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Ontology Browser

Term:
4,5-dihydrocortisone (CHEBI:23736)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
11-oxo steroid +     
20-oxo steroid +     
21-hydroxy steroid +     
3-oxo steroid +     
cortisone +   
(+)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-benzoyloxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(+)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-cinnamoyloxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(+)-(5E,12E,2S,3S,4S,9S,11S,15R)-3-cinnamoyloxylathyra-5,12-dien-15-ol-14-one 
(+)-cis-isohumulone 
(-)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-acetoxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-3-cinnamoyloxylathyra-6,12-diene-5,15-diol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-5-cinnamoyloxylathyra-6,12-diene-3,15-diol-14-one 
(-)-microdiplodiasolol 
(16alpha,20R,24R)-24N,25-carbamoyloxy-2,16,20-trihydroxycucurbita-1,5-diene-3,11,22-trione 2-O-beta-D-glucopyranoside 
(16alpha,20R,24S)-2,16,20,25-tetrahydroxy-24-methoxycucurbita-1,5-diene-3,11,22-trione 2-O-beta-D-glucopyranoside 
(17Z)-3,11-dioxopregna-4,17(20)-dien-21-oic acid methyl ester 
(1S)-1,23,25-trihydroxy-24-oxocalciol 
(1S)-1,25-dihydroxy-24-oxocalciol 
(20R)-17alpha,20-dihydroxycholesterol 
(22E,24R)-3beta,5alpha,9alpha-trihydroxyergosta-7,22-dien-6-one 
(22E,24R)-3beta,5alpha-dihydroxyergosta-7,22-dien-6-one 
(25R)-7alpha,26-dihydroxycholest-4-en-3-one 
(3S)-3-[(2S)-2-amino-4-hydroxy-3-oxobutyl]pyrrolidin-2-one 
(8S,9S,10R,11S,13S,14R,17R)-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 
(8S,9S,10R,11S,13S,14R,17S)-11-hydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one 
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 
(R)-blebbistatin 
(S)-2-acetyl-2-hydroxybutanoic acid 
(S)-blebbistatin 
1,3-dihydroxybutan-2-one 
1-hydroxybutan-2-one 
1-hydroxylimonen-2-one +  
1-O-demethyl-6-deoxydoxorubicin 
1-propyl-2-hydroxyacetylpyrrole 
11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 
11,21-dioxoprogesterone 
11-dehydrocorticosterone  
11-deoxycorticosterone +   
11-deoxycorticosterone-21-hemisuccinate 
11-deoxycortisol  
11-oxotestosterone 
11a-hydroxytetracycline 
11alpha-hydroxyprogesterone +  
11alpha-hydroxyprogesterone hemisuccinate +  
11beta,17alpha,21-trihydroxypregnenolone 
11beta-hydroxyandrost-4-ene-3,17-dione 
12-dehydrotetracycline 
12-deoxyphorbol 20-acetate 13-(2-methylbutanoate) 
12-deoxyphorbol-13-(3E,5E-decadienoate) 
12alpha-Methylpregna-4,9(11)-diene-3,20-dione 
15beta-hydroxyprogesterone 
16,17-didehydropregnenolone +  
16,17-didehydropregnenolone 3-beta-D-glucoside 
16,17-didehydroprogesterone 
16-hydroxyphorbol 13-decanoate 12-palmitate 
16alpha,17alpha-dihydroxypregnenolone 
16alpha,17alpha-dihydroxyprogesterone acetophenide +  
16alpha-hydroxyandrost-4-ene-3,17-dione 
16alpha-Hydroxycorticosterone 
16beta-Hydroxy-3,11-dioxopregna-4,17(20)-dien-21-oic acid, gamma-lactone 
16beta-methylpregn-4-ene-3,20-dione 
17,20-dihydroxypregn-4-en-3-one +   
17,21-dihydroxy-5beta-pregnane-3,11,20-trione  
