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Term:
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(4R)-limonene hydroperoxide +  
(5R)-5-methylimidazolidine-2,4-dione 
(5S)-5-methylimidazolidine-2,4-dione 
(5S,5aR,8aS,8bR)-7-tert-butyl-5-(4-methoxyphenyl)-8b-methyl-2-(3-methylphenyl)-5a,8a-dihydro-5H-pyrrolo[1,2]pyrrolo[4,5-a]imidazole-1,3,6,8-tetrone 
(S)-nicotine +   
(S)-thalidomide +   
1,1-dimethylhydrazine 
1-(5-hydroxy-2-oxo-2,3-dihydroimidazol-4-yl)urea 
1-(hydroxymethyl)-5,5-dimethylhydantoin 
1-[(5-nitro-2-furanyl)methylideneamino]imidazolidine-2,4-dione 
2-(2',5'-dioxo-1'-spiro[3,4-dihydro-2H-1-benzopyran-4,4'-imidazolidine]yl)-N-[4-[ethyl(propan-2-yl)amino]phenyl]acetamide 
2-(2,5-dioxo-4,4-dipropyl-1-imidazolidinyl)-N-(3-methoxyphenyl)acetamide 
2-(2,5-dioxo-4-imidazolidinyl)-N-(1-naphthalenyl)acetamide 
2-(2-methoxyethoxy)ethanol 
2-(4-butyl-4-methyl-2,5-dioxo-1-imidazolidinyl)-N-[4-(4-morpholinylsulfonyl)phenyl]acetamide 
2-[4-(2-furanylmethylidene)-2,5-dioxo-1-imidazolidinyl]-N-(4-methylphenyl)acetamide 
2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxo-1-imidazolidinyl]-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]acetamide 
2-[4-[(1-ethyl-2,5-dimethyl-3-pyrrolyl)methylidene]-2,5-dioxo-1-imidazolidinyl]-N-(3-methylphenyl)acetamide 
2-[4-[(3-ethoxy-4-hydroxyphenyl)methylidene]-2,5-dioxo-1-imidazolidinyl]-N-(3-methylphenyl)acetamide 
2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxo-1-imidazolidinyl]acetic acid ethyl ester 
2-[[2-(4-ethyl-4-methyl-2,5-dioxo-1-imidazolidinyl)-1-oxoethyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
2-amino-6-hydroxyaminopurine 
2-ethoxyethanol +   
3,3',4',5-tetrachlorosalicylanilide  
3,6,8-Trimethylallantoin 
3-(\{(5R)-3-[3-(1H-imidazol-1-yl)propyl]-5-methyl-5-naphthalen-1-yl-2,4-dioxoimidazolidin-1-yl\}methyl)benzonitrile 
3-[(2-fluorophenyl)methyl]-5-(1H-indol-3-ylmethylidene)imidazolidine-2,4-dione 
3-[(2-fluorophenyl)methyl]-5-[(5-methyl-2-furanyl)methylidene]imidazolidine-2,4-dione 
3-[(4S)-2,5-dioxoimidazolidin-4-yl]propanoic acid 
3-[2-[4-(4-chlorophenyl)sulfonyl-1-piperazinyl]-2-oxoethyl]-5-(2-methylpropyl)imidazolidine-2,4-dione 
3-[2-[[1-(3-chlorophenyl)-2,5-dioxo-4-imidazolidinylidene]methyl]-1-pyrrolyl]benzoic acid 
3-[2-hydroxy-3-(4-morpholinyl)propyl]-5,5-dimethylimidazolidine-2,4-dione 
4',5-dihydroxydiclofenac 
4-[(2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)methyl]benzoic acid methyl ester 
4-[2-[(2,5-dioxo-1-phenyl-4-imidazolidinylidene)methyl]-1-pyrrolyl]benzoic acid 
4-[5-[[1-[(2-chlorophenyl)methyl]-2,5-dioxo-4-imidazolidinylidene]methyl]-2-furanyl]-3-methylbenzoic acid 
4-[[2-ethoxy-4-[(1-ethyl-2,5-dioxo-4-imidazolidinylidene)methyl]-6-prop-2-enylphenoxy]methyl]benzoic acid 
4-hydroperoxycyclophosphamide  
4-hydroxyphenytoin  
5,5-diethylbarbituric acid  
5,7-dihydroxy-4'-methoxyflavone +   
5-(2-furanylmethylidene)imidazolidine-2,4-dione 
5-(4-hydroxybutyl)hydantoin 
5-(N,N-hexamethylene)amiloride  
5-(N-methyl-N-propyl)amiloride 
5-[(1-ethyl-2,5-dimethyl-3-pyrrolyl)methylidene]-3-phenylimidazolidine-2,4-dione 
5-[(2,4,5-trihydroxyphenyl)methyl]imidazolidine-2,4-dione 
5-[[2,5-dimethyl-1-(3-pyridinyl)-3-pyrrolyl]methylidene]-3-phenylimidazolidine-2,4-dione 
5-chlorospiro[indole-3,2'-[1,3]oxathiolan]-2(1H)-one 
5-guanidinohydantoin 
5-methyl-3-[2-(4-morpholinyl)-2-oxoethyl]-5-phenylimidazolidine-2,4-dione 
5-methylimidazolidine-2,4-dione 
6-aminonicotinamide  
7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid +   
