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Term:
N-methyl-D-aspartic acid (CHEBI:31882)
Annotations: Rat: (3) Mouse: (3) Human: (3) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
(+)-minovincinine 
(-)-demecolcine  
(-)-minovincinine 
(-)-vincadifformine 
(12R)-hydroxy-10,11-dihydroleukotriene E4 
(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylic acid 
(1R,5aS,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylic acid 
(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin  
(1S,2S)-2-[(1S)-1-amino-1-carboxyethyl]-1-cyclopropanecarboxylic acid 
(2R*,6S*)-2,6-diamino-3xi-hydroxyheptanedioic acid 
(2R,3S,2'R)-nadolol +   
(2R,3S,2'S)-nadolol +   
(2S)-2-[(R)-1-carboxyethylamino]pentanoic acid 
(2S,3R,2'R)-nadolol +   
(2S,3R,2'S)-nadolol +   
(2Z,4E)-4-amino-6-oxohepta-2,4-dienedioic acid 
(3R)-3-methyl-D-ornithine 
(3R,5R)-5-amino-3-methyl-D-proline 
(5aS)-5,5a-dihydrophenazine-1,6-dicarboxylic acid 
(R)-DRF053 +  
(R)-tetrahydropapaverine +  
(S)-(+)-4-(5-carboxypentyl)methamphetamine 
(S)-2-methylamino-1-phenylpropan-1-one 
(S,S)-2,5-di-(p-hydroxybenzyl)piperazine 
(Z)-6-amino-2-hydroxy-4-(2-oxovinyl)hept-3-enedioic acid 
1-(1,3-benzodioxol-5-yl)-N-ethylpropan-2-amine +   
1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid +  
1-(2-chlorophenyl)-2-isopropylaminoethanol +   
1-(4-methoxyphenyl)-2-\{[4-(4-nitrophenyl)butan-2-yl]amino\}ethanol 
1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate +   
1-[4-carboxy-2-(3-pentylamino)phenyl]-5,5-bis(hydroxymethyl)pyrrolidin-2-one 
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol +   
10-hydroxycoronaridine 
17-O-acetylnorajmaline 
19-O-acetylhoerhammericine 
2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol] +   
2,2'-iminodipropanoic acid +  
2,3,4,5-tetrahydrodipicolinic acid +  
2,3,8,9-tetramethoxy-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene +  
2,5-bis(2-hydroxyethylamino)-3,6-diaziridinylbenzoquinone 
2,6-diaminopimelic acid +  
2,6-dihydroxypseudooxynicotine 
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl]amino\}-2-(propan-2-yl)pentanenitrile +   
2-(6-aminohexylamino)-cAMP 
2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazolin-4-amine 
2-(hydroxymethyl)-4-(1-hydroxy-2-\{[6-(4-phenylbutoxy)hexyl]amino\}ethyl)phenol +  
2-\{[2-(2-chlorophenyl)-2-hydroxyethyl]amino\}-N-[(2-fluorophenyl)methyl]acetamide 
2-amino-3-(3-oxoprop-1-enyl)but-2-enedioic acid +  
2-amino-3-oxoadipic acid 
2-aminoadipic acid +  
2-aminopimelic acid +  
2-benzylidene-3-(cyclohexylamino)indan-1-one +  
2-S-cysteinyl-DOPA 
20-hydroxy-leukotriene E4 
20-oxoleukotriene E4 
3'-hydroxy-4'-methoxydiclofenac 
3'-hydroxydiclofenac 
3-(methylaminomethyl)indole 
3-(phenethylamino)-butan-2-one 
3-(phenethylamino)-butan-2-one(1+) 
3-[(3-aminopropyl)amino]-4-hydroxybenzoic acid 
3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonic acid  
