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Ontology Browser

Term:
(2E,4E)-hexa-2,4-dienoic acid (CHEBI:38358)
Annotations: Rat: (5) Mouse: (5) Human: (5) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
(+)-DCA-CL 
(-)-DCA-CL 
(2-trans,6-cis)-dodeca-2,6-dienoic acid +  
(2E)-11-hydroxy-2-dodecenoic acid 
(2E)-11-hydroxyundec-2-enoic acid +  
(2E)-12-hydroxydodec-2-enoic acid +  
(2E)-13-hydroxytridec-2-enoic acid +  
(2E)-14-hydroxytetradec-2-enoic acid +  
(2E)-15-hydroxypentadec-2-enoic acid +  
(2E)-16-hydroxyhexadec-2-enoic acid +  
(2E)-17-hydroxyheptadec-2-enoic acid +  
(2E)-18-hydroxyoctadec-2-enoic acid +  
(2E)-19-hydroxynonadec-2-enoic acid +  
(2E)-2-heptadecenoic acid +  
(2E)-20-hydroxyicos-2-enoic acid +  
(2E)-21-hydroxyhenicos-2-enoic acid +  
(2E)-3-methylhex-2-enoic acid 
(2E)-7-hydroxyhept-2-enoic acid +  
(2E)-9-hydroxynon-2-enoic acid +  
(2E,10R)-10-hydroxyundec-2-enoic acid +  
(2E,11R)-11-hydroxydodec-2-enoic acid +  
(2E,12R)-12-hydroxytridec-2-enoic acid +  
(2E,13R)-13-hydroxytetradec-2-enoic acid +  
(2E,14R)-14-hydroxypentadec-2-enoic acid +  
(2E,15R)-15-hydroxyhexadec-2-enoic acid +  
(2E,16R)-16-hydroxyheptadec-2-enoic acid +  
(2E,17R)-17-hydroxyoctadec-2-enoic acid +  
(2E,18R)-18-hydroxynonadec-2-enoic acid +  
(2E,19R)-19-hydroxyicos-2-enoic acid +  
(2E,20R)-20-hydroxyhenicos-2-enoic acid +  
(2E,24R)-24-[(alpha-L-ascarosyl)oxy]-2-methylpentacos-2-enoic acid 
(2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid 
(2E,4E)-hexa-2,4-dienoic acid +   
A sorbic acid having trans-double bonds at positions 2 and 4; a food preservative that can induce cutaneous vasodilation and stinging upon topical application to humans. It is the most thermodynamically stable of the four possible geometric isomers possible, as well as the one with the highest antimicrobial activity.
(2E,4E,6R,8Z)-6-hydroxytetradeca-2,4,8-trienoic acid 
(2E,4Z)-2-hydroxy-7-methyl-6-oxo-2,4-octadienoic acid 
(2E,4Z)-6-(4-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid 
(2E,4Z)-8-hydroxydeca-2,4-dienoic acid +  
(2E,4Z)-hexa-2,4-dienoic acid 
(2E,6E,10E)-geranylgeranic acid +  
(2E,6E,10E,14E)-omega-hydroxygeranylgeranic acid 
(2E,6E,10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoic acid 
(2E,6R)-6-hydroxyhept-2-enoic acid +  
(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoic acid +  
(2E,7R)-7-hydroxyoct-2-enoic acid +  
(2E,8R)-8-hydroxynon-2-enoic acid +  
(2E,9R)-9-hydroxydec-2-enoic acid +  
(2S,3R)-glycosmisic acid 
(2Z)-2,3-dihydroxyacrylic acid 
(2Z,4E)-4-hydroxymuconic semialdehyde 
(2Z,4E)-hexa-2,4-dienoic acid 
(2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid 
(2Z,4Z)-hexa-2,4-dienoic acid 
(3R)-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylic acid 
(3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carboxylic acid 