17,21-Epoxy-9-fluoro-11beta-hydroxypregn-4-ene-3,20-dione 
17-epi-17-hydroxyazadiradione 
17-epiestriol +  
17-hydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 
17-hydroxyazadiradione 
17-hydroxypregnenolone 3-sulfate 
17-hydroxyprogesterone 3-O-(carboxymethyl)oxime 
17alpha,21-dihydroxypregnenolone 
17alpha-estradiol +  
17alpha-hydroxy-C21-steroid +   
17alpha-hydroxypregn-5-ene-3,20-dione 
17alpha-hydroxypregnenolone +   
17alpha-hydroxyprogesterone  
17alpha-hydroxywithanolide D 
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  
17beta-Hydroxy-4-methylestr-4-en-3-one 
17beta-hydroxyandrostan-3-one +   
17beta-hydroxyestr-5(10)-en-3-one 
18-hydroxycorticosterone 
19-hydroxyandrost-4-ene-3,17-dione 
19-hydroxydeoxycorticosterone 
19-Norandrostenedione 
19-Norpregna-4,17(20)-dien-3-one 
19-oxotestosterone 
1alpha-hydroxytestosterone 
2,4'-dihydroxyacetophenone 
2,5-dioxo-1-pyrrolidinyl 6-(6-\{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl\}amino)hexanoate 
2-acetyllactic acid +  
2-hydroxyacetophenone 
20beta-dihydrocortisol 
21-acetoxy-11beta,17-dihydroxy-6alpha-methylpregn-4-ene-3,20-dione 
21-dehydrocortisol  
21-dehydrocortisone 
21-deoxycortisol 
21-Hydroxy-5beta-pregnane-3,11,20-trione 
21-hydroxy-C21-steroid 
21-hydroxypregnenolone +  
21-hydroxypregnenolone disulfate 
22-deoxy-20,21-dihydroxyecdysone 
23(S),25-dihydroxy-24-oxovitamin D3 
23,24-dihydrocucurbitacin +  
23,24-dihydrocucurbitacin B 
23,24-dihydrocucurbitacin D 
23,24-dihydrocucurbitacin E 
25-hydroxy-24-oxocalciol 
2beta,21-Dihydroxypregn-4-ene-3,20-dione 
3'-deamino-3'-(3-cyanomorpholin-4-yl)doxorubicin  
3'-deoxysappanone B 
3,6-Dimethoxy-19-norpregna-1,3,5,7,9-pentaen-20-one 
3-(progesterone-4-yl)thiopropionic acid 
3-(progesterone-7alpha-yl)thiopropionic acid 
3-dehydro-4-carboxyzymosterol 
3-dehydroecdysone 
3-farnesyl-3-hydroxy-2-methyl-1-oxo-1lambda(5)-quinolin-4-one 
3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone 
3-hydroxy-3-methyl-2-oxobutanoic acid 
3-hydroxy-3-methyl-2-oxopentanoic acid +  
3-hydroxypregnan-20-one +   
3-hydroxypyruvic acid  
3-oxo Delta(7)-steroid +  
3-oxo-5alpha-steroid +   
3-oxo-5beta-steroid +   
3-oxo-Delta(1) steroid +   
3-oxo-Delta(4) steroid +   
3-oxo-Delta(5)-steroid +   
3a,7b,21-trihydroxy-5b-cholanoic acid 
3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al 
3alpha,12alpha-dihydroxy-5beta-pregnan-20-one diacetate 
3alpha,17alpha,21-Trihydroxy-5beta-pregnan-20-one 
3alpha,20alpha,21-Trihydroxy-5beta-pregnane-11-one 
3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione 
3beta,21-Dihydroxy-4,4,14-trimethyl-5alpha-pregn-8-en-20-one 
3beta-hydroxy-16alpha,17alpha-epoxypregnenolone +  
3beta-hydroxy-16alpha,17alpha-epoxypregnenolone 3-beta-D-glucoside 
3beta-hydroxy-5alpha-pregnan-20-one hemisuccinate 
3beta-hydroxy-5beta-pregnan-20-one hemisuccinate 
4',5'-dihydro-11,5'-dihydroxy-4'-methoxytephrosin 
4'-deoxy-4'-iododoxorubicin 
4'-epidoxorubicin  
4,5-dihydrocortisone +   
A 3-oxo steroid that is cortisone in which the double bond between positions 4 and 5 has been reduced to a single bond.
