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Term:
Parent Terms Term With Siblings Child Terms
(+)-calanolide A 
(+)-pronuciferine 
(+)-schisandrin B  
(-)-calanolide B 
(16R)-deshydroxymethyl-stemmadenine 
(16S)-deshydroxymethyl-stemmadenine 
(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol 
(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride  
(1S,2S,3R,5S)-3,5-diaminocyclohexane-1,2-diol 
(1S,7R,8R,14S)-15,17-diazatetracyclo[12.2.2.1(3,7).1(8,12)]icosa-3(20),12(19)-diene-6,9-dione 
(4aR,10bS)-noroxomaritidine 
(4aS,10bR)-noroxomaritidine 
(methylsulfanyl)acetaldehyde +  
(methylsulfanyl)acetaldehyde oxime 
(methylthio)acetic acid 
(S)-carbinoxamine maleate 
(S)-corytuberine +   
(S)-glaucine +   
(S)-scoulerine +  
(S)-tetrahydrocolumbamine 
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one 
1,6:5,9:8,12:11,16-tetraanhydro-2,3,4,10,13,14-hexadeoxy-D-glycero-D-allo-D-gulo-heptadeca-2,13-dienitol 
1-(methylsulfanyl)acetaldoxime +   
1-(methylthio)ribulose 5-phosphate 
1-aci-nitro-omega-(methylsulfanyl)alkane 
1-azakenpaullone 
1-hydroxycrisamicin A 
1-isomangostin 
1-isothiocyanato-6-(methylsulfanyl)hexane 
1-methoxycanthinone 
1-methylthio-D-xylulose 5-phosphate(2-) 
10-hydroxycanthin-6-one 
12-epi-fischerindole G 
12-epi-fischerindole U 
12-epi-hapalindole U 
13-(2-methylcrotonoyloxy)lupanine 
13-hydroxylupanine 
15alpha-stemmadenine 
15beta-stemmadenine 
2,3,8,9-tetramethoxy-13-methyl-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene +  
2,3,8,9-tetramethoxy-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene +  
2,3,9,10-tetrahydroxyberbine 
2,6-diaminotoluene  
2,9-diamino-5,7-bis(trimethylsilyl)benzo[a]pyrimido[2,1,6-cd]pyrrolizine-3,4,8-tricarbonitrile 
2-(omega-methylthio)alkylmaleic acid +  
2-(omega-methylthio)alkylmalic acid +  
2-\{[(2E)-3-iodoprop-2-en-1-yl](propyl)amino\}tetralin-7-ol 
2-\{[(2E)-3-iodoprop-2-en-1-yl](propyl)amino\}tetralin-7-ol maleate 
2-chloro-1,4-phenylenediamine 
2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate 
2-methyl-1,4-phenylenediamine  
2-methyl-2-(methylsulfanyl)propanal oxime +   
2-methylthio-1,3-benzothiazole 
2-S-cysteinyl-DOPA 
2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one 
3-(4-tert-butylamino-6-methylthiol-s-triazin-2-ylamino)propionaldehyde 
3-(methylsulfanyl)propanal oxime 
3-(omega-methylthio)alkylmalic acid +  
3-[(6aR,9R)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea 
3-[(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea 
3-aza-A-homocholest-4a-en-4-one 
3-methylthioaspartic acid +  
3-methylthiopropanol +  
3-methylthiopropyl acetate 
4'-demethylepipodophyllotoxin +   
4'-demethylpodophyllotoxin 
4-(methylsulfanyl)butanal oxime 
4-Methylthiobutylthiohydroximate 
5,6-diaminouracil 
5,6-didehydrosparteine 
5-(methylsulfanyl)pentanal oxime +  
5-bromo-3-pyridinecarboxylic acid (10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinoline-9-yl)methyl ester 
5-bromo-3-pyridinecarboxylic acid [(6aS,9R,10aS)-10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinoline-9-yl]methyl ester 
5-chloro-2-methyl-2,3,3a,12b-tetrahydrodibenzo[2,3:6,7]oxepino[4,5-c]pyrrole +  
6-(methylthio)hexanonitrile oxide 
6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene +   
6-methyl-12-indolo[1,2-c]quinazolinamine 
6-O-methyl-2-deprenylrheediaxanthone B 
6-oxo-1,6-dihydrodibenzo[cd,g]indazole-3-sulfonic acid 
7-(methylthio)heptanonitrile oxide 
7-demethylmitomycin A 
7-demethylmitomycin B 
8,5'-cyclo-2'-deoxyadenosine  
8,5'-cyclo-2'-deoxyadenosine monophosphate 
8,5'-cyclo-2'-deoxyguanosine 
8,5'-cyclo-2'-deoxyguanosine monophosphate 
8-(methylthio)octylisothiocyanate 
8-amino-2,12-dihydroxy-4a,9-dihydro[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one 2-oxide 
8-cyclohexyl-2,3,3a,4,5,6-hexahydropyrazino[3,2,1-jk]carbazole +  
9(11)-dehydroaxinysterol 
9-[(methylthio)nonyl]thiohydroximic acid 