3-[(4-bromophenyl)amino]-3-(4-methoxyphenyl)-1-phenylpropan-1-one 
3-\{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl\}propanoic acid +   
3-aminoadipic acid +  
3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[3-(pyridin-4-yl)benzyl]-1-benzothiophene-2-carboxamide 
3-epi-fagomine 
3-fluoro-D-tyrosine 
3-hydroxy-D-aspartic acid +  
3-hydroxy-L-glutamic acid +  
3-hydroxyaspartic acid +  
3-methylthioaspartic acid +  
3-nitro-D-tyrosine 
3-thio-L-aspartic acid +  
4',5-dihydroxydiclofenac 
4'-hydroxydiclofenac  
4'-O-methylnorbelladine 
4-(1-hydroxy-2-\{[4-(4-hydroxyphenyl)butan-2-yl]amino\}ethyl)phenol +   
4-(6-ethoxypyrazolo[1,5-b]pyridazin-3-yl)-N-(3-methoxyphenyl)pyrimidin-2-amine 
4-(6-ethoxypyrazolo[1,5-b]pyridazin-3-yl)-N-[3-(morpholin-4-yl)phenyl]pyrimidin-2-amine 
4-(L-gamma-glutamylamino)butanoic acid 
4-(methylamino)antipyrine 
4-\{2-[(2-hydroxybenzyl)amino]ethyl\}-2,5-dimethoxybenzonitrile 
4-chloro-6-\{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl\}benzene-1,3-diol 
4-hydroxy-4-methylglutamate 
4-hydroxy-4-methylglutamic acid 
4-hydroxy-L-glutamic acid +  
4-hydroxymethamphetamine 
4-methyl-L-glutamic acid 
4-methyl-N-[3-(morpholin-4-yl)phenyl]-3-[3-(piperidin-4-yl)-1,2-benzoxazol-6-yl]benzamide 
4-methylene-D-glutamic acid 
5,10-dihydrophenazine-1,6-dicarboxylic acid 
5,5,7,12,12,14-hexamethyl-1,4,8,11-tetrazacyclotetradecane 
5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl hydrogen sulfate 
5-(2-\{[2-(2-ethoxyphenoxy)ethyl]amino\}propyl)-2-methoxybenzenesulfonamide +   
5-(methylamino)-2-phenyl-4-[3-(trifluoromethyl)phenyl]furan-3(2H)-one +  
5-[(1-phenylcyclohexyl)amino]pentanoic acid 
5-[1-hydroxy-2-(isopropanylamino)ethyl]benzene-1,3-diol +   
5-adenylyl-2-aminoadipic acid 
5-amino-1-anilinoimidazole-4-carbonitrile 
5-chloro-N-\{1-[4-(difluoromethoxy)phenyl]propyl\}-6-methylpyrimidin-4-amine +  
5-hydroxy-D-tryptophan 
5-hydroxydiclofenac  
6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline +  
6-chloro-D-tryptophan 
6-hydroxypseudooxynicotine 
7-chloro-D-tryptophan 
7-nitrobenzoxadiazole-6-aminohexanoic acid 
8-(6-aminohexylamino)-cAMP 
8-demethyl-8-(methylamino)riboflavin 
9-cyclopentyl-N(8)-(2-fluorophenyl)-N(2)-(4-methoxyphenyl)-9H-purine-2,8-diamine 
\{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl\}methanol +  
abediterol 
acamprosate  
acebutolol  
aceclofenac  
acridine half-mustard 
acridine red 3B free base 
actinodaphnine 
adrenergic agent +   
alangimarckine 
albuterol +   
alminoprofen 
alpha-(methylamino)isobutyric acid  
alpha-putrescinylthymine 
alprenolol +   
alvespimycin 
ambenonium chloride  
AMG-925 
amineptine +  
aminomalonic acid  
amocarzine 
amodiaquine +   
amoscanate 
angiotensin I 
anilazine 
argatroban 
AS1842856 
atenolol acid 
atomoxetine +   
baeocystin 
BCI-215 
BDA-366 
benzonatate 
Benzylhydrochlorothiazide 
beta-(2-thienyl)-D-alanine 
beta-alanopine +  
betahistine  
