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Term:
Parent Terms Term With Siblings Child Terms
antimalarial +   
tetracyclines +     
(+)-(11R,2'S)-erythro-mefloquine +   
(+)-artemisinin +   
(-)-(11S,2'R)-erythro-mefloquine +   
(4aS,5aR,12aS)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
(4R,12aR)-4,7-bis(dimethylamino)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
(4S,4aR,5S,12aS)-7-chloro-4-(dimethylamino)-5,10,12a-trihydroxy-6-methylene-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
(4S,4aS,5aR,12aS)-9-[[2-(tert-butylamino)-1-oxoethyl]amino]-4,7-bis(dimethylamino)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
(4S,4aS,5aR,6S,12aS)-7-chloro-4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
(4S,4aS,6S,12aS)-7-chloro-4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
(R)-7-butyl-6,8-dihydroxy-3-[(3E)-pent-3-en-1-yl]-3,4-dihydroisochromen-1-one 
(R)-iclaprim +  
(R)-temafloxacin +  
(S)-iclaprim +  
(S)-temafloxacin +  
11a-hydroxy-7-iodotetracycline zwitterion 
11a-hydroxychlortetracycline zwitterion 
11a-hydroxytetracycline 
11a-hydroxytigecycline(1+) 
12-dehydrotetracycline 
2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone 
3,15-di-O-acetylbruceolide 
3-(Z)-caffeoyllupeol 
4-(dimethylamino)-5,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
4-\{((R)-2-Carboxy-3-methoxymethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-7-ylcarbamoyl)-[(Z)-methoxyimino]-methyl\}-thiazol-2-yl-ammonium +  
4-amino-4-de(dimethylamino)anhydrotetracycline 
4-Aminoanhydrochlortetracycline 
4-de(dimethylamino)-4-oxoanhydrotetracycline 
4-Dedimethylamine-4-oxo-anhydro-7-Cl-tetracycline 
5,7,3'-trihydroxy-4',5'-(2'''',2''''-dimethylpyran)-8,2'-di(3-methyl-2-butenyl)-(2S)-flavanone 
5-O-methylcelebixanthone 
5a,11a-Dehydrochlortetracycline 
5a,11a-dehydrooxytetracycline 
7-chloro-4-(dimethylamino)-6,10,12a-trihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
7-deacetylgedunin 
8-azahypoxanthine 
a tetracycline zwittterion +  
acedapsone 
amburoside A 
amikacin  
amikacin disulfate 
amodiaquine +   
amoxicillin +   
amoxicillin trihydrate +   
ampicillin +   
Anhydrochlortetracycline 
anhydrotetracycline +  
antimycobacterial drug +   
antitreponemal drug +  
apramycin 
arasertaconazole +   
arbekacin +  
artemether  
artesunate  
atovaquone  
Augmentin  
avibactam 
avibactam sodium +  
Avycaz 
azithromycin +   
azlocillin 
aztreonam +   
bauhinoxepin F 
bauhinoxepin I 
bauhinoxepin J 
benzyl isothiocyanate  
benzylpenicillin +   
betulinic acid +   
biapenem 
bidebiline C 
bidebiline D 
bielschowskysin 
bipinnatone A 
bipinnatone B 
BMS-192548 
borrelidin  
brodimoprim 
bromophycolide A 
bruceolide +  
caesalpinin C 
caesalpinin D 
caesalpinin F 
callophycoic acid A 
callophycoic acid B 
callophycoic acid C 
callophycoic acid D 
callophycoic acid E 
callophycoic acid F 
callophycoic acid G 
callophycoic acid H 
callophycol A 
callophycol B 
carbapenem MM22383 
carbenicillin +  
caribenol A 
caribenol B 
carumonam 
caseargrewiin A 
caseargrewiin B 
caseargrewiin C 
caseargrewiin D 
cassiarin A 
cassiarin B 
cefaclor  
