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(-)-beta-caryophyllene 
(2S)-2-(4-\{[(1R,2S)-2-hydroxycyclopentyl]methyl\}phenyl)propanoic acid 
(E)-3-tosylacrylonitrile 
(S)-etodolac 
(S)-ketorolac +   
1-[1-[(2-chloro-6-fluorophenyl)methyl]-2-oxo-3-pyridinyl]-3-(phenylmethyl)urea 
1-[1-[(4-fluorophenyl)methyl]-5-methyl-2-oxo-3-pyridinyl]-3-(phenylmethyl)urea 
3,5,6-trichloropyridine-2-one  
3,6-dichloropyridine-2,5-dione 
3,6-dihydroxypyridine-2,5-dione 
3-cyano-4-phenyl-6-(3-bromo-6-hydroxyphenyl)-2-pyridone 
4-(3,5-dimethylphenoxy)-5-\{[(furan-2-ylmethyl)sulfanyl]methyl\}-3-iodo-6-methylpyridin-2(1H)-one 
4-(methylamino)antipyrine 
4-aminoantipyrine 
4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid 
4-pyridones +   
5-(2'-carboxyethyl)-4,6-dihydroxypicolinic acid 
5-(3'-carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinic acid 
5-(3'-carboxy-3'-oxopropyl)-4,6-dihydroxypicolinic acid 
6-chloro-3-hydroxypyridine-2,5-dione 
[5-fluoro-1-(4-isopropylbenzylidene)-2-methylinden-3-yl]acetic acid 
aceclofenac  
acemetacin  
acetosyringone +  
acetylsalicylic acid +   
acromelic acid A 
adapalene  
alclofenac  
alminoprofen 
almotriptan +   
almotriptan malate 
amantadine  
amantadine sulfate 
amfenac +   
amfenac sodium hydrate 
aminophenazone  
amlexanox  
amodiaquine +   
ampiroxicam 
antipyrine +   
apazone  
apigenin 7-O-beta-D-glucoside  
apigenin 7-O-beta-D-glucoside(1-) 
apocynin  
apremilast 
arasertaconazole +   
aspyridone A 
aspyridone B 
baicalin  
balsalazide +   
balsalazide disodium 
bendazac 
benoxaprofen  
benzydamine  
biphenyl-4-ylacetic acid +  
bromfenac  
bromfenac sodium salt +  
bromfenac sodium salt sesquihydrate 
bufexamac 
bumadizone 
bumadizone calcium +  
bumadizone calcium hemihydrate 
capsaicin  
carbachol  
carbamazepine +   
carprofen +   
celecoxib  
CGP 28014  
chlorprothixene +   
chrysogedone A 
chrysogedone B 
ciclopirox +   
cimicoxib 
clofazimine  
clonidine +   
clonixin 
clonixin lysine salt 
corilagin  
crisaborole 
Delta(9)-tetrahydrocannabinol +   
deracoxib 
dexibuprofen 
dexketoprofen 
dexmedetomidine +   
diclofenac +   
difenpiramide 
diflunisal  
dihydroergotamine +   
dihydroergotamine mesylate 
dihydroergotamine tartrate 
dimethyl sulfoxide +   
dithiosalicylic acid 
droxicam 
eletriptan  
eletriptan hydrobromide 
emarginatine B 
emarginatine F 
enprofylline +  
ergotamine  
eribaxaban 
etodolac +   
etoricoxib  
fenbufen  
fendosal 
fenoprofen  
fenoprofen calcium 
firocoxib 
flufenamate 
flufenamic acid  
flunixin  
flunixin meglumine  
flunoxaprofen 
flurbiprofen +   
friedelin +  
garenoxacin 
glafenine  
huperzine A  
hydroxypyridone antifungal drug +   
ibufenac  
ibuprofen +   
ibuproxam 
ilicicolin H 
indigoidine 
indometacin +   
indoprofen  
isoxicam 
JMV 390-1 
kebuzone 
ketoprofen  
ketorolac  
lamotrigine  
