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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
(+)-calanolide A 
(-)-calanolide B 
(1R,4R,5R,8S)-8-hydroxy-4,8-dimethyl-2-oxabicyclo[3.3.1]nonan-3-one 
(1S,3R,7S,8S,8aR)-8-\{2-[(2S,4R)-4-hydroxy-1-\{[5-(hydroxymethyl)-6-methoxynaphthalen-2-yl]methyl\}-6-oxopiperidin-2-yl]ethyl\}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate 
(2S)-2-methylbutanoic acid [(1S,3R,7S,8S,8aS)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-2-oxanyl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] ester 
(2S)-2-methylbutanoic acid [(1S,7S,8S,8aR)-8-[2-[(2R,4S)-4-hydroxy-2-oxanyl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] ester 
(2S)-2-methylbutanoic acid [(1S,7S,8S,8aS)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-2-oxanyl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] ester 
(2S)-2-methylbutanoic acid [(7S,8S,8aR)-8-[2-[(2R)-4-hydroxy-6-oxo-2-oxanyl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] ester 
(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid +   
(3S)-3-[(2S,3S,4R)-3,4-dimethyltetrahydrofuran-2-yl]butyl laurate 
(3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-\{[(2Z)-2-methylbut-2-enoyl]oxy\}-7-(octanoyloxy)-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-4-yl 12-[(tert-butoxycarbonyl)amino]dodecanoate 
(4R,6R)-6-\{2-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl\}-4-hydroxyoxan-2-one 
(Z)-3,5-Hexadienyl butyrate 
1,2-campholide +  
1,2-diacetyltrichagmalin C 
1,3-Di-(octadec-9Z-enoyl)-1-cyano-2-methylene-propane-1,3-diol 
1,30-diacetyltrichagmalin F 
1-behenoylglycerol 
1-erucoylglycerol 
1-naphthyl tetradecanoate 
1-nervonoylglycerol 
1-tetracosanoylglycerol 
11Z-Octadecenylcarnitine 
12-(octadecanoyloxy)octadecanoic acid 
12-[(9Z)-hexadecenoyloxy]octadecanoic acid 
12-[(9Z)-octadecenoyloxy]octadecanoic acid 
12-hydroxyplatencinic acid methyl ester 
13-(octadecanoyloxy)octadecanoic acid 
13-[(9Z)-hexadecenoyloxy]octadecanoic acid 
13-[(9Z)-octadecenoyloxy]octadecanoic acid 
15-acetyltrichagmalin C 
15-acetyltrichagmalin E 
15-O-acetylbruceolide 
15-O-propionylbruceolide 
17alpha-hydroxywithanolide D 
2,2-dimethylbutanoic acid [(7S,8S)-8-[2-[(2R)-4-hydroxy-6-oxo-2-oxanyl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] ester 
2,2-dimethylbutanoic acid [8-[2-(4-hydroxy-6-oxo-2-oxanyl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] ester 
2,3-dihydro-3beta-methoxy withaferin A 
2,3-dihydro-3beta-O-sulfate withaferin A 
2,3-dihydrowithaferin A 
2-[(1E)-3,4-dihydroxypent-1-en-1-yl]-6-oxooxan-3-yl (2E)-2-methylbut-2-enoate 
2-cyano-4-(1-methyl-4-pyridinylidene)-2-butenoic acid ethyl ester 
2-hydroxy-17beta-estradiol +   
2-Methylpropyl 3-methylbutanoate 
2-phenylethyl pentanoate 
2-pyranones +   
20-hydroxytubocapsanolide A 
23-hydroxytubocapsanolide A 
3,15-di-O-acetylbruceolide 
3,15-di-O-propionylbruceolide 
3-(2-furanyl)-2-propenoic acid [2-[methyl-(phenylmethyl)amino]-2-oxoethyl] ester 
3-(3,5-dioxo-2H-1,2,4-triazin-6-yl)propanoic acid ethyl ester 
3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol hydrochloride 