9-deoxy-hymatoxin A 
9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE 
9-hydroxycanthin-6-one  
9-hydroxyellipticine  
9-methoxycanthin-6-one 
abacopterin A 
abacopterin B 
abacopterin C 
abacopterin D 
acronidine 
acroptilin 
afidopyropen 
alangiside 
alectinib  
alizarin blue 
allocryptopine  
alpha-nimolactone 
alpha-peltatin +  
alsterpaullone  
amantadine  
amantadine hydrochloride 
amantadine sulfate 
amaryllisine 
ambiguine H 
amifostine  
ampelopsin B 
ananolignan B 
ananolignan C 
ananolignan D 
ananolignan E 
ananolignan F 
ananolignan G 
ananolignan H 
ananolignan I 
ananolignan J 
ananolignan K 
ananolignan L 
ananolignan M 
ananolignan N 
anthrafuran +  
anthrapyrazole +   
apomorphine +   
arborescin 
arglabin +  
aristolochic acid +   
aristoloterpenate-I 
arisugacin A 
arisugacin B 
arisugacin C 
arisugacin D 
artoindonesianin E1 
arugosin C 
asperaculin A 
asperlicin 
asperlicin C 
Aspirochlorine 
ATTO 610-2 +  
ATTO 610-2(1+) +  
ATTO 635-2 +  
ATTO 635-2(1+) +  
azadirachtin A  
azatetracycloalkane +   
azirinopyrroloindole +   
azocarmine B free acid 
azocarmine G free acid 
bauhinoxepin A 
benserazide  
benserazide hydrochloride 
benzathine 
benzatropine +   
benzatropine mesylate 
benzopyrrolopteridine +  
berbine +  
berkeleydione 
berkeleyone B 
beta-erythroidine +   
beta-nimolactone 
beta-obscurine 
beta-peltatin 
BF 4 
BF 5 
BF 6 
bianfugenine 
bikaverin 
biperiden +   
biperiden hydrochloride 
botryosphaerin H 
brazilein  
brazilin  
bromocriptine +   
bromocriptine methanesulfonate 
bryostatin 1  
bryostatin 2  
cabergoline  
Camoensine 
canthin-6-one +   
carbidopa  
carbidopa (anhydrous) +   
carbinoxamine +   
carbinoxamine maleate +  
caribenol A 
cariprazine  
cariprazine hydrochloride 
carmoxirole  
carmoxirole hydrochloride 
catiguanin A 
catiguanin B 
chaetominine 
chaetomugilin A 
chaetomugilin D  
chaetoviridin B 
chaetoviridin D 
chaetoviridin I 
CHIR 99021  
columbamine +   
coriatin 
cratoxyarborenone D 
cresyl violet +  
cryptolepine  
cycloinumakiol 
cyclomulberrin +  
cycrimine +  
cycrimine hydrochloride +  
cystodytin D +  
cystodytin E +  
cystodytin F 
cystodytin G 
cystodytin H 
cystodytin I 
deoxyherqueinone 
diamino-1,3,5-triazine +   
dibenzonaphthyridine +  
dihydro-beta-erythroidine  
dihydroergotamine +   
dihydroprecondylocarpine acetate 
diphenhydramine +   
diphenhydramine hydrochloride 
diplotasin 
dopamine receptor D1 agonist +   
dorsilurin K 
dregamine 
drymaritin 
ehretianone 
ekatetrone 
elbasvir +  
ellagic acid +   
ellipticine  
entacapone +   
epi-cochlioquinone A 
ergoline +   
ergometrine +  
ethyl nile blue(1+) +  
etoposide  
eucalyptal A 
eucalyptal B 
eucalyptal C 
fenoldopam  
flavalin A 
fleephilone 
furonaphthodioxole +   
galanthamine  
gamma-thiomethyl glutamate 
garciniaxanthone F 
garciniaxanthone G 
geissoschizine +  
geissospermine 
gentamycin 2''-phosphate 
glandicoline B +  
glionitrin A 
gliotoxin  
guignardone N 
haematoxylin +  
hapalindole G 
hapalindole H 
hapalindole U 
hematein 
hexahomomethionine +  
hydrabamine +  
indolobenzazepine +   
integrastatin A 
integrastatin B 
interiotherin C 
intermediate I 
isoquinolinonaphthyridine +  
isosojagol 
isotanshinone IIB 
Jeffamine ED-2001 
JSH-23 
L-beta-homomethionine 
L-dopa +  
L-polyhomomethionine +  
lespedezol D1 
liphagal 
lissoclibadin 1 
lisuride +   
longipedumin A 
lorlatinib 
lucensimycin E 
lycojapodine A 
lysergic acid diethylamide  
M3 
maytansine +  
meleagrine 
memantine  
memantine hydrochloride 
mertansine 
mesulergine  
metergoline  
methyl (1S,2S,16E)-16-ethylidene-2-formyl-4,14-diazatetracyclo[12.2.2.0(3,11).0(5,10)]octadeca-3(11),5(10),6,8-tetraene-2-carboxylate 
methylthio-1,3,5-triazine +   
metixene +   
minabeolide 1 
minabeolide 2 
minabeolide 4 
minabeolide 5 
minabeolide 8 
minaprine +  
mitchellene A 
mitchellene B 