(E)-10-hydroxydec-2-enoic acid +   
(E)-11-methyldodec-2-enoic acid 
(E)-2,4,6-trimethyltetracos-2-enoic acid 
(E)-3-(indol-2-yl)acrylic acid 
(E)-3-(indol-3-yl)acrylic acid 
(E)-endo-beta-bergamoten-12-oic acid 
(E)-hexadec-2-enoic acid +  
(E)-non-2-enoic acid 
(E,E)-piperic acid +   
(Z)-13-methyltetradec-2-enoic acid 
(Z)-14-methylpentadec-2-enoic acid 
(Z)-3-amino-2-methylacrylic acid +  
(Z)-3-aminoacrylic acid 
(Z)-tetradec-2-enoic acid 
1'-deoxyabscisic acid 
1,4,5,6-tetrahydro-6-oxonicotinic acid 
1-carbapenem-3-carboxylic acid 
1-deoxy-11-oxopentalenic acid 
1-deoxypentalenic acid 
14-hydroxy-6,12-muuroloadien-15-oic acid 
2,3-dihydroxy-2,3-dihydrobenzoic acid +  
2,4-dihydroxy-5-methyl-6-oxo-2,4-hexadienoic acid 
2,6-dimethyl-5-methylenehept-2-enoic acid +  
2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronic acid)-6-O-sulfo-D-galactopyranose +  
2-amino-5-chloro-cis,cis-muconic 6-semialdehyde 
2-aminoacrylic acid +  
2-aminomuconic 6-semialdehyde 
2-butenoic acid +   
2-chloroacrylic acid 
2-decenoic acid +  
2-dodecenoic acid +  
2-ethylacrylic acid 
2-heptenoic acid +  
2-hexacosenoic acid +  
2-hydroxy-3-methyl-2-butenoic acid 
2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid 
2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid 
2-hydroxy-5-methyl-cis,cis-muconic semialdehyde 
2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid 
2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid 
2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate 
2-hydroxy-6-oxo-2,4-heptadienoic acid +  
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid 
2-hydroxy-6-oxohexa-2,4-dienoic acid +  
2-hydroxyacrylic acid 
2-hydroxypenta-2,4-dienoic acid +  
2-methylbut-2-enoic acid +  
2-tetradecenoic acid +  
2-trans-4'-dihydroabscisic acid 
2-undecenoic acid +  
3,4,5-trihydroxy-1-cyclohexene-1-carboxylic acid 
3,7-dimethylocta-2,6-dienoate(1-) 
3-(4,6-dihydroxy-3-oxocyclohexa-1,4-dien-1-yl)acrylic acid 
3-dehydroshikimic acid 
3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oic acid +  
3-hydroxybut-2-enoic acid +   
3-methylbut-2-enoic acid +  
3-nitroacrylic acid 
3alpha,7beta-dihydroxy-5beta-cholest-24-en-26-oic acid 
4,4'-diapolycopen-4-oic acid 
4,4'-diaponeurosporenoic acid 
4-coumaroylshikimic acid 
4-deoxy-Delta(4)-beta-D-GlcpA 
5-[(E)-caffeoyl]shikimic acid 
5-aminocyclohexa-1,3-diene-1-carboxylic acid +  
6-imino-5-oxocyclohexa-1,3-dienecarboxylic acid 
6:2 fluorotelomer unsaturated carboxylic acid 
6beta,16beta-diacetoxy-25-hydroxy-3,7-dioxy-29-nordammara-1,17(20)-dien-21-oic acid 
7-deoxyloganetic acid +  
7-deoxyloganic acid 
7beta-aminocephalosporanic acid  
8,8a-epoxymorellic acid 
8:2 fluorotelomer unsaturated carboxylic acid 
8alpha,19-dihydroxylabd-13E-ene-15-oic acid 
abscisic acids +   
acrivastine  
acrylic acid +   