leflunomide  
LLP-3 
lonazolac 
lonazolac calcium 
lornoxicam  
loxoprofen +   
loxoprofen sodium +  
loxoprofen sodium hydrate 
lumiracoxib  
mavacoxib 
meclofenamic acid  
mefenamic acid  
meloxicam  
mesalamine  
metacetamol  
metamizole 
metamizole sodium  
methotrimeprazine 
methoxyflurane  
metiazinic acid 
militarinone A 
milrinone  
miroprofen 
mofebutazone 
N-(2,6-dichlorobenzoyl)-4-[1,6-dimethyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]-L-phenylalanine 
N-methyl-6-pyridone-3-carboxamide +   
nabumetone  
naproxcinod 
naproxen +   
naproxen sodium 
naproxol 
nedocromil  
nefopam  
nefopam hydrochloride 
nepafenac 
nimesulide  
nitroflurbiprofen  
nitrosulindac 
O-methylsalicylic acid +   
oleocanthal 
olsalazine 
olsalazine sodium 
omega-conotoxin MVIIA 
oxametacin 
oxaprozin  
oxyphenbutazone +   
oxyphenbutazone hydrate 
paracetamol +   
parecoxib  
parthenolide +   
perampanel +  
PH 797804 
phenacetin  
phenazopyridine  
phenazopyridine hydrochloride 
phenylbutazone +   
pirfenidone  
A pyridone that is 2-pyridone substituted at positions 1 and 5 by phenyl and methyl groups respectively. An anti-inflammatory drug used for the treatment of idiopathic pulmonary fibrosis.
piroctone +  
piroxicam +   
proglumetacin +  
proglumetacin dimaleate 
propyphenazone 
pyridoxatin 
quinine +   
ricinine 
robenacoxib 
rofecoxib  
rosmarinic acid +   
salicin +   
salicylamide +   
salsalate  
SC560 
sertaconazole  
sertaconazole nitrate 
sodium meclofenamate monohydrate 
solasodine  
solasodine(1+) +  
SPF-32629A 
SPF-32629B 
streptokordin 
sulfamazone 
sulfasalazine  
sulindac +   
sulindac sulfide  
suprofen  
suxibuzone  
tenidap  
tenoxicam  
tepoxalin  
teriflunomide  
tert-butyl N-\{1-[(1S)-1-\{[(1R,2S)-1-(benzylcarbamoyl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl\}-2-cyclopropylethyl]-2-oxopyridin-3-yl\}carbamate 
tetrahydropalmatine  
thiosalicylic acid  
tiaprofenic acid  
tolfenamic acid  
tolmetin  
tolmetin sodium +  
tolmetin sodium dihydrate 
valdecoxib +   
vedaprofen 
willow bark extract 
ximoprofen 
zileuton  
zomepirac  

Synonyms
Exact Synonyms: 5-methyl-1-phenylpyridin-2(1H)-one
Related Synonyms: AMR-69 ;   Esbriet ;   Formula=C12H11NO ;   InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3 ;   InChIKey=ISWRGOKTTBVCFA-UHFFFAOYSA-N ;   SMILES=Cc1ccc(=O)n(c1)-c1ccccc1 ;   pirfenidona ;   pirfenidonum
Xrefs: Beilstein:1526549 ;   CAS:53179-13-8 ;   Drug_Central:4224 ;   KEGG:D01583 ;   LINCS:LSM-4190
Xref Mesh: MESH:C093844
Xrefs: PMID:25432946 ;   PMID:25459156 ;   PMID:25542603 ;   PMID:25593606 ;   PMID:25596380 ;   PMID:25604027 ;   PMID:25624597 ;   PMID:25639750 ;   PMID:25678074 ;   PMID:25691376 ;   PMID:25726556 ;   PMID:25727967 ;   PMID:25738437 ;   Reaxys:1526549 ;   Wikipedia:Pirfenidone

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.