mitchellene C 
mollicellin B 
mollicellin F 
mollicellin M 
mollicellin N 
mycocyclosin 
N,N-dihydroxy-L-polyhomomethionine +  
N,N-dimethyl-1,4-phenylenediamine 
N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl)methyl]carbamic acid (phenylmethyl) ester 
N-\{[2-(3-chloro-4-fluorophenyl)hydrazino]carbonyl\}-3,5-bis(methylthio)isothiazole-4-carboxamide 
N-acetylmethionine +  
N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol  
N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepinium-7,8-diol 
N-hydroxy-L-polyhomomethionine +  
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol  
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-substituted diamine +   
nagilactone F 
naphthochromene +  
naphthoisochromene +  
neotriptophenolide 
nepalensinol F 
neticonazole  
Nicergoline 
nigakihemiacetal A 
nigrasin G 
nile red 
O-acetyl-15alpha-stemmadenine 
omega-(methylsulfanyl)-(E)-alkanal oxime +  
omega-(methylthio)-2-oxocarboxylic acid +   
ophioglonin +  
oriciacridone C 
oriciacridone F 
orphenadrine +   
orphenadrine hydrochloride 
ossamycin 
oxaline 
oxatetracycloalkane +   
oxazine-170 
oxazine-170(1+) +  
palmatine +   
pancixanthone B 
PD158780 
pergolide  
A diamine that is ergoline in which the beta-hydrogen at position 8 is replaced by a (methylthio)methyl group and the hydrogen attached to the piperidine nitrogen (position 6) is replaced by a propyl group. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it is used as the mesylate salt in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction.
pergolide mesylate 
picropodophyllotoxin  
piperlactam S 
podophyllotoxin +   
polyneuridine aldehyde 
pramipexole  
pramipexole hydrochloride 
pramipexole hydrochloride anhydrous +  
preaustinoid A1 
precondylocarpine acetate 
precursor Z 
precursor Z hydrate 
prenyl-FMN 
prenyl-FMNH2 
pridinol  
primary diamine +   
procyclidine +   
profenamine +   
profenamine hydrochloride 
propylenediamine +  
protubonine A +  
protubonine B 
psorospermin  
PX-866  
pyranoxanthene +  
pyranoxanthones +   
pyrazinopyridoindole +   
pyridocarbazole +  
pyridophenoxazine +  
pyripyropene A 
pyripyropene I 
pyripyropene J 
pyripyropene K 
pyripyropene L 
quinpirole  
rifamycin B 
rifamycin CGP 4832 
rifamycin SV +   
rifamycin SV hemiaminal 
ropinirole  
S-[9-(methylthio)nonylhydroximoyl]-L-cysteine 
S-methyl glutathione(1-) 
S-methyl-5-thio-D-ribofuranose +  
S-methyl-L-ergothioneine 
S-methylglutathione  
sanggenol H 
saroglitazar 
SB 224289 
scutebarbatine F 
scutebarbatine G 
selegiline hydrochloride 
SN-38 carboxylic acid 
stephanthrine 
stepharanine 
stepharine 
strongylin A 
tabernaemontanine 
taiwanschirin D 
terretonin 
tetracyclic antidepressant +   
tetrahomomethionine +  
tetrahydropalmatine  
tolcapone  
TOP-53 
trichodermin 
trichodimerol 
trihomomethionine +  
triptonolide 
triptophenolide methyl ether 
Tryptanthrine  
varenicline  
verrucarin A  
vincaleukoblastine +   
vincristine  
vindesine +   
vinflunine 
vinorelbine +   
vobasine 
WR-1065  
xenovulene A 
yadanziolide T 
yadanziolide U 
yucalexin P8 

Synonyms
Exact Synonyms: (8beta)-8-[(methylsulfanyl)methyl]-6-propylergoline
Related Synonyms: Formula=C19H26N2S ;   InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 ;   InChIKey=YEHCICAEULNIGD-MZMPZRCHSA-N ;   SMILES=[H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])C[C@@H](CSC)CN2CCC ;   pergolida ;   pergolidum
Alternate IDs: CHEBI:8020
Xrefs: CAS:66104-22-1 ;   DrugBank:DB01186 ;   Drug_Central:2105 ;   HMDB:HMDB0015317 ;   KEGG:C07425 ;   KEGG:D08339 ;   LINCS:LSM-3352
Xref Mesh: MESH:D010479
Xrefs: PMID:11852289 ;   PMID:15180134 ;   PMID:16845152 ;   PMID:18071034 ;   PMID:2012117 ;   Patent:US4166182 ;   Reaxys:5091461 ;   Wikipedia:Pergolide
Cyclic Relationships: is_conjugate_base_of CHEBI:63706

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.