3-\{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl\}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl hexadecanoate +   
3-acetyltrichorabdal C 
3-butyl-5-(4-morpholinylmethyl)-2-oxo-3-oxolanecarboxylic acid ethyl ester 
3-methylbutyl octanoate 
3-phenylpropanoic acid 2-(dimethylamino)ethyl ester 
30-acetyltrichagmalin F 
3alpha,6alpha-epoxy-4beta,5beta,27-trihydroxy-1-oxowitha-24-enolide 
3alpha-Acetoxymaoesin A, (rel)- 
3beta,13-dihydroxy-16-(hydroxymethylene)-13,17-seco-5alpha-androstan-17-oic acid, delta-lactone 
3beta-[(alpha-L-arabinopyranosyl)oxy]-20beta-hydroxyursan-28-oic acid delta-lactone 
3Z-hexenyl 2R-hydroxy-3-methylbutyrate 
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate  
4-(fluoromethyl)-4-hydroxy-2-oxanone 
4-Ethoxy-4-oxobutanoic acid 
4-hydroxy-4-methyl-2-oxanone 
4-hydroxymellein 
4-phenylbutyric acid  
5-(4'-hydroxyphenyl)-valeric acid-O-glucuronide 
5-[(9Z)-hexadecenoyloxy]octadecanoic acid 
5-[(9Z)-octadecenoyloxy]octadecanoic acid 
5-aminolevulinic acid +   
5-aminolevulinic acid hydrochloride 
5-valerolactone +  
6-(3-hexenyl)tetrahydro-2H-pyran-2-one 
6-pentyloxan-2-one 
7-deacetyl-17-epinimolicinol 
7-deacetyl-7-benzoylgedunin 
7-deacetylgedunin 
7-demethoxyegonol oleate 
7-demethoxylegonol-2-methylbutanoate 
8'-epi-cleomiscosin A 
8-acetoxyheterophyllisine 
9-(octadecanoyloxy)octadecanoic acid 
9-[(9Z)-hexadecenoyloxy]octadecanoic acid 
9-[(9Z)-octadecenoyloxy]octadecanoic acid 
9-Hexadecenoylcarnitine 
9-hydroxy hedychenone 
[(1S,3R,7S,8R,8aS)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate 
[(2S)-2-hydroxy-2-[(2S)-3-hydroxy-4,5-dioxooxolan-2-yl]ethyl] hexadecanoate 
[2-hydroxy-2-[(2R)-3-hydroxy-4,5-dioxooxolan-2-yl]ethyl] hexadecanoate 
[4,5-dihydroxy-3,4-bis(hydroxymethyl)-4a,8,8-trimethyl-5,6,7,8a-tetrahydro-1H-naphthalen-1-yl] hexanoate 
\{(2R,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)-5-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methoxytetrahydro-2H-pyran-2-yloxy]tetrahydrofuran-2-yl\}methyl nonanoate 
abiraterone acetate 
Acaranoic acid 
acemetacin  
acetylenic fatty ester +  
Acetylportentol 
Acevaltrate 
adefovir pivoxil  
aldono-1,5-lactone +  
all-trans-retinyl oleate 
all-trans-retinyl stearate 
Allyl cyclohexylpropionate 
Allyl isovalerate 
alpha-N-dichloroacetyl-p-aminophenylserinol 
amifostine  
amodiaquine +   
ampiroxicam 
ancitabine  
Anisatin 
Anopterine 
aripiprazole lauroxil 
arisugacin A 
arisugacin B 
arisugacin C 
arisugacin D 
ascorbyl dipalmitate 
ascorbyl palmitate 
Ascorbyl stearate 
azaribine  
azathioprine  
azilsartan kamedoxomil 
azilsartan medoxomil 
bacampicillin +  
baicalin  
balsalazide +   
bambuterol +   
bambuterol hydrochloride +  
Bathymodiolamide B 
beclomethasone dipropionate 
bempedoic acid 
benazepril  
benzyl 2-methyl-3-hydroxybutanoate +  
benzyl 2-methyl-3-oxobutanoate 
beta-erythroidine +   
bitolterol +  
botrallin 
botryosphaerin H 
Brialalepolide C 
bruceanol D 
bruceanol E 
bruceanol F 
bruceine D 
bruceolide +  
bufadienolides +   
butane-1,4-diol +   
butaverine 
Butonate 
Butyl 2-methylbutanoate 
Butyl 3-methylbutanoate 
butyl dec-9-enoate 
Butyl hexanoate 
butyl octadecanoate 