abacavir +   
acetaldehyde +   
acetazolamide +   
acetylsalicylic acid +   
adinazolam  
alclofenac  
alcuronium bromide 
allantoin +   
alpha-asarone 
alprazolam  
amiloride +   
amiloride hydrochloride +  
amiloride hydrochloride dihydrate 
amino(diphenylhydantoin) valeric acid 
aminoglutethimide +   
ammodendrine 
amodiaquine +   
anabasine +   
arotinoid acid  
azetidine-2-carboxylic acid +  
Azimilide  
aztreonam +   
azumolene 
benzo[d]isothiazol-3-one  
benzoic acid +   
benzylpenicillin +   
BMS-453 
brivaracetam 
budesonide  
bupivacaine  
busulfan  
calcipotriol +   
carbamazepine +   
carbapenem MM22383 
carnosine +   
cefaclor  
cefixime  
cefotaxime  
ceftazidime +   
ceftriaxone  
cefuroxime  
cephalosporin +   
CGP 78608 
CGP 78608 hydrochloride 
chlorambucil  
cinolazepam 
clobazam  
clodantoin 
clonazepam  
clorazepic acid 
co-trimoxazole  
cocaine  
codeine +   
cortisol +   
cortisol 17-butyrate 
cyclophosphamide +   
D-5-monosubstituted hydantoin +  
D-penicillamine +   
dantrolene  
desipramine +   
desipramine hydrochloride 
diaveridine 
diazepam +   
diazolidinylurea 
diazoxide  
dibutyl phthalate  
diclofenac +   
didesethylflurazepam 
diethyl phthalate  
diisobutyl phthalate  
dinocap  
diphenylcyclopropenone  
dipotassium clorazepate 
disodium cromoglycate  
encainide +  
eslicarbazepine acetate 
estazolam  
ethanol +   
ethosuximide +   
ethotoin +   
ethyl methanesulfonate  
ethylisopropylamiloride  
Evans blue 
Evans blue free acid 
ezogabine  
felbamate  
fenoprofen  
fenticlor 
flubendazole  
flumioxazin 
flumipropyn 
fluoxetine  
flurazepam +   
Fosphenytoin 
furagin 
gabapentin +   
gabapentin enacarbil 
gallamine 
glutaurine 
glutaurine zwitterion 
glutaurine(1-) 
hadacidin 
hentriacontan-16-one 
hispidulin  
hydantoin +   
hydantoin-5-propionic acid 
hydroxyurea  
ibuprofen +   
icajine  
Idanpramine 
iprodione  
isoniazide +   
isotretinoin  
ketoprofen  
L-5-carboxymethylhydantoin 
L-5-monosubstituted hydantoin +  
L-cycloserine +  
L-lysine +   
lamotrigine  
levetiracetam  
licarbazepine +  
lidocaine +   
magnesium sulfate +   
malachite green 
meclofenamic acid  
melatonin +   
melphalan  
mephenytoin 
mephobarbital  
mepivacaine +   
meropenem +   
methohexital  
metiazinic acid 
mevinolinic acid 
midazolam +   
midazolam hydrochloride 
morphine +   
N(6)-hydroxyadenine 
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-methyl-2,5-dioxo-4-(2-phenylethyl)-1-imidazolidinyl]acetamide 
N-(3-cyanophenyl)-2-(4-ethyl-2,5-dioxo-4-phenyl-1-imidazolidinyl)acetamide 
N-(3-methylphenyl)-2-[4-[(5-methyl-2-thiophenyl)methylidene]-2,5-dioxo-1-imidazolidinyl]acetamide 
N-(4-ethoxyphenyl)-2-[4-[2-(methylthio)ethyl]-2,5-dioxo-1-imidazolidinyl]acetamide 
N-(4-methylphenyl)-2-[4-[(5-methyl-2-thiophenyl)methylidene]-2,5-dioxo-1-imidazolidinyl]acetamide 
N-[3-(1-azepanylsulfonyl)phenyl]-2-[4-(1H-indol-3-ylmethyl)-2,5-dioxo-1-imidazolidinyl]acetamide 
N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-[4-methyl-4-(4-methylphenyl)-2,5-dioxo-1-imidazolidinyl]acetamide 
N-arachidonoylserotonin 
N-methyl-N-nitrosourea  
N-methylhydantoin 
naproxen +   
nicotine +   
nifurfoline 
nifurtoinol 
nimetazepam  
Nirvanol 
nitrazepam +   
nitrofurantoin  
nordazepam  
ochratoxin A +   
omeprazole +   
otophylloside B 
oxcarbazepine  
oxybuprocaine +   
palmitoyl ethanolamide  
parthenolide +   
perampanel +  
perampanel hydrate 
phenobarbital +   
phenytoin  
A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5.