4,5alpha-dihydrocortisone 
4-amino-4-de(dimethylamino)anhydrotetracycline 
4-de(dimethylamino)-4-oxoanhydrotetracycline 
4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-1-oxide 
4-Methyl-4-aza-5-pregnene-3,20-dione 
4-pregnen-20,21-diol-3-one 
4-pregnen-3beta-ol-20-one 
4-Pregnene-16alpha,21-diol-3,20-dione 
4alpha-methyl-3-oxosteroid +  
4alpha-methyl-5alpha-cholest-8-en-3-one 
4alpha-phorbol 12,13-didecanoate 
5-alpha-THDOC  
5alpha-androst-16-en-3-one 
5alpha-androstane-3beta,17alpha-diol +  
5alpha-cholest-8-en-3-one 
5alpha-Dihydrodeoxycorticosterone 
5alpha-pregnane-3,20-dione  
5beta-dihydroaldosterone 
5beta-dihydrocorticosterone 
5beta-dihydrocortisol 
5beta-dihydrodeoxycorticosterone 
5beta-dihydroepitestosterone 
5beta-pregn-11-ene-3,20-dione 
5beta-pregnane-3,20-dione 
6-(6-\{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl\}amino)hexanoic acid 
6-\{3-[(progesterone-4-yl)thiopropionyl]amino\}hexanoic acid 
6-methylprednisolone +   
6alpha-fluoro-17-hydroxycorticosterone 21-acetate 
6alpha-Hydroxycortisol 
6alpha-methylprednisolone +   
6beta,16alpha,17alpha-trihydroxyprogesterone 
6beta-hydroxycortisol  
6beta-hydroxycortisone 
6beta-hydroxyprogesterone +  
6beta-hydroxyprogesterone hemisuccinate 
7alpha,12alpha,26-trihydroxycholest-4-en-3-one 
7alpha-hydroxypregnenolone 
8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)tetracenomycin C 
8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)tetracenomycin C 
8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C 
8-demethyl-8-(alpha-L-rhamnosyl)tetracenomycin C 
8-demethyltetracenomycin C 
9,11alpha-epoxypregn-4-ene-3,20-dione 
9-fluoro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 
9-fluoro-11beta,17,21-trihydroxy-2alpha-methylpregn-4-ene-3,20-dione 21-acetate 
9-Fluoro-11beta,21-dihydroxy-16alpha,17-(isopropylidenedioxy)pregn-4-ene-3,20-dione 
9-Fluoro-11beta-hydroxypregna-4,16-diene-3,20-dione 
9-fluoro-2alpha-methylpregn-4-ene-3,11,20-trione 
9-Fluoroprednisolone 
9alpha-Fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregn-4-ene-3,20-dione 
9alpha-Fluoro-11beta,17alpha,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 
A-norpregn-3(5)-ene-2,20-dione 
adrenosterone  
alclometasone 
alclometasone dipropionate  
aldosterone +   
aldosterone hemiacetal 
algestone +  
algestone acetonide 
amcinonide 
AMG-925 
andrastin D +  
androstane-3,17-dione +   
anhydrotetracycline +  
anhydrotetracycline zwitterion 
asperfuranone 
avilamycin A 
avilamycin A precursor 
azanigerone E 
beclomethasone +   
beclomethasone dipropionate 
berkeleydione 
berkeleyone A 
berkeleyone B 
berkeleyone C 
berkeleytrione 
betamethasone +   
betamethasone acetate 
betamethasone acibutate 
betamethasone benzoate 
betamethasone dipropionate +   
betamethasone phosphate 
betamethasone sodium phosphate 
betamethasone valerate  
blebbistatin +   
BMS-192548 
bruceolline M 
budesonide  
calotropone 
campest-4-en-3-one 
caribenol B 
carminomycin +  
caudatin-3-O-beta-cymaropyranoside 
chermesinone A 
chloroprednisone 
chlortetracycline  
clobetasol +   
clobetasol propionate 
clocortolone +  
clocortolone pivalate 
clomocycline 
cloprednol 
comazaphilone D 
comazaphilone E 
comazaphilone F 
convallasaponin A 
cortancyl 
cortexolone 
corticosterone +   
cortisol +   
cortisol 17-butyrate 
cortisol 17-valerate 
cortisol 21-acetate 
cortisol 21-sulfate 
cortisol phosphate 
cortisone +   
cortistatin D 
Cortol 
Cortolone 
cucurbitacin B +   
cucurbitacin D 
cucurbitacin E +   
cucurbitacin E 2-O-beta-D-glucopyranoside 
cucurbitacin I +   
cucurbitacin I 2-O-beta-D-glucopyranoside 
cucurbitacin J +  
cucurbitacin J 2-O-beta-D-glucopyranoside 
cucurbitacin K 2-O-beta-D-glucopyranoside 
Cucurbitacin S 
curamycin A 