Butyl pentanoate 
butyrate ester +   
cabozantinib malate 
camptothecin  
capecitabine  
carbimazole  
cassiaside C2 
cefamandole nafate 
cefditoren pivoxil 
cefotiam hexetil dihydrochloride 
cefotiam hexetil ester +  
cefpodoxime proxetil 
ceftaroline fosamil +  
ceftaroline fosamil acetate +  
ceftaroline fosamil acetate monohydrate 
ceftobiprole medocaril 
CGP 78608 hydrochloride 
chaetomugilin A 
chaetomugilin D  
chaetoviridin B 
chaetoviridin D 
chrysopine +  
cilazapril +   
cilazapril monohydrate  
cleomiscosin A 
clorazepate monopotassium +  
clorazepic acid 
codeine +   
coetsin B 
Coixenolide 
colistimethate 
colistimethate sodium 
colossolactone VII 
colossolactone VIII 
compactin diol lactone 
coumestan +   
coumestrol +   
coumestrol diacetate 
cyathusal A 
cyathusal B 
cyathusal C 
cyprodenate 
cytosporic acid 
D-galactaro-1,4-lactone 
D-glucaro-1,4-lactone 
dabigatran etexilate 
dabigatran etexilate methanesulfonate 
dacarbazine  
decanoate ester +   
decursinol 
delta-cadinene +  
Deoxyanisatin 
dextilidine +  
dextromethorphan +   
Dibutyl adipate  
Diethyl adipate 
dihydro-beta-erythroidine  
Diisobutyl adipate 
Diisopropyl adipate 
Dimethyl citraconate 
dipivefrin 
dipotassium clorazepate 
dirithromycin 
dodecanoate ester +   
doxifluridine  
droxicam 
droxidopa 
dysolenticin A 
egonol oleate +  
egonol-2'''-methyl butanoate +  
egonol-2-methylpropanoate 
egonolbutanoate 
egonolpropanoate 
ekatetrone 
enalapril +   
enalapril maleate 
enanthate ester +   
Enicoflavine 
Enmein 
etanidazole  
ethionamide +   
ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate 
Ethyl 2-methylbut-2-enoate 
Ethyl 2-methylbutyrate 
Ethyl 3-acetoxy-2-methylbutyrate 
Ethyl 4-methylpentanoate 
Ethyl pentanoate 
Eunicea sesquiterpenoid 5 
Eunicea sesquiterpenoid 6 
Eupahyssopin 
eurycomanone  
FAHFA +  
famciclovir 
fatty acid ethyl ester +   
fatty acid methyl ester +   
FD-211 
fingolimod +  
fingolimod hydrochloride  
flucytosine  
fludarabine phosphate 
fluphenazine decanoate 
fluticasone furoate +  
fluvastatin  
fluvastatin sodium 
fosamprenavir 
fosaprepitant 
fosaprepitant dimeglumine 
Fosfluconazole 
fosinopril  
fosinopril sodium 
gabapentin enacarbil 
galaxolidone 
gemcitabine +   
Gemmacolide I, (rel)- 
Gemmacolide J, (rel)- 
Gemmacolide M, (rel)- 
Gentianaine 
Gentioflavine 
glycyrol  
gutolactone 
hallactone B 
heptanoic acid (2,2,6,6-tetramethyl-4-piperidinyl) ester 
heroin  
hexadecanoate ester +   
hexanoate ester +  
hexyl butyrate 
Hexyl dodecanoate 
hexyl propanoate 
hippeastrine 
Homobaldrinal 
hydroperoxy fatty ester +  
Ieodomycin B 
imidapril +   
interiotherin B 
interiotherin C 
inumakilactone 
inumakilactone B 
irinotecan  
irinotecan hydrochloride (anhydrous) +  
irinotecan hydrochloride hydrate 
isavuconazonium +  
isavuconazonium sulfate 
isoamyl isobutyrate 
Isoamyl isovalerate 
isobrucein A 
isocoumarins +   
Isodonal 
Isopropyl butyrate 
isopropyl dodecanoate 
isopropyl palmitate  
Isopropyl tetradecanoate 
isopropyl unoprostone 
isosojagol 
Isovaltrate 
ixazomib citrate 
Juncin O, (rel)- 
kadsuphilactone B 
kansuiphorin A 
kansuiphorin B 
