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Term:
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
Annotations: Rat: (682) Mouse: (698) Human: (695) Chinchilla: (0) Bonobo: (0) Dog: (5) Squirrel: (0) Pig: (12)
Parent Terms Term With Siblings Child Terms
(+)-makassaric acid 
(+)-subersic acid 
1,4-diamino-2,3-dicyano-1,4-bis(phenylthio)butadiene 
1,8-dihydroxy-4-nitroxanthen-9-one 
2-(\{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl\}amino)benzamide 
aminopurvalanol 
Aurora kinase inhibitor +   
CMB4563 
CZC8004 
DMH1 
EC 2.7.10.* (protein-tyrosine kinase) inhibitor +   
EC 2.7.11.* (protein-serine/threonine kinase) inhibitor +   
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor +   
EC 2.7.11.10 (IkappaB kinase) inhibitor +   
EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor +   
EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor +   
EC 2.7.11.13 (protein kinase C) inhibitor +   
EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor +   
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor +   
EC 2.7.11.20 (elongation factor 2 kinase) inhibitor +  
EC 2.7.11.21 (polo kinase) inhibitor +  
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor +   
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor +   
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
EC 2.7.11.26 (tau-protein kinase) inhibitor +   
EC 2.7.11.30 (receptor protein serine/threonine kinase) inhibitor +   
EC 2.7.11.31 \{[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase\} inhibitor +   
epidermal growth factor receptor antagonist +   
erlotinib +   
erlotinib hydrochloride  
gamma-mangostin  
miltefosine  
mTOR inhibitor +   
pelitinib +  
piceatannol +  
purvalanol B 
quercetin +   
Ro 320-1195 +  
salt-inducible kinase 2 inhibitor +  
sangivamycin 
tyrosine kinase inhibitor +   
XMD8-92 

Synonyms
Related Synonyms: ATP:protein phosphotransferase (MAPKK-activated) inhibitor ;   ATP:protein phosphotransferase (MAPKK-activated) inhibitors ;   Dp38 inhibitor ;   Dp38 inhibitors ;   EC 2.7.11.24 (mitogen-activated protein kinase) inhibitors ;   EC 2.7.11.24 inhibitor ;   EC 2.7.11.24 inhibitors ;   ERK inhibitor ;   ERK inhibitors ;   ERK1 inhibitor ;   ERK1 inhibitors ;   ERK2 inhibitor ;   ERK2 inhibitors ;   JNK inhibitor ;   JNK inhibitors ;   JNK3alpha1 inhibitor ;   JNK3alpha1 inhibitors ;   LeMPK3 inhibitor ;   LeMPK3 inhibitors ;   MAP kinase inhibitor ;   MAP kinase inhibitors ;   MAP-2 kinase inhibitor ;   MAP-2 kinase inhibitors ;   MAPK inhibitor ;   MAPK inhibitors ;   MBP kinase I inhibitor ;   MBP kinase I inhibitors ;   MBP kinase II inhibitor ;   MBP kinase II inhibitors ;   MEK inhibitor ;   MEK inhibitors ;   PMK-1 inhibitor ;   PMK-1 inhibitors ;   PMK-2 inhibitor ;   PMK-2 inhibitors ;   PMK-3 inhibitor ;   PMK-3 inhibitors ;   SAPK inhibitor ;   SAPK inhibitors ;   STK26 inhibitor ;   STK26 inhibitors ;   c-Jun N-terminal kinase inhibitor ;   c-Jun N-terminal kinase inhibitors ;   extracellular signal-regulated kinase inhibitor ;   extracellular signal-regulated kinase inhibitors ;   microtubule-associated protein 2 kinase inhibitor ;   microtubule-associated protein 2 kinase inhibitors ;   microtubule-associated protein kinase inhibitor ;   microtubule-associated protein kinase inhibitors ;   mitogen-activated protein kinase inhibitor ;   mitogen-activated protein kinase inhibitors ;   myelin basic protein kinase inhibitor ;   myelin basic protein kinase inhibitors ;   p38-2 inhibitor ;   p38-2 inhibitors ;   p38delta inhibitor ;   p38delta inhibitors ;   p42 mitogen-activated protein kinase inhibitor ;   p42 mitogen-activated protein kinase inhibitors ;   p42(mapk) inhibitor ;   p42(mapk) inhibitors ;   p44mpk inhibitor ;   p44mpk inhibitors ;   pp42 inhibitor ;   pp42 inhibitors ;   pp44(mapk) inhibitor ;   pp44(mapk) inhibitors ;   stress-activated protein kinase inhibitor ;   stress-activated protein kinase inhibitors
Alternate IDs: CHEBI:75997
Xrefs: Wikipedia:MEK_inhibitor ;   Wikipedia:Mitogen-activated_protein_kinase

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.