binimetinib 
bis(7)-tacrine 
bitolterol +  
bupirimate  
bupropion +   
cadabicine sulfate 
caldopentamine 
cangrelor  
carvedilol  
CBL0137 
CD532 
ceratamine A 
ceritinib  
CGP 12177  
CGP 78608 
chanoclavine-I +  
chanoclavine-I aldehyde 
CHIR 99021  
chlordiazepoxide +   
chloroquine +   
cholinergic drug +   
chrysopine +  
CHZ868 
cinacalcet +   
clenbuterol +   
cobimetinib  
coelenterazine dioxetanone 
coelenterazine h dioxetanone 
colterol 
cyclopentamine 
cyprodinil  
cytisine  
CZC-25146 
D-2-aminopentanoic acid 
D-4-dihydroxyphenylglycine 
D-alanine +  
D-alloisoleucine +  
D-alpha-amino acid residue +  
D-alpha-aminobutyric acid +  
D-arginine +  
D-asparagine +  
D-aspartic 1-amide 
D-aspartic acid +   
D-cysteine +  
D-glutamic acid +  
D-glutamine +  
D-histidine +  
D-homoserine +  
D-isoleucine +  
D-kynurenine 
D-leucine +  
D-lysine +  
D-methionine +  
D-nopaline 
D-octopine 
D-ornithine +  
D-phenylalanine +   
D-proline +  
D-selenocysteine +  
D-serine +  
D-thioproline 
D-threonine +  
D-tryptophan +  
D-tyrosine +  
D-valine +  
D617 
dacomitinib  
dasatinib (anhydrous) +  
desipramine +   
desmethyldoxepin +  
desmethylranitidine 
diclofenac +   
diclofenac beta-D-glucosiduronic acid 
diisopropanolamine 
dinoflagellate luciferin 
diphenylamine +   
dopaminergic agent +   
Durazol blue 4R (acid form) 
dysidine 
E3040 +   
E3040 glucuronide 
enasidenib 
ergometrine +  
erlotinib +   
ethirimol 
ethyl 2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate +  
ethylenediaminediacetic acid 
excitatory amino acid agonist +   
ezogabine  
fenamic acid  
fenfluramine +   
fenoterol +   
finafloxacin 
florbetaben ((18)F) 
fluazinam  
flutemetamol ((18)F) 
G-573 
GABA agent +   
GABA reuptake inhibitor +   
gamma-D-glutamyl-meso-diaminopimelic acid 
gefitinib +   
GGTI-2133 free base 
GHB receptor agonist +   
gilteritinib 
glafenine  
GSK3-XIII 
guvacine +  
guvacoline 
HG-10-102-01 
HG-9-91-01 
histaminergic drug +   
hoerhammericine +  
Hoffman's violet free base 
hydroxychloroquine  
ICI 118551  
idelalisib  
imidapril +   
imidaprilat  
iminoctadine +  
iminodiacetic acid +  
iminodiacetonitrile 
indacaterol 
indolmycin 
iodocyanopindolol  
iproheptine 
Iproheptine hydrochloride 
isometheptene 
isoprenaline  
ketamine +   
L-3-aminosuccinimide 
L-BMAA 
labetalol  
LDC4297 
leukotriene E3 +  
leukotriene E4 +   
LRRK2-IN-1 
LSM-12459 
lumiracoxib  
mannopine 
meclofenamic acid  
mefenamic acid  
melagatran +   
mepanipyrim  
mephedrone  
metachromin S 
methyl 3-\{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl\}propanoate +   
methyl 5-(hydroxymethyl)pyrrolidine-2-carboxylate 
methyl 5-(hydroxymethyl)pyrrolidine-3-carboxylate 
methyl blue free acid 
methyl gamma-D-aspartate 
methyl N-(2,6-dichlorobenzyl)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]alaninate 
methyl N-methylanthranilate 
metipranolol  
metoprolol  