L-Arabino-1,5-lactone 
L-dopa +  
lamellarin alpha 20-hydrogen sulfate 
lamesticumin F 
lamivudine  
lancilactone C 
laninamivir octanoate hydrate 
lapyrium chloride 
latanoprost  
leflunomide  
lefradafiban 
levomethorphan +  
Liatrin 
lovastatin +   
loxoprofen +   
LSM-4394 
LSM-4450 
lucanthone +   
Ludongnin F 
Ludongnin G 
Ludongnin H 
Ludongnin I 
maoecrystal Z 
Maoesin A, (rel)- 
Maoesin F 
Marasmic acid 
meadowlactone 
mestranol  
metamizole 
metamizole sodium  
Methyl (S)-2-Methylbutanoate 
Methyl 3-methylbutanoate 
Methyl 3-phenylpropanoate 
methyl 5-aminolevulinate +  
methyl 5-aminolevulinate hydrochloride 
methyl brevifolincarboxylate 
Methyl butyrate 
Methyl heptanoate 
methyl pentanoate 
metronidazole +   
metronidazole benzoate 
metronidazole hydrochloride 
mevastatin +   
mevinic acid 
mevinolinic acid 
midodrine  
minabeolide 1 
minabeolide 2 
minabeolide 4 
minabeolide 5 
minabeolide 8 
ML-236C +  
monacolin J +  
monacolin J acid 
monacolin L +  
monacolin L acid 
monapinone E +  
monobutyrin 
mycophenolate mofetil 
myrophine +  
N,O-dioleoylethanolamine 
N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
n-butyl oleate 
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-methylquipazine dimaleate 
nabumetone  
nagilactone F 
naproxcinod 
nelarabine 
nepafenac 
neurolenin A 
neurolenin B 
neurolenin C 
neurolenin D 
nimolicinol 
nitroglycerin  
nitrosulindac 
Nodosin  
norverapamil  
O-formylcefamandole 
O-oleoylanandamide 
obochalcolactone 
octadecanoate ester +  
octanoate ester +   
Officinoic acid A 
Officinoic acid B 
oleoyl danshenxinkun A 
oleoyl neocryptotanshinone 
olsalazine 
olsalazine sodium 
oseltamivir +   
palmariol B 
papulacandin +  
paraminabeolide A 
paraminabeolide B 
parecoxib  
pasireotide aspartate 
penamecillin 
Pentyl 3-methylbutanoate 
phelligridimer A 
phelligridin G 
pivampicillin 
pivmecillinam +  
Polyoxyethylene (600) monoricinoleate 
Polyoxyl 40 stearate 
polyunsaturated fatty ester +  
Portentol 
prasugrel 
pravastatin  
pravastatin lactone 
pravastatin sodium 
prednisolone phosphate 
prednisolone sodium phosphate 
prednisone +   
proglumetacin +  
Propyl 3-methylbutanoate 
propyl linoleate 
Propyl pentanoate 
psilocybin 
psilocybin(1-) 
psoralidin  
PX-866  
pyrazinecarboxamide  
Quadrone 
quassimarin 
quinapril 
R-mevalonolactone, (-)- 
rabdosichuanin A 
ramipril  
rel-3-((1S,2S,4R,6R,7S,9R,11R,12R)-2-Bromo-12-chloro-7-methyl-5,8,14-trioxa-tricyclo[9.2.1.0[4,6]]tetradec-9-yl)-acrylic acid methyl ester 
remdesivir  
ricinoleate ester 
rilpivirine hydrochloride +  
roducitabine 
rolitetracycline 
rubitecan  
salicin +   
salsalate  
samaderine E 
samaderine X 
samaderine Y 
samaderine Z 
sapacitabine 
saturated fatty ester C34H68O2 
saturated fatty ester C36H72O2 
saturated fatty ester C38H76O2 
saturated fatty ester C40H80O2 
saturated fatty ester C42H84O2 
saturated fatty ester C43H86O2 
saturated fatty ester C44H88O2 
saturated fatty ester C46H92O2 
SB 224289 hydrochloride 
schisanlactone A 
selexipag 
semiviriditoxin +  
Shikodonin 
simalikalactone D 
simvastatin  
A member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug.