cefadroxil +   
cefaloridine  
cefalotin +   
cefamandole +  
cefamandole nafate 
cefamandole sodium 
cefatrizine 
cefazedone 
cefazolin  
cefcapene 
cefdaloxime 
cefdinir  
cefditoren +  
cefditoren pivoxil 
cefepime  
cefepime hydrochloride 
cefiderocol 
cefixime  
cefmenoxime +  
cefmetazole  
cefodizime 
cefonicid  
cefoperazone  
ceforanide 
cefotaxime  
cefotetan  
cefotetan disodium 
cefotiam +   
cefotiam dihydrochloride 
cefotiam hexetil dihydrochloride 
cefoxitin  
cefpiramide 
cefpodoxime +   
cefpodoxime proxetil 
cefprozil 
cefsulodin 
ceftaroline +  
ceftaroline fosamil +  
ceftaroline fosamil acetate +  
ceftaroline fosamil acetate monohydrate 
ceftazidime +   
ceftibuten +   
ceftibuten dihydrate 
ceftizoxime  
ceftriaxone  
cefuzonam 
celebixanthone +  
cephalexin +   
cephalexin monohydrate 
cephapirin 
cephapirin sodium 
cephradine  
cethromycin 
chloramphenicol +   
chloroquine +   
chlorphenesin +   
chlorquinaldol 
chlortetracycline  
cinoxacin  
ciprofloxacin +   
ciprofloxacin dihydrochloride 
ciprofloxacin hydrochloride (anhydrous) +  
ciprofloxacin hydrochloride hydrate 
clarithromycin  
clavulanic acid 
clometocillin 
clomocycline 
cloxacillin  
co-trimoxazole  
cochinchinone C 
conessine 
cordyheptapeptide A 
cordyol C 
crambescidin 800 
cryptolepine  
cyclacillin 
cycloguanil +  
dalbavancin 
dapsone +   
daptomycin 
demeclocycline +   
demeclocycline hydrochloride 
desmethylanhydrotetracycline 
dicloxacillin  
difloxacin 
dihydroartemisinin  
dioncopeltine A 
dioncophylline A 
dioncophylline C 
diuvaretin 
DMG-MINO 
docetaxel anhydrous +  
doxycycline +   
Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis.
doxycycline hyclate 
doxycycline monohydrate 
dragomabin 
dragonamide A 
E64 
enoxacin  
ertapenem 
ertapenem sodium 
Eunicea sesquiterpenoid 2 
Eunicea sesquiterpenoid 3 
eurycomanone  
exiguaflavanone A 
exiguaflavanone B 
fenticonazole 
fenticonazole nitrate 
fidaxomicin 
finafloxacin 
fleroxacin 
flomoxef 
flucloxacillin +   
flurithromycin 
framycetin +   
fumagillin +   
furagin 
furaltadone 
furazolidone  
garenoxacin 
gedunin +   
gemifloxacin +  
guamecycline 
gutolactone 
hetacillin 
hexamethylenetetramine +  
hirsutellide A 
humulone 
hydroxychloroquine  
iclaprim 
imipenem +   
iodtetracycline(1-) +  
isariotin F 
isoconazole  
isoconazole nitrate 
isonordoperoxide 
josamycin  
kanamycin A sulfate 
lactucin +  
lactucopicrin 
leachianone A 
levofloxacin  
linezolid  
longirostrerone A 
longirostrerone B 
longirostrerone C 
loracarbef 
lumefantrine 
lycorine  
lymecycline 
malachite green cation +   
manzamine A +  
marbofloxacin  
mecillinam +  
meclocycline  
mefloquine  
meropenem +   
meropenem trihydrate 
methacycline 
methicillin +  
methylene blue  
metronidazole +   
metronidazole benzoate 
metronidazole hydrochloride 
mezlocillin 
minocycline +   
minquartynoic acid 
mollicellin B 
mollicellin C 
mollicellin E 
mollicellin J 
mollicellin K 
mollicellin L 
mollicellin M 
moxalactam 
moxifloxacin  
moxifloxacin hydrochloride 
mupirocin 
mupirocin calcium (anhydrous) +  
mupirocin calcium hydrate 
