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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
2-aminopurines +     
guanine +   
oxopurine +     
(R)-temafloxacin +  
(S)-temafloxacin +  
1',3'-dimethylspiro[1H-indole-3,8'-7,9-dihydropurine]-2,2',6'-trione 
1,1-dihydroxy-3-ethoxy-2-butanone 
1,3,7-trimethyl-5-hydroxyisouric acid 
1,3,7-trimethyl-8-(phenylmethyl)purine-2,6-dione 
1,3,7-trimethylisoguanine 
1,3,7-trimethyluric acid  
1,3-dibutyl-7-(2-oxopropyl)purine-2,6-dione 
1,3-dimethyl-7-(5-oxohexyl)purine-2,6-dione 
1,3-dimethyl-7-(phenylmethyl)-8-[2-(thiophen-2-ylmethylidene)hydrazinyl]purine-2,6-dione 
1,3-dimethyl-8-(3-methyl-1-piperidinyl)-7-[2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]ethyl]purine-2,6-dione 
1,3-dimethyl-8-[2-(1-pyrrolidinyl)ethylthio]-6-sulfanylidene-7H-purin-2-one 
1,3-dimethyl-8-[[methyl-(phenylmethyl)amino]methyl]-7-(2-methylpropyl)purine-2,6-dione 
1,3-dimethyl-8-[methyl-(phenylmethyl)amino]-7-[2-(2-pyrimidinylthio)ethyl]purine-2,6-dione 
1,3-dimethyluric acid 
1,7-dimethyluric acid  
1,N(2)-ethenoguanine 
1-[(2-hydroxyethoxy)methyl]-6-(phenylsulfanyl)thymine 
1-methyl-3-propyl-7H-xanthine 
1-methyluric acid  
2',3'-secoguanosine 
2-(1,3-dimethyl-2,6-dioxo-7-purinyl)-N'-[2-(2-ethoxyphenoxy)-1-oxoethyl]acetohydrazide 
2-(1,3-dimethyl-2,6-dioxo-7-purinyl)-N-(phenylmethyl)-N-(2-pyridinyl)acetamide 
2-(1,3-dimethyl-2,6-dioxo-7-purinyl)-N-[3-[(4-methoxyphenyl)sulfamoyl]-4-methylphenyl]acetamide 
2-(1,3-dimethyl-2,6-dioxo-7-purinyl)acetic acid 
2-(\{8-[(3R)-3-aminopiperidin-1-yl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl\}methyl)benzonitrile 
2-[(1,3-dimethyl-2,6-dioxo-7-propyl-8-purinyl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide 
2-[(7-ethyl-1,3-dimethyl-2,6-dioxo-8-purinyl)thio]-N-(6-methyl-2-pyridinyl)acetamide 
2-[[3-methyl-7-(3-methylbutyl)-2,6-dioxo-8-purinyl]thio]propanoic acid methyl ester 
2-[[7-(3-chlorobut-2-enyl)-3-methyl-2,6-dioxo-8-purinyl]thio]butanoic acid ethyl ester 
2-aminopurine +   
2-furancarboxylic acid [4-[[[1,3-dimethyl-2,6-dioxo-7-(phenylmethyl)-8-purinyl]hydrazinylidene]methyl]phenyl] ester 
2-phenoxyethanol +  
3,5-dimethyl-4-isoxazolecarboxylic acid (3-butyl-2,6-dioxo-7-propyl-8-purinyl)methyl ester 
3,7-dimethyl-1-(phenylmethyl)-8-[(phenylmethyl)amino]purine-2,6-dione 
3,7-dimethylisoguanine 
3,7-dimethyluric acid 
3-butyl-8-(2-fluorophenyl)-7-(phenylmethyl)purine-2,6-dione 
3-isobutyl-1-methylxanthine +   
3-methyl-7-(2-phenylethyl)-8-(propylamino)purine-2,6-dione 
3-methyl-7-(phenylmethyl)-8-(propan-2-ylthio)purine-2,6-dione 
3-methyl-7-[(4-methylphenyl)methyl]-8-[2-(1-piperidinyl)ethylthio]purine-2,6-dione 
3-methyl-7-pentyl-8-(2-phenylethylthio)purine-2,6-dione 
4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)benzenesulfonic acid 
4-[(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)methylamino]benzoic acid 
4-[2-[2-[3-methyl-2,6-dioxo-8-(1-piperidinyl)-7-purinyl]ethylidene]hydrazinyl]benzoic acid 
4-[7-(2-methoxyethyl)-2,6-dioxo-3-(phenylmethyl)-8-purinyl]benzonitrile 
