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A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has S configuration. It is used (generally as the monohydrochloride salt) to treat parasitic worm infections in pigs, sheep and cattle and was formerly used in humans as an adjuvant to chemotherapy for the treatment of various cancers. It is also widely used as an adulterant to coccaine.
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Synonyms
Exact Synonyms: (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
Related Synonyms: (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole ;   (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole ;   (-)-tetramisole ;   (S)-(-)-levamisole ;   (S)-(-)-tetramisole ;   (S)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole ;   Formula=C11H12N2S ;   InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1 ;   InChIKey=HLFSDGLLUJUHTE-SNVBAGLBSA-N ;   Ketrax ;   Lepuron ;   Levomysol ;   Levovermax ;   SMILES=C1CN2C[C@@H](N=C2S1)c1ccccc1 ;   Totalon ;   Wormicid ;   levamisol ;   levamisolum
Xrefs: CAS:14769-73-4 "ChemIDplus" ;   CAS:14769-73-4 "KEGG COMPOUND" ;   DrugBank:DB00848 ;   Drug_Central:1561 "DrugCentral" ;   HMDB:HMDB0014986 ;   KEGG:C07070 ;   KEGG:D08114 ;   LINCS:LSM-6655
Xref Mesh: MESH:D007978
Xrefs: PMID:10701095 "Europe PMC" ;   PMID:12232676 "Europe PMC" ;   PMID:12749943 "Europe PMC" ;   PMID:15109274 "Europe PMC" ;   PMID:1618599 "Europe PMC" ;   PMID:17608969 "Europe PMC" ;   PMID:189006 "Europe PMC" ;   PMID:2050823 "Europe PMC" ;   PMID:22337783 "Europe PMC" ;   PMID:22607692 "Europe PMC" ;   PMID:23041983 "Europe PMC" ;   PMID:23152411 "Europe PMC" ;   PMID:23543977 "Europe PMC" ;   PMID:23577329 "Europe PMC" ;   PMID:23649929 "Europe PMC" ;   PMID:23921349 "Europe PMC" ;   PMID:24365689 "Europe PMC" ;   PMID:24440755 "Europe PMC" ;   PMID:365327 "Europe PMC" ;   PMID:366135 "Europe PMC" ;   PMID:366137 "Europe PMC" ;   PMID:669135 "Europe PMC" ;   PMID:6995092 "Europe PMC" ;   PMID:6995094 "Europe PMC" ;   PMID:7051554 "Europe PMC" ;   PMID:827785 "Europe PMC" ;   Patent:US3274209 ;   Patent:US3565907 ;   Patent:US3579530 ;   Reaxys:4233256 "Reaxys" ;   VSDB:1798 ;   Wikipedia:Levamisole
Cyclic Relationships: is_enantiomer_of CHEBI:77282

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.