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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
(11R,16S)-misoprostol +   
16,16-dimethylprostaglandin E2  
aloin 
alpha-methylene gamma-butyrolactone +  
amlexanox  
anisotropine methylbromide 
balsalazide +   
balsalazide disodium 
beta-cyfluthrin 
beta-cypermethrin 
bitertanol  
carbetocin 
carboprost 
carboprost tromethamine 
cetraxate 
cimetidine +   
cimetidine hydrochloride 
cisapride  
cyproconazole  
diclocymet 
egualen 
egualen sodium 
ergometrine +  
ergometrine maleate 
esomeprazole +   
esomeprazole magnesium 
eupatilin  
famotidine +   
fenoxanil 
fluprostenol +   
golgicide A 
hapten OTAb 
hapten OTAd 
hapten OTAe 
hapten OTAf 
homatropine methylbromide 
hypoglycin A 
hypoglycin B 
indaziflam 
iprovalicarb 
isopyrazam 
lansoprazole  
methotrexate  
mifepristone  
misoprostol  
A diastereoisomeric mixture composed of approximately equal amounts of a double racemate of four of the sixteen possible diastereoisomers of methyl (13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate that is racemic prostaglandin E1 which is lacking the hydroxy group at position 15, but which has an additional hydroxy group at position 16. It is a synthetic prostaglandin E1 analogue, used in the treatment of gastric and duodenal ulcers. A weak abortifacient, it is also used for cervical ripening prior to surgical termination of pregnancy. The (11R,16S)-diastereoisomer is the pharmacologically active form.
nadolol  
nizatidine  
omeprazole +   
oxmetidine 
oxytocin  
pantoprazole  
pantoprazole sodium 
pibutidine 
pibutidine hydrochloride 
pirenzepine +   
plaunotol  
proglumide +  
prostaglandin E2 +   
prostaglandin E2(1-) +  
pyrisoxazole 
rabeprazole  
ractopamine  
ranitidine +   
sedaxane 
sennoside 
succinic acid +   
sulfoxaflor  
teprenone  
tiquizium +   
tiquizium bromide  
tridihexethyl +  
trilostane  
valifenalate 
vedaprofen 
Yosprala 
zeta-cypermethrin 

Synonyms
Related Synonyms: (+-)-methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate ;   (11-alpha,13E)-(+-)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester ;   Arthrotec ;   Cytotec ;   Methyl (+-)-11-alpha,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate ;   misoprostolum
Alternate IDs: CHEBI:6952
Xrefs: CAS:59122-46-2 "ChemIDplus" ;   CAS:59122-46-2 "KEGG DRUG" ;   DrugBank:DB00929 ;   KEGG:D00419
Xref Mesh: MESH:D016595
Xrefs: PMID:10945193 "Europe PMC" ;   PMID:10949752 "Europe PMC" ;   PMID:11136959 "Europe PMC" ;   PMID:1417145 "Europe PMC" ;   PMID:18690850 "Europe PMC" ;   PMID:19740175 "Europe PMC" ;   PMID:2109814 "Europe PMC" ;   PMID:3080288 "Europe PMC" ;   Patent:BE827127 ;   Patent:US3965143 ;   Reaxys:4155643 "Reaxys" ;   Wikipedia:Misoprostol

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.