4-[[7-[(4-fluorophenyl)methyl]-1,3-dimethyl-2,6-dioxo-8-purinyl]methyl]-1-piperazinecarboxylic acid ethyl ester 
5-\{[(2-amino-9H-purin-6-yl)oxy]methyl\}pyrrolidin-2-one 
5-hydroxyisouric acid +  
5-hydroxyisouric acid anion 
5-iodo-2'-deoxyuridine  
6-(9'-Purine-6',8'-diolyl)-2beta-suberosanone 
6-(tetrahydrofuran-2-ylmethoxy)-9H-purin-2-amine 
6-chloroguanine 
6-methylthioguanine 
6-Thiourate  
7,8-dihydro-8-oxoguanine  
7-(2-chloroethyl)-1,3-dimethylpurine-2,6-dione 
7-(2-ethoxyethyl)-3-methyl-8-(1-pyrrolidinyl)purine-2,6-dione 
7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione 
7-(2-methoxyethyl)-3-methyl-8-(phenylthio)purine-2,6-dione 
7-(3-chlorobut-2-enyl)-1,3-dimethyl-8-(2-phenylethylamino)purine-2,6-dione 
7-(3-methoxypropyl)-3-(phenylmethyl)-8-(3-thiophenyl)purine-2,6-dione 
7-(5-O-phosphono-alpha-D-ribofuranosyl)-7H-purin-2-amine 
7-[(2-chloro-6-fluorophenyl)methyl]-1,3-dimethyl-8-(1-piperidinylmethyl)purine-2,6-dione 
7-[(2-chloro-6-fluorophenyl)methyl]-1,3-dimethyl-8-[(3-methyl-1-piperidinyl)methyl]purine-2,6-dione 
7-[(3-bromophenyl)methyl]-1,3-dimethyl-8-(2-methylpropylamino)purine-2,6-dione 
7-[(3-bromophenyl)methyl]-1,3-dimethyl-8-(3-pyridinylmethylamino)purine-2,6-dione 
7-[(4-fluorophenyl)methyl]-1,3-dimethyl-8-[(2-oxo-2-thiophen-2-ylethyl)thio]purine-2,6-dione 
7-[2-(1,3-benzothiazol-2-ylthio)ethyl]-1,3-dimethyl-8-(3-methyl-1-piperidinyl)purine-2,6-dione 
7-[2-hydroxy-3-(2-methylphenoxy)propyl]-3-methyl-8-(propan-2-ylthio)purine-2,6-dione 
7-[2-hydroxy-3-(4-methoxyphenoxy)propyl]-1,3-dimethyl-8-(1-piperidinyl)purine-2,6-dione 
7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethylpurine-2,6-dione 
7-\{2-hydroxy-3-[(naphthalen-1-yl)oxy]propyl\}-3-methyl-8-(morpholin-4-yl)-3,7-dihydropurine-2,6-dione 
7-benzyl-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydropurine-2,6-dione 
7-but-2-enyl-3-methyl-8-(3-phenylpropylthio)purine-2,6-dione 
7-but-2-enyl-3-methyl-8-(phenylmethylthio)purine-2,6-dione 
7-Methyluric acid 
7-methylxanthine 
8-(1,3-benzothiazol-2-ylthio)-3-methyl-7-pentylpurine-2,6-dione 
8-(2,5-dimethylphenoxy)-1,3-dimethyl-7-prop-2-enylpurine-2,6-dione 
8-(3-ethoxypropylamino)-1,3-dimethyl-7H-purine-2,6-dione 
8-(4-methoxyphenyl)-7-methyl-3-(phenylmethyl)purine-2,6-dione 
8-(butan-2-ylthio)-7-[(4-chlorophenyl)methyl]-3-methylpurine-2,6-dione 
8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione 
8-[(1-ethyl-3-piperidinyl)thio]-1,3-dimethyl-6-sulfanylidene-7H-purin-2-one 
8-[(2-fluoroanilino)hydrazinylidene]-1,3-dimethylpurine-2,6-dione 
8-[2-(2-bromo-3-phenylprop-2-enylidene)hydrazinyl]-7-(2-hydroxyethyl)-3-methylpurine-2,6-dione 
8-[[4-[2-furanyl(oxo)methyl]-1-piperazinyl]methyl]-1,3-dimethyl-7-[(2-methylphenyl)methyl]purine-2,6-dione 
8-[[4-[2-furanyl(oxo)methyl]-1-piperazinyl]methyl]-1,3-dimethyl-7-propylpurine-2,6-dione 
8-anilino-1,3-dimethyl-7H-purine-2,6-dione 
8-cyclopentyl-1,3-dimethyl-7H-purine-2,6-dione 
8-hydroxy-7-methylguanine 
8-oxoadenine 
8-oxoguanine 
8-phenyl-1,3-dipropyl-7H-purine-2,6-dione 