miotic +   
ML228 
ML240 
momelotinib 
monomethylphosphatidylethanolamine 36:2 
N(1),N(12)-diethylspermine  
N(1),N(8)-bis(coumaroyl)spermidine 
N(1),N(8)-bis(sinapoyl)-spermidine 
N(1),N(8)-bis-(dihydrocaffeoyl)spermidine 
N(2)-(2-carboxyethyl)-L-arginine 
N(2)-[3-methoxy-4-(morpholin-4-yl)phenyl]-N(4)-(quinolin-3-yl)pyrimidine-2,4-diamine 
N(2)-methylguanine 
N(4)-\{2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl\}pentane-1,4-diamine +  
N(6)-(6-aminohexyl)-cAMP 
N(6)-[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]-D-lysine 
N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine] 
N,N'-bis[3-(ethylamino)propyl]-2-butene-1,4-diamine 
N,N'-diphenyl-1,4-phenylenediamine  
N,O-didesmethylvenlafaxine 
N,O-dimethyltyramine +   
N-(1-benzylpiperidin-4-yl)-2-(pyridin-3-yl)quinazolin-4-amine 
N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine +  
N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine 
N-(2,6-dimethylindan-1-yl)-6-(1-fluoroethyl)-1,3,5-triazine-2,4-diamine +  
N-(2-[(2-aminoethyl)(methyl)amino]-5-\{[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino\}phenyl)acetamide 
N-(2-aminoethyl)-1-aziridine-ethanamine 
N-(2-hydroxyethyl)-beta-alanine 
N-(2-hydroxyethyl)iminodiacetic acid 
N-(2-methoxyethyl)-4-\{[6-(pyridin-4-yl)quinazolin-2-yl]amino\}benzamide 
N-(3-\{[2-(2-fluorophenyl)quinazolin-4-yl]amino\}phenyl)acetamide 
N-(3-fluorophenyl)-2-(pyridin-4-yl)quinazolin-4-amine 
N-(3-methoxyphenyl)quinazolin-4-amine 
N-(4-methylphenyl)-2-(pyridin-4-yl)quinazolin-4-amine 
N-(4-nitrophenyl)-3-oxovalidamine 
N-(5'-phosphopyridoxyl)-D-alanine 
N-(phosphonomethyl)iminodiacetic acid 
N-[1-(3,5-dimethylphenoxy)propan-2-yl]-6-(2-fluoropropan-2-yl)-1,3,5-triazine-2,4-diamine +  
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  
N-[2-hydroxy-5-(1-hydroxy-2-\{[1-(4-methoxyphenyl)propan-2-yl]amino\}ethyl)phenyl]formamide +  
N-[cyano(2-thienyl)methyl]-4-ethyl-2-(ethylamino)-1,3-thiazole-5-carboxamide +  
N-\{2'-[(4-fluorophenyl)amino]-4,4'-bipyridin-2-yl\}-4-methoxycyclohexanecarboxamide 
N-\{3-[(2-phenylquinazolin-4-yl)amino]phenyl\}acetamide 
N-\{4-[2-ethyl-1-(1,2,4-triazol-1-yl)butyl]phenyl\}-1,3-benzothiazol-2-amine +  
N-acetyl-LL-2,6-diaminopimelic acid 
N-acyl-D-aspartic acid 
N-benzylquinazolin-4-amine 
N-cyclopropyl-3-\{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydropyrazolo[3,4-b]pyridin-4-yl]amino\}-4-methylbenzamide 
N-deethylaconine 
N-desmethylvenlafaxine 
N-ethyl-N'-[4-[4-[4-[4-[4-[4-[4-[4-(ethylamino)butylamino]butylamino]butylamino]butylamino]but-2-enylamino]butylamino]butylamino]butyl]butane-1,4-diamine 
N-ethylasparagine +  
N-formyl-D-kynurenine 
N-methyl-1-(5-pyridin-3-ylfuran-2-yl)methanamine 
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine +   
N-methyl-beta-alanine +  
N-methyl-D-aspartic acid  
An aspartic acid derivative having an N-methyl substituent and D-configuration.