all-trans-7-hydroxyhexadeca-2,4,8,10-tetraenoic acid +  
all-trans-acitretin  
alpha-bergamotenoic acid 
alpha-santalenoic acid 
ascr#13 
ascr#15 +  
ascr#17 +  
ascr#19 +  
ascr#21 +  
ascr#23 
ascr#25 
ascr#29 
ascr#3 +  
ascr#31 
ascr#33 
ascr#35 
ascr#37 
ascr#7 +  
beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-D-GlcpNAc +  
caffeic acid quinone 
carbapenem MM22383 
cinnamic acids +   
cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylic acid 
cuevaene A 
Cyclohex-1-enecarboxylic acid 
cyclohexa-1,5-diene-1-carboxylic acid +  
cyclosporin A metabolite M1A 
dihydrophaseic acid 
dodeca-2,6,10-trienoic acid +   
enbucrilate 
enol-phenylpyruvic acid 
epi-dihydrophaseic acid 
ethyl sorbate 
farnesoic acid +   
fusidic acid  
gamendazole 
gaudichaudiic acid F 
gaudichaudiic acid G 
geranic acid  
glycosmisic acid +  
glycosmisic acid 4'-sulfate 
glycosmisic acid sulfate 
guvacine +  
hbas#3 
hepta-2,4,6-trienoic acid +  
hygrolidin 
icas#15 
icas#17 
icas#19 
icas#21 
icas#3 
icas#7 
icos#15 
icos#17 
icos#3 
kalimantacin B 
leptomycin +   
loganic acid 
maleamic acid 
mbas#3 
meropenem +   
methacrylic acid +   
myrtenic acid 
N-formylmaleamic acid 
octadec-2-enoic acid +  
oscr#15 +  
oscr#17 +  
oscr#19 +  
oscr#21 +  
oscr#23 +  
oscr#25 +  
oscr#27 +  
oscr#29 +  
oscr#3 +  
oscr#31 +  
oscr#33 +  
oscr#35 +  
oscr#37 +  
oscr#7 +  
pent-2-enoic acid +  
penta-2,4-dienoic acid +   
pentalenolactone 
pentalenolactone D 
pentalenolactone E 
pentalenolactone F 
perillic acid +   
phaseic acid +  
phenylpropiolic acid 
propynoic acid +  
retinoic acid +   
sedanonic acid 
shikimic acid +   
sorbic acid +   
torvanol A hydrogen sulfate 
trans-2-icosenoic acid +  
trans-2-pentadecenoic acid +  
trichostatic acid +   
triptobenzene D 
triptobenzene H 
triptoditerpenic acid B 
triptohairic acid 
triptoquinone A 
TX-1875 
unsaturated heparin disaccharide +  
urocanic acid +   
valanimycin 
zealexin A1 

Synonyms
Related Synonyms: (2E,4E)-2,4-hexadienoic acid ;   (E,E)-1,3-pentadiene-1-carboxylic acid ;   (E,E)-2,4-hexadienoic acid ;   (E,E)-SA ;   (E,E)-sorbic acid ;   1,3-pentadiene-1-carboxylic acid ;   Formula=C6H8O2 ;   InChI=1S/C6H8O2/c1-2-3-4-5-6(7)8/h2-5H,1H3,(H,7,8)/b3-2+,5-4+ ;   InChIKey=WSWCOQWTEOXDQX-MQQKCMAXSA-N ;   SA ;   SMILES=C\\C=C\\C=C\\C(O)=O ;   alpha-trans-gamma-trans-sorbic acid ;   trans,trans-2,4-hexadienoic acid ;   trans,trans-SA ;   trans,trans-sorbic acid
Xrefs: Beilstein:1098547 "Beilstein" ;   CAS:110-44-1 "ChemIDplus" ;   CAS:110-44-1 "NIST Chemistry WebBook" ;   Gmelin:260824 "Gmelin" ;   Gmelin:3063 "Gmelin" ;   LIPID_MAPS_instance:LMFA01030100 "LIPID MAPS"
Xref Mesh: MESH:D013011
Xrefs: PMID:11206806 "Europe PMC" ;   PMID:7979442 "Europe PMC"
Cyclic Relationships: is_conjugate_acid_of CHEBI:77869

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.