9-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)guanine 
9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purin-2-amine 
9-[2-(phosphonomethoxy)ethyl]guanine  
9-\{2-deoxy-5-O-hydroxyphosphonoyl-beta-D-ribofuranosyl\}-9H-purin-2-amine 
9-aminoacridine  
9-aminoacridine hydrochloride 
9-Methylxanthine 
abacavir +   
acyclovir  
adefovir +   
adefovir pivoxil  
amantadine  
amantadine sulfate 
aminocandin 
amphotericin B methyl ester  
amprenavir  
antifungal drug +   
antimicrobial drug +   
antiparasitic agent +   
antiseptic drug +   
aphidicolin  
atazanavir +   
bamifylline 
benzoylmesaconine  
bicozamycin 
BIIB021 
boceprevir 
brodimoprim 
cafaminol 
cafedrine 
carbovir +  
caspofungin +   
caspofungin acetate 
cerulenin  
chlorhexidine +   
cidofovir anhydrous +   
cidofovir dihydrate 
cilofungin 
cinoxacin  
ciprofloxacin +   
ciprofloxacin dihydrochloride 
ciprofloxacin hydrochloride (anhydrous) +  
ciprofloxacin hydrochloride hydrate 
clotrimazole  
costunolide +   
cycloguanil +  
D-cycloserine +   
daclatasvir 
daclatasvir hydrochloride 
dapsone +   
darunavir +  
dasabuvir 
dasabuvir sodium +  
dasabuvir sodium hydrate +  
delavirdine +   
delavirdine mesylate 
Descovy 
didanosine  
dimethazan 
doxofylline 
DPCPX  
dyphylline +  
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor +   
Echinacea extract 
echinocandin B 
efavirenz  
elbasvir +  
emivirine 
emtricitabine +   
enprofylline +  
entecavir (anhydrous) +  
entecavir hydrate 
Epclusa 
etamiphylline 
etofylline clofibrate 
etofylline nicotinate 
famciclovir 
fenetylline 
fenticlor 
floxuridine  
furagin 
furazolidone  
ganciclovir +   
An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections.
gatifloxacin +   
gemcitabine +   
gemcitabine hydrochloride 
geneticin  
Genvoya 
grazoprevir +  
guanin-9-yl group +  
guanine +   
guanosine +   
guanosines +   
guanyl deoxyribonucleotide residue +  
guanyl nucleotide +   
Harvoni 
HIV fusion inhibitor +   
hypoxanthine +   
hypoxanthine 3-N-oxide +  
isoguanine 
istradefylline  
lamivudine  
ledipasvir +  
lopinavir  
LSM-1748 
maraviroc  
mecillinam +  
methylguanine +   
methylhypoxanthine +  
micafungin 
Migrenin (TN) 
N(2),3-ethenoguanine 
N(2)-(ADP-D-ribosyl)-guanine(2-) 
N(2)-carboxyethylguanine 
N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide 
N-acetyl-L-cysteinate 
N-acetyl-L-cysteine +   
nelarabine 
nevirapine +   
nifurtoinol 
nitrofurantoin  
nitroxoline  
O(6)-methyl-2'-deoxyguanosine 
O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE 
Odefsey 
ofloxacin +   
ombitasvir +  
ornidazole  
oseltamivir +   
oseltamivir acid 
oxiconazole  
oxiconazole nitrate 
oxolinic acid 
paritaprevir +  
pefloxacin +  
penciclovir 
pentifylline 
Pentoxifylline  
peramivir 
peramivir hydrate +  
phentetramine 
phosphonoformic acid +   
pimefylline 
pivmecillinam +  
Prezcobix 
Propentofylline 
protheobromine 
Proxyphylline 
puromycin +   
raltegravir 
reproterol 
ribavirin  
ritonavir +   
rosoxacin 
salicylic acid +   
saquinavir  
