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Term:
Parent Terms Term With Siblings Child Terms
dicarboximide +     
pyrrolidinone +     
(3-amino-2,5-dioxopyrrolidin-1-yl)acetic acid 
(3S)-tetrahydrofuran-3-yl (1R,2S)-3-[4-((1R)-2-\{[(S)-amino(hydroxy)methyl]oxy\}-2,3-dihydro-1H-inden-1-yl)-2-benzyl-3-oxopyrrolidin-2-yl]-1-benzyl-2-hydroxypropylcarbamate 
(4R)-2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetrone 
(R)-efonidipine +  
(R)-oxybutynin +   
(S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propionic acid 
(S)-4,4'-(1-methylethane-1,2-diyl)bis(piperazine-2,6-dione) 
(S)-efonidipine +  
2-[5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione +  
2-aminoethoxydiphenylborane  
3'-Demethoxypiplartine 
3-(11,11-dimethyl-8-methylene-4-oxo-5-bicyclo[7.2.0]undecanyl)oxolane-2,5-dione 
3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione +   
4-(5-amino-1,2,4-oxadiazol-3-yl)-1,2,5-oxadiazol-3-amine 
4-[4-(2,5-dioxopyrrolidin-1-yl)phenylamino]-4-hydroxybutyric acid 
4-[5-(4-methyl-1,2,5-oxadiazol-3-yl)-1H-1,2,4-triazol-3-yl]-1,2,5-oxadiazol-3-amine 
4-amino-1,8-naphthalimide +   
5,7-dihydroxy-4'-methoxyflavone +   
5-(2,2-diferuloylethen-1-yl)thalidomide 
5-[2-(feruloyl)ethen-1-yl]thalidomide 
5-chlorospiro[indole-3,2'-[1,3]oxathiolan]-2(1H)-one 
7-(diethylamino)-N-[(Z)-2-(2,5-dioxopyrrolidin-1-yl)vinyl]-2-oxo-2H-chromene-3-carboxamide 
\{[(1r,7r)-4-(4-acetamidophenyl)-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-1-yl]carbamoyloxy\}acetic acid 
acetazolamide +   
adinazolam  
Alexa Fluor 350 
Alexa Fluor 430 
Alexa Fluor 430(1-) +  
alpha-asarone 
alprazolam  
aminoglutethimide +   
amlodipine +   
amlodipine benzenesulfonate +  
asperparaline A 
ATTO 425-3 
ATTO 465-3 
ATTO 465-4 
ATTO 495-3 
ATTO 495-4 
ATTO 520-3 
ATTO 520-4 
ATTO 610-3 
ATTO 610-4 
ATTO 635-3 
ATTO 635-4 
barbinine 
bepridil +   
bevantolol +   
bevantolol hydrochloride +  
Blue pigment 
BODIPY 630/650-X 
BODIPY 650/665-X 
BODIPY FL-X 
BODIPY TMR-X 
BODIPY TR-X 
brivaracetam 
carbamazepine +   
carnosine +   
cascade yellow 
CGP 78608 
CGP 78608 hydrochloride 
Chrome fast yellow 8GL (acid form) 
cilnidipine  
cinnarizine  
cinolazepam 
cladoniamide A 
cladoniamide B 
cladoniamide C 
clobazam  
clonazepam  
clorazepic acid 
cobalt dichloride +   
cromoglycic acid 
cycloheximide  
cyclopiazonic acid +   
dabcyl SE dye 
devapamil 
diacetylspermidine 
diazepam +   
dicarboximide antifungal agent +   
didesethylflurazepam 
diethylstilbestrol +   
diltiazem  
diltiazem hydrochloride 
diltiazem(1+) +  
dipotassium clorazepate 
dotarizine 
efonidipine 
elatine 
eslicarbazepine acetate 
esoxybutynin +   
estazolam  
ethosuximide +   
A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
ethotoin +   
ethyl 3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-1,3-oxazolidine-5-carboxylate +   
eupatorin  
ezogabine  
felbamate  
felodipine  
flumioxazin 
flurazepam +   
Formothion 
gabapentin +   
gabapentin enacarbil 
gamma-decalactone  
glutaurine 
glutaurine zwitterion 
glutaurine(1-) 
hentriacontan-16-one 
hispidulin  
indigoidine 
IWR-1-endo 
IWR-1-exo 
L-3-aminosuccinimide 
L-cycloserine +  
L-glutamimide 
L-lysine +   
lamotrigine  
lenalidomide  
levetiracetam  
licarbazepine +  
lissamine flavine FF free acid 
lurasidone 
magnesium sulfate +   
maleimide +   
maleimides +   
malyngamide A 
Mecarphon 
meclofenamic acid  