phethenylate 
pholcodine 
piroctone olamine 
pregabalin  
prilocaine +  
primidone  
procainamide +   
procaine  
propofol  
pyrrolidine dithiocarbamate  
quinidine +   
ranitidine +   
ranitidine hydrochloride 
ranolazine  
RO4927350 
rocuronium +   
saxitoxin +   
sodium benzoate +   
sodium meclofenamate monohydrate 
sodium selenate 
solasodine  
solasodine(1+) +  
soraphen A 
spiroiminodihydantoin 
succinylcholine +   
sulfachloropyridazine 
sulfadiazine  
sulfadimethoxine  
sulfamerazine  
sulfamethazine  
sulfamethizole 
sulfamethoxazole +   
sulfamethoxypyridazine 
sulfamoxole 
sulfanilamide +   
sulfapyridine  
sulfasalazine  
sulfathiazole +  
sulfisoxazole +   
suprofen  
tazarotene  
tazarotenic acid +   
thalidomide +   
thimerosal  
thiopental  
tiagabine  
tiagabine hydrochloride 
tiaprofenic acid  
tocainide 
topiramate  
triamterene 
triclosan  
trimethoprim +   
trioctanoin 
troglitazone  
tubocurarine  
valproate semisodium 
valproic acid +   
valpromide  
vanillin +   
vecuronium +   
vigabatrin  
vismodegib  
voltage-gated sodium channel blocker +   
zaleplon  
zofenopril 
zofenopril calcium 
zofenoprilat 
zofenoprilat arginine 
zonisamide  

Synonyms
Related Synonyms: 5,5-Diphenyl-imidazolidine-2,4-dione ;   5,5-diphenylimidazolidine-2,4-dione ;   5,5-diphenyltetrahydro-1H-2,4-imidazoledione ;   DILANTIN ;   Formula=C15H12N2O2 ;   InChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19) ;   InChIKey=CXOFVDLJLONNDW-UHFFFAOYSA-N ;   PHENTYTOIN ;   SMILES=O=C1NC(=O)C(N1)(c1ccccc1)c1ccccc1 ;   fenitoina ;   phenytoine ;   phenytoinum
Alternate IDs: CHEBI:100921
Xrefs: Beilstein:384532 "Beilstein" ;   CAS:57-41-0 "ChemIDplus" ;   CAS:57-41-0 "KEGG COMPOUND" ;   DrugBank:DB00252 ;   Drug_Central:2152 "DrugCentral" ;   HMDB:HMDB0014397 ;   KEGG:C07443 ;   KEGG:D00512 ;   LINCS:LSM-5663
Xref Mesh: MESH:D010672
Xrefs: PMID:10698828 "Europe PMC" ;   PMID:12952753 "Europe PMC" ;   PMID:15246836 "Europe PMC" ;   PMID:15744730 "Europe PMC" ;   PMID:16303054 "Europe PMC" ;   PMID:7105825 "Europe PMC" ;   PMID:7602118 "Europe PMC" ;   PMID:9186244 "Europe PMC" ;   Patent:WO2012174723 ;   Reaxys:384532 "Reaxys" ;   Wikipedia:Phenytoin

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.