seliciclib 
sofosbuvir +  
solasodine  
solasodine(1+) +  
sulfacetamide 
sulfacetamide sodium 
sulfacetamide sodium anhydrous +  
sulfadiazine  
sulfadimethoxine  
sulfaguanidine 
sulfamerazine  
sulfamethazine +   
sulfamethizole 
sulfamethoxazole +   
sulfamethoxydiazine 
sulfamethoxypyridazine 
sulfapyridine  
sulfasalazine  
sulfathiazole +  
sulfisomidine  
tazobactam  
tazobactam sodium +  
Technivie 
telaprevir  
telbivudine 
temafloxacin 
tenofovir (anhydrous) +   
tenofovir alafenamide 
tenofovir alafenamide fumarate +  
tenofovir disoproxil +   
tenofovir disoproxil fumarate  
tenofovir hydrate 
tenofovir(1-) 
Theacrine 
theodrenaline 
Theophylline sodium acetate 
tioconazole 
tioguanine +   
tipranavir  
tosufloxacin 
tosufloxacin tosylate +  
tosufloxacin tosylate hydrate 
trifluridine +   
trisodium phosphonoformate +  
trisodium phosphonoformate hexahydrate 
urate(2-) +  
uric acid +   
valacyclovir 
valganciclovir 
velpatasvir +  
Viekira Pak 
xanthine +   
zalcitabine  
Zepatier 
Zerbaxa 
zidovudine  

Synonyms
Exact Synonyms: 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-1,9-dihydro-6H-purin-6-one
Related Synonyms: 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol ;   2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one ;   2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one ;   2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one ;   2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol ;   2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone ;   9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine ;   9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE ;   9-[(1,3-dihydroxy-2-propoxy)methyl]guanine ;   Formula=C9H13N5O4 ;   GA2 ;   InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17) ;   InChIKey=IRSCQMHQWWYFCW-UHFFFAOYSA-N ;   SMILES=Nc1nc2n(COC(CO)CO)cnc2c(=O)[nH]1 ;   ganciclovirum ;   gancyclovir
Alternate IDs: CHEBI:42659 ;   CHEBI:5273
Xrefs: Beilstein:3654487 "Beilstein" ;   CAS:82410-32-0 "ChemIDplus" ;   CAS:82410-32-0 "DrugBank" ;   CAS:82410-32-0 "KEGG COMPOUND" ;   CAS:82410-32-0 "KEGG DRUG" ;   DrugBank:DB01004 ;   Drug_Central:1277 "DrugCentral" ;   HMDB:HMDB0015139 ;   KEGG:D00333 ;   LINCS:LSM-5382
Xref Mesh: MESH:D015774
Xrefs: PDBeChem:GA2 ;   PMID:10197958 "ChEMBL" ;   PMID:10377226 "ChEMBL" ;   PMID:10411487 "ChEMBL" ;   PMID:10447945 "ChEMBL" ;   PMID:10560739 "ChEMBL" ;   PMID:10691698 "ChEMBL" ;   PMID:10882370 "ChEMBL" ;   PMID:10882372 "ChEMBL" ;   PMID:10882374 "ChEMBL" ;   PMID:10882375 "ChEMBL" ;   PMID:10888336 "ChEMBL" ;   PMID:10966740 "ChEMBL" ;   PMID:10966745 "ChEMBL" ;   PMID:10999475 "ChEMBL" ;   PMID:11229780 "ChEMBL" ;   PMID:11262090 "ChEMBL" ;   PMID:11412988 "ChEMBL" ;   PMID:11454465 "ChEMBL" ;   PMID:11472207 "ChEMBL" ;   PMID:11495586 "ChEMBL" ;   PMID:11585457 "ChEMBL" ;   PMID:11677126 "ChEMBL" ;   PMID:11708924 "ChEMBL" ;   PMID:11708929 "ChEMBL" ;   PMID:11754587 "ChEMBL" ;   PMID:11814776 "ChEMBL" ;   PMID:11858989 "ChEMBL" ;   PMID:11985471 "ChEMBL" ;   