melatonin +   
mephenytoin  
mephobarbital  
midazolam +   
midazolam hydrochloride 
N(1)-[(3R)-1-((2S)-2-\{[(benzyloxy)carbonyl]amino\}-4-methylpentyl)-4-oxopyrrolidin-3-yl]-N(2)-[(pyridin-4-ylmethoxy)carbonyl]-L-leucinamide 
N(2)-[(benzyloxy)carbonyl]-N(1)-((3R)-1-\{N-[(benzyloxy)carbonyl]-L-leucyl\}-4-oxopyrrolidin-3-yl)-L-leucinamide 
N-(3,4-dihydro-2H-pyrrol-5-yl)-5-(2-furanyl)-1,3,4-oxadiazol-2-amine 
N-[(3S)-2-oxo-1-(1H-pyrrolo[2,3-c]pyridin-2-ylmethyl)pyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide 
N-[(5-methyl-1,2-oxazol-3-yl)carbonyl]-L-alanyl-L-valyl-N-\{(2S,3E)-5-(benzyloxy)-5-oxo-1-[(3R)-2-oxopyrrolidin-3-yl]pent-3-en-2-yl\}-L-leucinamide 
N-\{[2-(3-chloro-4-fluorophenyl)hydrazino]carbonyl\}-3,5-bis(methylthio)isothiazole-4-carboxamide 
N-arachidonoylserotonin 
N-bromosuccinimide 
N-chlorosuccinimide 
N-ethylsuccinimide +  
N-iodosuccinimide 
N-Phenylacetyl pyroglutamic acid 
N-succinimidyl N-methylcarbamate 
nemadipine-A 
nickel dichloride +   
nifedipine  
nimetazepam  
nimodipine  
nisoldipine  
nitrazepam +   
nitrendipine  
nordazepam  
norverapamil  
nygerone A 
ochratoxin A +   
ochratoxin B  
omega-conotoxin GVIA  
omeprazole +   
otophylloside B 
oxcarbazepine  
oxoproline +   
oxybutynin +   
palmitoyl ethanolamide  
Palmyrrolinone 
perampanel +  
perampanel hydrate 
perylenediimide 
pestalamide A 
pestalamide B 
phenobarbital +   
phenytoin  
phthalimides +   
piperidine-2,6-dione +   
Piplartine  
pomalidomide  
pregabalin  
prilocaine +  
primidone  
propofol +   
pyflubumide 
pyroglutamine 
pyrrolidin-2-ones +   
pyrrolidine dithiocarbamate  
QSY35 succinimidyl ester 
SKF-96365 hydrochloride  
sodium meclofenamate monohydrate 
sodium selenate 
solasodine  
solasodine(1+) +  
streptolydigin 
succinimide +  
tandospirone 
tarocin A 
tarocin A1 
tarocin A2 
terrylendiimide 
thalidomide +   
thapsigargin  
thiopental  
tiagabine  
tiagabine hydrochloride 
topiramate  
tranilast  
trioctanoin 
troglitazone  
U50488  
valproate semisodium 
valproic acid +   
vanillin +   
verapamil  
vigabatrin  
zaleplon  
zofenopril 
zofenopril calcium 
zofenoprilat 
zofenoprilat arginine 
zonisamide  

Synonyms
Exact Synonyms: 3-ethyl-3-methylpyrrolidine-2,5-dione
Related Synonyms: 2-ethyl-2-methylsuccinimide ;   2-methyl-2-ethylsuccinimide ;   3-ethyl-3-methyl-2,5-pyrrolidinedione ;   3-ethyl-3-methylsuccinimide ;   3-methyl-3-ethylpyrrolidine-2,5-dione ;   3-methyl-3-ethylsuccinimide ;   Aethosuximide ;   Formula=C7H11NO2 ;   InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10) ;   InChIKey=HAPOVYFOVVWLRS-UHFFFAOYSA-N ;   SMILES=CCC1(C)CC(=O)NC1=O ;   alpha-ethyl-alpha-methylsuccinimide ;   alpha-methyl-alpha-ethylsuccinimide ;   ethosuximidum ;   etosuximida ;   gamma-methyl-gamma-ethyl-succinimide
Alternate IDs: CHEBI:131811
Xrefs: CAS:77-67-8 ;   DrugBank:DB00593 ;   Drug_Central:1087 ;   HMDB:HMDB0014731 ;   KEGG:C07505 ;   KEGG:D00539 ;   LINCS:LSM-5195
Xref Mesh: MESH:D005013
Xrefs: PMID:12873507 ;   PMID:1681105 ;   PMID:17011080 ;   PMID:17046248 ;   PMID:17451232 ;   PMID:17481896 ;   PMID:1847429 ;   PMID:19005061 ;   PMID:1992141 ;   PMID:2061925 ;   PMID:21332949 ;   PMID:21945797 ;   PMID:2296016 ;   PMID:2308142 ;   PMID:3336019 ;   PMID:3820228 ;   PMID:8246220 ;   PMID:8627613 ;   PMID:8691481 ;   PMID:9016327 ;   Reaxys:117054 ;   Wikipedia:Ethosuximide

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.