sitoindoside I 
sitoindoside IX 
SN-38 +   
sodium phenylbutyrate 
sofosbuvir +  
sojagol 
soyasaponin III 
spirapril  
splitomicin  
staphyloxanthin 
Succinic acid, 2,2,3,3,4,4,5,5-octafluoropentyl 2-methylpent-3-yl ester 
sulfanegen 
sulindac +   
suxibuzone  
talampicillin +  
tazarotene  
tedizolid phosphate 
temozolomide  
tenofovir alafenamide 
tenofovir alafenamide fumarate +  
tenofovir disoproxil +   
tenofovir disoproxil fumarate  
tetradecanoate ester +   
tiazofurine  
Tiglyl tiglate 
tilidine 
trandolapril  
trans-2-Dodecenoylcarnitine 
trans-2-Tetradecenoylcarnitine 
travoprost 
tributyrin  
trichagmalin A 
trichagmalin B 
trichagmalin C +  
trichagmalin D 
trichagmalin E +  
trichagmalin F +  
trichanolide 
trifloroside 
tubocapsanolide A +  
tubocapsanolide F 
uracil +   
uridine triacetate 
valganciclovir 
Valtratum 
verapamil  
Vermeerin 
Vernolepin 
Vernomenin 
viscosalactone B 
wax ester +  
wedelolactone  
withaferin A +   
withalongolide A 
withalongolide B 
withalongolide C 
withalongolide D 
withalongolide E 
withalongolide F 
withalongolide G 
withalongolide H 
withalongolide I 
withalongolide J 
withalongolide K 
withalongolide L 
withalongolide M 
withalongolide N 
withanolide D +  
wortmannin +   
ximelagatran  
xylocarpin J 
yadanziolide B 
yadanziolide T 
yadanziolide U 
yadanziolide V 
zofenopril 
zofenopril calcium 

Synonyms
Exact Synonyms: (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
Related Synonyms: 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one ;   Formula=C25H38O5 ;   InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1 ;   InChIKey=RYMZZMVNJRMUDD-HGQWONQESA-N ;   MK-733 ;   SMILES=CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 ;   Simvastatina ;   Simvastatine ;   Simvastatinum ;   Zocor
Alternate IDs: CHEBI:45577
Xrefs: Beilstein:4768037 ;   CAS:79902-63-9 ;   DrugBank:DB00641 ;   Drug_Central:2445 ;   KEGG:D00434 ;   LINCS:LSM-2492
Xref Mesh: MESH:D019821
Xrefs: PMID:11336576 ;   PMID:12827636 ;   PMID:14561068 ;   PMID:14973129 ;   PMID:18199328 ;   PMID:18688862 ;   PMID:18936176 ;   Patent:EP33538 ;   Patent:US4444784 ;   Wikipedia:Simvastatin

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.