PMID:12408716 "ChEMBL" ;   PMID:12459010 "ChEMBL" ;   PMID:12723951 "ChEMBL" ;   PMID:1310744 "ChEMBL" ;   PMID:1319491 "ChEMBL" ;   PMID:1323678 "ChEMBL" ;   PMID:14521407 "ChEMBL" ;   PMID:14584954 "ChEMBL" ;   PMID:14643328 "ChEMBL" ;   PMID:14643358 "ChEMBL" ;   PMID:14736238 "ChEMBL" ;   PMID:15027877 "ChEMBL" ;   PMID:15081019 "ChEMBL" ;   PMID:15481985 "ChEMBL" ;   PMID:15509173 "ChEMBL" ;   PMID:15509174 "ChEMBL" ;   PMID:15509175 "ChEMBL" ;   PMID:15509176 "ChEMBL" ;   PMID:15615545 "ChEMBL" ;   PMID:15634003 "ChEMBL" ;   PMID:15658858 "ChEMBL" ;   PMID:15658861 "ChEMBL" ;   PMID:15658873 "ChEMBL" ;   PMID:15689173 "ChEMBL" ;   PMID:15745823 "ChEMBL" ;   PMID:15801851 "ChEMBL" ;   PMID:16134946 "ChEMBL" ;   PMID:16392791 "ChEMBL" ;   PMID:16392824 "ChEMBL" ;   PMID:16420056 "ChEMBL" ;   PMID:16480257 "ChEMBL" ;   PMID:1652016 "ChEMBL" ;   PMID:16759112 "ChEMBL" ;   PMID:16814545 "ChEMBL" ;   PMID:17004726 "ChEMBL" ;   PMID:17043128 "ChEMBL" ;   PMID:17092728 "ChEMBL" ;   PMID:17161946 "ChEMBL" ;   PMID:17181158 "ChEMBL" ;   PMID:17181162 "ChEMBL" ;   PMID:17188402 "ChEMBL" ;   PMID:17239594 "ChEMBL" ;   PMID:17298047 "ChEMBL" ;   PMID:17329103 "ChEMBL" ;   PMID:17402726 "ChEMBL" ;   PMID:17434304 "ChEMBL" ;   PMID:17438061 "ChEMBL" ;   PMID:17513108 "ChEMBL" ;   PMID:17518459 "ChEMBL" ;   PMID:17539622 "ChEMBL" ;   PMID:17622128 "ChEMBL" ;   PMID:17672445 "ChEMBL" ;   PMID:17869124 "ChEMBL" ;   PMID:17948980 "ChEMBL" ;   PMID:17960926 "ChEMBL" ;   PMID:18082410 "ChEMBL" ;   PMID:1849998 "ChEMBL" ;   PMID:2157013 "ChEMBL" ;   PMID:2160539 "ChEMBL" ;   PMID:2163453 "ChEMBL" ;   PMID:2163454 "ChEMBL" ;   PMID:2165163 "ChEMBL" ;   PMID:2175356 "ChEMBL" ;   PMID:2329551 "ChEMBL" ;   PMID:2329561 "ChEMBL" ;   PMID:2391689 "ChEMBL" ;   PMID:2500527 "ChEMBL" ;   PMID:2544723 "ChEMBL" ;   PMID:2822928 "ChEMBL" ;   PMID:2826784 "ChEMBL" ;   PMID:2840500 "ChEMBL" ;   PMID:2842505 "ChEMBL" ;   PMID:2846837 "ChEMBL" ;   PMID:2848125 "ChEMBL" ;   PMID:2913300 "ChEMBL" ;   PMID:2989523 "ChEMBL" ;   PMID:2993615 "ChEMBL" ;   PMID:3009811 "ChEMBL" ;   PMID:3016263 "ChEMBL" ;   PMID:3871860 "ChEMBL" ;   PMID:7562929 "ChEMBL" ;   PMID:7562946 "ChEMBL" ;   PMID:7562947 "ChEMBL" ;   PMID:7752205 "ChEMBL" ;   PMID:7877148 "ChEMBL" ;   PMID:7932543 "ChEMBL" ;   PMID:8071942 "ChEMBL" ;   PMID:8176714 "ChEMBL" ;   PMID:8254613 "ChEMBL" ;   PMID:8394933 "ChEMBL" ;   PMID:8632412 "ChEMBL" ;   PMID:8709116 "ChEMBL" ;   PMID:8765514 "ChEMBL" ;   PMID:8784444 "ChEMBL" ;   PMID:8784445 "ChEMBL" ;   PMID:8941388 "ChEMBL" ;   PMID:9046339 "ChEMBL" ;   PMID:9057866 "ChEMBL" ;   PMID:9057867 "ChEMBL" ;   PMID:9057868 "ChEMBL" ;   PMID:9216836 "ChEMBL" ;   PMID:9438017 "ChEMBL" ;   PMID:9548814 "ChEMBL" ;   PMID:9575044 "ChEMBL" ;   PMID:9836613 "ChEMBL" ;   PMID:9836626 "ChEMBL" ;   PMID:9871553 "ChEMBL" ;   PMID:9925738 "ChEMBL" ;   PMID:9934470 "ChEMBL" ;   PMID:9934471 "ChEMBL" ;   Patent:US4355032 ;   Reaxys:3654487 "Reaxys" ;   Wikipedia:Ganciclovir

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.