nadifloxacin +  
nafcillin  
nalidixic acid  
nardoperoxide 
neurolenin A 
neurolenin B 
neurolenin C 
neurolenin D 
nifurtoinol 
nitrofurantoin  
nitrofurazone  
norcaesalpinin D 
norcaesalpinin E 
norfloxacin  
norlichexanthone 
nostocarboline 
ofloxacin +   
oritavancin +  
oritavancin bisphosphate 
ornidazole  
oxacillin +   
oxolinic acid 
oxytetracycline  
paromomycin +   
paromomycin sulfate 
pefloxacin +  
pefloxacin mesylate 
penamecillin 
phomoxanthone A 
phomoxanthone B 
physalin B 
physalin D 
physalin F 
physalin G 
pipacycline 
pipemidic acid  
piperacillin +   
piperaquine 
piromidic acid 
pivmecillinam +  
potassium clavulanate +   
pracinostat 
Pretetramid +  
pretetramide +  
primaquine  
pristinamycin 
pristinamycin IA +  
pristinamycin IIA +  
proguanil  
prontosil  
pyrimethamine  
quercetin-7-O-[alpha-L-rhamnopyranosyl(1->6)-beta-D-galactopyranoside] 
quinacrine +   
quinidine +   
quinine +   
quinine sulfate +  
quinine(1+) +   
ribostamycin +  
ribostamycin sulfate 
ristocetin 
robustaside D 
robustaside E 
robustaside F 
robustaside G 
rolitetracycline 
rosoxacin 
roxarsone  
roxithromycin +   
salicylhydroxamic acid  
samaderine B 
samaderine E 
samaderine X 
samaderine Z 
sancycline 
scutianthraquinone A 
scutianthraquinone B 
scutianthraquinone C 
sertaconazole  
sertaconazole nitrate 
silver(1+) sulfadiazinate 
simalikalactone D 
sirolimus +   
sophoraflavanone G 
spectinomycin 
spectinomycin dihydrochloride 
spectinomycin hydrochloride hydrate 
spiramycin I 
spiramycin II 
streptomycin +   
sulfabenzamide 
sulfacetamide 
sulfachloropyridazine 
sulfadoxine 
sulfamazone 
sulfamethazine +   
sulfaperin 
sulfaphenazole  
sulfathiourea 
sulfisoxazole +   
sulfisoxazole diolamine 
tafenoquine 
TAN-1612 
teicoplanin  
telavancin +  
telavancin hydrochloride 
temafloxacin 
tetracycline +   
tetracycline zwitterion 
thiostrepton  
thiram  
tiamulin  
ticarcillin 
tigecycline +   
tinidazole  
triacsin C  
triclosan  
trimethoprim +   
trovafloxacin  
trovafloxacin mesylate 
vancomycin +   
venturamide A 
venturamide B 
virginiamycin 
virginiamycin S1 +  
WLL-vs 
xibornol 

Synonyms
Related Synonyms: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE ;   5-hydroxy-alpha-6-deoxytetracycline ;   6alpha-deoxy-5-oxytetracycline ;   Doxycyclin ;   Formula=C22H24N2O8 ;   InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1 ;   InChIKey=JBIWCJUYHHGXTC-AKNGSSGZSA-N ;   Jenacyclin ;   SMILES=[H][C@@]12[C@@H](C)c3cccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]2O ;   Supracyclin ;   Vibramycin ;   doxiciclina ;   doxycycline (anhydrous) ;   doxycyclinum
Alternate IDs: CHEBI:42135 ;   CHEBI:4713
Xrefs: Beilstein:3041790 "Beilstein" ;   CAS:564-25-0 "ChemIDplus" ;   CAS:564-25-0 "KEGG COMPOUND" ;   DrugBank:DB00254 ;   Drug_Central:961 "DrugCentral" ;   KEGG:C06973 ;   KEGG:D07876 ;   KNApSAcK:C00017127
Xref Mesh: MESH:D004318
Xrefs: PDBeChem:DXT ;   PMID:1650428 "Europe PMC" ;   Patent:US3019260 ;   Patent:US3200149 ;   Reaxys:3041790 "Reaxys" ;   VSDB:1840 ;   Wikipedia:Doxycycline

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.