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Ontology Browser

Term:
guanosine 5'-[beta,gamma-imido]triphosphate (CHEBI:78408)
Annotations: Rat: (6) Mouse: (6) Human: (6) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
2'-deoxyguanosine 5'-[beta,gamma-methylene]triphosphate 
2-(ethoxymethyl)-4-(4-fluorophenyl)-3-[2-(2-hydroxyphenoxy)pyrimidin-4-yl]isoxazol-5(2H)-one 
adenosine 5'-[alpha,beta-methylene]triphosphate 
adenosine 5'-[beta,gamma-methylene]triphosphate 
adenosine 5'-[gamma-thio]triphosphate  
cangrelor  
gamma-aminooctyl-GTP 
guanosine 5'-[beta,gamma-imido]triphosphate  
A nucleoside triphosphate analogue that is GTP in which the oxygen atom bridging the beta- to the gamma- phosphate is replaced by a nitrogen atom A non-hydrolyzable analog of GTP, it binds tightly to G-protein in the presence of Mg(2+).
guanosine 5'-[beta,gamma-methylene]triphosphate 
guanosine 5'-[gamma-thio]triphosphate  

Synonyms
Exact Synonyms: 5'-O-(hydroxy{[hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl)guanosine
Related Synonyms: 5'-Guanylic acid, monoanhydride with imidodiphosphoric acid ;   5'-guanylylimidodiphosphate ;   Formula=C10H17N6O13P3 ;   GMP-Pnp ;   Gpp(NH)p ;   Guanylyl imidodiphosphate ;   InChI=1S/C10H17N6O13P3/c11-10-13-7-4(8(19)14-10)12-2-16(7)9-6(18)5(17)3(28-9)1-27-32(25,26)29-31(23,24)15-30(20,21)22/h2-3,5-6,9,17-18H,1H2,(H,25,26)(H3,11,13,14,19)(H4,15,20,21,22,23,24)/t3-,5-,6-,9-/m1/s1 ;   InChIKey=UQABYHGXWYXDTK-UUOKFMHZSA-N ;   SMILES=Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)NP(O)(O)=O)[C@@H](O)[C@H]1O
Alternate IDs: CHEBI:42862
Xrefs: CAS:34273-04-6 "ChemIDplus"
Xref Mesh: MESH:D006165
Xrefs: PDBeChem:GNP ;   PMID:1547891 "Europe PMC" ;   PMID:166994 "Europe PMC" ;   PMID:1672318 "Europe PMC" ;   PMID:188052 "Europe PMC" ;   PMID:3103629 "Europe PMC" ;   PMID:3159604 "Europe PMC" ;   PMID:4607368 "Europe PMC" ;   Reaxys:1201190 "Reaxys" ;   Wikipedia:5'-Guanylyl_imidodiphosphate
Cyclic Relationships: is_conjugate_acid_of CHEBI:78409

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.