N-methylglucamine +   
N-methylleucine 
N-oxalylglycine +  
N-pyrazin-2-yl-N(2)-\{1-[2-(1H-pyrazol-1-yl)phenyl]ethyl\}glycinamide 
nerve growth factor stimulator +  
neurotransmitter transporter modulator +   
nilotinib  
nisoxetine  
nocardicin A 
nocardicin C 
nocardicin G 
norajmaline +  
norbelladine +  
norflurazon  
noribogaine 
NSC 23766 +   
O(4)-phospho-D-tyrosine 
O-succinyl-L-serine 
O-ureido-D-serine 
octamylamine 
olodaterol  
onosmin A +  
onosmin B 
opioid agent +   
osimertinib  
oxidized dinoflagellate luciferin 
p-aminodiphenylamine +   
p-N,N-bis(2-chloroethyl)amino-D-phenylalanine 
PA-16-0081C 
pacein 
palbociclib  
pamapimod 
panobinostat  
PD 0325901  
PD-153035 
PD158780 
pendimethalin  
pevonedistat  
pexidartinib 
PFE-PKIS 18 
phenylephrine  
pibutidine 
plerixafor 
practolol  
pradimicin +  
praliciguat 
propafenone  
propylhexedrine 
pseudoephedrine 
purmorphamine  
pyrimethanil  
pyriminostrobin 
R24 
retaspimycin 
reversine 
robenacoxib 
rucaparib  
sapitinib 
sarpagine +  
SB 415286  
SCH51344 
Se-methyl-D-selenocysteine +  
secodine 
secondary amine +   
selumetinib  
serotonergic drug +   
sertraline  
SMER 28 
solabegron  
sotalol  
spectinomycin 
spirapril  
spiraprilat +   
spirit blue base 
Src Inhibitor-1 
Src Inhibitor-5 
stepharine 
strychnine +   
strychnine hydrochloride 
succinyladenosine 
tanespimycin  
tauropine 
terpendole J 
TG101209 
thalicpureine 
threo-3-methyl-L-aspartic acid 
THZ531 
ticagrelor  
TMC-52A 
TMC-52B 
TMC-52C 
TMC-52D 
tolfenamic acid  
torasemide  
trandolapril  
trandolaprilat 
Trientine hydrochloride 
tubulosine 
validamycin A 
validamycin B 
validoxylamine A 
validoxylamine A 7'-phosphate 
validoxylamine B 
varenicline  
vatalanib +   
vilanterol +  
WAY-316606 
ximelagatran  
xylazine  
zinolol 
ZM 323881 
ZM447439 

Synonyms
Related Synonyms: (R)-2-Methylamino-succinic acid ;   2-Methylamino-succinic acid ;   Formula=C5H9NO4 ;   InChI=1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1 ;   InChIKey=HOKKHZGPKSLGJE-GSVOUGTGSA-N ;   Methyl aspartic acid ;   N-Methyl aspartic acid ;   N-Methyl-D-aspartate ;   N-Methylaspartate ;   NMDA ;   SMILES=CN[C@H](CC(O)=O)C(O)=O
Alternate IDs: CHEBI:164776
Xrefs: Beilstein:1724431 ;   CAS:6384-92-5 ;   HMDB:HMDB0002393 ;   KEGG:C12269
Xref Mesh: MESH:D016202
Xrefs: MetaCyc:CPD-10705 ;   PDBeChem:OEM ;   PMID:10514280 ;   PMID:10893301 ;   PMID:1967316 ;   PMID:2170646 ;   PMID:3351864 ;   PMID:8568805 ;   PMID:9572889 ;   Reaxys:1724431 ;   Wikipedia:N-Methyl-D-aspartic_acid

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.