cyasterone 
cyproterone +   
cyproterone acetate  
cytochalasin D  
dafachronic acids +  
danielone 
daphnetoxin 
Delta(1)-progesterone +   
demegestone 
deoxycortisol +   
desmethylanhydrotetracycline 
desonide 
desoximetasone  
dexamethasone +   
dexamethasone phosphate  
dexamethasone valerate 
dexonorgestrel 
diflorasone +   
diflorasone diacetate 
diflucortolone 
dihydroxyacetone +   
dihydroxyacetone phosphate  
doxorubicin +   
dTDP-4-dehydro-3-methyl-2,6-dideoxy-beta-L-glucose 
dydrogesterone  
elloramycin A 
epi-isochromophilone II 
epitestosterone +   
epitestosterone 17-O-(beta-D-glucuronide) 
erythrulose +  
Euphorbia diterpenoid 3 
finasteride  
floribundasaponin A 
fluclorolone 
fluclorolone acetonide 
fludrocortisone +   
fludrocortisone acetate 
flumethasone +   
flumethasone pivalate 
flunisolide  
fluocinolone acetonide  
fluocortolone 
fluorometholone +   
fluorometholone acetate 
fluperolone 
fluprednidene 
Flurandrenolide  
fluticasone +   
forskolin +   
fruticoside A 
glycerone sulfate 
guignardone N 
halometasone 
harziphilone 
humulone 
hydrocortamate +  
hydrocortisone caproate 
hydrocortisone succinate  
hydroxyacetone +  
hydroxypregnenolone +   
hydroxypyruvaldehyde 
isariotin F 
kidjoranin-3-O-alpha-diginopyranosyl-(1->4)-beta-cymaropyranoside 
kidjoranin-3-O-beta-digitoxopyranoside 
leucosesterlactone 
leucosesterterpenone 
longirostrerone B 
loteprednol +   
LSM-1835 
LSM-5687 
lymecycline 
mannioside A 
medroxyprogesterone +   
medroxyprogesterone acetate  
megestrol +   
meprednisone  
methacycline 
methyl prednisolone-16-carboxylate +  
methyl prednisolone-16alpha-carboxylate 
methylprednisolone acetate 
microdiplodiasol 
minocycline +   
mometasone +   
mometasone furoate  
myrothenone A 
nemorubicin  
neurolenin A 
neurolenin B 
neurolenin C 
neurolenin D 
O-alkylglycerone +  
ochracenomicin A 
Osaterone acetate 
otophylloside B 
oxandrolone  
pennogenin +  
pentanoic acid [11-hydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester 
phorbol +   
phorbol 12,13-dibutanoate  
phorbol 13-acetate 12-myristate  
phorbol 13-butanoate 
phorbol 13-decanoate 12-tiglate 
pipacycline 
polyketomycin 
polypodine B 
poststerone 
preaustinoid A 
preaustinoid A1 
prednisolone +   
prednisolone phosphate 
prednisolone-16-carboxylic acid +  
prednisolone-16alpha-carboxylic acid +  
prednisone +   
prednival 
prednylidene  
pregn-5-ene-3,20-dione 
Pregna-4,11-diene-3,20-dione 
Pregna-4,16-diene-3,11,20-trione 
pregna-4,9(11)-diene-3,20-dione 
pregnan-21-ol 
pregnenolone +   
pregnenolone 3-beta-D-glucoside 
progesterone +   
progesterone 3-O-(carboxymethyl)oxime +  
promegestone  
pterolinus I 
purpurquinone A 
purpurquinone B 
purpurquinone C 
rimexolone  
robustaside E 
rolitetracycline 
RU 5135  
sapintoxin D 
TAN-1612 
testosterone 17-glucosiduronic acid  
tetracenomycin C +  
tetracenomycin X 
tetracycline +   
Tetrahydrocorticosterone 
tetrahydrocortisol 
tigecycline +   
tinyatoxin 
tixocortol +  
tixocortol pivalate 
triamcinolone +   
triamcinolone acetonide  
trichanolide 
trigoheterin E, (rel)- +  
trimegestone  
tubocapsanolide F 
ulipristal acetate 
Urocortisone 
viridicatumtoxin 
zhankuic acid A +  
zhankuic acid A methyl ester 
zhankuic acid B 
zhankuic acid C 
zymosterol intermediate 2 

Synonyms
Related Synonyms: Formula=C21H30O5 ;   InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12,14-15,18,22,26H,3-11H2,1-2H3/t12?,14-,15-,18+,19-,20-,21-/m0/s1 ;   InChIKey=YCLWEYIBFOLMEM-AGIMVQGUSA-N ;   SMILES=[H][C@@]12CCC3CC(=O)CC[C@]3(C)[C@@]1([H])C(=O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO ;   dihydrocortisone
Xrefs: Beilstein:4206949 "Beilstein" ;   Reaxys:4206949 "Reaxys"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.