-phosphate 
NAD +   
NADH +  
NADP zwitterion +   
NADP(+) +   
NADPH +  
nereistoxin 
octanamide 
octanoate ester +   
octanoyl group +  
octanoyl-CoA +  
oxalatosuccinate(3-) +  
oxalosuccinic acid +  
perfluorooctanoic acid  
pescaprein XXX 
phosphoenolpyruvate  
phosphoenolpyruvic acid 
phosphonatoenolpyruvate 
pseudouridine +  
purine +   
putrescine +   
pyruvate +  
pyruvic acid +   
ribulose 5-phosphate +  
S-adenosyl-L-homocysteinate 
S-adenosyl-L-homocysteine  
S-octanoyl-4'-phosphopantetheine 
S-octanoyl-L-cysteine 
serinate +  
serine +   
serinium +  
spermidine +   
spermidine(3+) +  
spermine +   
spermine(4+) 
succinate(1-) 
succinic acid +   
Technetium Tc 99m succimer 
thiamine(1+) diphosphate +  
trans-aconitate(3-) 
trans-aconitic acid 
UDP-alpha-D-glucose  
UDP-alpha-D-xylose 
uridine +   
Wyerone 
Wyerone acid 
xanthine +   
xylulose 5-phosphate +   
 (R)-lipoic acid +   
lipoamide +   

Synonyms
Exact Synonyms: 5-(1,2-dithiolan-3-yl)pentanoic acid
Related Synonyms: 1,2-dithiolane-3-pentanoic acid ;   1,2-dithiolane-3-valeric acid ;   5-(1,2-dithiolan-3-yl)valeric acid ;   5-(dithiolan-3-yl)valeric acid ;   5-[3-(1,2-dithiolanyl)]pentanoic acid ;   6,8-thioctic acid ;   6,8-thiotic acid ;   6-thioctic acid ;   6-thiotic acid ;   Acetate-replacing factor ;   Biletan ;   Formula=C8H14O2S2 ;   InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) ;   InChIKey=AGBQKNBQESQNJD-UHFFFAOYSA-N ;   SMILES=OC(=O)CCCCC1CCSS1 ;   Thioctansaeure ;   Thioctic acid ;   Thioctsaeure ;   Thioktsaeure ;   alpha-Liponsaeure ;   alpha-lipoic acid ;   liponic acid
Alternate IDs: CHEBI:146958 ;   CHEBI:25058 ;   CHEBI:6492
Xrefs: Beilstein:122410 ;   Beilstein:81853 ;   CAS:62-46-4 ;   DrugBank:DB00166 ;   Drug_Central:4732 ;   ECMDB:ECMDB01451 ;   Gmelin:720915 ;   KEGG:C00725 ;   KEGG:D00086
Xref Mesh: MESH:D008063
Xrefs: PMID:7519986 ;   PMID:7548757 ;   Reaxys:81853 ;   Wikipedia:Lipoic_acid ;   YMDB:YMDB00334
Cyclic Relationships: is_conjugate_acid_of CHEBI:30313

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.